P-POD: Princeton Protein Orthology Database: GO3/Para554

This family has 22 members: 3 Arabidopsis thaliana, 2 Caenorhabditis elegans, 2 Danio rerio, 2 Dictyostelium discoideum, 1 Drosophila melanogaster, 2 Gallus gallus, 2 Homo sapiens, 2 Mus musculus, 2 Rattus norvegicus, 3 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/Para554
22 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_176768.1 · TAIR:locus:2009759 (F12P19_10 · F12P19.10 · AT1G65930)⌘
A. thalianaNCBI:NP_196963.2 · TAIR:locus:2222672 (T15N1_80 · T15N1.80 · AT5G14590)⌘
A. thalianaNCBI:NP_175836.1 · TAIR:locus:2020128 (F20D21_16 · AT1G54340 · F20D21.16 · ICDH)ISOCITRATE DEHYDROGENASE⌘
C. elegansWB:WBGene00007942 (C34F6.8 · idh-2) · UniProtKB:O17643⌘
C. elegansWB:WBGene00010317 (F59B8.2 · idh-1) · UniProtKB:Q21032⌘
D. rerioUniProtKB:Q802Y2 · ZFIN:ZDB-GENE-031006-1 (idh1)isocitrate dehydrogenase 1 (NADP+), soluble⌘
D. rerioUniProtKB:Q7ZUP6 · ZFIN:ZDB-GENE-031118-95 (idh2)isocitrate dehydrogenase 2 (NADP+), mitochondrial⌘
D. discoideumUniProtKB:Q75JR3 · dictyBase:DDB_G0272208 (idhC)isocitrate dehydrogenase (NADP+), isocitrate dehydrogenase (NADP+), cytosolic⌘
D. discoideumUniProtKB:Q75JR2 · dictyBase:DDB_G0272210 (idhM)isocitrate dehydrogenase (NADP+), isocitrate dehydrogenase (NADP+), mitochondrial⌘
D. melanogasterUniProtKB:Q7KUB1 · FB:FBgn0001248 (l(3)L3852 · CG7176 · IDH · CT22171 · IDH-NADP · Idh · Idh-NADP · NADP-IDH · idh)Isocitrate dehydrogenase⌘
G. gallusNCBI:XP_421965 · ENTREZ:424112
G. gallusENTREZ:431056 · UniProtKB:Q5ZL82 (IPI00577774 · RCJMB04_7e11 · Q5ZL82)⌘
H. sapiensENSEMBL:ENSG00000138413 · UniProtKB:O75874 (IPI00027223 · PICD · O75874 · IDH1 · IDHC_HUMAN)Isocitrate dehydrogenase [NADP] cytoplasmic⌘
H. sapiensENSEMBL:ENSG00000182054 · UniProtKB:P48735 (IPI00011107 · IDHP_HUMAN · P48735 · IDH2)Isocitrate dehydrogenase [NADP], mitochondrial⌘
M. musculusUniProtKB:O88844 · MGI:MGI:96413 (IDPc · Idh1 · Idh-1 · Id-1)isocitrate dehydrogenase 1 (NADP+), soluble⌘
M. musculusUniProtKB:P54071 · MGI:MGI:96414 (Idh2 · IDPm · Idh-2)isocitrate dehydrogenase 2 (NADP+), mitochondrial⌘
R. norvegicusUniProtKB:P41562 · RGD:2862 (Idh1)isocitrate dehydrogenase 1 (NADP+), soluble⌘
R. norvegicusUniProtKB:P56574 · RGD:1597139 (Idh2)isocitrate dehydrogenase 2 (NADP+), mitochondrial⌘
S. cerevisiaeUniProtKB:P41939 · SGD:S000004164 (IDP2 · YLR174W)Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate⌘
S. cerevisiaeUniProtKB:P53982 · SGD:S000004954 (YNL009W · IDP3)Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids⌘
S. cerevisiaeUniProtKB:P21954 · SGD:S000002224 (YDL066W · IDP1)Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate⌘
S. pombeUniProtKB:O14254 · GeneDB_Spombe:SPAC6G10.08 (SPAC6G10.08 · idp1)isocitrate dehydrogenase Idp1⌘
ProteinPublicationCurator Notes
UniProtKB:P41939 · SGD:S000004164PMID:18275837 Lu Q, et al. Dual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeast. Arch Biochem Biophys. 2008 Apr 1;472(1):17-25.The M. musculus protein Idh1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P53982 · SGD:S000004954PMID:18275837 Lu Q, et al. Dual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeast. Arch Biochem Biophys. 2008 Apr 1;472(1):17-25.The M. musculus protein Idh1 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000138413 · UniProtKB:O75874#137800 GLIOMA OF BRAIN, FAMILIALGLIOBLASTOMA MULTIFORME, INCLUDED; GLM, INCLUDED; GBM, INCLUDED;;ASTROCYTOMA, INCLUDED;;OLIGODENDROGLIOMA, INCLUDED
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