P-POD: Princeton Protein Orthology Database: GO3/Para453

This family has 97 members: 17 Arabidopsis thaliana, 7 Caenorhabditis elegans, 8 Danio rerio, 10 Dictyostelium discoideum, 5 Drosophila melanogaster, 4 Gallus gallus, 7 Homo sapiens, 13 Mus musculus, 16 Rattus norvegicus, 6 Saccharomyces cerevisiae, 4 Schizosaccharomyces pombe.

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GO3/Para453
97 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2028005 (F26F24.28 · F26F24_28 · AT1G23410) · NCBI:NP_173755.1⌘
A. thalianaNCBI:NP_564379.2 · TAIR:locus:2197525 (T19E23.13 · AT1G31340 · NEDD8 · RUB1 · T19E23_13 · ATRUB1)RELATED TO UBIQUITIN 1 · ARABIDOPSIS THALIANA RELATED TO UBIQUITIN 1⌘
A. thalianaNCBI:NP_849299.1 · TAIR:locus:2115663 (C17L7.240 · C17L7_240 · UBQ10 · AT4G05320)POLYUBIQUITIN 10⌘
A. thalianaNCBI:NP_566357.1 · TAIR:locus:2074909 (AT3G09790 · F11F8.38 · UBQ8)⌘
A. thalianaNCBI:NP_566969.1 · TAIR:locus:2079924 (ERD16 · UBQ1 · F3C22.8 · HAP4 · AT3G52590 · EMB2167)EMBRYO DEFECTIVE 2167 · UBIQUITIN EXTENSION PROTEIN 1 · HAPLESS 4 · EARLY-RESPONSIVE TO DEHYDRATION 16⌘
A. thalianaNCBI:NP_849292.1 · TAIR:locus:2140200 (T5J8.21 · UBQ14 · AT4G02890 · T5J8_21)⌘
A. thalianaNCBI:NP_568552.1 · TAIR:locus:2151774 (K12B20.90 · UBQ9 · K12B20_90 · AT5G37640)⌘
A. thalianaNCBI:NP_851029.1 · TAIR:locus:2143548 (UBQ3 · F15A17.270 · F15A17_270 · AT5G03240)POLYUBIQUITIN 3 PROTEIN · POLYUBIQUITIN 3⌘
A. thalianaNCBI:NP_568397.1 · TAIR:locus:2180434 (T1M15.20 · AT5G20620 · UBQ4 · T1M15_20)⌘
A. thalianaNCBI:NP_172662.1 · TAIR:locus:2008950 (F12F1_15 · F12F1.15 · RUB3 · AT1G11980)UBIQUITIN-RELATED PROTEIN 3⌘
A. thalianaNCBI:NP_565812.1 · TAIR:locus:505006295 (UBQ7 · AT2G35635 · RUB2)RELATED TO UBIQUITIN 2⌘
A. thalianaNCBI:NP_176714.1 · TAIR:locus:2206310 (UBQ13 · T8F5.13 · AT1G65350 · T8F5_13)⌘
A. thalianaNCBI:NP_566095.1 · TAIR:locus:2041459 (UBQ6 · AT2G47110 · F14M4.6)⌘
A. thalianaNCBI:NP_565836.1 · TAIR:locus:2053496 (AT2G36170 · F9C22_10 · F9C22.10)⌘
A. thalianaNCBI:NP_191784.1 · TAIR:locus:2098003 (T17J13.210 · UBQ5 · AT3G62250)ubiquitin 5⌘
A. thalianaNCBI:NP_567286.1 · TAIR:locus:2138386 (UBQ11 · AT4G05050 · C17L7.6)UBIQUITIN 11⌘
A. thalianaNCBI:NP_564675.1 · TAIR:locus:2827139 (AT1G55060 · T7N22.10 · UBQ12)UBIQUITIN 12⌘
C. elegansWB:WBGene00003587 (F45H11.2 · ned-8) · UniProtKB:Q93725 (F45H11.2 · NEDD8_CAEEL · NEDD8 · ned-8)⌘⌘
C. elegansWB:WBGene00006725 (H06I04.4 · ubl-1) · UniProtKB:P37165⌘
C. elegansWB:WBGene00006727 (ubq-1 · F25B5.4) · UniProtKB:P14792 (ubq-2 · ubib · UBIQ_CAEEL · ubq-1 · F25B5.4 · ubia · ZK1010.1 · Ubiquitin)⌘⌘
C. elegansUniProtKB:P14792 (ubq-2 · ubib · UBIQ_CAEEL · ubq-1 · F25B5.4 · ubia · ZK1010.1 · Ubiquitin) · WB:WBGene00006728 (ubq-2 · ZK1010.1)⌘⌘
C. elegansWB:WBGene00009378 · UniProtKB:Q09557
C. elegansWB:WBGene00018661 (F52C6.4) · UniProtKB:O44819⌘
C. elegansWB:WBGene00010654 · UniProtKB:Q9XUT3
D. rerioENSEMBL:ENSDARP00000088354
D. rerioENSEMBL:ENSDARG00000056851 · UniProtKB:A2BHB8
D. rerioUniProtKB:Q3B7P7 · ZFIN:ZDB-GENE-051023-7 (uba52)ubiquitin A-52 residue ribosomal protein fusion product 1⌘
D. rerioUniProtKB:Q6DGU4 · ZFIN:ZDB-GENE-040718-295 (nedd8l)neural precursor cell expressed, developmentally down-regulated 8, like⌘
D. rerioZFIN:ZDB-GENE-050411-10 (zgc:172187) · UniProtKB:Q6IS68⌘
D. rerioUniProtKB:Q7SXD9 · ZFIN:ZDB-GENE-030616-588 (nedd8)neural precursor cell expressed, developmentally down-regulated 8⌘
D. rerioZFIN:ZDB-GENE-030131-10018 (zgc:66168) · UniProtKB:Q7ZU62⌘
D. rerioZFIN:ZDB-GENE-040426-1089 (zgc:56596) · UniProtKB:Q7ZWB2⌘
D. discoideumNCBI:EAL61494.1 · dictyBase:DDB_G0291928 (ubqI · ubiquitin)⌘
D. discoideumNCBI:EAL66269.1 · dictyBase:DDB_G0282295 (ubiquitin · ubqA)⌘
D. discoideumNCBI:EAL67635.1 · dictyBase:DDB_G0279721 (ubqH · ubiquitin)⌘
D. discoideumNCBI:EAL62704.1 · dictyBase:DDB_G0289449 (ubqF · ubiquitin)⌘
D. discoideumNCBI:EAL72079.1 · dictyBase:DDB_G0269458 (ubqJ · ubiquitin)⌘
D. discoideumNCBI:EAL63951.1 · dictyBase:DDB_G0286907 (ubqE · ubqD · ubiquitin)⌘
D. discoideumNCBI:EAL67035.1 · dictyBase:DDB_G0280755 (ubqB · rpl40)ubiquitin/ribosomal protein L40 fusion protein⌘
D. discoideumNCBI:EAL66044.1 · dictyBase:DDB_G0282369 (rcdLL · veg116 · ubqG · ubiquitin)⌘
D. discoideumNCBI:EAL68884.1 · dictyBase:DDB_G0276765 (rps27a · ubqC)ubiquitin/ribosomal protein S27a fusion protein⌘
D. discoideumUniProtKB:Q54XV3 · dictyBase:DDB_G0278711 (nedd8)neddylin, ubiquitin-like protein Nedd8⌘
D. melanogasterUniProtKB:Q9VJ33 · FB:FBgn0032725 (nedd8 · CG10679 · Nedd8)neural precursor cell-expressed developmentally downregulated⌘
D. melanogasterUniProtKB:P15357 · FB:FBgn0003942 (Ubiquitin-monomeric · UB3-D · ubiquitin · Ubiquitin · CG5271 · Ubi-m · DUb80 · Dub80 · mfs(2)31 · Ubi-f80 · mfs(2)48 · RpS27A · Ubiq · mfs48 · l(2)04820 · l(2)31Ei)male female sterile 31 · Ubiquitin fusion 80 · Ribosomal protein S27A⌘
D. melanogasterFB:FBgn0003943 (DmUb · ubi63E · Ubp · Ubi-p · polyubiquitin · Ubi-p63E · ubiquitin · Ubiquitin-polymeric · Ubiquitin · Ubiquitin-63E · Ub · Ubiq · CG11624 · Ubip · Ubi63E · Ubi63p) · UniProtKB:P68198⌘
D. melanogasterFB:FBgn0038571 (CG7215 · CG32920) · UniProtKB:Q9VEC8⌘
D. melanogasterFB:FBgn0086558 (CG18282 · ubiquitin · CR32744 · Ubi-p5E · Ubiquitin · Ub · Ubiq · Ubiquitin-5E · CG32744) · UniProtKB:Q9W418⌘
G. gallusNCBI:NP_001072942 · ENTREZ:396425
G. gallusNCBI:XP_415105 · ENTREZ:396190
G. gallusNCBI:NP_990284 · ENTREZ:395796
G. gallusUniProtKB:O42388 (O42388 · IPI00589085) · ENTREZ:395958⌘
H. sapiensENSEMBL:ENSG00000129559 · UniProtKB:Q15843 (NEDD8 · Q15843 · NEDD8_HUMAN · IPI00020008)⌘
H. sapiensENSEMBL:ENSG00000143947 · UniProtKB:P62979 (UBCEP1 · UBA80 · RS27A_HUMAN · P62979 · IPI00179330 · RPS27A)40S ribosomal protein S27a⌘
H. sapiensENSEMBL:ENSG00000206468 · UniProtKB:O15205 (UBD_HUMAN · O15205 · UBD · FAT10 · IPI00007405)Ubiquitin D⌘
H. sapiensENSEMBL:ENSG00000150991 · UniProtKB:P62988 (UBCEP1 · UBA80 · UBA52 · UBIQ_HUMAN · UBC · Ubiquitin · UBB · P62988 · IPI00798155 · UBCEP2 · RPS27A)⌘
H. sapiensUniProtKB:P62988 (UBCEP1 · UBA80 · UBA52 · UBIQ_HUMAN · UBC · Ubiquitin · UBB · P62988 · IPI00798155 · UBCEP2 · RPS27A) · ENSEMBL:ENSG00000170315⌘
H. sapiensENSEMBL:ENSG00000102178 · UniProtKB:P11441 (GDX · DXS254E · P11441 · IPI00005658 · UBL4A_HUMAN · UBL4 · UBL4A)Ubiquitin-like protein 4A⌘
H. sapiensENSEMBL:ENSG00000187608 · UniProtKB:P05161 (UCRP_HUMAN · IPI00375631 · UCRP · ISG15 · P05161 · G1P2)Interferon-induced 17 kDa protein⌘
M. musculusNCBI:XP_356994 · MGI:MGI:3648788
M. musculusMGI:MGI:3644625 · NCBI:XP_985698
M. musculusNCBI:NP_001098627 · MGI:MGI:3649356 (OTTMUSG00000004411)predicted gene, OTTMUSG00000004411⌘
M. musculusNCBI:XP_915304 · MGI:MGI:3647845
M. musculusNCBI:XP_889611 · MGI:MGI:3643614
M. musculusNCBI:XP_001471736 · MGI:MGI:3809535
M. musculusNCBI:XP_994469 · MGI:MGI:3643360
M. musculusNCBI:XP_001002242 · MGI:MGI:3645406
M. musculusUniProtKB:P29595 · MGI:MGI:97301 (Rub1 · Nedd8)neural precursor cell expressed, developmentally down-regulated gene 8⌘
M. musculusUniProtKB:P62983 · MGI:MGI:1925544 (Rps27a)ribosomal protein S27A⌘
M. musculusUniProtKB:P63072 · MGI:MGI:1344410 (Diubiquitin · Ubd · FAT10)ubiquitin D⌘
M. musculusUniProtKB:P21126 · MGI:MGI:95049 (Gdx · DXHXS254E · Ubl4 · DXS254Eh)ubiquitin-like 4⌘
M. musculusUniProtKB:Q64339 · MGI:MGI:1855694 (G1p2 · Isg15)ISG15 ubiquitin-like modifier⌘
R. norvegicusNCBI:XP_001066030 · RGD:1588826 (LOC688462)similar to ribosomal protein S27a⌘
R. norvegicusNCBI:XP_001060577 · RGD:1598012 (LOC681260)similar to ribosomal protein S27a⌘
R. norvegicusNCBI:XP_216605 · RGD:1310312
R. norvegicusNCBI:XP_574121 · RGD:1564290 (RGD1564290)similar to ribosomal protein S27a⌘
R. norvegicusNCBI:XP_001080565 · RGD:1597537
R. norvegicusNCBI:XP_001068457 · RGD:1595237
R. norvegicusNCBI:XP_001060776 · RGD:1598057 (LOC681214)similar to ribosomal protein S27a⌘
R. norvegicusNCBI:XP_001057026 · RGD:1598094 (LOC679976)similar to ribosomal protein S27a⌘
R. norvegicusNCBI:XP_215228 · RGD:1563983 (Ubl4)ubiquitin-like 4⌘
R. norvegicusNCBI:XP_001053937 · RGD:1560997 (RGD1560997)similar to ribosomal protein S27a⌘
R. norvegicusUniProtKB:Q71UE8 · RGD:3158 (Nedd8)neural precursor cell expressed, developmentally down-regulated 8⌘
R. norvegicusUniProtKB:P62982 · RGD:620240 (Rps27a)ribosomal protein S27a⌘
R. norvegicusUniProtKB:Q921A3 · RGD:69418 (Ubd)ubiquitin D⌘
R. norvegicusUniProtKB:Q63429 · RGD:621244 (Ubc)ubiquitin C⌘
R. norvegicusUniProtKB:Q63654 · RGD:621562 (Ubb)ubiquitin B⌘
R. norvegicusNCBI:XP_577989 · RGD:1562896
S. cerevisiaeNCBI:NP_013061 · SGD:S000003962 (UB14 · UBI4 · YLL039C · SCD2)Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system⌘
S. cerevisiaeUniProtKB:Q12285 · SGD:S000005471 (GET5 · MDY2 · TMA24 · YOL111C)Protein required for efficient mating⌘
S. cerevisiaeUniProtKB:P05759 · SGD:S000004157 (RPS37 · RPS31 · YLR167W · UBI3)Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin⌘
S. cerevisiaeUniProtKB:Q03919 · SGD:S000002546 (RUB1 · YDR139C)Ubiquitin-like protein with similarity to mammalian NEDD8⌘
S. cerevisiaeUniProtKB:P61864 · SGD:S000001802 (UB12 · RPL40B · UBI2 · CEP52B · YKR094C)Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40⌘
S. cerevisiaeUniProtKB:P61864 · SGD:S000001410 (UBI1 · YIL148W · CEP52A · RPL40A · UB11)Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40⌘
S. pombeUniProtKB:P0C016 · GeneDB_Spombe:SPAC6G10.11c (SPAC6G10.11c · ubi3)ribosomal-ubiquitin fusion protein Ubi3⌘
S. pombeGeneDB_Spombe:SPBC337.08c (ubi4 · SPBC337.08c · ubiquitin) · UniProtKB:P0C014⌘
S. pombeUniProtKB:O14399 · GeneDB_Spombe:SPBC12D12.08c (ubl1 · nedd8 · SPBC24C6.01c · ned8 · SPBC12D12.08c)ubiquitin-like protein modifier Ned8⌘
S. pombeUniProtKB:Q9HDZ4 · GeneDB_Spombe:SPAC589.10c (SPAC589.10c)ribomal-ubiquitin fusion protein Ubi5⌘
ProteinPublicationCurator Notes
UniProtKB:P61864 · SGD:S000001410PMID:15790562 Shang F, et al. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem. 2005 May 27;280(21):20365-74.The S. cerevisiae protein RPL40A was expressed in E. coli, but complementation was not directly tested. This paper describes the biochemical characterization of ubiquitins produced in several expression systems.
UniProtKB:P61864 · SGD:S000001802PMID:15790562 Shang F, et al. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem. 2005 May 27;280(21):20365-74.The S. cerevisiae protein RPL40B was expressed in E. coli, but complementation was not directly tested. This paper describes the biochemical characterization of ubiquitins produced in several expression systems.
UniProtKB:P05759 · SGD:S000004157PMID:15790562 Shang F, et al. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem. 2005 May 27;280(21):20365-74.The S. cerevisiae protein RPS31 was expressed in E. coli, but complementation was not directly tested. This paper describes the biochemical characterization of ubiquitins produced in several expression systems.
NCBI:NP_013061 · SGD:S000003962PMID:15790562 Shang F, et al. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem. 2005 May 27;280(21):20365-74.The S. cerevisiae protein UBI4 was expressed in E. coli, but complementation was not directly tested. This paper describes the biochemical characterization of ubiquitins produced in several expression systems.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
SGD Disease Papers (1)
NCBI:NP_013061 · SGD:S000003962PMID:12709439 Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu