P-POD: Princeton Protein Orthology Database: GO3/Para16080

This family has 3 members: 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/Para16080
3 members.
OrganismProtein (Synonyms)DescriptionAmiGO
S. cerevisiaeUniProtKB:Q04409 · SGD:S000002924 (YDR516C · EMI2)Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1⌘
S. cerevisiaeUniProtKB:P17709 · SGD:S000000545 (GLK1 · HOR3 · YCL040W)Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism⌘
S. pombeUniProtKB:P50521 · GeneDB_Spombe:SPAC4F8.07c (hxk2 · SPAC4F8.07c)hexokinase 2⌘
ProteinPublicationCurator Notes
UniProtKB:P17709 · SGD:S000000545PMID:9112782 Kanayama Y, et al. Divergent fructokinase genes are differentially expressed in tomato. Plant Physiol. 1997 Apr;113(4):1379-84.The L. esculentum protein Frk1 complements a homologous mutation in S. cerevisiae. Tomato Frk1 complements a yeast glk1 hxk1 hxk2 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:9576777 Kanayama Y, et al. Tomato fructokinases exhibit differential expression and substrate regulation. Plant Physiol. 1998 May;117(1):85-90.The L. esculentum protein Frk1 complements a homologous mutation in S. cerevisiae. Tomato Frk1 complements a yeast glk1 hxk1 hxk2 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK1 complements a homologous mutation in S. cerevisiae. Rice HXK1 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:14507429 Bonini BM, et al. Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae Tps1 mutants expressing trehalose-6-phosphate-insensitive hexokinase from Schizosaccharomyces pombe. Biochim Biophys Acta. 2003 Sep 30;1606(1-3):83-93.The S. pombe protein Hxk2 complements a homologous mutation in S. cerevisiae. S. pombe Hxk2 rescues an S. cerevisiae hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:10482667 Veramendi J, et al. Antisense repression of hexokinase 1 leads to an overaccumulation of starch in leaves of transgenic potato plants but not to significant changes in tuber carbohydrate metabolism. Plant Physiol. 1999 Sep;121(1):123-34.The S. tuberosum protein StHK1 complements a homologous mutation in S. cerevisiae. Potato hexokinase 1 complements a yeast glk1 hxk1 hxk2 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:9576777 Kanayama Y, et al. Tomato fructokinases exhibit differential expression and substrate regulation. Plant Physiol. 1998 May;117(1):85-90.The L. esculentum protein Frk2 complements a homologous mutation in S. cerevisiae. Tomato Frk2 complements a yeast glk1 hxk1 hxk2 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK10 complements a homologous mutation in S. cerevisiae. Rice HXK10 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK2 complements a homologous mutation in S. cerevisiae. Rice HXK2 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK3 complements a homologous mutation in S. cerevisiae. Rice HXK3 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK4 complements a homologous mutation in S. cerevisiae. Rice HXK4 lacking a putative chloroplast-targeting sequence complements a yeast hxk1 hxk2 glk1 triple mutant, but full-length HXK4 does not.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK5 complements a homologous mutation in S. cerevisiae. Rice HXK5 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK6 complements a homologous mutation in S. cerevisiae. Rice HXK6 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK7 complements a homologous mutation in S. cerevisiae. Rice HXK7 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK8 complements a homologous mutation in S. cerevisiae. Rice HXK8 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:16552590 Cho JI, et al. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta. 2006 Aug;224(3):598-611.The O. sativa protein OsHXK9 complements a homologous mutation in S. cerevisiae. Rice HXK9 complements a yeast hxk1 hxk2 glk1 triple mutant.
UniProtKB:P17709 · SGD:S000000545PMID:11164592 Menu T, et al. Cloning and characterization of a cDNA encoding hexokinase from tomato. Plant Sci. 2001 Jan 5;160(2):209-218.The L. esculentum protein LeHXK2 complements a homologous mutation in S. cerevisiae. This paper shows that L. esculentum LEHXK2 complements a yeast hxk1 hxk2 glk1 triple mutant which lacks the ability to phosphorylate glucose and fructose.
UniProtKB:P17709 · SGD:S000000545PMID:11571755 Mayordomo I, et al. Human pancreatic glucokinase (GlkB) complements the glucose signalling defect of Saccharomyces cerevisiae hxk2 mutants. Yeast. 2001 Oct;18(14):1309-16.The H. sapiens protein P35557 complements a homologous mutation in S. cerevisiae. This paper shows that human GCK rescues a yeast hxk1 hxk2 glk1 triple mutant.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
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