This family has 24 members: 3 Arabidopsis thaliana, 1 Caenorhabditis elegans, 4 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 2 Gallus gallus, 3 Homo sapiens, 3 Mus musculus, 3 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
Interactive Java Applets: Notung Tree Analysis · Jalview Alignment
| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | NCBI:NP_193699.1 · TAIR:locus:2123010 (RAB-F2B · ARA-7 · F24J7_190 · RABF2B · ATRABF2B · ATRAB5B · ATRAB-F2B · F24J7.190 · AT4G19640 · ARA7) | RAB GTPASE HOMOLOG F2B · ARABIDOPSIS RAB GTPASE HOMOLOG F2B |  |
| A. thaliana | NCBI:NP_199326.1 · TAIR:locus:2153202 (ATRAB-F2A · K17O22.15 · K17O22_15 · AT5G45130 · RAB5A · ATRABF2A · RAB-F2A · ATRAB5A · RHA1 · RABF2A) | RAB HOMOLOG 1 · RAB HOMOLOG F2A · ARABIDOPSIS RAB HOMOLOG F2A | |
| A. thaliana | NCBI:NP_567008.1 · TAIR:locus:2082672 (ATRAB5C · ATRABF1 · ARA6 · ARA-6 · RABF1 · F28P10.180 · AT3G54840) | | |
| C. elegans | WB:WBGene00004268 (F26H9.6 · rab-5) · UniProtKB:P91857 | | |
| D. rerio | UniProtKB:Q6NYD6 · ZFIN:ZDB-GENE-040426-2593 (rab5b) | RAB5B, member RAS oncogene family | |
| D. rerio | UniProtKB:Q7ZUG4 · ZFIN:ZDB-GENE-040122-3 (rab5al) | RAB5A, member RAS oncogene family like | |
| D. rerio | UniProtKB:Q7ZUW5 · ZFIN:ZDB-GENE-030131-139 (rab5a) | RAB5A, member RAS oncogene family | |
| D. rerio | UniProtKB:Q7ZVP2 · ZFIN:ZDB-GENE-031118-30 (rab5c) | RAB5C, member RAS oncogene family | |
| D. discoideum | UniProtKB:Q86JP3 · dictyBase:DDB_G0271984 (rab5A) | Rab GTPase | |
| D. melanogaster | UniProtKB:Q9V3I2 · FB:FBgn0014010 (BAA88244 · CG3664 · Rab5 · dRab5 · Rab · Drab5 · rab5 · RAB5 · DmRab5 · l(2)k08232 · DRab5 · AAF51265 · RAB5a) | Dm Rab5 · Rab-protein 5 | |
| G. gallus | ENTREZ:395197 · UniProtKB:Q98932 (RAB5C · Q98932 · RAB5C_CHICK · IPI00600808) | Ras-related protein Rab-5C | |
| G. gallus | UniProtKB:Q5ZIP7 (IPI00596261 · Q5ZIP7 · RCJMB04_24h4) · ENTREZ:420649 | | |
| H. sapiens | ENSEMBL:ENSG00000144566 · UniProtKB:P20339 (RAB5A_HUMAN · RAB5 · RAB5A · P20339 · IPI00023510) | Ras-related protein Rab-5A | |
| H. sapiens | ENSEMBL:ENSG00000111540 · UniProtKB:P61020 (P61020 · RAB5B_HUMAN · RAB5B · IPI00017344) | Ras-related protein Rab-5B | |
| H. sapiens | ENSEMBL:ENSG00000108774 · UniProtKB:P51148 (RAB5C_HUMAN · RAB5C · IPI00016339 · RABL · P51148) | Ras-related protein Rab-5C | |
| M. musculus | UniProtKB:Q9CQD1 · MGI:MGI:105926 (Rab5a) | RAB5A, member RAS oncogene family | |
| M. musculus | UniProtKB:P61021 · MGI:MGI:105938 (Rab5b) | RAB5B, member RAS oncogene family | |
| M. musculus | UniProtKB:P35278 · MGI:MGI:105306 (Rab5c) | RAB5C, member RAS oncogene family | |
| R. norvegicus | NCBI:XP_001081435 · RGD:1307095 (Rab5c) | RAB5C, member RAS oncogene family | |
| R. norvegicus | UniProtKB:A1L1J8 · RGD:1306489 (Rab5b) | RAB5B, member RAS oncogene family | |
| R. norvegicus | UniProtKB:O88565 (RAB5 · O88565 · IPI00210733 · rCG_35613 · Rab5a) · RGD:620936 (Rab5a) | RAB5A, member RAS oncogene family | |
| S. cerevisiae | UniProtKB:P36017 · SGD:S000005615 (VPT12 · VPS12 · VPS21 · YPT21 · YPT51 · YOR089C) | GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases | |
| S. cerevisiae | UniProtKB:P36019 · SGD:S000005037 (YNL093W · YPT53) | GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5 | |
| S. pombe | UniProtKB:P36586 · GeneDB_Spombe:SPAC6F6.15 (ypt5 · SPAC6F6.15) | GTPase Ypt5 | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| SGD Disease Papers (1) | |
|---|---|
| UniProtKB:P36017 · SGD:S000005615 |  18634833 Zabrocki P, et al. (2008) Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson. Biochim Biophys Acta 1783(10):1767-80 |