P-POD: Princeton Protein Orthology Database: GO3/Para1525

This family has 52 members: 15 Arabidopsis thaliana, 3 Caenorhabditis elegans, 5 Danio rerio, 4 Dictyostelium discoideum, 2 Drosophila melanogaster, 5 Gallus gallus, 4 Homo sapiens, 4 Mus musculus, 3 Rattus norvegicus, 3 Saccharomyces cerevisiae, 4 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Para1525
52 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_173823.1 · TAIR:locus:2032452 (F3I6.5 · AT1G24130 · F3I6_5)⌘
A. thalianaNCBI:NP_180217.1 · TAIR:locus:2066276 (T9J22.16 · AT2G26490 · T9J22_16)⌘
A. thalianaNCBI:NP_175369.1 · TAIR:locus:2010157 (F13F21_11 · AT1G49450 · F13F21.11)⌘
A. thalianaNCBI:NP_190608.2 · TAIR:locus:2074825 (F11C1.230 · AT3G50390)⌘
A. thalianaNCBI:NP_564219.1 · TAIR:locus:2024031 (AT1G24530 · F21J9.19)⌘
A. thalianaNCBI:NP_175192.1 · TAIR:locus:2015423 (F16N3_9 · F16N3.9 · AT1G47610)⌘
A. thalianaNCBI:NP_188525.1 · TAIR:locus:2085929 (AT3G18950 · K13E13.12)⌘
A. thalianaNCBI:NP_190761.1 · TAIR:locus:2083710 (AT3G51930 · F4F15.40)⌘
A. thalianaNCBI:NP_001032059.1 · TAIR:locus:2173103 (MSG15.6 · AT5G51980 · MSG15_6)⌘
A. thalianaNCBI:NP_195164.1 · TAIR:locus:2116194 (F10M10.150 · AT4G34380 · F10M10_150)⌘
A. thalianaNCBI:NP_198904.1 · TAIR:locus:2164456 (MHK7_11 · MHK7.11 · AT5G40880)⌘
A. thalianaNCBI:NP_199823.1 · TAIR:locus:2170061 (MPF21_14 · AT5G50120 · MPF21.14)⌘
A. thalianaNCBI:NP_568408.1 · TAIR:locus:2147077 (AT5G21040 · T10F18.1 · FBX2)F-BOX PROTEIN 2⌘
A. thalianaNCBI:NP_199731.1 · TAIR:locus:2155904 (K21P3_7 · AT5G49200 · K21P3.7)⌘
A. thalianaNCBI:NP_194274.2 · TAIR:locus:2131799 (T30C3.6 · ZFWD1 · AT4G25440)zinc finger WD40 repeat protein 1⌘
C. elegansWB:WBGene00003009 (K10B2.1 · lin-23) · UniProtKB:Q09990 (LIN23_CAEEL · K10B2.1 · lin-23)F-box/WD repeat-containing protein lin-23⌘⌘
C. elegansWB:WBGene00003047 (lis-1 · T03F6.5) · UniProtKB:Q9NDC9⌘
C. elegansWB:WBGene00004767 (F55B12.3 · sel-10) · UniProtKB:Q93794 (F55B12.3 · egl-41 · SEL10_CAEEL · sel-10)F-box/WD repeat-containing protein sel-10⌘⌘
D. rerioENSEMBL:ENSDARP00000080947
D. rerioUniProtKB:Q7T394 · ZFIN:ZDB-GENE-040116-2 (pafah1b1a)platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a⌘
D. rerioUniProtKB:Q803D2 · ZFIN:ZDB-GENE-040116-3 (pafah1b1b)platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b⌘
D. rerioUniProtKB:Q6PGW4 · ZFIN:ZDB-GENE-040426-2903 (fbxw11b)F-box and WD-40 domain protein 11b⌘
D. rerioZFIN:ZDB-GENE-030131-6305 · UniProtKB:Q7ZVZ1
D. discoideumNCBI:EAL60966.1 · dictyBase:DDB_G0292834 (DDB_G0292834)cyclin-like F-box containing protein, WD40 repeat-containing protein⌘
D. discoideumUniProtKB:Q8I0F4 · dictyBase:DDB_G0288375 (lis1)putative dynein regulator, lissencephaly type-1-like homology (LisH) motif-containing protein, WD40 repeat-containing protein⌘
D. discoideumdictyBase:DDB_G0291716 · UniProtKB:Q54E65
D. discoideumdictyBase:DDB_G0286129 · UniProtKB:Q54M93
D. melanogasterUniProtKB:Q7KNS3 · FB:FBgn0015754 (DLis-1 · DLIS-1 · Dlis-1 · n(2)k11702 · LIS-1 · l(2R)W8 · DLIS1 · l(2)k13209 · Lissencephaly-1 · lis-1 · lis1 · Lis-1 · Paf-AHbeta · CG8440 · DLis1 · D-Lis1 · Lis1 · DmLIS1 · dLis1)platelet-activating factor acetylhydrolase Ib beta-subunit homolog · Lis 1⌘
D. melanogasterUniProtKB:Q9VDE3 · FB:FBgn0023423 (icare · CG3412 · Slimb/Beta-TRCP1 · l(3)00295 · ica · Slimb/beta-TRCP · shv · shiva · slmb · BcDNA:GM02031 · slimb · SLIMB · crd · Slimb · pingiel · Slmb)centrosome replication defective · supernumerary limbs⌘
G. gallusNCBI:XP_421723 · ENTREZ:423854
G. gallusNCBI:XP_420447 · ENTREZ:422481
G. gallusNCBI:XP_417265 · ENTREZ:419074
G. gallusENTREZ:374224 · UniProtKB:Q9PTR5 (LIS1_CHICK · Q9PTR5 · PAFAH1B1 · LIS1 · IPI00596826)Platelet-activating factor acetylhydrolase IB subunit alpha⌘
G. gallusUniProtKB:Q5ZHQ9 · ENTREZ:416181
H. sapiensENSEMBL:ENSG00000166167 · UniProtKB:Q9Y297 (IPI00413142 · Q9Y297 · FBW1A · FBXW1A · IPI00307418 · FBW1A_HUMAN · BTRC · BTRCP)F-box/WD repeat-containing protein 1A⌘
H. sapiensENSEMBL:ENSG00000072803 · UniProtKB:Q9UKB1 (FBW1B_HUMAN · Q9UKB1 · FBXW1B · IPI00328796 · IPI00301283 · FBW1B · IPI00306671 · KIAA0696 · FBXW11 · BTRCP2)F-box/WD repeat-containing protein 11⌘
H. sapiensENSEMBL:ENSG00000109670 · UniProtKB:Q969H0 (IPI00059165 · FBXW7_HUMAN · Q969H0 · FBX30 · FBXW7 · SEL10 · IPI00402151 · FBW7 · IPI00056349 · IPI00075075)F-box/WD repeat-containing protein 7⌘
H. sapiensENSEMBL:ENSG00000007168 · UniProtKB:P43034 (MDS · LIS1_HUMAN · MDCR · PAFAH1B1 · PAFAHA · LIS1 · IPI00760905 · P43034 · IPI00218728)Platelet-activating factor acetylhydrolase IB subunit alpha⌘
M. musculusNCBI:NP_598776 · MGI:MGI:2144023 (Fbxw11 · BTRC2 · Fbxw1b · HOS · BTRCP2)F-box and WD-40 domain protein 11⌘
M. musculusNCBI:NP_001032847 · MGI:MGI:1338871 (Slimb · Beta-Trcp1 · Fbw1a · beta-TrCP · Btrc)SCF b-TRCP · beta-transducin repeat containing protein⌘
M. musculusUniProtKB:Q8VBV4 · MGI:MGI:1354695 (Fbxw6 · AGO · Fbxw7 · Fbw7 · SEL-10 · Cdc4 · Fbxo30)F-box and WD-40 domain protein 7⌘
M. musculusUniProtKB:P63005 · MGI:MGI:109520 (Mdsh · Lis1 · LIS-1 · Pafah1b1 · Pafaha)PAF-AH 45 · lissencephaly-1 protein · platelet-activating factor acetylhydrolase, isoform 1b, subunit 1⌘
R. norvegicusNCBI:XP_220281 · RGD:1309121 (Fbxw11)F-box and WD repeat domain containing 11⌘
R. norvegicusUniProtKB:P63004 · RGD:620331 (Pafah1b1)platelet-activating factor acetylhydrolase, isoform 1b, subunit 1⌘
R. norvegicusUniProtKB:Q5U4E5 · RGD:1359721 (Btrc)beta-transducin repeat containing⌘
S. cerevisiaeUniProtKB:P07834 · SGD:S000001885 (CDC4 · YFL009W)F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p⌘
S. cerevisiaeUniProtKB:P39014 · SGD:S000001308 (ZRG11 · YIL046W · MET30)F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex⌘
S. cerevisiaeUniProtKB:P39946 · SGD:S000005795 (YOR269W · PAC1)Protein involved in nuclear migration, part of the dynein/dynactin pathway⌘
S. pombeUniProtKB:Q09855 · GeneDB_Spombe:SPAC29E6.01 (SPAC29E6.01 · SPAC30.05 · pof11 · mug156)F-box protein Pof11⌘
S. pombeUniProtKB:P87053 · GeneDB_Spombe:SPAC57A10.05c (SPAC57A10.05c · pof1)F-box/WD repeat protein protein Pof1⌘
S. pombeUniProtKB:P87060 · GeneDB_Spombe:SPBC1718.01 (pop1 · SPBC2G2.18 · ste16 · SPBC1718.01)F-box/WD repeat protein Pop1⌘
S. pombeUniProtKB:O14170 · GeneDB_Spombe:SPAC4D7.03 (sud1 · SPAC4D7.03 · pop2)F-box/WD repeat protein Pop2⌘
ProteinPublicationCurator Notes
UniProtKB:P07834 · SGD:S000001885PMID:15814839 Atir-Lande A, et al. Role for the SCFCDC4 ubiquitin ligase in Candida albicans morphogenesis. Mol Biol Cell. 2005 Jun;16(6):2772-85.The C. albicans protein CaCDC4 complements a homologous mutation in S. cerevisiae. This paper shows that C. albicans CaCDC4 partially complements the S. cerevisiae cdc4 null mutant.
UniProtKB:P07834 · SGD:S000001885PMID:16228290 Shieh JC, et al. Identification and functional characterization of Candida albicans CDC4. J Biomed Sci. 2005 Dec;12(6):913-24.The C. albicans protein CaCDC4 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (2)
ENSEMBL:ENSG00000007168 · UniProtKB:P43034#247200 MILLER-DIEKER LISSENCEPHALY SYNDROME; MDLS;;MDSMILLER-DIEKER SYNDROME CHROMOSOME REGION, INCLUDED; MDCR, INCLUDED
UniProtKB:P39946 · SGD:S000005795#607432 LISSENCEPHALY 1; LIS1;;LISSENCEPHALY SEQUENCE, ISOLATED; ILS;;LISSENCEPHALY, CLASSICSUBCORTICAL LAMINAR HETEROTOPIA, INCLUDED; SCLH, INCLUDED;;SUBCORTICAL BAND HETEROTOPIA, INCLUDED; SBH, INCLUDED
SGD Disease Papers (2)
UniProtKB:P39946 · SGD:S000005795PMID:12566428 Lee WL, et al. (2003) The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast. J Cell Biol 160(3):355-64
PMID:12566423 Xiang X (2003) LIS1 at the microtubule plus end and its role in dynein-mediated nuclear migration. J Cell Biol 160(3):289-90
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