P-POD: Princeton Protein Orthology Database: GO3/Para1391

This family has 29 members: 4 Arabidopsis thaliana, 5 Caenorhabditis elegans, 4 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 2 Gallus gallus, 2 Homo sapiens, 2 Mus musculus, 4 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/Para1391
29 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_188365.1 · TAIR:locus:2089070 (MGD8.26 · AT3G17390 · MTO3 · SAMS3 · MAT4)S-ADENOSYLMETHIONINE SYNTHETASE · METHIONINE ADENOSYLTRANSFERASE 4 · S-ADENOSYLMETHIONINE SYNTHETASE 3 · METHIONINE OVER-ACCUMULATOR 3⌘
A. thalianaNCBI:NP_181225.1 · TAIR:locus:2058011 (T1J8_6 · T1J8.6 · MAT3 · AT2G36880)methionine adenosyltransferase 3⌘
A. thalianaNCBI:NP_171751.1 · TAIR:locus:2196160 (MAT1 · AT1G02500 · SAM1 · T14P4_17 · T14P4.17 · SAM-1)S-ADENOSYLMETHIONINE SYNTHETASE 1 · S-ADENOSYLMETHIONINE SYNTHETASE-1⌘
A. thalianaNCBI:NP_192094.1 · TAIR:locus:2141385 (T7B11_11 · MAT2 · T7B11.11 · SAM-2 · AT4G01850)S-ADENOSYLMETHIONINE SYNTHETASE 2⌘
C. elegansWB:WBGene00008205 (sams-1 · C49F5.1) · UniProtKB:O17680⌘
C. elegansWB:WBGene00015538 (sams-3 · C06E7.1) · UniProtKB:P50305⌘
C. elegansWB:WBGene00015540 (C06E7.3 · sams-4) · UniProtKB:P50306⌘
C. elegansWB:WBGene00006416 (sams-5 · T13A10.11) · UniProtKB:Q27522⌘
C. elegansWB:WBGene00013652 (sams-2 · Y105C5B.12) · UniProtKB:Q8I4F2⌘
D. rerioZFIN:ZDB-GENE-060421-5255 (zgc:136871) · UniProtKB:Q1RLT0⌘
D. rerioZFIN:ZDB-GENE-050327-6 (zgc:110847) · UniProtKB:Q58EF9⌘
D. rerioUniProtKB:Q7ZTW2 · ZFIN:ZDB-GENE-030131-2049 (mat2a)methionine adenosyltransferase II, alpha⌘
D. rerioUniProtKB:Q7ZW04 · ZFIN:ZDB-GENE-030131-6127 (mat1a)methionine adenosyltransferase I, alpha⌘
D. discoideumUniProtKB:Q54F07 · dictyBase:DDB_G0291179 (metK · SAMS · MAT)S-adenosylmethionine synthetase⌘
D. melanogasterUniProtKB:P40320 · FB:FBgn0005278 (M(2)21AB · Sam-S · METK · SamS · Su(z)5 · CG2674 · m(2)21ab · M(2)21A-B)S-Adenosylmethionine synthetase · S-adenosylmethionine synthetase · Minute (2) 21AB · Methionine adenosyl transferase⌘
E. coliUniProtKB:P0A817 · ECOLI:S-ADENMETSYN-MONOMER (metK · MetK · b2942 · ECK2937 · metX)methionine adenosyltransferase⌘
G. gallusNCBI:XP_421512 · ENTREZ:423628
G. gallusNCBI:XP_424874 · ENTREZ:427292
H. sapiensENSEMBL:ENSG00000151224 · UniProtKB:Q00266 (IPI00021772 · Q00266 · AMS1 · METK1_HUMAN · MATA1 · MAT1A)S-adenosylmethionine synthetase isoform type-1⌘
H. sapiensENSEMBL:ENSG00000168906 · UniProtKB:P31153 (METK2_HUMAN · MATA2 · MAT2A · IPI00010157 · AMS2 · P31153)S-adenosylmethionine synthetase isoform type-2⌘
M. musculusUniProtKB:Q91X83 · MGI:MGI:88017 (SAMS1 · AdoMet · Mat1a · SAMS · Ams · MAT · MATA1)methionine adenosyltransferase I, alpha⌘
M. musculusUniProtKB:Q3THS6 · MGI:MGI:2443731 (Mat2a)methionine adenosyltransferase II, alpha⌘
R. norvegicusNCBI:XP_573428 · RGD:1560523 (RGD1560523)similar to S-adenosylmethionine synthetase gamma form (Methionine adenosyltransferase)⌘
R. norvegicusNCBI:XP_001065243 · RGD:1589200
R. norvegicusUniProtKB:P13444 · RGD:3050 (Mat1a)methionine adenosyltransferase I, alpha⌘
R. norvegicusUniProtKB:P18298 · RGD:619985 (Mat2a)methionine adenosyltransferase II, alpha⌘
S. cerevisiaeUniProtKB:P10659 · SGD:S000004170 (ETH10 · YLR180W · SAM1)S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine⌘
S. cerevisiaeUniProtKB:P19358 · SGD:S000002910 (SAM2 · ETH2 · YDR502C)S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine⌘
S. pombeUniProtKB:O60198 · GeneDB_Spombe:SPBC14F5.05c (sam1 · SPBC14F5.05c)S-adenosylmethionine synthetase⌘
ProteinPublicationCurator Notes
UniProtKB:P19358 · SGD:S000002910PMID:12192860 Li DY, et al. [Production of SAM by recombinant Pichia pastoris]. Sheng Wu Gong Cheng Xue Bao. 2002 May;18(3):295-9.The S. cerevisiae protein SAM2 was expressed in P. pastoris, but complementation was not directly tested. The article is in Chinese and therefore the curation was based on the abstract alone.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
UniProtKB:P10659 · SGD:S000004170#250850 METHIONINE ADENOSYLTRANSFERASE DEFICIENCY;;MAT DEFICIENCY;;MAT I/III DEFICIENCY;;HYPERMETHIONINEMIA, ISOLATED PERSISTENT
SGD Disease Papers (2)
UniProtKB:P19358 · SGD:S000002910PMID:9300813 Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10
UniProtKB:P19358 · SGD:S000002910PMID:9300813 Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10
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