This family has 66 members: 7 Arabidopsis thaliana, 3 Caenorhabditis elegans, 8 Danio rerio, 3 Dictyostelium discoideum, 14 Drosophila melanogaster, 4 Gallus gallus, 8 Homo sapiens, 8 Mus musculus, 8 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
Interactive Java Applets: Notung Tree Analysis · Jalview Alignment
| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | NCBI:NP_190979.1 · TAIR:locus:2080300 (ATUCP1 · ATPUMP1 · UCP1 · AT3G54110 · F24B22.70 · PUMP1 · UCP) | ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 · UNCOUPLING PROTEIN 1 · PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 · ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 |  |
| A. thaliana | NCBI:NP_196509.1 · TAIR:locus:2184832 (AT5G09470 · T5E8_270 · T5E8.270) | | |
| A. thaliana | NCBI:NP_568894.1 · TAIR:locus:2154593 (AT5G58970 · K19M22_21 · K19M22.21 · ATUCP2) | UNCOUPLING PROTEIN 2 | |
| A. thaliana | NCBI:NP_194188.1 · TAIR:locus:2121974 (F22K18.230 · AT4G24570 · F22K18_230) | | |
| A. thaliana | NCBI:NP_179836.1 · TAIR:locus:2041183 (F14M13.10 · F14M13_10 · UCP5 · AT2G22500 · ATPUMP5) | PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 5 · UNCOUPLING PROTEIN 5 | |
| A. thaliana | NCBI:NP_197477.1 · TAIR:locus:2183254 (AT5G19760 · T29J13_180 · T29J13.180) | | |
| A. thaliana | NCBI:NP_172866.1 · TAIR:locus:2035769 (AT1G14140 · F7A19_22 · F7A19.22) | | |
| C. elegans | WB:WBGene00006729 (K07B1.3 · ucp-4) · UniProtKB:O01883 | | |
| C. elegans | WB:WBGene00015186 (misc-1 · B0432.4) · UniProtKB:P90992 | | |
| C. elegans | WB:WBGene00019656 (K11G12.5) · UniProtKB:Q27322 | | |
| D. rerio | ENSEMBL:ENSDARP00000003308 | ||
| D. rerio | ENSEMBL:ENSDARP00000051848 | ||
| D. rerio | UniProtKB:Q9W720 · ZFIN:ZDB-GENE-990708-8 (ucp2) | uncoupling protein 2 | |
| D. rerio | UniProtKB:Q7ZVP4 · ZFIN:ZDB-GENE-010503-1 (ucp4) | uncoupling protein 4 | |
| D. rerio | UniProtKB:Q7ZVV6 · ZFIN:ZDB-GENE-040426-749 (slc25a14) | solute carrier family 25 (mitochondrial carrier, brain), member 14 | |
| D. rerio | UniProtKB:Q7ZWA7 · ZFIN:ZDB-GENE-040426-1095 (slc25a10) | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | |
| D. rerio | UniProtKB:A8KC25 · ZFIN:ZDB-GENE-040426-1317 (ucp2l) | uncoupling protein 2, like | |
| D. rerio | UniProtKB:Q7T3F5 · ZFIN:ZDB-GENE-040426-1290 (slc25a27) | solute carrier family 25, member 27 | |
| D. discoideum | NCBI:EDR41064.1 · dictyBase:DDB_G0283333 (ucpB) | mitochondrial substrate carrier family protein | |
| D. discoideum | UniProtKB:Q54PY7 · dictyBase:DDB_G0284225 (slc25a11 · ucpC) | mitochondrial 2-oxoglutarate/malate carrier protein, mitochondrial brown fat uncoupling family protein, mitochondrial substrate carrier family protein | |
| D. discoideum | UniProtKB:Q55BF4 · dictyBase:DDB_G0271310 (ucpA · slc25a35) | mitochondrial substrate carrier family protein, putative mitochondrial oxaloacetate transporter, transmembrane protein | |
| D. melanogaster | FB:FBgn0033248 (CG11196) · UniProtKB:A1Z787 | | |
| D. melanogaster | FB:FBgn0033904 (CG18327) · UniProtKB:A1Z9L9 | | |
| D. melanogaster | FB:FBgn0033905 (CG18324) · UniProtKB:A1Z9M0 | | |
| D. melanogaster | FB:FBgn0033903 (CG8323) · UniProtKB:Q7JZE8 | | |
| D. melanogaster | FB:FBgn0036199 (CG7314 · ucp5 · UCP5 · DmUCP5 · DmBMCP · dmUCP5 · Bmcp) · UniProtKB:Q7K566 | | |
| D. melanogaster | FB:FBgn0039674 (CG1907) · UniProtKB:Q9VAJ9 | | |
| D. melanogaster | FB:FBgn0038797 (CG4323) · UniProtKB:Q9VDM3 | | |
| D. melanogaster | FB:FBgn0031758 (Ucp4B · dmUCP4b · DmUCP4B · CG18340) · UniProtKB:Q9VMK0 | | |
| D. melanogaster | FB:FBgn0031757 (anon-WO03061681.2 · anon-WO0242455.3 · DmUCP4C · anon-WO02079478.1 · anon-WO0242455.4 · CG9064 · anon-WO02079478.2 · anon-WO03037362.7 · anon-WO03061681.1 · Ucp4C · dmUCP4c) · UniProtKB:Q9VMK1 | | |
| D. melanogaster | FB:FBgn0036808 (CG18363) · UniProtKB:Q9VVS1 | | |
| D. melanogaster | FB:FBgn0030872 (DmUCP4A · UCP4A · dmUCP4a · Ucp4A · Ucp4a · CG6492) · UniProtKB:Q9VX14 | | |
| D. melanogaster | FB:FBgn0035568 (anon-WO0140519.190 · CG18418) · UniProtKB:Q9VZ93 | | |
| D. melanogaster | FB:FBgn0035567 (CG7514) · UniProtKB:Q9VZ94 | | |
| D. melanogaster | FB:FBgn0027610 (BcDNA:GH02431 · CG8790) · UniProtKB:Q9Y166 | | |
| G. gallus | NCBI:XP_417040 · ENTREZ:418845 | ||
| G. gallus | NCBI:XP_001232238 · ENTREZ:769048 | ||
| G. gallus | UniProtKB:Q5ZJX8 (IPI00818205 · RCJMB04_14i19 · Q5ZJX8) · ENTREZ:422141 | | |
| G. gallus | UniProtKB:Q9DDT7 · ENTREZ:373896 | ||
| H. sapiens | ENSEMBL:ENSG00000183048 · UniProtKB:Q9UBX3 (Q9UBX3 · DIC_HUMAN · IPI00217277 · SLC25A10 · IPI00015920 · DIC) | Mitochondrial dicarboxylate carrier | |
| H. sapiens | ENSEMBL:ENSG00000174032 · UniProtKB:Q5SVS4 (IPI00179034 · KMCP1 · Q5SVS4 · KMCP1_HUMAN · SLC25A30) | Kidney mitochondrial carrier protein 1 | |
| H. sapiens | ENSEMBL:ENSG00000108528 · UniProtKB:Q02978 (IPI00219729 · SLC25A11 · Q02978 · SLC20A4 · M2OM_HUMAN) | Mitochondrial 2-oxoglutarate/malate carrier protein | |
| H. sapiens | ENSEMBL:ENSG00000125434 · UniProtKB:Q3KQZ1 (IPI00654813 · IPI00167392 · Q3KQZ1 · S2535_HUMAN · IPI00847815 · IPI00432939 · SLC25A35) | Solute carrier family 25 member 35 | |
| H. sapiens | ENSEMBL:ENSG00000175567 · UniProtKB:P55851 (UCP2_HUMAN · SLC25A8 · IPI00026573 · UCP2 · P55851) | Mitochondrial uncoupling protein 2 | |
| H. sapiens | ENSEMBL:ENSG00000175564 · UniProtKB:P55916 (UCP3_HUMAN · UCP3 · IPI00221048 · SLC25A9 · IPI00221047 · IPI00026815 · P55916) | Mitochondrial uncoupling protein 3 | |
| H. sapiens | ENSEMBL:ENSG00000153291 · UniProtKB:O95847 (UCP4_HUMAN · UCP4 · O95847 · IPI00383871 · UNQ772/PRO1566 · SLC25A27) | Mitochondrial uncoupling protein 4 | |
| H. sapiens | ENSEMBL:ENSG00000102078 · UniProtKB:O95258 (IPI00221084 · UCP5_HUMAN · IPI00010162 · IPI00029460 · UCP5 · O95258 · UNQ791/PRO1682 · BMCP1 · SLC25A14) | Brain mitochondrial carrier protein 1 | |
| M. musculus | NCBI:NP_082987 · MGI:MGI:1921261 (Slc25a27 · Ucp4) | solute carrier family 25, member 27 | |
| M. musculus | UniProtKB:Q9QZD8 · MGI:MGI:1353497 (Dic · Slc25a10) | solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 | |
| M. musculus | UniProtKB:Q9CR58 · MGI:MGI:1914804 (KMCP1 · Slc25a30) | solute carrier family 25, member 30 | |
| M. musculus | UniProtKB:Q9CR62 · MGI:MGI:1915113 (Slc25a11 · 2oxoc) | solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 | |
| M. musculus | UniProtKB:Q5SWT3 · MGI:MGI:1919248 (Slc25a35) | solute carrier family 25, member 35 | |
| M. musculus | UniProtKB:P70406 · MGI:MGI:109354 (Ucp2) | uncoupling protein 2 (mitochondrial, proton carrier) | |
| M. musculus | UniProtKB:P56501 · MGI:MGI:1099787 (Ucp3 · UCP-3 · Slc25a9) | uncoupling protein 3 (mitochondrial, proton carrier) | |
| M. musculus | UniProtKB:Q9Z2B2 · MGI:MGI:1330823 (UCP5S · Slc25a14 · UCP5L · UCP5 · BMCP1) | solute carrier family 25 (mitochondrial carrier, brain), member 14 | |
| R. norvegicus | NCBI:XP_001078825 · RGD:1598229 (Slc25a35) | solute carrier family 25, member 35 | |
| R. norvegicus | UniProtKB:Q5PQM9 · RGD:1359702 (Slc25a30) | solute carrier family 25, member 30 | |
| R. norvegicus | UniProtKB:P97700 · RGD:708476 (Slc25a11) | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | |
| R. norvegicus | UniProtKB:P56500 · RGD:3932 (Ucp2) | uncoupling protein 2 (mitochondrial, proton carrier) | |
| R. norvegicus | UniProtKB:P56499 · RGD:3933 (Ucp3) | uncoupling protein 3 (mitochondrial, proton carrier) | |
| R. norvegicus | UniProtKB:O89035 · RGD:621430 (Slc25a10) | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | |
| R. norvegicus | UniProtKB:Q9EP88 · RGD:621433 (Slc25a14) | solute carrier family 25 (mitochondrial carrier, brain), member 14 | |
| R. norvegicus | UniProtKB:Q9EPH5 · RGD:620787 (Slc25a27) | solute carrier family 25, member 27 | |
| S. cerevisiae | UniProtKB:Q06143 · SGD:S000004340 (DIC1 · YLR348C) | Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix | |
| S. cerevisiae | UniProtKB:P32332 · SGD:S000001603 (YKL120W · OAC1) | Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate | |
| S. pombe | UniProtKB:Q9UTN1 · GeneDB_Spombe:SPAC139.02c (oac1 · SPAC139.02c) | mitochondrial anion transporter | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| OMIM (2) | |
|---|---|
| ENSEMBL:ENSG00000175564 · UniProtKB:P55916 | #607447 BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 4; BMIQ4;;OBESITY, SUSCEPTIBILITY TO |
| ENSEMBL:ENSG00000175564 · UniProtKB:P55916 | #601665 OBESITYLEANNESS, INCLUDED |