P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL942

This family has 18 members: 1 Arabidopsis thaliana, 1 Caenorhabditis elegans, 2 Danio rerio, 2 Dictyostelium discoideum, 2 Drosophila melanogaster, 1 Gallus gallus, 2 Homo sapiens, 2 Mus musculus, 2 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/OrthoMCL942
18 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_193885.2 · TAIR:locus:2119642 (F18E5_160 · SPHK1 · F18E5.160 · AT4G21540)SPHINGOSINE KINASE 1⌘
C. elegansWB:WBGene00007918 (C34C6.5 · sphk-1) · UniProtKB:Q18425⌘
D. rerioENSEMBL:ENSDARP00000078472
D. rerioENSEMBL:ENSDARP00000078469
D. discoideumUniProtKB:Q86KF9 · dictyBase:DDB_G0272522 (sgkA · SPHK · SK)sphingosine kinase⌘
D. discoideumUniProtKB:Q6B516 · dictyBase:DDB_G0284545 (SPHK · SK · sgkB)sphingosine kinase⌘
D. melanogasterUniProtKB:Q9VYY8 · FB:FBgn0030300 (CG1747 · Sphk1 · Sk1 · SK1)Sphingosine kinase 1 · Sphingosine kinase I⌘
D. melanogasterUniProtKB:Q9VZW0 · FB:FBgn0052484 (Sk2 · Sphk2 · SK2 · CG32484 · CG2159)sphingosine kinase 2 · Sphingosine kinase II · sphingosine kinase · Sphingosine kinase 2⌘
G. gallusNCBI:XP_425374 · ENTREZ:427803
H. sapiensENSEMBL:ENSG00000176170 · UniProtKB:Q9NYA1 (SPK · Q9NYA1 · SPHK1 · SPHK1_HUMAN · IPI00790290 · SPHK · IPI00182048)Sphingosine kinase 1⌘
H. sapiensENSEMBL:ENSG00000063176 · UniProtKB:Q9NRA0 (SPHK2_HUMAN · IPI00215796 · IPI00024496 · Q9NRA0 · IPI00215795 · SPHK2)Sphingosine kinase 2⌘
M. musculusUniProtKB:Q8CI15 · MGI:MGI:1316649 (Sphk1 · SK1)sphingosine kinase 1⌘
M. musculusUniProtKB:Q9JIA7 · MGI:MGI:1861380 (SPHK2_MOUSE · IPI00310333 · Sphk2)sphingosine kinase 2⌘
R. norvegicusUniProtKB:Q91V26 · RGD:620048 (Sphk1)sphingosine kinase 1⌘
R. norvegicusUniProtKB:Q6AYB2 · RGD:1307757 (Sphk2)sphingosine kinase 2⌘
S. cerevisiaeUniProtKB:Q12246 · SGD:S000005697 (YOR171C · LCB4)Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes⌘
S. cerevisiaeUniProtKB:Q06147 · SGD:S000004250 (LCB5 · YLR260W)Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules⌘
S. pombeUniProtKB:O14159 · GeneDB_Spombe:SPAC4A8.07c (SPAC4A8.07c)sphingoid long chain base kinase⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu