P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL6127

This family has 7 members: 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 2 Saccharomyces cerevisiae, 2 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/OrthoMCL6127
7 members.
OrganismProtein (Synonyms)DescriptionAmiGO
H. sapiensENSEMBL:ENSG00000169174 · UniProtKB:Q8NBP7 (IPI00387168 · NARC1 · Q8NBP7 · PCSK9_HUMAN · PSEC0052 · PCSK9 · IPI00387169)Proprotein convertase subtilisin/kexin type 9⌘
M. musculusUniProtKB:Q80W65 · MGI:MGI:2140260 (IPI00377933 · Narc1 · Pcsk9 · PCSK9_MOUSE)proprotein convertase subtilisin/kexin type 9⌘
R. norvegicusUniProtKB:P59996 · RGD:728909 (Pcsk9)proprotein convertase subtilisin/kexin type 9⌘
S. cerevisiaeUniProtKB:P09232 · SGD:S000000786 (PRB1 · YEL060C · CVT1)Vacuolar proteinase B (yscB), a serine protease of the subtilisin family⌘
S. cerevisiaeUniProtKB:P25036 · SGD:S000005529 (YOR003W · YSP3)Putative precursor to the subtilisin-like protease III⌘
S. pombeUniProtKB:P40903 · GeneDB_Spombe:SPAC4A8.04 (prb1 · SPAC4A8.04 · isp6)vacuolar serine protease Isp6⌘
S. pombeUniProtKB:Q9UTS0 · GeneDB_Spombe:SPAC1006.01 (SPAC1006.01 · psp3)serine protease Psp3⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (2)
ENSEMBL:ENSG00000169174 · UniProtKB:Q8NBP7#603776 HYPERCHOLESTEROLEMIA, AUTOSOMAL DOMINANT, 3; HCHOLA3;;FH3
UniProtKB:P09232 · SGD:S000000786+607786 PROPROTEIN CONVERTASE, SUBTILISIN/KEXIN-TYPE, 9; PCSK9;;NEURAL APOPTOSIS-REGULATED CONVERTASE 1; NARC1LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS1, INCLUDED; LDLCQ1, INCLUDED
SGD Disease Papers (1)
UniProtKB:P09232 · SGD:S000000786PMID:12923060 Roberts BT and Wickner RB (2003) Heritable activity: a prion that propagates by covalent autoactivation. Genes Dev 17(17):2083-7
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