P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL4716

This family has 9 members: 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

9 members.
OrganismProtein (Synonyms)DescriptionAmiGO
D. rerioZFIN:ZDB-GENE-060825-144 (zgc:154081) · UniProtKB:Q0P3U2⌘
D. discoideumUniProtKB:Q54DX3 · dictyBase:DDB_G0291926 (DDB_G0291926)endothelial monocyte-activating polypeptide II precursor pro-EMAP II family protein⌘
D. melanogasterUniProtKB:A1Z7K8 · FB:FBgn0033351 (CG8235)⌘
G. gallusNCBI:XP_420496 · ENTREZ:422533
H. sapiensENSEMBL:ENSG00000164022 · UniProtKB:Q12904 (EMAP2 · MCA1_HUMAN · Q12904 · SCYE1 · IPI00006252)Multisynthetase complex auxiliary component p43⌘
M. musculusUniProtKB:P31230 · MGI:MGI:102774 (Emap2 · p43 · Scye1 · AIMP1)small inducible cytokine subfamily E, member 1⌘
R. norvegicusUniProtKB:Q4G079 · RGD:620466 (Scye1)small inducible cytokine subfamily E, member 1⌘
S. cerevisiaeUniProtKB:P46672 · SGD:S000003073 (YGL105W · ARC1)Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm⌘
S. pombeUniProtKB:Q9P6K7 · GeneDB_Spombe:SPAC30C2.04 (SPAC30C2.04)cofactor for methionyl-and glutamyl-tRNA synthetases⌘
ProteinPublicationCurator Notes
UniProtKB:P46672 · SGD:S000003073PMID:15184019 Golinelli-Cohen MP, et al. Complementation of yeast Arc1p by the p43 component of the human multisynthetase complex does not require its association with yeast MetRS and GluRS. J Mol Biol. 2004 Jun 25;340(1):15-27.The O. sativa protein OsMetRS was expressed in S. cerevisiae, but complementation was not directly tested. Rice MetRS complements a yeast arc1 mes1 double mutant, but is only homologous to MES1.
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
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