P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL3024

This family has 11 members: 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/OrthoMCL3024
11 members.
OrganismProtein (Synonyms)DescriptionAmiGO
C. elegansWB:WBGene00004680 (rrt-2 · C29H12.1) · UniProtKB:Q18316⌘
D. rerioUniProtKB:Q6PGW8 · ZFIN:ZDB-GENE-040426-1244 (rars2)arginyl-tRNA synthetase 2, mitochondrial (putative)⌘
D. discoideumUniProtKB:Q558Z0 · dictyBase:DDB_G0272867 (ArgRS · argS · argS1)arginyl-tRNA synthetase, arginine-tRNA ligase⌘
D. melanogasterUniProtKB:Q8SXK2 · FB:FBgn0037526 (CG10092 · atl)arginyl tRNA ligase⌘
G. gallusNCBI:XP_419847 · ENTREZ:421823
H. sapiensENSEMBL:ENSG00000146282 · UniProtKB:Q5T160 (IPI00549566 · Q5T160 · RARSL · RARS2 · SYRM_HUMAN)Probable arginyl-tRNA synthetase, mitochondrial⌘
M. musculusUniProtKB:Q3U186 · MGI:MGI:1923596 (PRO1992 · Rarsl · Rars2)arginyl-tRNA synthetase 2, mitochondrial⌘
R. norvegicusNCBI:XP_001065097 · RGD:1305419 (Rars2)arginyl-tRNA synthetase 2, mitochondrial⌘
S. cerevisiaeUniProtKB:Q05506 · SGD:S000002749 (RRS1 · YDR341C)Arginyl-tRNA synthetase, proposed to be cytoplasmic but the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies⌘
S. cerevisiaeUniProtKB:P38714 · SGD:S000001133 (YHR091C · MSR1)Mitochondrial arginyl-tRNA synthetase⌘
S. pombeUniProtKB:O74781 · GeneDB_Spombe:SPBC25B2.09c (mrs1 · SPBC25B2.09c · rrs1)mitochondrial and cytoplasmic arginine-tRNA ligase Rrs1/Mrs1⌘
ProteinPublicationCurator Notes
UniProtKB:P38714 · SGD:S000001133PMID:22569581 Cassandrini D, et al. Pontocerebellar hypoplasia type 6 caused by mutations in RARS2: definition of the clinical spectrum and molecular findings in five patients. J Inherit Metab Dis. 2013 Jan;36(1):43-53.The H. sapiens protein RARS2 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000146282 · UniProtKB:Q5T160#611523 PONTOCEREBELLAR HYPOPLASIA TYPE 6; PCH6;;ENCEPHALOPATHY, FATAL INFANTILE, WITH MITOCHONDRIAL RESPIRATORY CHAINDEFECTS
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