This family has 11 members: 1 Arabidopsis thaliana, 1 Drosophila melanogaster, 7 Saccharomyces cerevisiae, 2 Schizosaccharomyces pombe.
Interactive Java Applets: Notung Tree Analysis · Jalview Alignment
| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | TAIR:locus:2033258 (F4N2.8 · AT1G69100 · F4N2_8) · NCBI:NP_177073.2 |  | |
| D. melanogaster | FB:FBgn0038506 (CG5860 · FBgn0038506) · UniProtKB:Q9VEK4 | | |
| S. cerevisiae | UniProtKB:P12630 · SGD:S000001277 (YIL015W · SST1 · BAR1) | Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest | |
| S. cerevisiae | UniProtKB:P53379 · SGD:S000002551 (YPS2 · MKC7 · YDR144C) | GPI-anchored aspartyl protease (yapsin) involved in protein processing | |
| S. cerevisiae | UniProtKB:Q3E740 · SGD:S000007607 (YGL258W-A) | Putative protein of unknown function | |
| S. cerevisiae | UniProtKB:P53057 · SGD:S000003228 (YGL259W · YPS5) | Protein with similarity to GPI-anchored aspartic proteases such as Yap1p and Yap3p | |
| S. cerevisiae | UniProtKB:P32329 · SGD:S000004110 (YLR120C · YAP3 · YPS1) | Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor | |
| S. cerevisiae | UniProtKB:Q12303 · SGD:S000004111 (YPS3 · YPS4 · YLR121C) | Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor | |
| S. cerevisiae | UniProtKB:P40583 · SGD:S000001478 (YIR039C · YPS6) | Putative GPI-anchored aspartic protease | |
| S. pombe | UniProtKB:P32834 · GeneDB_Spombe:SPAC26A3.01 (sxa1 · SPAC26A3.01 · SPAC2E1P5.06) | aspartic protease Sxa1 | |
| S. pombe | UniProtKB:O59774 · GeneDB_Spombe:SPCC1795.09 (SPCC1795.09 · yps1) | aspartic protease Yps1 | |
| Protein | Publication | Curator Notes | |
|---|---|---|---|
| UniProtKB:P32329 · SGD:S000004110 |  16087741 Krysan DJ, et al. Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae. Eukaryot Cell. 2005 Aug;4(8):1364-74. | The C. albicans protein SAP9 complements a homologous mutation in S. cerevisiae. | |
| UniProtKB:P32329 · SGD:S000004110 | 16087741 Krysan DJ, et al. Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae. Eukaryot Cell. 2005 Aug;4(8):1364-74. | The C. glabrata protein CgYPS1 complements a homologous mutation in S. cerevisiae. |
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| SGD Disease Papers (1) | |
|---|---|
| UniProtKB:P12630 · SGD:S000001277 | 15077905 Bousquet C, et al. (2004) Somatostatin receptors and regulation of cell proliferation. Dig Liver Dis 36 Suppl 1:S2-7 |