P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL2234

This family has 12 members: 2 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

12 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_198095.1 · TAIR:locus:2146345 (F21A20_140 · F21A20.140 · AT5G27430)⌘
A. thalianaNCBI:NP_566250.1 · TAIR:locus:2096229 (AT3G05230 · T12H1_20 · T12H1.20)⌘
C. elegansWB:WBGene00019679 (K12H4.4) · UniProtKB:P34525⌘
D. rerioUniProtKB:Q6NWJ2 · ZFIN:ZDB-GENE-040426-2206 (spcs3)signal peptidase complex subunit 3 homolog (S. cerevisiae)⌘
D. discoideumUniProtKB:B0G180 · dictyBase:DDB_G0290851 (spc3)microsomal signal peptidase subunit, signal peptidase complex subunit 3⌘
D. melanogasterUniProtKB:Q9VCA9 · FB:FBgn0039172 (CG5677 · Spase22/23 · Spase22-23)Spase 22/23-subunit⌘
G. gallusENTREZ:396234 · UniProtKB:P28687 (SPC22 · P28687 · SPCS3_CHICK · IPI00600134)Signal peptidase complex subunit 3⌘
H. sapiensENSEMBL:ENSG00000129128 · UniProtKB:P61009 (SPCS3 · P61009 · IPI00300299 · SPCS3_HUMAN · SPC22 · UNQ1841/PRO3567)Signal peptidase complex subunit 3⌘
M. musculusNCBI:NP_083977 · MGI:MGI:1923937
R. norvegicusNCBI:XP_001058844 · RGD:1588184
S. cerevisiaeUniProtKB:Q12133 · SGD:S000004056 (SPC3 · YLR066W)Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway⌘
S. pombeUniProtKB:Q10259 · GeneDB_Spombe:SPAC56F8.11 (SPAC56F8.11 · spc3)signal peptidase subunit Spc3⌘
ProteinPublicationCurator Notes
UniProtKB:Q12133 · SGD:S000004056PMID:15300682 De La Rosa JM, et al. Characterization of Candida albicans orthologue of the Saccharomyces cerevisiae signal-peptidase-subunit encoding gene SPC3. Yeast. 2004 Jul 30;21(10):883-94.The C. albicans protein SPC3 complements a homologous mutation in S. cerevisiae.
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu