P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL2225

This family has 12 members: 2 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/OrthoMCL2225
12 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2016354 (F19K16_10 · AT1G79940 · F19K16.10 · ATERDJ2A) · NCBI:NP_178112.2⌘
A. thalianaNCBI:NP_567621.1 · TAIR:locus:2127373 (ATERDJ2B · AT4G21180 · F7J7.120 · F7J7_120)⌘
C. elegansWB:WBGene00001047 (dnj-29 · Y63D3A.6) · UniProtKB:Q9U1V9⌘
D. rerioUniProtKB:Q6DGY6 · ZFIN:ZDB-GENE-040718-328 (sec63)SEC63-like (S. cerevisiae)⌘
D. discoideumdictyBase:DDB_G0286131 (DDB_G0286131) · UniProtKB:Q54M91⌘
D. melanogasterFB:FBgn0035771 (peg · anon-WO0118547.333 · CG8583 · sec63) · UniProtKB:Q9VS57⌘
G. gallusNCBI:XP_419802 · ENTREZ:421774
H. sapiensENSEMBL:ENSG00000025796 · UniProtKB:Q9UGP8 (Q9UGP8 · IPI00218922 · SEC63_HUMAN · SEC63 · SEC63L)Translocation protein SEC63 homolog⌘
M. musculusUniProtKB:Q8VHE0 · MGI:MGI:2155302 (Sec63)SEC63-like (S. cerevisiae)⌘
R. norvegicusNCBI:NP_001101107 · RGD:1304984
S. cerevisiaeUniProtKB:P14906 · SGD:S000005780 (SEC63 · PTL1 · YOR254C)Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p)⌘
S. pombeUniProtKB:Q9HGN7 · GeneDB_Spombe:SPBC36B7.03 (sec63 · SPBC36B7.03)ER protein translocation subcomplex subunit Sec63⌘
ProteinPublicationCurator Notes
UniProtKB:P14906 · SGD:S000005780PMID:16889384 Zhang W, et al. Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins. Biotechnol Prog. 2006 Jul-Aug;22(4):1090-5.The S. cerevisiae protein SEC63 was expressed in P. pastoris, but complementation was not directly tested. This paper shows heterologous overexpression of S. cerevisiae SEC63 in P. pastoris.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000025796 · UniProtKB:Q9UGP8#174050 POLYCYSTIC LIVER DISEASE; PCLD
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