P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL1893

This family has 13 members: 2 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/OrthoMCL1893
13 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_201145.1 · TAIR:locus:2167316 (ADK1 · MLE2_3 · MLE2.3 · AT5G63400)ADENYLATE KINASE 1⌘
A. thalianaNCBI:NP_199848.1 · TAIR:locus:2177527 (MXI22_8 · MXI22.8 · AT5G50370)⌘
C. elegansUniProtKB:P34346 · WB:WBGene00002879 (C29E4.8 · let-754)⌘
D. rerioUniProtKB:Q7T3D7 · ZFIN:ZDB-GENE-030131-512 (ak2)adenylate kinase 2⌘
D. discoideumUniProtKB:Q54QJ9 · dictyBase:DDB_G0283805 (adkA · ADK)adenylate kinase⌘
D. melanogasterUniProtKB:Q9U915 · FB:FBgn0022708 (Adk2 · anon-Dak2 · BcDNA:SD09634 · Dak2 · CG3140 · ADK-2)Adenylate kinase-2⌘
E. coliUniProtKB:P69441 · ECOLI:ADENYL-KIN-MONOMER (ECK0468 · Adk · plsA · b0474 · dnaW · adk)adenylate kinase⌘
G. gallusNCBI:XP_425786 · ENTREZ:428227
H. sapiensENSEMBL:ENSG00000004455 · UniProtKB:P54819 (IPI00218989 · IPI00172460 · IPI00218988 · KAD2_HUMAN · IPI00215901 · P54819 · AK2 · ADK2)Adenylate kinase 2, mitochondrial⌘
M. musculusUniProtKB:Q9WTP6 · MGI:MGI:87978 (Ak2 · D4Ertd220e · Ak-2)adenylate kinase 2⌘
R. norvegicusRGD:2077 (Ak2) · UniProtKB:P29410 (KAD2_RAT · IPI00230857 · Ak2 · IPI00923141 · P29410)adenylate kinase 2 · Adenylate kinase 2, mitochondrial⌘⌘
S. cerevisiaeUniProtKB:P07170 · SGD:S000002634 (ADK1 · AKY1 · AKY2 · YDR226W)Adenylate kinase, required for purine metabolism⌘
S. pombeUniProtKB:P33075 · GeneDB_Spombe:SPAC4G9.03 (SPAC4G9.03 · adk1)adenylate kinase Adk1⌘
ProteinPublicationCurator Notes
UniProtKB:P07170 · SGD:S000002634PMID:8439550 Konrad M. Identification and characterization of a yeast gene encoding an adenylate kinase homolog. Biochim Biophys Acta. 1993 Feb 20;1172(1-2):12-6.The S. cerevisiae protein ADK1 was expressed in E. coli, but complementation was not directly tested.
UniProtKB:P07170 · SGD:S000002634PMID:18433446 Gauthier S, et al. Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Mol Microbiol. 2008 Jun;68(6):1583-94.The H. sapiens protein AK1 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000004455 · UniProtKB:P54819%267500 RETICULAR DYSGENESIA;;RETICULAR DYSGENESIS;;CONGENITAL ALEUKIA;;SEVERE COMBINED IMMUNODEFICIENCY WITH LEUKOPENIA;;DE VAAL DISEASE;;HEMATOPOIETIC HYPOPLASIA, GENERALIZED
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