P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL1869

This family has 13 members: 2 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

13 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2161670 (MCO15_2 · MCO15.2 · AT5G55070) · NCBI:NP_200318.1⌘
A. thalianaNCBI:NP_567761.1 · TAIR:locus:2116432 (F10M23.250 · F10M23_250 · AT4G26910)⌘
C. elegansWB:WBGene00020950 (W02F12.5) · UniProtKB:O45148⌘
D. rerioUniProtKB:Q7ZVL3 · ZFIN:ZDB-GENE-030326-1 (dlst)dihydrolipoamide S-succinyltransferase⌘
D. discoideumUniProtKB:Q869Y7 · dictyBase:DDB_G0275029 (DLST · odhB)dihydrolipoamide S-succinyltransferase, 2-oxoglutarate dehydrogenase E2 component, dihydrolipoyllysine-residue succinyltransferase⌘
D. melanogasterFB:FBgn0037891 (CG5214) · UniProtKB:Q9VGQ1⌘
E. coliUniProtKB:P0AFG6 · ECOLI:SUCB-LIPOATE (SucB · B0727 · SucB-lipoate)⌘
G. gallusUniProtKB:Q5F326 (RCJMB04_39i8 · IPI00592325 · Q5F326) · ENTREZ:423357⌘
H. sapiensENSEMBL:ENSG00000119689 · UniProtKB:P36957 (DLST · P36957 · DLTS · ODO2_HUMAN · IPI00420108)Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial⌘
M. musculusUniProtKB:Q9D2G2 · MGI:MGI:1926170 (Dlst)dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)⌘
R. norvegicusUniProtKB:Q01205 · RGD:1359615 (Dlst)dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)⌘
S. cerevisiaeUniProtKB:P19262 · SGD:S000002555 (YDR148C · KGD2)Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle⌘
S. pombeUniProtKB:O94681 · GeneDB_Spombe:SPBC776.15c (SPBC776.15c)dihydrolipoamide S-succinyltransferase, e2 component of oxoglutarate dehydrogenase complex⌘

No functional conservation results.

Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
SGD Disease Papers (1)
UniProtKB:P19262 · SGD:S000002555PMID:12134146 Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu