P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL1532

This family has 14 members: 3 Arabidopsis thaliana, 1 Caenorhabditis elegans, 2 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/OrthoMCL1532
14 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_199717.2 · TAIR:locus:2155184 (K20J1.3 · K20J1_3 · AT5G49060)⌘
A. thalianaNCBI:NP_196194.1 · TAIR:locus:2166404 (MJJ3_16 · MJJ3.16 · AT5G05750)⌘
A. thalianaNCBI:NP_191293.1 · TAIR:locus:2082538 (F28O9.190 · AT3G57340)⌘
C. elegansWB:WBGene00001019 (B0035.14 · dnj-1) · UniProtKB:Q17438⌘
D. rerioENSEMBL:ENSDARP00000072882
D. rerioUniProtKB:Q7SXR2 · ZFIN:ZDB-GENE-030131-2725 (dnajb12)DnaJ (Hsp40) homolog, subfamily B, member 12⌘
D. discoideumUniProtKB:Q54TF9 · dictyBase:DDB_G0281775 (DDB_G0281775)DnaJ-like protein.⌘
D. melanogasterUniProtKB:Q9VFP0 · FB:FBgn0038195 (CG3061)dnaJ like2⌘
G. gallusUniProtKB:Q5F3M7 (RCJMB04_13a9 · IPI00600810 · Q5F3M7) · ENTREZ:423707⌘
H. sapiensENSEMBL:ENSG00000148719 · UniProtKB:Q9NXW2 (DNAJB12 · DJB12_HUMAN · IPI00014400 · Q9NXW2)DnaJ homolog subfamily B member 12⌘
M. musculusUniProtKB:Q9QYI4 · MGI:MGI:1931881 (mDj10 · Dnajb12)DnaJ (Hsp40) homolog, subfamily B, member 12⌘
R. norvegicusUniProtKB:Q5FVC4 · RGD:1359677 (Dnajb12)DnaJ (Hsp40) homolog, subfamily B, member 12⌘
S. cerevisiaeUniProtKB:P48353 · SGD:S000004771 (HLJ1 · YMR161W)Co-chaperone for Hsp40p, anchored in the ER membrane⌘
S. pombeUniProtKB:O13633 · GeneDB_Spombe:SPBC17A3.05c (SPBC17A3.05c)DNAJ/DUF1977 DNAJB12 homolog⌘
ProteinPublicationCurator Notes
UniProtKB:P48353 · SGD:S000004771PMID:14657499 Willingham S, et al. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science. 2003 Dec 5;302(5651):1769-72.The H. sapiens protein O60884 complements a homologous mutation in S. cerevisiae. The human ortholog DNAJA2 (O60884) was overexpressed in the yeast hlj1 null mutant.
UniProtKB:P48353 · SGD:S000004771PMID:14657499 Willingham S, et al. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science. 2003 Dec 5;302(5651):1769-72.The H. sapiens protein DNAJA2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P48353 · SGD:S000004771PMID:19748898 Vembar SS, et al. The mammalian Hsp40 ERdj3 requires its Hsp70 interaction and substrate-binding properties to complement various yeast Hsp40-dependent functions. J Biol Chem. 2009 Nov 20;284(47):32462-71.The H. sapiens protein DNAJB11 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu