P-POD: Princeton Protein Orthology Database: GO3/OrthoMCL12945

This family has 4 members: 3 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/OrthoMCL12945
4 members.
OrganismProtein (Synonyms)DescriptionAmiGO
S. cerevisiaeUniProtKB:P13587 · SGD:S000002447 (HOR6 · PMR2 · YDR040C · ENA1)P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance⌘
S. cerevisiaeUniProtKB:Q01896 · SGD:S000002446 (YDR039C · ENA2)P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance⌘
S. cerevisiaeUniProtKB:Q12691 · SGD:S000002445 (YDR038C · ENA5)Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family⌘
S. pombeUniProtKB:P22189 · GeneDB_Spombe:SPBC839.06 (SPBC839.06 · cta3)P-type ATPase, calcium transporting Cta3⌘
ProteinPublicationCurator Notes
UniProtKB:P13587 · SGD:S000002447PMID:9430707 Bañuelos MA, et al. P-type ATPases mediate sodium and potassium effluxes in Schwanniomyces occidentalis. J Biol Chem. 1998 Jan 16;273(3):1640-6.The S. occidentalis protein ENA1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P13587 · SGD:S000002447PMID:14991656 Nakayama H, et al. Yeast plasma membrane Ena1p ATPase alters alkali-cation homeostasis and confers increased salt tolerance in tobacco cultured cells. Biotechnol Bioeng. 2004 Mar 30;85(7):776-89.The S. cerevisiae protein ENA1 was expressed in N. tabacum, but complementation was not directly tested. This paper describes functional expression of yeast ENA1 in tobacco.
UniProtKB:Q01896 · SGD:S000002446PMID:15702539 Kinclová-Zimmermannová O, et al. Rice Na+/H+-antiporter Nhx1 partially complements the alkali-metal-cation sensitivity of yeast strains lacking three sodium transporters. Folia Microbiol (Praha). 2004;49(5):519-25.The O. sativa protein NHX1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows that rice NHX1 partially restores growth to a yeast ena1 ena2 nha1 nhx1 mutant grown in high salt.
UniProtKB:P13587 · SGD:S000002447PMID:15702539 Kinclová-Zimmermannová O, et al. Rice Na+/H+-antiporter Nhx1 partially complements the alkali-metal-cation sensitivity of yeast strains lacking three sodium transporters. Folia Microbiol (Praha). 2004;49(5):519-25.The O. sativa protein NHX1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows that rice NHX1 partially restores growth to a yeast ena1 ena2 nha1 nhx1 mutant grown in high salt.
UniProtKB:P13587 · SGD:S000002447PMID:15907686 Brini F, et al. Cloning and characterization of a wheat vacuolar cation/proton antiporter and pyrophosphatase proton pump. Plant Physiol Biochem. 2005 Apr;43(4):347-54.The T. aestivum protein TVP1 complements a homologous mutation in S. cerevisiae.
UniProtKB:Q01896 · SGD:S000002446PMID:16232587 Watanabe Y, et al. Characterization of the Na+-ATPase gene (ZENA1) from the salt-tolerant yeast Zygosaccharomyces rouxii. J Biosci Bioeng. 1999;88(2):136-42.The Z. rouxii protein ZENA1 complements a homologous mutation in S. cerevisiae. This paper shows that ZENA1 can restore growth to a yeast ena1 ena2 mutant grown in high salt.
UniProtKB:P13587 · SGD:S000002447PMID:16232587 Watanabe Y, et al. Characterization of the Na+-ATPase gene (ZENA1) from the salt-tolerant yeast Zygosaccharomyces rouxii. J Biosci Bioeng. 1999;88(2):136-42.The Z. rouxii protein ZENA1 complements a homologous mutation in S. cerevisiae. This paper shows that ZENA1 can restore growth to a yeast ena1 ena2 mutant grown in high salt.
UniProtKB:P13587 · SGD:S000002447PMID:16303259 Velkova K, et al. The Debaryomyces hansenii NHA1 gene encodes a plasma membrane alkali-metal-cation antiporter with broad substrate specificity. Gene. 2006 Mar 15;369:27-34.The D. hansenii protein DhNHA1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows functional expression of D. hansenii DhNHA1 in an S. cerevisiae ena1 nha1 double mutant.
UniProtKB:P13587 · SGD:S000002447PMID:17311588 Montiel V, et al. Intracellular Na and K distribution in Debaryomyces hansenii. Cloning and expression in Saccharomyces cerevisiae of DhNHX1. FEMS Yeast Res. 2007 Jan;7(1):102-9.The D. hansenii protein DhNHX1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows functional expression of DhNHX1 in a yeast ena1-4 nhx1 nha1 mutant.
UniProtKB:P13587 · SGD:S000002447PMID:9238019 Liang F, et al. ECA1 complements yeast mutants defective in Ca2+ pumps and encodes an endoplasmic reticulum-type Ca2+-ATPase in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8579-84.The A. thaliana protein AT1G07810.1 does not complement a homologous mutation in S. cerevisiae. This paper shows that A. thaliana AT1G07810.1 does not complement a yeast ena1 (alias pmr2) null mutant and does not function as a Na+ and Li+ efflux pump.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
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