P-POD: Princeton Protein Orthology Database: GO3/Nens975

This family has 22 members: 2 Arabidopsis thaliana, 2 Caenorhabditis elegans, 3 Danio rerio, 2 Dictyostelium discoideum, 2 Drosophila melanogaster, 1 Escherichia coli, 2 Gallus gallus, 2 Homo sapiens, 2 Mus musculus, 1 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens975
22 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_176826.1 · TAIR:locus:2028982 (AT1G66530 · F28G11.14 · F28G11_14)⌘
A. thalianaNCBI:NP_194360.1 · TAIR:locus:2136794 (T25K17.110 · T25K17_110 · emb1027 · AT4G26300)embryo defective 1027⌘
C. elegansWB:WBGene00004679 (F26F4.10 · rrt-1) · UniProtKB:Q19825⌘
C. elegansWB:WBGene00004680 (rrt-2 · C29H12.1) · UniProtKB:Q18316⌘
D. rerioENSEMBL:ENSDARP00000012870
D. rerioUniProtKB:Q6PGW8 · ZFIN:ZDB-GENE-040426-1244 (rars2)arginyl-tRNA synthetase 2, mitochondrial (putative)⌘
D. rerioUniProtKB:Q7ZVF4 · ZFIN:ZDB-GENE-030131-9014 (rars)arginyl-tRNA synthetase⌘
D. discoideumUniProtKB:Q558Z0 · dictyBase:DDB_G0272867 (ArgRS · argS · argS1)arginyl-tRNA synthetase, arginine-tRNA ligase⌘
D. discoideumUniProtKB:Q54JT6 · dictyBase:DDB_G0287803 (argS2 · ArgRS · argS)arginyl-tRNA synthetase, arginine-tRNA ligase⌘
D. melanogasterUniProtKB:Q9VXN4 · FB:FBgn0027093 (Aats-arg · RRS · ArgRS · CG9020)Arginyl-tRNA synthetase · Arginyl-tRNA Ligase⌘
D. melanogasterUniProtKB:Q8SXK2 · FB:FBgn0037526 (CG10092 · atl)arginyl tRNA ligase⌘
E. coliUniProtKB:P11875 · ECOLI:ARGS-MONOMER (ArgS · ECK1877 · lov-1 · lov · b1876 · argS)arginyl-tRNA synthetase⌘
G. gallusNCBI:XP_419847 · ENTREZ:421823
G. gallusENTREZ:416168 · UniProtKB:Q5ZM11 (IPI00586083 · RCJMB04_3h11 · SYRC_CHICK · Q5ZM11 · RARS)Arginyl-tRNA synthetase, cytoplasmic⌘
H. sapiensENSEMBL:ENSG00000113643 · UniProtKB:P54136 (P54136 · SYRC_HUMAN · IPI00004860 · IPI00759723 · RARS)Arginyl-tRNA synthetase, cytoplasmic⌘
H. sapiensENSEMBL:ENSG00000146282 · UniProtKB:Q5T160 (IPI00549566 · Q5T160 · RARSL · RARS2 · SYRM_HUMAN)Probable arginyl-tRNA synthetase, mitochondrial⌘
M. musculusUniProtKB:Q9D0I9 · MGI:MGI:1914297 (Rars)arginyl-tRNA synthetase⌘
M. musculusUniProtKB:Q3U186 · MGI:MGI:1923596 (PRO1992 · Rarsl · Rars2)arginyl-tRNA synthetase 2, mitochondrial⌘
R. norvegicusNCBI:XP_001065097 · RGD:1305419 (Rars2)arginyl-tRNA synthetase 2, mitochondrial⌘
S. cerevisiaeUniProtKB:Q05506 · SGD:S000002749 (RRS1 · YDR341C)Arginyl-tRNA synthetase, proposed to be cytoplasmic but the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies⌘
S. cerevisiaeUniProtKB:P38714 · SGD:S000001133 (YHR091C · MSR1)Mitochondrial arginyl-tRNA synthetase⌘
S. pombeUniProtKB:O74781 · GeneDB_Spombe:SPBC25B2.09c (mrs1 · SPBC25B2.09c · rrs1)mitochondrial and cytoplasmic arginine-tRNA ligase Rrs1/Mrs1⌘
ProteinPublicationCurator Notes
UniProtKB:P38714 · SGD:S000001133PMID:22569581 Cassandrini D, et al. Pontocerebellar hypoplasia type 6 caused by mutations in RARS2: definition of the clinical spectrum and molecular findings in five patients. J Inherit Metab Dis. 2013 Jan;36(1):43-53.The H. sapiens protein RARS2 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000146282 · UniProtKB:Q5T160#611523 PONTOCEREBELLAR HYPOPLASIA TYPE 6; PCH6;;ENCEPHALOPATHY, FATAL INFANTILE, WITH MITOCHONDRIAL RESPIRATORY CHAINDEFECTS
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