P-POD: Princeton Protein Orthology Database: GO3/Nens94

This family has 92 members: 14 Arabidopsis thaliana, 9 Caenorhabditis elegans, 6 Danio rerio, 13 Dictyostelium discoideum, 4 Drosophila melanogaster, 5 Escherichia coli, 7 Gallus gallus, 7 Homo sapiens, 6 Mus musculus, 5 Rattus norvegicus, 11 Saccharomyces cerevisiae, 5 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens94
92 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2151581 (K11J9.5 · K11J9_5 · AT5G61510) · NCBI:NP_200959.2⌘
A. thalianaNCBI:NP_188576.1 · TAIR:locus:2090704 (CAD-C · CAD4 · CAD · ATCAD4 · MLD14.30 · AT3G19450)CINNAMYL ALCOHOL DEHYDROGENASE 4⌘
A. thalianaNCBI:NP_195511.1 · TAIR:locus:2005527 (ELI3 · F20D10_100 · AT4G37980 · F20D10.100 · ELI3-1)ELICITOR-ACTIVATED GENE 3 · ELICITOR-ACTIVATED GENE 3-1⌘
A. thalianaNCBI:NP_179780.1 · TAIR:locus:2052494
A. thalianaNCBI:NP_179765.1 · TAIR:locus:2052516
A. thalianaNCBI:NP_195512.1 · TAIR:locus:2005528 (CI0009 · AT4G37990 · ELI3-2 · F20D10.110 · F20D10_110 · ELI3 · ATCAD8 · CAD-B2)CINNAMYL-ALCOHOL DEHYDROGENASE B2 · CINNAMYL-ALCOHOL DEHYDROGENASE · ARABIDOPSIS THALIANA CINNAMYL-ALCOHOL DEHYDROGENASE 8 · ELICITOR-ACTIVATED GENE 3 · ELICITOR-ACTIVATED GENE 3-2⌘
A. thalianaNCBI:NP_177412.1 · TAIR:locus:2030210 (F28P22.13 · AT1G72680 · F28P22_13 · ATCAD1)CINNAMYL ALCOHOL DEHYDROGENASE 1⌘
A. thalianaNCBI:NP_195510.1 · TAIR:locus:2120968 (CAD6 · AT4G37970 · F20D10.90 · F20D10_90 · ATCAD6)CINNAMYL ALCOHOL DEHYDROGENASE 6⌘
A. thalianaNCBI:NP_193889.1 · TAIR:locus:2119682 (F17L22.40 · AT4G21580)⌘
A. thalianaNCBI:NP_566881.1 · TAIR:locus:2102664 (AT3G45770 · F16L2.2)⌘
A. thalianaNCBI:NP_175390.2 · TAIR:locus:2012166 (F14J22_10 · NQR · F14J22.10 · AT1G49670)⌘
A. thalianaNCBI:NP_195643.1 · TAIR:locus:2136278
A. thalianaNCBI:NP_200010.1 · TAIR:locus:2173093
A. thalianaNCBI:NP_195149.1 · TAIR:locus:2124311 (CAD-5 · AT4G34230 · CAD5 · ATCAD5 · F10M10.11)cinnamyl alcohol dehydrogenase 5⌘
C. elegansWB:WBGene00010790 (sodh-1 · K12G11.3) · UniProtKB:Q17334 (sodh-1 · K12G11.3 · ADH1_CAEEL)Alcohol dehydrogenase 1⌘⌘
C. elegansWB:WBGene00010791 (K12G11.4 · sodh-2) · UniProtKB:O45687⌘
C. elegansWB:WBGene00012375 (W09H1.5) · UniProtKB:O45903⌘
C. elegansWB:WBGene00012970 (Y48A6B.9) · UniProtKB:Q9XXC8 (MECR2_CAEEL · Y48A6B.9)Probable trans-2-enoyl-CoA reductase 2, mitochondrial⌘⌘
C. elegansWB:WBGene00009554 (F39B2.3) · UniProtKB:O45496⌘
C. elegansWB:WBGene00011003 (R04B5.5) · UniProtKB:Q21702⌘
C. elegansWB:WBGene00011004 (R04B5.6) · UniProtKB:Q21703⌘
C. elegansWB:WBGene00014096 (ZK829.7) · UniProtKB:Q23624 (ZK829.7)Protein ZK829.7, confirmed by transcript evidence⌘⌘
C. elegansWB:WBGene00017060 (D2063.1) · UniProtKB:Q9UAT1 (D2063.1)Putative uncharacterized protein⌘⌘
D. rerioENSEMBL:ENSDARP00000021398
D. rerioENSEMBL:ENSDARP00000043156
D. rerioENSEMBL:ENSDARP00000069904
D. rerioUniProtKB:Q6GQN8 · ZFIN:ZDB-GENE-050417-399 (mecr)mitochondrial trans-2-enoyl-CoA reductase⌘
D. rerioUniProtKB:Q8JFV8 · ZFIN:ZDB-GENE-030616-178 (vat1)vesicle amine transport protein 1 homolog (T californica)⌘
D. rerioUniProtKB:Q5CZU9 · ZFIN:ZDB-GENE-050306-24 (cryz)crystallin, zeta (quinone reductase)⌘
D. discoideumNCBI:EAL71580.1 · dictyBase:DDB_G0271780 (DDB_G0271780)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL73614.2 · dictyBase:DDB_G0268322 (DDB_G0268322)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL70951.1 · dictyBase:DDB_G0272628 (DDB_G0272628)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL70651.1 · dictyBase:DDB_G0273921 (DDB_G0273921)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL70476.1 · dictyBase:DDB_G0274085 (DDB_G0274085)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL71372.1 · dictyBase:DDB_G0272440 (DDB_G0272440)putative quinone oxidoreductase, alcohol dehydrogenase⌘
D. discoideumNCBI:EAL71521.2 · dictyBase:DDB_G0271884 (DDB_G0271884)putative quinone oxidoreductase, alcohol dehydrogenase⌘
D. discoideumNCBI:EAL69318.1 · dictyBase:DDB_G0276037 (DDB_G0276037)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL70795.1 · dictyBase:DDB_G0273155 (DDB_G0273155)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL71530.1 · dictyBase:DDB_G0271680 (DDB_G0271680)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL71560.1 · dictyBase:DDB_G0271740 (DDB_G0271740)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumNCBI:EAL66795.1 · dictyBase:DDB_G0280997 (DDB_G0280997)zinc-containing alcohol dehydrogenase (ADH)⌘
D. discoideumUniProtKB:Q54YT4 · dictyBase:DDB_G0278095 (mecr)trans-2-enoyl-CoA reductase, 2-enoyl thioester reductase⌘
D. melanogasterFB:FBgn0033883 (DM_7303260 · CG16935) · UniProtKB:Q9V6U9⌘
D. melanogasterUniProtKB:O96299 · FB:FBgn0022359 (Sdh-2 · CG4649 · Sodh-2 · SODH-2 · DM_7299382 · Sdh)Sorbitol dehydrogenase-2⌘
D. melanogasterUniProtKB:O97479 · FB:FBgn0024289 (DM_7298873 · Sodh-1 · CG1982 · Sodh · BG:DS00464.2 · Sdh-1)Sorbitol dehydrogenase 1 · Sorbitol dehydrogenase like⌘
D. melanogasterFB:FBgn0033188 (CG1600) · UniProtKB:Q961L4⌘
E. coliUniProtKB:P39451 · ECOLI:ADHP-MONOMER (yddN · adhP · ECK1472 · b1478 · AdhP)ethanol dehydrogenase⌘
E. coliUniProtKB:P28304 · ECOLI:QOR-MONOMER (qor · Qor · NADPH-dependent · hcz · ECK4043 · Hcz · b4051 · Hzc · hzc · B4051)quinone oxidoreductase⌘
E. coliUniProtKB:P75691 · ECOLI:G6190-MONOMER (b0325 · YahK · ECK0323 · yahK)predicted oxidoreductase, Zn-dependent and NAD(P)-binding⌘
E. coliUniProtKB:P77280 · ECOLI:G6961-MONOMER (ydjJ · YdjJ · ECK1772 · b1774)predicted oxidoreductase, Zn-dependent and NAD(P)-binding⌘
E. coliUniProtKB:P27250 · ECOLI:EG11436-MONOMER (b4269 · yjgB · YjgB · ECK4262)predicted alcohol dehydrogenase, Zn-dependent and NAD(P)-binding⌘
G. gallusNCBI:XP_419096 · ENTREZ:421010
G. gallusNCBI:XP_417748 · ENTREZ:419601
G. gallusNCBI:XP_413719 · ENTREZ:415332
G. gallusNCBI:XP_419987 · ENTREZ:421977
G. gallusNCBI:XP_427969 · ENTREZ:430410
G. gallusNCBI:XP_418130 · ENTREZ:420009
G. gallusENTREZ:772289 · UniProtKB:Q5ZHT3 (Q5ZHT3 · IPI00578826 · RCJMB04_33h20)⌘
H. sapiensENSEMBL:ENSG00000140263 · UniProtKB:Q00796 (SORD · DHSO_HUMAN · IPI00216057 · Q00796)Sorbitol dehydrogenase⌘
H. sapiensENSEMBL:ENSG00000116353 · UniProtKB:Q9BV79 (CGI-63 · MECR_HUMAN · Q9BV79 · IPI00306159 · NBRF1 · MECR)Trans-2-enoyl-CoA reductase, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000115129 · UniProtKB:Q53FA7 (IPI00384643 · IPI00418440 · PIG3 · TP53I3 · Q53FA7 · QORX_HUMAN)Putative quinone oxidoreductase⌘
H. sapiensENSEMBL:ENSG00000116791 · UniProtKB:Q08257 (QOR_HUMAN · CRYZ · Q08257 · IPI00000792)Quinone oxidoreductase⌘
H. sapiensENSEMBL:ENSG00000171724 · UniProtKB:Q9HCJ6 (IPI00030578 · KIAA1576 · VAT1L · VAT1L_HUMAN · Q9HCJ6)Synaptic vesicle membrane protein VAT-1 homolog-like⌘
H. sapiensENSEMBL:ENSG00000108828 · UniProtKB:Q99536 (VAT1 · VAT1_HUMAN · IPI00156689 · Q99536)Synaptic vesicle membrane protein VAT-1 homolog⌘
H. sapiensENSEMBL:ENSG00000180011 · UniProtKB:Q8N4Q0 (Q8N4Q0 · IPI00166738 · ZADH2 · ZADH2_HUMAN)Zinc-binding alcohol dehydrogenase domain-containing protein 2⌘
M. musculusUniProtKB:Q64442 · MGI:MGI:98266 (Sord · Sodh-1 · Sdh1 · Sdh-1)sorbitol dehydrogenase⌘
M. musculusUniProtKB:Q9DCS3 · MGI:MGI:1349441 (Nrbf1 · Mecr)mitochondrial trans-2-enoyl-CoA reductase⌘
M. musculusUniProtKB:P47199 · MGI:MGI:88527 (SEZ9 · Cryz)quinone reductase · crystallin, zeta⌘
M. musculusUniProtKB:Q80TB8 · MGI:MGI:2142534 (Vat1l)vesicle amine transport protein 1 homolog-like (T. californica)⌘
M. musculusUniProtKB:Q62465 · MGI:MGI:1349450 (Vat1 · VAT-1)vesicle amine transport protein 1 homolog (T californica)⌘
M. musculusUniProtKB:Q8BGC4 · MGI:MGI:2444835 (Zadh2)zinc binding alcohol dehydrogenase, domain containing 2⌘
R. norvegicusNCBI:XP_214526 · RGD:1309999
R. norvegicusUniProtKB:P27867 · RGD:3734 (Sord)sorbitol dehydrogenase⌘
R. norvegicusUniProtKB:Q9Z311 · RGD:3208 (Mecr)mitochondrial trans-2-enoyl-CoA reductase⌘
R. norvegicusUniProtKB:Q6AYT0 · RGD:1311639 (Cryz)crystallin, zeta⌘
R. norvegicusUniProtKB:Q3MIE4 · RGD:1308943 (Vat1)vesicle amine transport protein 1 homolog (T californica)⌘
S. cerevisiaeUniProtKB:P00330 · SGD:S000005446 (ADC1 · YOL086C · ADH1)Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers⌘
S. cerevisiaeUniProtKB:P00331 · SGD:S000004918 (YMR303C · ADR2 · ADH2)Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde⌘
S. cerevisiaeUniProtKB:P07246 · SGD:S000004688 (ADH3 · YMR083W)Mitochondrial alcohol dehydrogenase isozyme III⌘
S. cerevisiaeUniProtKB:P38113 · SGD:S000000349 (YBR145W · ADH5)Alcohol dehydrogenase isoenzyme V⌘
S. cerevisiaeUniProtKB:Q04894 · SGD:S000004937 (YMR318C · ADH6 · ADHVI)NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity⌘
S. cerevisiaeUniProtKB:P25377 · SGD:S000000702 (ADHVII · YCR105W · ADH7)NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity⌘
S. cerevisiaeUniProtKB:P35497 · SGD:S000003920 (SDH1 · SOR1 · YJR159W)Sorbitol dehydrogenase⌘
S. cerevisiaeUniProtKB:Q07786 · SGD:S000002405 (SOR2 · YDL246C)Protein of unknown function⌘
S. cerevisiaeUniProtKB:P38071 · SGD:S000000230 (YBR026C · MRF1' · MRF1 · ETR1)2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family⌘
S. cerevisiaeUniProtKB:P38230 · SGD:S000000250 (ZTA1 · YBR046C)NADPH-dependent quinone reductase, GFP-tagged protein localizes to the cytoplasm and nucleus⌘
S. cerevisiaeUniProtKB:Q07993 · SGD:S000004060 (XYL2 · YLR070C)Xylitol dehydrogenase, converts xylitol to D-xylulose⌘
S. pombeUniProtKB:P00332 · GeneDB_Spombe:SPCC13B11.01 (adh · SPCC13B11.01 · adh1)alcohol dehydrogenase Adh1⌘
S. pombeUniProtKB:P36624 · GeneDB_Spombe:SPBC1773.05c (SPBC1773.05c · tms1)hexitol dehydrogenase⌘
S. pombeUniProtKB:Q10488 · GeneDB_Spombe:SPAC26F1.04c (SPAC26F1.04c · etr1)enoyl-[acyl-carrier protein] reductase⌘
S. pombeUniProtKB:O74489 · GeneDB_Spombe:SPCC1442.16c (zta1 · SPCC1442.16c · SPCC285.01c)NADPH quinone oxidoreductase/ARE-binding protein⌘
S. pombeUniProtKB:O94564 · GeneDB_Spombe:SPBC1773.06c (SPBC1773.06c)alcohol dehydrogenase⌘
ProteinPublicationCurator Notes
UniProtKB:P00330 · SGD:S000005446PMID:6294096 Russell PR, et al. The primary structure of the alcohol dehydrogenase gene from the fission yeast Schizosaccharomyces pombe. J Biol Chem. 1983 Jan 10;258(1):143-9.The S. pombe protein Alcohol dehydrogenase complements a homologous mutation in S. cerevisiae.
UniProtKB:P00330 · SGD:S000005446PMID:10732677 Benos P, et al. Acquisition of a potential marker for insect transformation: isolation of a novel alcohol dehydrogenase gene from Bactrocera oleae by functional complementation in yeast. Mol Gen Genet. 2000 Feb;263(1):90-5.The C. capitata protein alcohol dehydrogenase complements a homologous mutation in S. cerevisiae. This paper describes the cloning of a C. capitata alcohol dehydrogenase gene by functional complementation of a yeast adh1 null mutant, however the cloned gene is unrelated in sequence to yeast ADH1.
UniProtKB:P00330 · SGD:S000005446PMID:10732677 Benos P, et al. Acquisition of a potential marker for insect transformation: isolation of a novel alcohol dehydrogenase gene from Bactrocera oleae by functional complementation in yeast. Mol Gen Genet. 2000 Feb;263(1):90-5.The B. oleae protein alcohol dehydrogenase complements a homologous mutation in S. cerevisiae.
UniProtKB:Q07993 · SGD:S000004060PMID:15184173 Toivari MH, et al. Endogenous xylose pathway in Saccharomyces cerevisiae. Appl Environ Microbiol. 2004 Jun;70(6):3681-6.The P. stipitis protein XDH was expressed in S. cerevisiae, but complementation was not directly tested. The authors expressed genes from P. stipitis in wild type S. cerevisiae and were not testing for complementation.
UniProtKB:Q07993 · SGD:S000004060PMID:15184173 Toivari MH, et al. Endogenous xylose pathway in Saccharomyces cerevisiae. Appl Environ Microbiol. 2004 Jun;70(6):3681-6.The P. stipitis protein XR was expressed in S. cerevisiae, but complementation was not directly tested. The authors expressed genes from P. stipitis in wild type S. cerevisiae and were not testing for complementation.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu