P-POD: Princeton Protein Orthology Database: GO3/Nens519

This family has 32 members: 3 Arabidopsis thaliana, 2 Caenorhabditis elegans, 3 Danio rerio, 3 Dictyostelium discoideum, 2 Drosophila melanogaster, 1 Escherichia coli, 3 Gallus gallus, 3 Homo sapiens, 3 Mus musculus, 3 Rattus norvegicus, 3 Saccharomyces cerevisiae, 3 Schizosaccharomyces pombe.

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GO3/Nens519
32 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2015233 (F16M19.6 · AT1G63160 · F16M19_6) · NCBI:NP_176504.1⌘
A. thalianaNCBI:NP_198126.1 · TAIR:locus:2180315
A. thalianaNCBI:NP_173839.1 · TAIR:locus:2032432 (F3I6.23 · AT1G24290 · F3I6_23)⌘
C. elegansWB:WBGene00004338 (F58F6.4 · rfc-2) · UniProtKB:O44175 (F58F6.4 · rfc-2)Rfc (Dna replication factor) family protein 2⌘⌘
C. elegansWB:WBGene00004339 (rfc-3 · C39E9.13) · UniProtKB:Q18547 (rfc-3 · C39E9.13)Protein C39E9.13, confirmed by transcript evidence⌘⌘
D. rerioZFIN:ZDB-GENE-050306-29 (zgc:110810) · UniProtKB:Q5CZN5⌘
D. rerioZFIN:ZDB-GENE-040426-2415 (zgc:85976) · UniProtKB:Q6NW46⌘
D. rerioUniProtKB:Q8AW06 · ZFIN:ZDB-GENE-020809-3 (rfc3)replication factor C (activator 1) 3⌘
D. discoideumUniProtKB:Q54E21 · dictyBase:DDB_G0291868 (rfc2)replication factor C subunit⌘
D. discoideumUniProtKB:Q54BN3 · dictyBase:DDB_G0293702 (rfc3)replication factor C subunit⌘
D. discoideumUniProtKB:Q75JU2 · dictyBase:DDB_G0272158 (DDB_G0272158)PUTATIVE HELICASE RUVBL⌘
D. melanogasterUniProtKB:P53034 · FB:FBgn0015287 (l(3)64Ai · rfc4 · RfC40 · rfc · l(3)rfc40 · rfc[40] · 154910_at · BEST:GH24992 · CG14999 · l(3)SH17 · rfc40 · Rfc40)Replication-factor-C 40kD subunit⌘
D. melanogasterUniProtKB:Q7KLW6 · FB:FBgn0028700 (n(2)k13807 · CG6258 · l(2)rfc38 · l(2)k13807 · BcDNA:LD06837 · Rfc38 · RfC38)DNA replication factor, 38k subunit · Replication factor C 38kD subunit⌘
E. coliUniProtKB:P0AAZ4 · ECOLI:EG12690-MONOMER (ECK0883 · b0892 · rarA · mgsA · ycaJ · RarA)recombination factor⌘
G. gallusNCBI:XP_418979 · ENTREZ:395089
G. gallusENTREZ:396542 · UniProtKB:P53033 (RFC2_CHICK · IPI00586061 · RFC2 · P53033)Replication factor C subunit 2⌘
G. gallusUniProtKB:Q5ZJP0 (RCJMB04_16m20 · Q5ZJP0 · IPI00593478) · ENTREZ:418907⌘
H. sapiensENSEMBL:ENSG00000049541 · UniProtKB:P35250 (IPI00218280 · IPI00017412 · RFC2 · RFC2_HUMAN · P35250)Replication factor C subunit 2⌘
H. sapiensENSEMBL:ENSG00000133119 · UniProtKB:P40938 (RFC3 · P40938 · RFC3_HUMAN · IPI00031521)Replication factor C subunit 3⌘
H. sapiensENSEMBL:ENSG00000124535 · UniProtKB:Q96S55 (WRNIP1 · IPI00102997 · Q96S55 · IPI00290314 · WRIP1_HUMAN · WHIP · IPI00645459 · IPI00642533)ATPase WRNIP1⌘
M. musculusUniProtKB:Q9WUK4 · MGI:MGI:1341868 (Recc2 · 40kDa · Rfc2)replication factor C (activator 1) 2⌘
M. musculusUniProtKB:Q8R323 · MGI:MGI:1916513 (38kDa · Rfc3 · Recc3)replication factor C (activator 1) 3⌘
M. musculusUniProtKB:Q91XU0 · MGI:MGI:1926153 (WHIP · Wrnip1)Werner helicase interacting protein 1⌘
R. norvegicusUniProtKB:Q641W4 · RGD:621198 (Rfc2)replication factor C (activator 1) 2⌘
R. norvegicusUniProtKB:Q8CG07 · RGD:628836 (Wrnip1)Werner helicase interacting protein 1⌘
R. norvegicusUniProtKB:Q5M830 · RGD:1306832 (Rfc3)replication factor C (activator 1) 3⌘
S. cerevisiaeUniProtKB:P40151 · SGD:S000005162 (YNL218W · MGS1)Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome⌘
S. cerevisiaeUniProtKB:P40339 · SGD:S000005454 (YOL094C · RFC4)Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon⌘
S. cerevisiaeUniProtKB:P38251 · SGD:S000000291 (YBR087W · RFC5)Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon⌘
S. pombeUniProtKB:O94449 · GeneDB_Spombe:SPAC1687.03c (SPAC1687.03c · rfc4)DNA replication factor C complex subunit Rfc4⌘
S. pombeUniProtKB:O94697 · GeneDB_Spombe:SPBC83.14c (SPBC83.14c · rfc5)DNA replication factor C complex subunit Rfc5⌘
S. pombeUniProtKB:O13984 · GeneDB_Spombe:SPAC26H5.02c (SPAC26H5.02c)DNA replication ATPase⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
UniProtKB:P40151 · SGD:S000005162#194050 WILLIAMS-BEUREN SYNDROME; WBS;;CHROMOSOME 7q11.23 DELETION SYNDROME;;WILLIAMS SYNDROME; WMS; WSHYPERCALCEMIA, INFANTILE, INCLUDED;;SUPRAVALVAR AORTIC STENOSIS, INCLUDED;;ELFIN FACIES WITH HYPERCALCEMIA
SGD Disease Papers (2)
UniProtKB:P40151 · SGD:S000005162PMID:18842586 Crosetto N, et al. (2008) Human Wrnip1 Is Localized in Replication Factories in a Ubiquitin-binding Zinc Finger-dependent Manner. J Biol Chem 283(50):35173-35185
PMID:12509289 Branzei D, et al. (2002) Characterization of the slow-growth phenotype of S. cerevisiae Whip/Mgs1 Sgs1 double deletion mutants. DNA Repair (Amst) 1(8):671-82
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