This family has 36 members: 3 Arabidopsis thaliana, 3 Caenorhabditis elegans, 5 Danio rerio, 2 Dictyostelium discoideum, 4 Drosophila melanogaster, 1 Escherichia coli, 3 Gallus gallus, 4 Homo sapiens, 4 Mus musculus, 4 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | TAIR:locus:2176202 (MWD22_24 · MWD22.24 · AT5G51290) · NCBI:NP_568756.2 |  | |
| A. thaliana | NCBI:NP_566064.1 · TAIR:locus:2063004 (T3F17.26 · AT2G46090) | | |
| A. thaliana | NCBI:NP_193885.2 · TAIR:locus:2119642 (F18E5_160 · SPHK1 · F18E5.160 · AT4G21540) | SPHINGOSINE KINASE 1 | |
| C. elegans | WB:WBGene00018674 · UniProtKB:Q10123 | ||
| C. elegans | WB:WBGene00007918 (C34C6.5 · sphk-1) · UniProtKB:Q18425 | | |
| C. elegans | WB:WBGene00020398 · UniProtKB:Q9TZI1 | ||
| D. rerio | ENSEMBL:ENSDARP00000078472 | ||
| D. rerio | ENSEMBL:ENSDARP00000078469 | ||
| D. rerio | UniProtKB:Q7ZW00 · ZFIN:ZDB-GENE-030131-6202 (agk) | acylglycerol kinase | |
| D. rerio | ZFIN:ZDB-GENE-070112-2262 (zgc:158263) · UniProtKB:A1L1R3 | | |
| D. rerio | UniProtKB:A5WVZ0 · ZFIN:ZDB-GENE-041210-210 (cerk) | ceramide kinase | |
| D. discoideum | UniProtKB:Q86KF9 · dictyBase:DDB_G0272522 (sgkA · SPHK · SK) | sphingosine kinase | |
| D. discoideum | UniProtKB:Q6B516 · dictyBase:DDB_G0284545 (SPHK · SK · sgkB) | sphingosine kinase | |
| D. melanogaster | FB:FBgn0032206 · UniProtKB:Q9VL10 | ||
| D. melanogaster | FB:FBgn0037315 (CG16708 · DCERK) · UniProtKB:Q9VNA6 | | |
| D. melanogaster | UniProtKB:Q9VYY8 · FB:FBgn0030300 (CG1747 · Sphk1 · Sk1 · SK1) | Sphingosine kinase 1 · Sphingosine kinase I | |
| D. melanogaster | UniProtKB:Q9VZW0 · FB:FBgn0052484 (Sk2 · Sphk2 · SK2 · CG32484 · CG2159) | sphingosine kinase 2 · Sphingosine kinase II · sphingosine kinase · Sphingosine kinase 2 | |
| E. coli | UniProtKB:P76407 · ECOLI:G7123-MONOMER (yegS · b2086 · ECK2082 · YegS) | lipid kinase | |
| G. gallus | NCBI:XP_416354 · ENTREZ:418121 | ||
| G. gallus | NCBI:XP_425374 · ENTREZ:427803 | ||
| G. gallus | UniProtKB:Q5F3H3 (RCJMB04_16p10 · Q5F3H3 · IPI00577721) · ENTREZ:425523 | | |
| H. sapiens | ENSEMBL:ENSG00000006530 · UniProtKB:Q53H12 (MULK · Q53H12 · IPI00019353 · AGK_HUMAN · AGK · IPI00553233) | Acylglycerol kinase, mitochondrial | |
| H. sapiens | ENSEMBL:ENSG00000100422 · UniProtKB:Q8TCT0 (KIAA1646 · Q8TCT0 · IPI00152433 · CERK1_HUMAN · CERK) | Ceramide kinase | |
| H. sapiens | ENSEMBL:ENSG00000176170 · UniProtKB:Q9NYA1 (SPK · Q9NYA1 · SPHK1 · SPHK1_HUMAN · IPI00790290 · SPHK · IPI00182048) | Sphingosine kinase 1 | |
| H. sapiens | ENSEMBL:ENSG00000063176 · UniProtKB:Q9NRA0 (SPHK2_HUMAN · IPI00215796 · IPI00024496 · Q9NRA0 · IPI00215795 · SPHK2) | Sphingosine kinase 2 | |
| M. musculus | UniProtKB:Q9ESW4 · MGI:MGI:1917173 (MuLK · Agk) | acylglycerol kinase | |
| M. musculus | UniProtKB:Q8K4Q7 · MGI:MGI:2386052 (Cerk) | ceramide kinase | |
| M. musculus | UniProtKB:Q8CI15 · MGI:MGI:1316649 (Sphk1 · SK1) | sphingosine kinase 1 | |
| M. musculus | UniProtKB:Q9JIA7 · MGI:MGI:1861380 (SPHK2_MOUSE · IPI00310333 · Sphk2) | sphingosine kinase 2 | |
| R. norvegicus | NCBI:XP_217019 · RGD:1305019 (Cerk) | ceramide kinase | |
| R. norvegicus | NCBI:XP_578248 · RGD:1562046 (Agk) | acylglycerol kinase | |
| R. norvegicus | UniProtKB:Q91V26 · RGD:620048 (Sphk1) | sphingosine kinase 1 | |
| R. norvegicus | UniProtKB:Q6AYB2 · RGD:1307757 (Sphk2) | sphingosine kinase 2 | |
| S. cerevisiae | UniProtKB:Q12246 · SGD:S000005697 (YOR171C · LCB4) | Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes | |
| S. cerevisiae | UniProtKB:Q06147 · SGD:S000004250 (LCB5 · YLR260W) | Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules | |
| S. pombe | UniProtKB:O14159 · GeneDB_Spombe:SPAC4A8.07c (SPAC4A8.07c) | sphingoid long chain base kinase | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |