P-POD: Princeton Protein Orthology Database: GO3/Nens4048

This family has 10 members: 1 Caenorhabditis elegans, 2 Danio rerio, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens4048
10 members.
OrganismProtein (Synonyms)DescriptionAmiGO
C. elegansUniProtKB:O45870 · WB:WBGene00012105
D. rerioENSEMBL:ENSDARP00000069090
D. rerioUniProtKB:Q4LEU0 · ZFIN:ZDB-GENE-051014-1 (smpd2)sphingomyelin phosphodiesterase 2, neutral⌘
D. melanogasterUniProtKB:Q9VZS6 · FB:FBgn0035421 (nSMase · CG12034)⌘
G. gallusNCBI:XP_001232516 · ENTREZ:770663
H. sapiensENSEMBL:ENSG00000135587 · UniProtKB:O60906 (O60906 · SMPD2 · NSMA_HUMAN · IPI00017670)Sphingomyelin phosphodiesterase 2⌘
M. musculusUniProtKB:O70572 · MGI:MGI:1278330 (nSMase · Smpd2)sphingomyelin phosphodiesterase 2, neutral⌘
R. norvegicusUniProtKB:Q9ET64 · RGD:619753 (Smpd2)sphingomyelin phosphodiesterase 2, neutral⌘
S. cerevisiaeUniProtKB:P40015 · SGD:S000000821 (YER019W · ISC1)Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide⌘
S. pombeUniProtKB:O74369 · GeneDB_Spombe:SPBC32F12.01c (SPBC685.10c · SPBC32F12.01c)inositol phosphosphingolipid phospholipase C⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
SGD Disease Papers (1)
UniProtKB:P40015 · SGD:S000000821PMID:16981685 Clarke CJ, et al. (2006) The extended family of neutral sphingomyelinases. Biochemistry 45(38):11247-56
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu