P-POD: Princeton Protein Orthology Database: GO3/Nens369

This family has 39 members: 15 Arabidopsis thaliana, 5 Caenorhabditis elegans, 1 Danio rerio, 3 Dictyostelium discoideum, 3 Drosophila melanogaster, 3 Homo sapiens, 3 Mus musculus, 3 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/Nens369
39 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_172566.2 · TAIR:locus:2197459 (AT1G10970 · ZIP4 · T19D16_11 · ATZIP4 · T19D16.11)ZINC TRANSPORTER 4 PRECURSOR⌘
A. thalianaNCBI:NP_172022.1 · TAIR:locus:2207140 (YUP8H12_8 · YUP8H12.8 · ZIP5 · AT1G05300)⌘
A. thalianaNCBI:NP_001031670.1 · TAIR:locus:2133950 (AT4G19680 · T16H5.40 · T16H5_40 · IRT2)⌘
A. thalianaNCBI:NP_564766.1 · TAIR:locus:2206011 (IRT3 · T7P1.10 · T7P1_10 · AT1G60960)⌘
A. thalianaNCBI:NP_180569.1 · TAIR:locus:2045634 (ZIP6 · ATZIP6 · T27E13_18 · T27E13.18 · AT2G30080)⌘
A. thalianaNCBI:NP_195028.1 · TAIR:locus:2123787 (ZIP9 · AT4G33020 · ATZIP9 · F4I10.1)⌘
A. thalianaNCBI:NP_680394.1 · TAIR:locus:504954991 (AT5G45105 · ZIP8)ZINC TRANSPORTER 8 PRECURSOR⌘
A. thalianaNCBI:NP_174411.2 · TAIR:locus:2197520 (ZIP10 · T19E23_6 · AT1G31260 · T19E23.6)ZINC TRANSPORTER 10 PRECURSOR⌘
A. thalianaNCBI:NP_187881.1 · TAIR:locus:2087705 (MBK21.8 · ZIP1 · AT3G12750)ZINC TRANSPORTER 1 PRECURSOR⌘
A. thalianaNCBI:NP_180786.1 · TAIR:locus:2062576 (T32F6.21 · AT2G32270 · T32F6_21 · ZIP3)⌘
A. thalianaNCBI:NP_200760.1 · TAIR:locus:2148398 (ZIP2 · F2O15_25 · F2O15.25 · AT5G59520)⌘
A. thalianaNCBI:NP_178488.1 · TAIR:locus:2827434 (ZIP7 · F3L12.21 · AT2G04032)ZINC TRANSPORTER 7 PRECURSOR⌘
A. thalianaNCBI:NP_564703.1 · TAIR:locus:2012020 (F14J16.16 · ZIP11 · AT1G55910)ZINC TRANSPORTER 11 PRECURSOR⌘
A. thalianaNCBI:NP_567590.3 · TAIR:locus:2133965 (T16H5.50 · IRT1 · AT4G19690 · T16H5_50)iron-regulated transporter 1⌘
A. thalianaNCBI:NP_201022.1 · TAIR:locus:2174098 (AT5G62160 · MTG10_20 · MTG10.20 · AtZIP12)ZINC TRANSPORTER 12 PRECURSOR⌘
C. elegansWB:WBGene00009286 (F31C3.4) · UniProtKB:O62192⌘
C. elegansWB:WBGene00018897 (F55F8.9) · UniProtKB:P91348⌘
C. elegansWB:WBGene00017936 (F30B5.7) · UniProtKB:Q19913⌘
C. elegansWB:WBGene00014669 (C06G8.3) · UniProtKB:Q6BEU0⌘
C. elegansWB:WBGene00013207 (Y54G9A.4) · UniProtKB:Q9XWH3⌘
D. rerioUniProtKB:P59889 · ZFIN:ZDB-GENE-030131-9917 (slc39a1)solute carrier family 39 (zinc transporter), member 1⌘
D. discoideumNCBI:EAL70763.1 · dictyBase:DDB_G0273091 (DDB_G0273091)ZIP family zinc transporter, zinc/iron permease⌘
D. discoideumUniProtKB:Q54T89 · dictyBase:DDB_G0281921 (DDB_G0281921)ZIP zinc transporter protein, zinc/iron permease⌘
D. discoideumUniProtKB:Q75JD1 · dictyBase:DDB_G0271672 (DDB_G0271672)ZIP zinc transporter protein, zinc/iron permease⌘
D. melanogasterFB:FBgn0033097 (CG9430) · UniProtKB:A1Z6P0⌘
D. melanogasterUniProtKB:Q7JZR2 · FB:FBgn0033096 (dZIP1 · CG9428 · ZIP1)Zinc/iron regulated transporter-related protein 1⌘
D. melanogasterUniProtKB:Q9VEX1 · FB:FBgn0038412 (CG6898 · Zip3 · ZIP3)Zinc/iron regulated transporter-related protein 3⌘
H. sapiensENSEMBL:ENSG00000143570 · UniProtKB:Q9NY26 (ZIRTL · CGI-08 · CGI-71 · SLC39A1 · Q9NY26 · IRT1 · ZIP1 · IPI00100585 · S39A1_HUMAN)Zinc transporter ZIP1⌘
H. sapiensENSEMBL:ENSG00000165794 · UniProtKB:Q9NP94 (S39A2_HUMAN · ZIP2 · SLC39A2 · IPI00005148 · Q9NP94)Zinc transporter ZIP2⌘
H. sapiensENSEMBL:ENSG00000141873 · UniProtKB:Q9BRY0 (S39A3_HUMAN · IPI00382918 · SLC39A3 · IPI00029337 · Q9BRY0 · ZIP3)Zinc transporter ZIP3⌘
M. musculusNCBI:NP_001034765 · MGI:MGI:2684326 (Slc39a2 · zip2)solute carrier family 39 (zinc transporter), member 2⌘
M. musculusNCBI:NP_038929 · MGI:MGI:1353474 (Zirtl · Slc39a1 · zip1)solute carrier family 39 (zinc transporter), member 1⌘
M. musculusUniProtKB:Q99K24 · MGI:MGI:2147269 (zip3 · Slc39a3)solute carrier family 39 (zinc transporter), member 3⌘
R. norvegicusNCBI:XP_001075087 · RGD:1305241 (Slc39a1)solute carrier family 39 (zinc transporter), member 1⌘
R. norvegicusNCBI:XP_001064953 · RGD:1306291 (Slc39a2)solute carrier family 39 (zinc transporter), member 2⌘
R. norvegicusUniProtKB:Q5U1X7 · RGD:1310863 (Slc39a3)solute carrier family 39 (zinc transporter), member 3⌘
S. cerevisiaeUniProtKB:P32804 · SGD:S000003224 (YGL255W · ZRT1)High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake⌘
S. cerevisiaeUniProtKB:Q12436 · SGD:S000004120 (YLR130C · ZRT2)Low-affinity zinc transporter of the plasma membrane⌘
S. pombeUniProtKB:O94639 · GeneDB_Spombe:SPBC16D10.06 (SPBC16D10.06 · zrt1)ZIP zinc transporter Zrt1⌘
ProteinPublicationCurator Notes
UniProtKB:Q12436 · SGD:S000004120PMID:11706025 Moreau S, et al. GmZIP1 encodes a symbiosis-specific zinc transporter in soybean. J Biol Chem. 2002 Feb 15;277(7):4738-46.The A. thaliana proteins AT4G19690.1 and AT4G19690.2 complement a homologous mutation in S. cerevisiae. Arabidopsis IRT1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:11706025 Moreau S, et al. GmZIP1 encodes a symbiosis-specific zinc transporter in soybean. J Biol Chem. 2002 Feb 15;277(7):4738-46.The A. thaliana proteins AT4G19690.1 and AT4G19690.2 complement a homologous mutation in S. cerevisiae. Arabidopsis IRT1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:11706025 Moreau S, et al. GmZIP1 encodes a symbiosis-specific zinc transporter in soybean. J Biol Chem. 2002 Feb 15;277(7):4738-46.The G. max protein GmZIP1 complements a homologous mutation in S. cerevisiae. Soybean ZIP1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:11706025 Moreau S, et al. GmZIP1 encodes a symbiosis-specific zinc transporter in soybean. J Biol Chem. 2002 Feb 15;277(7):4738-46.The G. max protein GmZIP1 complements a homologous mutation in S. cerevisiae. Soybean ZIP1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:10394943 Korshunova YO, et al. The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range. Plant Mol Biol. 1999 May;40(1):37-44.The A. thaliana proteins AT4G19690.1 and AT4G19690.2 complement a homologous mutation in S. cerevisiae. Arabidopsis IRT1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:10394943 Korshunova YO, et al. The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range. Plant Mol Biol. 1999 May;40(1):37-44.The A. thaliana proteins AT4G19690.1 and AT4G19690.2 complement a homologous mutation in S. cerevisiae. Arabidopsis IRT1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:11035780 Rogers EE, et al. Altered selectivity in an Arabidopsis metal transporter. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12356-60.The A. thaliana proteins AT4G19690.1 and AT4G19690.2 complement a homologous mutation in S. cerevisiae. A. thaliana IRT1 complements a yeast zrt1 zrt2 double mutant; IRT1 is also shown to transport iron, manganese, and cadmium.
UniProtKB:P32804 · SGD:S000003224PMID:11035780 Rogers EE, et al. Altered selectivity in an Arabidopsis metal transporter. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12356-60.The A. thaliana proteins AT4G19690.1 and AT4G19690.2 complement a homologous mutation in S. cerevisiae. A. thaliana IRT1 complements a yeast zrt1 zrt2 double mutant; IRT1 is also shown to transport iron, manganese, and cadmium.
UniProtKB:Q12436 · SGD:S000004120PMID:15509557 Mathews WR, et al. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J Biol Chem. 2005 Jan 7;280(1):787-95.The A. thaliana protein AT3G12750.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:15509557 Mathews WR, et al. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J Biol Chem. 2005 Jan 7;280(1):787-95.The A. thaliana protein AT3G12750.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:15509557 Mathews WR, et al. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J Biol Chem. 2005 Jan 7;280(1):787-95.The D. melanogaster protein CG6817-PA complements a homologous mutation in S. cerevisiae. Drosophila fear-of-intimacy (FOI) complements a yeast zrt1 zrt2 double mutant and functions as a zinc transporter in human HEK293 cells.
UniProtKB:P32804 · SGD:S000003224PMID:15509557 Mathews WR, et al. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J Biol Chem. 2005 Jan 7;280(1):787-95.The D. melanogaster protein CG6817-PA complements a homologous mutation in S. cerevisiae. Drosophila fear-of-intimacy (FOI) complements a yeast zrt1 zrt2 double mutant and functions as a zinc transporter in human HEK293 cells.
UniProtKB:P32804 · SGD:S000003224PMID:11997387 Huang L, et al. Functional characterization of a novel mammalian zinc transporter, ZnT6. J Biol Chem. 2002 Jul 19;277(29):26389-95.The M. musculus protein Q8BJM5 was expressed in S. cerevisiae, but complementation was not directly tested. Overexpression of mouse ZnT6 exacerbates the zinc deficiency of a zrt1 mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:14648120 Cohen CK, et al. Kinetic properties of a micronutrient transporter from Pisum sativum indicate a primary function in Fe uptake from the soil. Planta. 2004 Mar;218(5):784-92.The P. sativum protein RIT1 complements a homologous mutation in S. cerevisiae. Pea RIT1 complements a zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:14648120 Cohen CK, et al. Kinetic properties of a micronutrient transporter from Pisum sativum indicate a primary function in Fe uptake from the soil. Planta. 2004 Mar;218(5):784-92.The P. sativum protein RIT1 complements a homologous mutation in S. cerevisiae. Pea RIT1 complements a zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:9618566 Grotz N, et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7220-4.The A. thaliana protein AT5G59520.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP2 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:9618566 Grotz N, et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7220-4.The A. thaliana protein AT5G59520.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP2 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:9618566 Grotz N, et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7220-4.The A. thaliana protein AT2G32270.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP3 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:9618566 Grotz N, et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7220-4.The A. thaliana protein AT2G32270.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP3 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:Q12436 · SGD:S000004120PMID:9618566 Grotz N, et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7220-4.The A. thaliana protein AT3G12750.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP1 complements a yeast zrt1 zrt2 double mutant.
UniProtKB:P32804 · SGD:S000003224PMID:9618566 Grotz N, et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7220-4.The A. thaliana protein AT3G12750.1 complements a homologous mutation in S. cerevisiae. Arabidopsis ZIP1 complements a yeast zrt1 zrt2 double mutant.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
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