P-POD: Princeton Protein Orthology Database: GO3/Nens295

This family has 44 members: 4 Arabidopsis thaliana, 2 Caenorhabditis elegans, 3 Danio rerio, 6 Dictyostelium discoideum, 8 Drosophila melanogaster, 1 Escherichia coli, 3 Gallus gallus, 5 Homo sapiens, 5 Mus musculus, 5 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens295
44 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2159143 (MAC12_38 · AT5G13980 · MAC12.38) · NCBI:NP_851037.2⌘
A. thalianaNCBI:NP_196999.1 · TAIR:locus:2147855 (ATGMII · GMII · AT5G14950 · F2G14_70 · F2G14.70)GOLGI ALPHA-MANNOSIDASE II⌘
A. thalianaNCBI:NP_201416.1 · TAIR:locus:2156857 (AT5G66150 · K2A18.23 · K2A18_23)⌘
A. thalianaNCBI:NP_189306.1 · TAIR:locus:2090817 (AT3G26720 · MLJ15.19)⌘
C. elegansWB:WBGene00018877 (F55D10.1 · aman-1) · UniProtKB:Q20829⌘
C. elegansWB:WBGene00010284 (F58H1.1 · aman-2) · UniProtKB:Q2PJ74⌘
D. rerioENSEMBL:ENSDARP00000086327
D. rerioENSEMBL:ENSDARG00000059669 · UniProtKB:A2CED8
D. rerioZFIN:ZDB-GENE-050327-52 (zgc:110815) · UniProtKB:Q58EM3⌘
D. discoideumdictyBase:DDB_G0292206 (manA · alpha-mannosidase) · UniProtKB:P34098⌘
D. discoideumdictyBase:DDB_G0278259 (alpha-mannosidase · manB) · UniProtKB:Q54YF7⌘
D. discoideumdictyBase:DDB_G0268994 (manC · alpha-mannosidase) · UniProtKB:Q55ER0⌘
D. discoideumdictyBase:DDB_G0278653 (manD · alpha-mannosidase) · UniProtKB:Q54YC4⌘
D. discoideumdictyBase:DDB_G0278651 (manE · alpha-mannosidase) · UniProtKB:Q1ZXI8⌘
D. discoideumdictyBase:DDB_G0287577 (alpha-mannosidase · manG) · UniProtKB:Q54K67⌘
D. melanogasterUniProtKB:Q24451 · FB:FBgn0011740 (CG18802 · GmII · Man · alpha-Man-II · DM-GII.1 · GMII · MAN-2 · CG18474 · CG8139 · dGMII)Golgi mannosidase II · Golgi Man II · alpha-mannosidase 2 · mannosidase II · alpha-mannosidase II · alpha Mannosidase II⌘
D. melanogasterFB:FBgn0032069 (CG9468) · UniProtKB:Q8MS44⌘
D. melanogasterFB:FBgn0032066 (CG9463) · UniProtKB:Q8SYY1⌘
D. melanogasterUniProtKB:Q9VF33 · FB:FBgn0026616 (GTD#24/1 · alpha-M-II · CG4606 · alpha-Man-IIb · alpha-mannosidase · alpha-D-mannosidase · Man'ase · DM-GII.2)alpha-mannosidase 2 · mannosidase II⌘
D. melanogasterFB:FBgn0027611 (BcDNA:GH02419 · CG6206) · UniProtKB:Q9VKV1⌘
D. melanogasterFB:FBgn0032253 (CG5322) · UniProtKB:Q9VKV2⌘
D. melanogasterFB:FBgn0032068 (CG9466) · UniProtKB:Q9VLI0⌘
D. melanogasterFB:FBgn0032067 (CG9465) · UniProtKB:Q9VLI1⌘
E. coliUniProtKB:P54746 · ECOLI:EG13236-MONOMER (ECK0720 · MngB · b0732 · ybgG · alpha-mannosidase · mngB)⌘
G. gallusNCBI:XP_420805 · ENTREZ:422859
G. gallusNCBI:XP_001233608 · ENTREZ:415585
G. gallusUniProtKB:Q5F3F8 (RCJMB04_18f23 · Q5F3F8 · IPI00601126) · ENTREZ:415306⌘
H. sapiensENSEMBL:ENSG00000112893 · UniProtKB:Q16706 (MANA2 · MA2A1_HUMAN · MAN2A1 · IPI00003802 · Q16706)Alpha-mannosidase 2⌘
H. sapiensENSEMBL:ENSG00000196547 · UniProtKB:P49641 (MAN2A2 · IPI00220303 · IPI00027703 · MANA2X · MA2A2_HUMAN · P49641)Alpha-mannosidase 2x⌘
H. sapiensENSEMBL:ENSG00000104774 · UniProtKB:O00754 (MANB · MAN2B1 · MA2B1_HUMAN · LAMAN · IPI00012989 · O00754)Lysosomal alpha-mannosidase⌘
H. sapiensENSEMBL:ENSG00000013288 · UniProtKB:Q9Y2E5 (MA2B2_HUMAN · IPI00328488 · MAN2B2 · Q9Y2E5 · IPI00604401 · KIAA0935)Epididymis-specific alpha-mannosidase⌘
H. sapiensENSEMBL:ENSG00000140400 · UniProtKB:Q9NTJ4 (IPI00783434 · MANA1 · MANA · MA2C1_HUMAN · MAN2C1 · Q9NTJ4)Alpha-mannosidase 2C1⌘
M. musculusNCBI:NP_766491 · MGI:MGI:2150656 (MX · Man2a2)mannosidase 2, alpha 2 · alpha mannosidase IIx⌘
M. musculusUniProtKB:P27046 · MGI:MGI:104669 (Mana2 · Man2a1 · Mana-2 · Map-2)mannosidase 2, alpha 1⌘
M. musculusUniProtKB:O09159 · MGI:MGI:107286 (Man2b1)lysosomal alpha-mannosidase · mannosidase 2, alpha B1⌘
M. musculusUniProtKB:O54782 · MGI:MGI:1195262 (Man2b2)mannosidase 2, alpha B2 · 135 kDa alpha-D-mannosidase⌘
M. musculusUniProtKB:Q91W89 · MGI:MGI:1920994 (Man2c1)mannosidase, alpha, class 2C, member 1⌘
R. norvegicusNCBI:XP_218816 · RGD:1310238
R. norvegicusUniProtKB:P28494 (Mana2 · IPI00367150 · Man2a1 · MA2A1_RAT · P28494) · RGD:3038 (Man2a1)Alpha-mannosidase 2 · mannosidase, alpha, class 2A, member 1⌘⌘
R. norvegicusUniProtKB:P21139 · RGD:628787 (Man2c1)mannosidase, alpha, class 2C, member 1⌘
R. norvegicusUniProtKB:Q6P762 · RGD:3039 (Man2b1)mannosidase, alpha, class 2B, member 1⌘
R. norvegicusRGD:1308840 · UniProtKB:Q7TP34
S. cerevisiaeUniProtKB:P22855 · SGD:S000003124 (YGL156W · AMS1)Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation⌘
S. pombeGeneDB_Spombe:SPAC513.05 (SPAC513.05 · ams1 · alpha-mannosidase) · UniProtKB:Q9UT61⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000104774 · UniProtKB:O00754#248500 MANNOSIDOSIS, ALPHA B, LYSOSOMAL;;ALPHA-MANNOSIDOSIS;;ALPHA-MANNOSIDOSIS, TYPE I;;LYSOSOMAL ALPHA-D-MANNOSIDASE DEFICIENCY;;ALPHA-MANNOSIDASE B DEFICIENCYALPHA-MANNOSIDOSIS, TYPE II, INCLUDED
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu