This family has 12 members: 2 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | TAIR:locus:2016354 (F19K16_10 · AT1G79940 · F19K16.10 · ATERDJ2A) · NCBI:NP_178112.2 |  | |
| A. thaliana | NCBI:NP_567621.1 · TAIR:locus:2127373 (ATERDJ2B · AT4G21180 · F7J7.120 · F7J7_120) | | |
| C. elegans | WB:WBGene00001047 (dnj-29 · Y63D3A.6) · UniProtKB:Q9U1V9 | | |
| D. rerio | UniProtKB:Q6DGY6 · ZFIN:ZDB-GENE-040718-328 (sec63) | SEC63-like (S. cerevisiae) | |
| D. discoideum | dictyBase:DDB_G0286131 (DDB_G0286131) · UniProtKB:Q54M91 | | |
| D. melanogaster | FB:FBgn0035771 (peg · anon-WO0118547.333 · CG8583 · sec63) · UniProtKB:Q9VS57 | | |
| G. gallus | NCBI:XP_419802 · ENTREZ:421774 | ||
| H. sapiens | ENSEMBL:ENSG00000025796 · UniProtKB:Q9UGP8 (Q9UGP8 · IPI00218922 · SEC63_HUMAN · SEC63 · SEC63L) | Translocation protein SEC63 homolog | |
| M. musculus | UniProtKB:Q8VHE0 · MGI:MGI:2155302 (Sec63) | SEC63-like (S. cerevisiae) | |
| R. norvegicus | NCBI:NP_001101107 · RGD:1304984 | ||
| S. cerevisiae | UniProtKB:P14906 · SGD:S000005780 (SEC63 · PTL1 · YOR254C) | Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p) | |
| S. pombe | UniProtKB:Q9HGN7 · GeneDB_Spombe:SPBC36B7.03 (sec63 · SPBC36B7.03) | ER protein translocation subcomplex subunit Sec63 | |
| Protein | Publication | Curator Notes | |
|---|---|---|---|
| UniProtKB:P14906 · SGD:S000005780 |  16889384 Zhang W, et al. Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins. Biotechnol Prog. 2006 Jul-Aug;22(4):1090-5. | The S. cerevisiae protein SEC63 was expressed in P. pastoris, but complementation was not directly tested. This paper shows heterologous overexpression of S. cerevisiae SEC63 in P. pastoris. |
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| OMIM (1) | |
|---|---|
| ENSEMBL:ENSG00000025796 · UniProtKB:Q9UGP8 | #174050 POLYCYSTIC LIVER DISEASE; PCLD |