P-POD: Princeton Protein Orthology Database: GO3/Nens2311

This family has 13 members: 1 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 2 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens2311
13 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_179770.1 · TAIR:locus:2052469 (ATRNR1 · CLS8 · RNR1 · R1 · F7D8_11 · F7D8.11 · AT2G21790)RIBONUCLEOTIDE REDUCTASE LARGE SUBUNIT 1 · RIBONUCLEOTIDE REDUCTASE 1 · CRINKLY LEAVES 8⌘
C. elegansWB:WBGene00004391 (T23G5.1 · rnr-1) · UniProtKB:Q03604 (T23G5.1 · RIR1_CAEEL · rnr-1)Ribonucleoside-diphosphate reductase large subunit⌘⌘
D. rerioUniProtKB:P79732 · ZFIN:ZDB-GENE-990415-247 (rrm1)ribonucleotide reductase M1 polypeptide⌘
D. discoideumUniProtKB:Q54Q71 · dictyBase:DDB_G0284071 (rnrA · RNR)ribonucleoside-diphosphate reductase, ribonucleotide reductase large subunit⌘
D. melanogasterUniProtKB:P48591 · FB:FBgn0011703 (RNR1 · RntL · CG5371 · RnrM1 · l(2)k06709 · RnrL · DmRNR1)Ribonucleoside diphosphate reductase M1 subunit · Ribonucleoside diphosphate reductase large subunit · ribonucleoside-diphosphate reductase large subunit⌘
E. coliUniProtKB:P00452 · ECOLI:NRDA-MONOMER (b2234 · DnaF · NrdA · nrdA · B2234 · dnaF · ECK2226)ribonucleoside diphosphate reductase 1 · alpha subunit⌘
G. gallusENTREZ:419081 · UniProtKB:Q5ZM69 (Q5ZM69 · IPI00580561 · RCJMB04_2p9)Ribonucleoside-diphosphate reductase⌘
H. sapiensENSEMBL:ENSG00000167325 · UniProtKB:P23921 (IPI00013871 · P23921 · RR1 · RRM1 · RIR1_HUMAN)Ribonucleoside-diphosphate reductase large subunit⌘
M. musculusUniProtKB:P07742 · MGI:MGI:98180 (Rrm1 · RnrM1)ribonucleotide reductase M1⌘
R. norvegicusUniProtKB:Q5U2Q5 · RGD:1598288 (Rrm1-ps1)ribonucleotide reductase M1, pseudogene 1⌘
S. cerevisiaeUniProtKB:P21524 · SGD:S000000872 (SDS12 · RNR1 · YER070W · CRT7 · RIR1)One of two large regulatory subunits of ribonucleotide-diphosphate reductase⌘
S. cerevisiaeUniProtKB:P21672 · SGD:S000001328 (RNR3 · DIN1 · RIR3 · YIL066C)One of two large regulatory subunits of ribonucleotide-diphosphate reductase⌘
S. pombeUniProtKB:P36602 · GeneDB_Spombe:SPAC1F7.05 (cdc22 · SPAC1F7.05)ribonucleoside reductase large subunit Cdc22⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
SGD Disease Papers (1)
UniProtKB:P21524 · SGD:S000000872PMID:18588281 Cappellacci L, et al. (2008) Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N(6)-Substituted 3'-C-Methyladenosine Derivatives. J Med Chem 51(14):4260-4269
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu