This family has 53 members: 10 Arabidopsis thaliana, 2 Caenorhabditis elegans, 4 Danio rerio, 6 Dictyostelium discoideum, 5 Drosophila melanogaster, 5 Gallus gallus, 6 Homo sapiens, 6 Mus musculus, 5 Rattus norvegicus, 2 Saccharomyces cerevisiae, 2 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | TAIR:locus:504956457 (AT5G21900) · NCBI:NP_680178.1 |  | |
| A. thaliana | NCBI:NP_567916.1 · TAIR:locus:2125939 (F4I10.140 · F4I10_140 · AT4G33210) | | |
| A. thaliana | NCBI:NP_567069.1 · TAIR:locus:2076376 (F14P22.120 · AT3G58530) | | |
| A. thaliana | NCBI:NP_197725.1 · TAIR:locus:2166978 (AT5G23340 · MKD15_20 · MKD15.20) | | |
| A. thaliana | NCBI:NP_568502.1 · TAIR:locus:2143320 (AT5G27920 · F15F15.2) | | |
| A. thaliana | NCBI:NP_567467.1 · TAIR:locus:505006471 (AT4G15475) | | |
| A. thaliana | NCBI:NP_178661.2 · TAIR:locus:2051542 (F5K7.20 · AT2G06040 · F5K7_20) | | |
| A. thaliana | NCBI:NP_568094.2 · TAIR:locus:2149805 (AT5G01720 · F7A7.240 · F7A7_240) | | |
| A. thaliana | NCBI:NP_565597.1 · TAIR:locus:2040105 (F13B15_15 · EBF1 · FBL6 · AT2G25490 · F13B15.15) | EIN3-BINDING F BOX PROTEIN 1 | |
| A. thaliana | NCBI:NP_197917.1 · TAIR:locus:2145512 (AT5G25350 · F18G18.90 · EBF2 · F18G18_90) | EIN3-BINDING F BOX PROTEIN 2 | |
| C. elegans | WB:WBGene00015350 · UniProtKB:P34284 | ||
| C. elegans | WB:WBGene00011331 · UniProtKB:Q21768 | ||
| D. rerio | ZFIN:ZDB-GENE-061215-122 (zgc:158346) · UniProtKB:A1A5X2 | | |
| D. rerio | UniProtKB:Q5RH13 · ZFIN:ZDB-GENE-030131-3556 (fbxl14) | F-box and leucine-rich repeat protein 14b | |
| D. rerio | ZFIN:ZDB-GENE-030925-12 · UniProtKB:Q6PBJ7 | ||
| D. rerio | UniProtKB:Q6TGX5 · ZFIN:ZDB-GENE-030131-5920 (fbxl14a) | F-box and leucine-rich repeat protein 14a | |
| D. discoideum | UniProtKB:Q54JI4 · dictyBase:DDB_G0288031 (DDB_G0288031) | leucine-rich repeat-containing protein (LRR), villin headpiece (VHP) domain-containing protein, putative actin binding protein | |
| D. discoideum | dictyBase:DDB_G0287415 (DDB_G0287415) · UniProtKB:Q54KC6 | | |
| D. discoideum | dictyBase:DDB_G0285177 (DDB_G0285177) · UniProtKB:Q54NL3 | | |
| D. discoideum | dictyBase:DDB_G0278145 (DDB_G0278145) · UniProtKB:Q54YP2 | | |
| D. discoideum | UniProtKB:Q551N7 · dictyBase:DDB_G0276529 (DDB_G0276529) | Similar to Dictyostelium discoideum (Slime mold). Non-receptor tyrosine kinase spore lysis A (EC 2.7.1.112) (Tyrosine-protein kinase 1). | |
| D. discoideum | dictyBase:DDB_G0275117 · UniProtKB:Q8T2T4 | ||
| D. melanogaster | FB:FBgn0033639 (CG9003) · UniProtKB:A1Z8M8 | | |
| D. melanogaster | FB:FBgn0033337 · UniProtKB:Q7K0V7 | ||
| D. melanogaster | FB:FBgn0038385 · UniProtKB:Q9VF10 | ||
| D. melanogaster | FB:FBgn0038202 · UniProtKB:Q9VFN3 | ||
| D. melanogaster | UniProtKB:Q9W214 · FB:FBgn0020257 (Ppa · I-55 · CG9952 · ppa) | partner of paired | |
| G. gallus | NCBI:XP_001235091 · ENTREZ:771869 | ||
| G. gallus | NCBI:XP_425498 · ENTREZ:427926 | ||
| G. gallus | NCBI:XP_415966 · ENTREZ:417721 | ||
| G. gallus | NCBI:XP_426048 · ENTREZ:428492 | ||
| G. gallus | NCBI:XP_418823 · ENTREZ:420722 | ||
| H. sapiens | ENSEMBL:ENSG00000153558 · UniProtKB:Q9UKC9 (FBXL2 · FBL3 · FBL2 · FBXL2_HUMAN · IPI00296850 · Q9UKC9) | F-box/LRR-repeat protein 2 | |
| H. sapiens | ENSEMBL:ENSG00000183580 · UniProtKB:Q9UJT9 (FBXL7 · FBXL7_HUMAN · FBL7 · KIAA0840 · Q9UJT9 · FBL6 · IPI00017566) | F-box/LRR-repeat protein 7 | |
| H. sapiens | ENSEMBL:ENSG00000161040 · UniProtKB:Q8NEE6 (Q8NEE6 · IPI00554466 · IPI00554446 · IPI00171183 · FBXL13 · FBL13 · IPI00554608 · FXL13_HUMAN) | F-box/LRR-repeat protein 13 | |
| H. sapiens | ENSEMBL:ENSG00000171823 · UniProtKB:Q8N1E6 (FXL14_HUMAN · FBL14 · Q8N1E6 · IPI00166145 · FBXL14) | F-box/LRR-repeat protein 14 | |
| H. sapiens | ENSEMBL:ENSG00000108306 · UniProtKB:Q96IG2 (Q96IG2 · FBXL20 · FXL20_HUMAN · FBL2 · IPI00174757 · IPI00655936) | F-box/LRR-repeat protein 20 | |
| H. sapiens | ENSEMBL:ENSG00000125122 · UniProtKB:Q8WV35 (LRC29_HUMAN · FBL9 · LRRC29 · Q8WV35 · FBXL9 · IPI00073186) | Leucine-rich repeat-containing protein 29 | |
| M. musculus | NCBI:NP_803232 · MGI:MGI:2443262 | ||
| M. musculus | UniProtKB:Q8BH16 · MGI:MGI:1919429 (Fbl3 · Fbxl2) | F-box and leucine-rich repeat protein 2 | |
| M. musculus | UniProtKB:Q5BJ29 · MGI:MGI:3052506 (Fbxl7 · FBL7 · Fbl6) | F-box and leucine-rich repeat protein 7 | |
| M. musculus | UniProtKB:Q8CDU4 · MGI:MGI:2443416 (Fbxl13) | F-box and leucine-rich repeat protein 13 | |
| M. musculus | UniProtKB:Q8BID8 · MGI:MGI:2141676 (Fbxl14) | F-box and leucine-rich repeat protein 14 | |
| M. musculus | UniProtKB:Q9CZV8 · MGI:MGI:1919444 (Fbl2 · Fbxl20 · Scrapper · Scr · C86145) | F-box and leucine-rich repeat protein 20 | |
| R. norvegicus | NCBI:XP_232330 · RGD:1305523 | ||
| R. norvegicus | NCBI:XP_343496 · RGD:1562243 (Fbxl2) | F-box and leucine-rich repeat protein 2 | |
| R. norvegicus | NCBI:XP_342205 · RGD:1305813 (Fbxl7) | F-box and leucine-rich repeat protein 7 | |
| R. norvegicus | NCBI:XP_001075557 · RGD:1593150 | ||
| R. norvegicus | UniProtKB:Q5PQK0 · RGD:1642425 (Fbxl13) | F-box and leucine-rich repeat protein 13 | |
| S. cerevisiae | UniProtKB:P24814 · SGD:S000003850 (YJR090C · CAT80 · SSU2 · GRR1 · SDC1 · COT2) | F-box protein component of the SCF ubiquitin-ligase complex | |
| S. cerevisiae | UniProtKB:P06779 · SGD:S000003813 (YJR052W · RAD7) | Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair | |
| S. pombe | UniProtKB:O74783 · GeneDB_Spombe:SPBC25B2.11 (SPBC25B2.11 · pof2) | F-box protein Pof2 | |
| S. pombe | UniProtKB:O74999 · GeneDB_Spombe:SPCC330.02 (SPCC330.02 · rhp7 · SPCC613.14) | Rad7 homolog Rhp7 | |
| Protein | Publication | Curator Notes | |
|---|---|---|---|
| UniProtKB:P24814 · SGD:S000003850 |  12008900 Thelander M, et al. Cloning by pathway activation in yeast: identification of an Arabidopsis thaliana F-box protein that can turn on glucose repression. Plant Mol Biol. 2002 May;49(1):69-79. | The A. thaliana protein AT4G03190.1 does not complement a homologous mutation in S. cerevisiae. | |
| UniProtKB:P24814 · SGD:S000003850 | 16824096 Krappmann S, et al. The Aspergillus nidulans F-box protein GrrA links SCF activity to meiosis. Mol Microbiol. 2006 Jul;61(1):76-88. | The A. nidulans protein GrrA complements a homologous mutation in S. cerevisiae. This paper shows functional complementation of an S. cerevisiae grr1 null mutant by overexpression of A. nidulans GrrA. |
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |