P-POD: Princeton Protein Orthology Database: GO3/Nens20165

This family has 2 members: 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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2 members.
OrganismProtein (Synonyms)DescriptionAmiGO
S. cerevisiaeUniProtKB:P22146 · SGD:S000004924 (GGP1 · YMR307W · GAS1 · CWH52)Beta-1,3-glucanosyltransferase, required for cell wall assembly⌘
S. pombeUniProtKB:Q9P378 · GeneDB_Spombe:SPAC19B12.02c (gas1 · SPAC19B12.02c)1,3-beta-glucanosyltransferase Gas1⌘
ProteinPublicationCurator Notes
UniProtKB:P22146 · SGD:S000004924PMID:17020547 Marx H, et al. Cloning, disruption and protein secretory phenotype of the GAS1 homologue of Pichia pastoris. FEMS Microbiol Lett. 2006 Nov;264(1):40-7.The P. pastoris protein GAS1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P22146 · SGD:S000004924PMID:15916615 Mouyna I, et al. Deletion of GEL2 encoding for a beta(1-3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus. Mol Microbiol. 2005 Jun;56(6):1675-88.The A. fumigatus protein GEL2 complements a homologous mutation in S. cerevisiae. A. fumigatus GEL2 complements a yeast gas1 null mutant, and so does its homolog GEL1. Both A. fumigatus GEL1 and GEL2 have the same glycosylphosphatidylinositol-anchored glucanosyltransferase enzymatic activity.
UniProtKB:P22146 · SGD:S000004924PMID:10809732 Mouyna I, et al. Glycosylphosphatidylinositol-anchored glucanosyltransferases play an active role in the biosynthesis of the fungal cell wall. J Biol Chem. 2000 May 19;275(20):14882-9.The A. fumigatus protein GEL1 complements a homologous mutation in S. cerevisiae. A. fumigatus GEL1 complements a yeast gas1 null mutant, and so does its homolog GEL2. Both A. fumigatus GEL1 and GEL2 have the same glycosylphosphatidylinositol-anchored glucanosyltransferase enzymatic activity.
DescriptionSuffix
Sequences in this family.fasta
SGD Disease Papers (1)
UniProtKB:P22146 · SGD:S000004924PMID:18434410 Luallen RJ, et al. (2008) An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies. J Virol 82(13):6447-57
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