P-POD: Princeton Protein Orthology Database: GO3/Nens1885

This family has 15 members: 1 Arabidopsis thaliana, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 2 Homo sapiens, 2 Mus musculus, 2 Rattus norvegicus, 3 Saccharomyces cerevisiae, 2 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens1885
15 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_197467.1 · TAIR:locus:2183224 (T29J13.80 · ATS1P · AT5G19660 · T29J13_80 · S1P · ATSBT6.1)SITE-1 PROTEASE⌘
D. rerioUniProtKB:Q6X1U1 · ZFIN:ZDB-GENE-030131-4909 (mbtps1)membrane-bound transcription factor protease, site 1⌘
D. discoideumUniProtKB:Q54SL5 · dictyBase:DDB_G0282397 (mbtps1)membrane-bound transcription factor peptidase, site 1, subtilase family protein⌘
D. melanogasterFB:FBgn0037105 (CG7169 · dS1P · S1P) · UniProtKB:Q9VP10⌘
H. sapiensENSEMBL:ENSG00000140943 · UniProtKB:Q14703 (MBTP1_HUMAN · IPI00021569 · MBTPS1 · Q14703 · KIAA0091 · S1P · SKI1)Membrane-bound transcription factor site-1 protease⌘
H. sapiensENSEMBL:ENSG00000169174 · UniProtKB:Q8NBP7 (IPI00387168 · NARC1 · Q8NBP7 · PCSK9_HUMAN · PSEC0052 · PCSK9 · IPI00387169)Proprotein convertase subtilisin/kexin type 9⌘
M. musculusUniProtKB:Q9WTZ2 · MGI:MGI:1927235 (SKI-1 · Mbtps1 · S1P)site-1 protease · subtilisin/kexin isozyme-1 · membrane-bound transcription factor peptidase, site 1⌘
M. musculusUniProtKB:Q80W65 · MGI:MGI:2140260 (IPI00377933 · Narc1 · Pcsk9 · PCSK9_MOUSE)proprotein convertase subtilisin/kexin type 9⌘
R. norvegicusUniProtKB:Q9WTZ3 · RGD:70935 (Mbtps1)membrane-bound transcription factor peptidase, site 1⌘
R. norvegicusUniProtKB:P59996 · RGD:728909 (Pcsk9)proprotein convertase subtilisin/kexin type 9⌘
S. cerevisiaeUniProtKB:P09232 · SGD:S000000786 (PRB1 · YEL060C · CVT1)Vacuolar proteinase B (yscB), a serine protease of the subtilisin family⌘
S. cerevisiaeUniProtKB:P25381 · SGD:S000000641 (YCR045C · OSW3 · RRT12)Putative protein of unknown function⌘
S. cerevisiaeUniProtKB:P25036 · SGD:S000005529 (YOR003W · YSP3)Putative precursor to the subtilisin-like protease III⌘
S. pombeUniProtKB:P40903 · GeneDB_Spombe:SPAC4A8.04 (prb1 · SPAC4A8.04 · isp6)vacuolar serine protease Isp6⌘
S. pombeUniProtKB:Q9UTS0 · GeneDB_Spombe:SPAC1006.01 (SPAC1006.01 · psp3)serine protease Psp3⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (2)
ENSEMBL:ENSG00000169174 · UniProtKB:Q8NBP7#603776 HYPERCHOLESTEROLEMIA, AUTOSOMAL DOMINANT, 3; HCHOLA3;;FH3
UniProtKB:P09232 · SGD:S000000786+607786 PROPROTEIN CONVERTASE, SUBTILISIN/KEXIN-TYPE, 9; PCSK9;;NEURAL APOPTOSIS-REGULATED CONVERTASE 1; NARC1LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS1, INCLUDED; LDLCQ1, INCLUDED
SGD Disease Papers (1)
UniProtKB:P09232 · SGD:S000000786PMID:12923060 Roberts BT and Wickner RB (2003) Heritable activity: a prion that propagates by covalent autoactivation. Genes Dev 17(17):2083-7
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