This family has 17 members: 2 Arabidopsis thaliana, 1 Caenorhabditis elegans, 2 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 2 Homo sapiens, 1 Mus musculus, 3 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | NCBI:NP_179713.1 · TAIR:locus:2047072 (F26H11.7 · TIM · F26H11_7 · AT2G21170) | TRIOSEPHOSPHATE ISOMERASE |  |
| A. thaliana | NCBI:NP_191104.1 · TAIR:locus:2099906 (TPI · T22E16.100 · AT3G55440 · ATCTIMC) | triosephosphate isomerase · TRIOSEPHOSPHATE ISOMERASE · CYTOSOLIC TRIOSE PHOSPHATE ISOMERASE | |
| C. elegans | WB:WBGene00006601 (Y17G7B.7 · tpi-1) · UniProtKB:Q10657 | | |
| D. rerio | UniProtKB:Q1MTI4 · ZFIN:ZDB-GENE-020416-3 (tpi1a) | triosephosphate isomerase 1a | |
| D. rerio | UniProtKB:Q90XG0 · ZFIN:ZDB-GENE-020416-4 (tpi1b) | triosephosphate isomerase 1b | |
| D. discoideum | UniProtKB:Q869R8 · dictyBase:DDB_G0274471 (TPI1 · tpiA) | triose phosphate isomerase, triosephosphate isomerase | |
| D. melanogaster | UniProtKB:P29613 · FB:FBgn0086355 (TPIS · TPI · sgk · wstd · sugarkill · tpi · Tpi · ND14 · CG2171) | wasted away · Triose phosphate isomerase · triose phosphate isomerase · Triosephosphate isomerase · Neurodegeneration 14 | |
| E. coli | UniProtKB:P0A858 · ECOLI:TPI-MONOMER (B3919 · tpi · b3919 · TpiA · Tpi · ECK3911 · tpiA) | triosephosphate isomerase · triose phosphate isomerase · triose phosphate isomerase monomer | |
| G. gallus | ENTREZ:396435 · UniProtKB:P00940 (P00940 · TPIS_CHICK · TPI1 · IPI00582452) | Triosephosphate isomerase | |
| H. sapiens | ENSEMBL:ENSG00000212826 · UniProtKB:Q7Z6K2 (IPI00175344 · Q7Z6K2 · TPISL_HUMAN · IPI00844224) | Putative triosephosphate isomerase-like protein LOC286016 | |
| H. sapiens | ENSEMBL:ENSG00000111669 · UniProtKB:P60174 (TPI · TPIS_HUMAN · P60174 · IPI00451401 · TPI1 · IPI00465028) | Triosephosphate isomerase | |
| M. musculus | UniProtKB:P17751 · MGI:MGI:98797 (Tpi1 · Tpi-1) | triosephosphate isomerase 1 | |
| R. norvegicus | NCBI:XP_574007 · RGD:1563601 (RGD1563601) | similar to Tpi1 protein | |
| R. norvegicus | UniProtKB:P48500 · RGD:3896 (Tpi1) | triosephosphate isomerase 1 | |
| R. norvegicus | UniProtKB:Q6SA19 · RGD:1560534 (LOC500959) | triosephosphate isomerase | |
| S. cerevisiae | UniProtKB:P00942 · SGD:S000002457 (YDR050C · TPI1) | Triose phosphate isomerase, abundant glycolytic enzyme | |
| S. pombe | UniProtKB:P07669 · GeneDB_Spombe:SPCC24B10.21 (tpi · SPCC24B10.21 · tpi1) | triosephosphate isomerase | |
| Protein | Publication | Curator Notes | |
|---|---|---|---|
| UniProtKB:P00942 · SGD:S000002457 |  3521890 McKnight GL, et al. Nucleotide sequence of the triosephosphate isomerase gene from Aspergillus nidulans: implications for a differential loss of introns. Cell. 1986 Jul 4;46(1):143-7. | The A. nidulans protein tpiA complements a homologous mutation in S. cerevisiae. |
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| OMIM (1) | |
|---|---|
| UniProtKB:P00942 · SGD:S000002457 | +190450 TRIOSEPHOSPHATE ISOMERASE 1; TPI1;;TPITRIOSEPHOSPHATE ISOMERASE DEFICIENCY, INCLUDED |
| SGD Disease Papers (1) | |
| UniProtKB:P00942 · SGD:S000002457 | 12023819 Olah J, et al. (2002) Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease. Biochem Soc Trans 30(2):30-8 |