P-POD: Princeton Protein Orthology Database: GO3/Nens135

This family has 73 members: 14 Arabidopsis thaliana, 4 Caenorhabditis elegans, 10 Danio rerio, 6 Dictyostelium discoideum, 7 Drosophila melanogaster, 3 Gallus gallus, 7 Homo sapiens, 8 Mus musculus, 5 Rattus norvegicus, 5 Saccharomyces cerevisiae, 4 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens135
73 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2090467 · NCBI:NP_188382.1
A. thalianaNCBI:NP_188594.2 · TAIR:locus:2091221 (AT3G19600 · MMB12.7)⌘
A. thalianaNCBI:NP_200232.1 · TAIR:locus:2162565 (AT5G54210 · MDK4.3 · MDK4_3)⌘
A. thalianaNCBI:NP_196747.1 · TAIR:locus:2143019 (F14F18.30 · F14F18_30 · AT5G11860)⌘
A. thalianaNCBI:NP_001078764.1 · TAIR:locus:4010714056 (CPL4 · AT5G58003)C-TERMINAL DOMAIN PHOSPHATASE-LIKE 4⌘
A. thalianaNCBI:NP_175986.2 · TAIR:locus:2012010 (emb1860 · F14J16.15 · F14J16_15 · AT1G55900 · TIM50)embryo defective 1860⌘
A. thalianaNCBI:NP_001118664.1 · TAIR:locus:4515103095
A. thalianaNCBI:NP_180912.2 · TAIR:locus:2051164 (F4P9_31 · F4P9.31 · AT2G33540 · CPL3)C-TERMINAL DOMAIN PHOSPHATASE-LIKE 3⌘
A. thalianaNCBI:NP_173457.1 · TAIR:locus:2012943 (AT1G20320 · F14O10_8 · F14O10.8)⌘
A. thalianaNCBI:NP_175025.1 · TAIR:locus:2194656 (AT1G43600 · T10P12_14 · T10P12.14)⌘
A. thalianaNCBI:NP_175026.1 · TAIR:locus:2194666 (T10P12_15 · T10P12.15 · AT1G43610)⌘
A. thalianaNCBI:NP_178335.1 · TAIR:locus:2056256 (T16F16_8 · AT2G02290 · T16F16.8)⌘
A. thalianaNCBI:NP_197738.1 · TAIR:locus:2154458 (K19M13.10 · AT5G23470 · K19M13_10)⌘
A. thalianaNCBI:NP_178570.1 · TAIR:locus:2045044 (F1O13_6 · F1O13.6 · AT2G04930)⌘
C. elegansWB:WBGene00018474 (scpl-2 · F45E12.1) · UniProtKB:Q20432 (scpl-2 · DULRD_CAEEL · F45E12.1)Serine/threonine-protein phosphatase dullard homolog⌘⌘
C. elegansWB:WBGene00011897 (T21C9.12 · scpl-4) · UniProtKB:Q22647⌘
C. elegansWB:WBGene00007054 (B0379.4 · scpl-1) · UniProtKB:Q8T3G2⌘
C. elegansWB:WBGene00009479 (F36F2.6 · fcp-1) · UniProtKB:Q95QG8⌘
D. rerioZFIN:ZDB-GENE-061013-647 (zgc:154017) · UniProtKB:Q08BB5⌘
D. rerioZFIN:ZDB-GENE-030131-1809 (zgc:162265) · UniProtKB:A4QNX6⌘
D. rerioUniProtKB:Q5U395 · ZFIN:ZDB-GENE-041114-177 (dullard)dullard homolog⌘
D. rerioUniProtKB:Q5U3T3 · ZFIN:ZDB-GENE-041114-152 (dullardl)dullard homolog, like⌘
D. rerioUniProtKB:Q6NWD4 · ZFIN:ZDB-GENE-040426-1618 (timm50)translocase of inner mitochondrial membrane 50 homolog (yeast)⌘
D. rerioUniProtKB:Q08BV3 · ZFIN:ZDB-GENE-060929-488 (ctdsplb)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b⌘
D. rerioUniProtKB:Q0P4B2 · ZFIN:ZDB-GENE-060825-333 (ctdspla)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a⌘
D. rerioUniProtKB:Q6DRN5 · ZFIN:ZDB-GENE-040720-1 (ctdp1)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1⌘
D. rerioZFIN:ZDB-GENE-030131-184 (zgc:77714) · UniProtKB:Q6P3I6⌘
D. rerioZFIN:ZDB-GENE-050522-523 (zgc:113169) · UniProtKB:B0S5V5⌘
D. discoideumUniProtKB:Q9XYL0 · dictyBase:DDB_G0294376 (fcp1 · DG1148 · fcpA)putative CTD phosphatase⌘
D. discoideumUniProtKB:Q54GB2 · dictyBase:DDB_G0290365 (ctdspl2)CTD small phosphatase-like protein 2⌘
D. discoideumUniProtKB:Q54M72 · dictyBase:DDB_G0286145 (DDB_G0286145)dullard-like phosphatase domain containing protein⌘
D. discoideumUniProtKB:Q54M73 · dictyBase:DDB_G0286143 (DDB_G0286143)dullard-like phosphatase domain containing protein⌘
D. discoideumdictyBase:DDB_G0270196 · UniProtKB:Q55C70
D. discoideumUniProtKB:Q75JA4 · dictyBase:DDB_G0271690 (DDB_G0271690)PUTATIVE TFIIF-INTERACTING COMPONENT OF THE C-TERMINAL DOMAIN PHOSPHATASE⌘
D. melanogasterUniProtKB:Q9VRG7 · FB:FBgn0029067 (anon-WO03040301.167 · l(1)G0269 · CG1696 · BcDNA:LD08201)lethal (1) G0269⌘
D. melanogasterFB:FBgn0032971 · UniProtKB:Q9V9P3
D. melanogasterFB:FBgn0035124 · UniProtKB:Q9W0S3
D. melanogasterFB:FBgn0024978 · UniProtKB:Q9W4V8
D. melanogasterFB:FBgn0033322 (BEST:LP01468 · CG8584) · UniProtKB:Q7JY68⌘
D. melanogasterFB:FBgn0035026 (CG12252) · UniProtKB:Q8MQY2⌘
D. melanogasterFB:FBgn0036556 (CG5830) · UniProtKB:Q9VUX0⌘
G. gallusNCBI:XP_001233751 · ENTREZ:770413
G. gallusENTREZ:408252 · UniProtKB:Q9PTJ6 (CTDSL_CHICK · IPI00581375 · NIF · NFI1 · Q9PTJ6 · IPI00590439 · IPI00585014 · IPI00603791)CTD small phosphatase-like protein⌘
G. gallusENTREZ:415574 · UniProtKB:Q5F3Z7 (CTDSPL2 · RCJMB04_4a24 · Q5F3Z7 · IPI00579424 · CTSL2_CHICK)CTD small phosphatase-like protein 2⌘
H. sapiensENSEMBL:ENSG00000060069 · UniProtKB:Q9Y5B0 (CTDP1 · IPI00410257 · IPI00410258 · Q9Y5B0 · IPI00410256 · CTDP1_HUMAN · FCP1)RNA polymerase II subunit A C-terminal domain phosphatase⌘
H. sapiensENSEMBL:ENSG00000144579 · UniProtKB:Q9GZU7 (NIF3 · SCP1 · CTDS1_HUMAN · CTDSP1 · Q9GZU7 · IPI00009633 · NLIIF)Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1⌘
H. sapiensENSEMBL:ENSG00000175215 · UniProtKB:O14595 (SCP2 · OS4 · IPI00873134 · O14595 · CTDS2_HUMAN · NIF2 · CTDSP2)Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2⌘
H. sapiensENSEMBL:ENSG00000144677 · UniProtKB:O15194 (NIFL · C3orf8 · NIF1 · YA22 · SCP3 · IPI00024826 · IPI00454757 · CTDSL_HUMAN · O15194 · CTDSPL)CTD small phosphatase-like protein⌘
H. sapiensENSEMBL:ENSG00000137770 · UniProtKB:Q05D32 (CTSL2_HUMAN · IPI00871437 · CTDSPL2 · IPI00033054 · Q05D32 · HSPC129 · HSPC058)CTD small phosphatase-like protein 2⌘
H. sapiensENSEMBL:ENSG00000175826 · UniProtKB:O95476 (IPI00383704 · DULRD_HUMAN · O95476 · DULLARD)Serine/threonine-protein phosphatase dullard⌘
H. sapiensENSEMBL:ENSG00000105197 · UniProtKB:Q3ZCQ8 (TIM50_HUMAN · TIMM50 · IPI00418497 · IPI00656071 · Q3ZCQ8 · TIM50 · PRO1512)Mitochondrial import inner membrane translocase subunit TIM50⌘
M. musculusNCBI:XP_001478387 · MGI:MGI:3782048
M. musculusUniProtKB:Q7TSG2 · MGI:MGI:1926953 (Ctdp1)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1⌘
M. musculusUniProtKB:P58466 · MGI:MGI:2654470 (SCP1 · Ctdsp1)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1⌘
M. musculusUniProtKB:Q8BX07 · MGI:MGI:1098748 (SCP2 · OS4 · Ctdsp2 · D10Ertd73e)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2⌘
M. musculusUniProtKB:P58465 · MGI:MGI:1916524 (Ctdspl · SCP3 · HYA22)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like⌘
M. musculusUniProtKB:Q8BG15 · MGI:MGI:1196405 (D2Ertd485e · Ctdspl2)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2⌘
M. musculusUniProtKB:Q3TP92 · MGI:MGI:1914431 (Dullard)Dullard homolog (Xenopus laevis)⌘
M. musculusUniProtKB:Q9D880 · MGI:MGI:1913775 (Timm50 · TIM50L)translocase of inner mitochondrial membrane 50 homolog (yeast)⌘
R. norvegicusNCBI:XP_001073281 · RGD:1587684
R. norvegicusNCBI:XP_225717 · RGD:1311755 (Ctdp1)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1⌘
R. norvegicusUniProtKB:Q5XIK8 · RGD:1309219 (Ctdspl2)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2⌘
R. norvegicusUniProtKB:Q3B7T6 · RGD:1310172 (Dullard)Dullard homolog (Xenopus laevis)⌘
R. norvegicusNCBI:XP_001077330 · RGD:1304841 (Ctdspl)CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like⌘
S. cerevisiaeUniProtKB:Q03254 · SGD:S000004890 (YMR277W · FCP1)Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p)⌘
S. cerevisiaeUniProtKB:P38757 · SGD:S000001046 (YHR004C · NEM1)Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme⌘
S. cerevisiaeUniProtKB:Q07800 · SGD:S000003933 (PSR1 · YLL010C)Plasma membrane associated protein phosphatase involved in the general stress response⌘
S. cerevisiaeUniProtKB:Q07949 · SGD:S000004009 (PSR2 · YLR019W)Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in the general stress response⌘
S. cerevisiaeUniProtKB:Q02776 · SGD:S000005984 (YPL063W · TIM50)Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex)⌘
S. pombeUniProtKB:Q9P376 · GeneDB_Spombe:SPAC19B12.05c (fcp1 · SPAC19B12.05c)CTD phosphatase Fcp1⌘
S. pombeUniProtKB:O59718 · GeneDB_Spombe:SPBC3B8.10c (SPBC3B8.10c)NLI interacting factor family phiosphatase⌘
S. pombeUniProtKB:O13636 · GeneDB_Spombe:SPBC17A3.01c (SPBC17A3.01c · tim50 · SPBC8D2.21c)TIM23 translocase complex subunit Tim50⌘
S. pombeUniProtKB:Q09695 · GeneDB_Spombe:SPAC2F7.02c (SPAC2F7.02c)NLI interacting factor family phosphatase⌘
ProteinPublicationCurator Notes
UniProtKB:Q03254 · SGD:S000004890PMID:15170348 Hausmann S, et al. An encephalitozoon cuniculi ortholog of the RNA polymerase II carboxyl-terminal domain (CTD) serine phosphatase Fcp1. Biochemistry. 2004 Jun 8;43(22):7111-20.The E. cuniculi protein EcFcp1 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000060069 · UniProtKB:Q9Y5B0#604168 CONGENITAL CATARACTS, FACIAL DYSMORPHISM, AND NEUROPATHY;;CCFDN;;CATARACT, CONGENITAL, WITH FACIAL DYSMORPHISM AND NEUROPATHY
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu