P-POD: Princeton Protein Orthology Database: GO3/Nens115

This family has 81 members: 4 Arabidopsis thaliana, 8 Caenorhabditis elegans, 14 Danio rerio, 3 Dictyostelium discoideum, 19 Drosophila melanogaster, 7 Gallus gallus, 7 Homo sapiens, 7 Mus musculus, 7 Rattus norvegicus, 3 Saccharomyces cerevisiae, 2 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Nens115
81 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2027207 (F25A4.4 · F25A4_4 · AT1G75000) · NCBI:NP_177637.1⌘
A. thalianaNCBI:NP_195401.1 · TAIR:locus:2115395 (AP22.81 · AT4G36830 · AP22_81)⌘
A. thalianaNCBI:NP_187298.1 · TAIR:locus:2081116 (F24P17.3 · AT3G06470 · F24P17_3)⌘
A. thalianaNCBI:NP_187297.1 · TAIR:locus:2081126 (F24P17_4 · AT3G06460 · F24P17.4)⌘
C. elegansWB:WBGene00001241 (elo-3 · D2024.3) · UniProtKB:P49191⌘
C. elegansWB:WBGene00001242 (C40H1.4 · elo-4) · UniProtKB:Q03574⌘
C. elegansWB:WBGene00001243 (elo-5 · F41H10.7) · UniProtKB:Q20300⌘
C. elegansWB:WBGene00001244 (elo-6 · F41H10.8) · UniProtKB:Q20303⌘
C. elegansWB:WBGene00001239 (F56H11.4 · elo-1) · UniProtKB:Q20901⌘
C. elegansWB:WBGene00001245 (elo-7 · F56H11.3) · UniProtKB:Q20904⌘
C. elegansWB:WBGene00001247 (Y53F4B.2 · elo-9) · UniProtKB:Q9NAC6⌘
C. elegansWB:WBGene00001240 (F11E6.5 · elo-2) · UniProtKB:Q9XVQ9⌘
D. rerioUniProtKB:Q6PC64 · ZFIN:ZDB-GENE-030114-1 (elovl6)ELOVL family member 6, elongation of long chain fatty acids (yeast)⌘
D. rerioZFIN:ZDB-GENE-060929-240 (zgc:153394) · UniProtKB:Q08C82⌘
D. rerioUniProtKB:Q502A7 · ZFIN:ZDB-GENE-060421-5612 (elovl2)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2⌘
D. rerioZFIN:ZDB-GENE-050522-453 (zgc:112263) · UniProtKB:Q502G0⌘
D. rerioUniProtKB:Q5XJ87 · ZFIN:ZDB-GENE-041010-66 (elovl1a)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1a⌘
D. rerioUniProtKB:Q6P978 · ZFIN:ZDB-GENE-030131-7672 (elovl4)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4⌘
D. rerioZFIN:ZDB-GENE-040426-1767 (zgc:73341) · UniProtKB:Q6PBM2⌘
D. rerioUniProtKB:Q7ZTU5 · ZFIN:ZDB-GENE-030131-5485 (elovl7b)ELOVL family member 7, elongation of long chain fatty acids (yeast) b⌘
D. rerioUniProtKB:Q7ZUC3 · ZFIN:ZDB-GENE-040426-2755 (elovl1b)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b⌘
D. rerioUniProtKB:Q7ZVN0 · ZFIN:ZDB-GENE-030131-6149 (elovl7a)ELOVL family member 7, elongation of long chain fatty acids (yeast) a⌘
D. rerioENSEMBL:ENSDARG00000055946 · UniProtKB:Q802X6
D. rerioUniProtKB:Q802X6 · ENSEMBL:ENSDARG00000038639
D. rerioUniProtKB:Q8AX86 · ZFIN:ZDB-GENE-040407-2 (elovl5)ELOVL family member 5, elongation of long chain fatty acids (yeast)⌘
D. rerioZFIN:ZDB-GENE-040718-309 (zgc:92749) · UniProtKB:Q6DGW0⌘
D. discoideumUniProtKB:Q54TC9 · dictyBase:DDB_G0281821 (sre1)steroid isomerase⌘
D. discoideumUniProtKB:Q555E8 · dictyBase:DDB_G0274669 (DDB_G0274669)Similar to GNS1/SUR4 family protein.⌘
D. discoideumdictyBase:DDB_G0271066 (DDB_G0271066) · UniProtKB:Q55BY4⌘
D. melanogasterUniProtKB:Q0E5H2 · FB:FBgn0037762 (elongase · CG16905 · eloF)elongase F⌘
D. melanogasterFB:FBgn0037764 (CG9459 · CT26804) · UniProtKB:Q4V3H4⌘
D. melanogasterUniProtKB:Q5JZZ4 · FB:FBgn0052072 (CG32072 · elo68alpha · CG6261 · Elo68alpha)Elongase 68alpha⌘
D. melanogasterFB:FBgn0034382 (CG18609 · CT42569) · UniProtKB:Q6NN18⌘
D. melanogasterFB:FBgn0051141 (CG31141) · UniProtKB:Q8IMY2⌘
D. melanogasterFB:FBgn0051522 (BcDNA:LD10305 · anon-WO0118547.381 · CG9798 · BcDNA:GH22993 · CG31522) · UniProtKB:Q8IPL8⌘
D. melanogasterFB:FBgn0037534 (CG2781) · UniProtKB:Q8MS02⌘
D. melanogasterFB:FBgn0050008 (anon-WO0140519.246 · CG30008 · CG12138) · UniProtKB:Q8SXD1⌘
D. melanogasterFB:FBgn0034383 (CG17821) · UniProtKB:Q8T400⌘
D. melanogasterFB:FBgn0051523 (CG31523 · CG9798) · UniProtKB:Q95T98⌘
D. melanogasterFB:FBgn0039030 (CG6660) · UniProtKB:Q9VCT3⌘
D. melanogasterFB:FBgn0053110 (CG6926 · CG33110 · CG13844) · UniProtKB:Q9VCY5⌘
D. melanogasterFB:FBgn0038986 (CG5278) · UniProtKB:Q9VCY6⌘
D. melanogasterFB:FBgn0038985 · UniProtKB:Q9VCY7
D. melanogasterUniProtKB:Q9VCZ0 · FB:FBgn0038983 (CG5326)⌘
D. melanogasterFB:FBgn0037765 (CT26802 · CG9458) · UniProtKB:Q9VH55⌘
D. melanogasterFB:FBgn0037763 (CG16904) · UniProtKB:Q9VH57⌘
D. melanogasterFB:FBgn0037761 (CG8534) · UniProtKB:Q9VH59⌘
D. melanogasterUniProtKB:Q9VV87 · FB:FBgn0036650 (l(3)neo22 · blp · l(3)04106 · baldspot · NEST:bs18g10 · l(3)neo21 · NEST:bs18f10 · Baldspot · noa · CG3971 · l(3)01895 · l(3)02281)CG 3971⌘
G. gallusNCBI:XP_419868 · ENTREZ:421850
G. gallusNCBI:XP_001234271 · ENTREZ:770955
G. gallusNCBI:XP_429134 · ENTREZ:431579
G. gallusNCBI:XP_418947 · ENTREZ:420858
G. gallusNCBI:XP_426204 · ENTREZ:428646
G. gallusENTREZ:428772 · UniProtKB:Q5ZJR8 (RCJMB04_16d24 · IPI00594129 · ELOVL6 · ELOV6_CHICK · Q5ZJR8)Elongation of very long chain fatty acids protein 6⌘
G. gallusUniProtKB:Q5F345 (IPI00575216 · Q5F345 · RCJMB04_35f19) · ENTREZ:424564⌘
H. sapiensENSEMBL:ENSG00000066322 · UniProtKB:Q9BW60 (IPI00010187 · ELOV1_HUMAN · CGI-88 · SSC1 · ELOVL1 · Q9BW60)Elongation of very long chain fatty acids protein 1⌘
H. sapiensENSEMBL:ENSG00000197977 · UniProtKB:Q9NXB9 (IPI00413930 · ELOV2_HUMAN · SSC2 · ELOVL2 · Q9NXB9)Elongation of very long chain fatty acids protein 2⌘
H. sapiensENSEMBL:ENSG00000119915 · UniProtKB:Q9HB03 (Q9HB03 · CIG30 · ELOVL3 · IPI00054675 · ELOV3_HUMAN)Elongation of very long chain fatty acids protein 3⌘
H. sapiensENSEMBL:ENSG00000118402 · UniProtKB:Q9GZR5 (ELOVL4 · ELOV4_HUMAN · IPI00009295 · Q9GZR5)Elongation of very long chain fatty acids protein 4⌘
H. sapiensENSEMBL:ENSG00000012660 · UniProtKB:Q9NYP7 (ELOV5_HUMAN · Q9NYP7 · IPI00328307 · PRO0530 · ELOVL2 · ELOVL5)Elongation of very long chain fatty acids protein 5⌘
H. sapiensENSEMBL:ENSG00000170522 · UniProtKB:Q9H5J4 (ELOV6_HUMAN · IPI00031695 · ELOVL6 · FACE · Q9H5J4 · LCE)Elongation of very long chain fatty acids protein 6⌘
H. sapiensENSEMBL:ENSG00000164181 · UniProtKB:A1L3X0 (ELOVL7 · A1L3X0 · ELOV7_HUMAN · IPI00783761)Elongation of very long chain fatty acids protein 7⌘
M. musculusUniProtKB:Q9JLJ5 · MGI:MGI:1858959 (Ssc1 · Elovl1)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1⌘
M. musculusUniProtKB:Q9JLJ4 · MGI:MGI:1858960 (Ssc2 · Elovl2)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2⌘
M. musculusUniProtKB:O35949 · MGI:MGI:1195976 (Cig30 · Elovl3 · CIN-2)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3⌘
M. musculusUniProtKB:Q9EQC4 · MGI:MGI:1933331 (Elovl4)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4⌘
M. musculusUniProtKB:Q8BHI7 · MGI:MGI:1916051 (Elovl5 · HELO1)FEN1/Elo2, SUR4/Elo3-like · ELOVL family member 5, elongation of long chain fatty acids (yeast)⌘
M. musculusUniProtKB:Q920L5 · MGI:MGI:2156528 (Elovl6 · LCE)FEN1/Elo2, SUR4/Elo3-like · ELOVL family member 6, elongation of long chain fatty acids (yeast)⌘
M. musculusUniProtKB:Q9D2Y9 · MGI:MGI:1921809 (Elovl7)ELOVL family member 7, elongation of long chain fatty acids (yeast)⌘
R. norvegicusNCBI:XP_001062735 · RGD:1305630 (Elovl4)elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4⌘
R. norvegicusNCBI:XP_001065454 · RGD:1310560
R. norvegicusNCBI:XP_001065915 · RGD:1307263
R. norvegicusNCBI:XP_001061733 · RGD:1583400
R. norvegicusUniProtKB:Q920L7 · RGD:620583 (Elovl5)ELOVL family member 5, elongation of long chain fatty acids (yeast)⌘
R. norvegicusUniProtKB:Q920L6 · RGD:620585 (Elovl6)ELOVL family member 6, elongation of long chain fatty acids (yeast)⌘
R. norvegicusUniProtKB:Q5U2Z8 · RGD:1587151 (LOC679532)similar to Elongation of very long chain fatty acids protein 1⌘
S. cerevisiaeUniProtKB:P39540 · SGD:S000003732 (ELO1 · YJL196C)Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids⌘
S. cerevisiaeUniProtKB:P25358 · SGD:S000000630 (VBM2 · GNS1 · FEN1 · YCR034W · ELO2)Fatty acid elongase, involved in sphingolipid biosynthesis⌘
S. cerevisiaeUniProtKB:P40319 · SGD:S000004364 (SUR4 · VBM1 · APA1 · ELO3 · YLR372W · SRE1)Elongase, involved in fatty acid and sphingolipid biosynthesis⌘
S. pombeUniProtKB:Q9UTF7 · GeneDB_Spombe:SPAC1B2.03c (SPAC1B2.03c)GNS1/SUR4 family protein⌘
S. pombeUniProtKB:Q7LKX0 · GeneDB_Spombe:SPAC1639.01c (SPAC806.09c · SPAC1639.01c)GNS1/SUR4 family protein⌘
ProteinPublicationCurator Notes
UniProtKB:P39540 · SGD:S000003732PMID:15975553 Chertemps T, et al. A new elongase selectively expressed in Drosophila male reproductive system. Biochem Biophys Res Commun. 2005 Aug 12;333(4):1066-72.The D. melanogaster protein CG32072-PA complements a homologous mutation in S. cerevisiae. Drosophila elo68alpha complements a yeast elo1 fas2 double mutant.
UniProtKB:P25358 · SGD:S000000630PMID:15333757 Mietkiewska E, et al. Seed-specific heterologous expression of a nasturtium FAE gene in Arabidopsis results in a dramatic increase in the proportion of erucic acid. Plant Physiol. 2004 Sep;136(1):2665-75.The T. majus protein FAE does not complement a homologous mutation in S. cerevisiae.
UniProtKB:P40319 · SGD:S000004364PMID:15333757 Mietkiewska E, et al. Seed-specific heterologous expression of a nasturtium FAE gene in Arabidopsis results in a dramatic increase in the proportion of erucic acid. Plant Physiol. 2004 Sep;136(1):2665-75.The T. majus protein FAE does not complement a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000118402 · UniProtKB:Q9GZR5#600110 STARGARDT DISEASE 3; STGD3;;MACULAR DYSTROPHY WITH FLECKS, TYPE 3;;STARGARDT-LIKE MACULAR DYSTROPHY, AUTOSOMAL DOMINANT
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