P-POD: Princeton Protein Orthology Database: GO3/Jaccard98

This family has 140 members: 17 Arabidopsis thaliana, 9 Caenorhabditis elegans, 22 Danio rerio, 9 Dictyostelium discoideum, 8 Drosophila melanogaster, 2 Escherichia coli, 15 Gallus gallus, 18 Homo sapiens, 18 Mus musculus, 15 Rattus norvegicus, 4 Saccharomyces cerevisiae, 3 Schizosaccharomyces pombe.

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GO3/Jaccard98
140 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_187617.1 · TAIR:locus:2100063 (T22K18.11 · AT3G10060)⌘
A. thalianaNCBI:NP_201240.1 · TAIR:locus:2173438 (immunophilin · MSJ1.19 · ATFKBP12 · AT5G64350 · MSJ1_19 · FKBP12)FK506-BINDING PROTEIN⌘
A. thalianaNCBI:NP_566993.1 · TAIR:locus:2084435 (F5K20.310 · DEI1 · AT3G54010 · PAS1)PASTICCINO 1⌘
A. thalianaNCBI:NP_187840.4 · TAIR:locus:2092467 (AT3G12340 · T2E22.33)⌘
A. thalianaNCBI:NP_199380.1 · TAIR:locus:2171958 (MRA19.7 · AT5G45680 · MRA19_7)⌘
A. thalianaNCBI:NP_196161.1 · TAIR:locus:2153519 (K18I23.23 · AT5G05420 · K18I23_23)⌘
A. thalianaNCBI:NP_567717.1 · TAIR:locus:2138029 (AT4G25340 · T30C3_20 · T30C3.20)⌘
A. thalianaNCBI:NP_181884.1 · TAIR:locus:2058218 (T1O24.30 · AT2G43560)⌘
A. thalianaNCBI:NP_199668.1 · TAIR:locus:2152561 (K15N18.12 · K15N18_12 · AT5G48570)⌘
A. thalianaNCBI:NP_566762.1 · TAIR:locus:2090235 (MJL12.19 · FKBP15-1 · AT3G25220)⌘
A. thalianaNCBI:NP_199669.1 · TAIR:locus:2152506 (IMMUNOPHILIN · K15N18.5 · AT5G48580 · K15N18_5 · FKBP15-2)⌘
A. thalianaNCBI:NP_567098.2 · TAIR:locus:2103366 (T8B10.30 · AT3G60370)⌘
A. thalianaNCBI:NP_191111.1 · TAIR:locus:2100016 (T22E16.180 · AT3G55520)⌘
A. thalianaNCBI:NP_001118695.1 · TAIR:locus:2090265 (MJL12.21 · ROF1 · AT3G25230)ROTAMASE FKBP 1⌘
A. thalianaNCBI:NP_188801.2 · TAIR:locus:2089890 (UCU2 · ATFKBP42 · MIL23.21 · TWD1 · AT3G21640 · FKBP42)ULTRACURVATA 2 · TWISTED DWARF 1⌘
A. thalianaNCBI:NP_193718.1 · TAIR:locus:2134035 (AT4G19830 · T16H5_190 · T16H5.190)⌘
A. thalianaNCBI:NP_568067.1 · TAIR:locus:2135287 (T19P19.100 · AT4G39710 · T19P19_100)⌘
C. elegansWB:WBGene00001428 (fkb-3 · C05C8.3) · UniProtKB:O16309⌘
C. elegansWB:WBGene00001431 (fkb-6 · F31D4.3) · UniProtKB:O45418⌘
C. elegansWB:WBGene00001432 (B0511.1 · fkb-7) · UniProtKB:O61826⌘
C. elegansWB:WBGene00016966 (C56C10.10) · UniProtKB:Q18888⌘
C. elegansWB:WBGene00001426 (F36H1.1 · fkb-1) · UniProtKB:Q20107⌘
C. elegansWB:WBGene00001429 (fkb-4 · ZC455.10) · UniProtKB:Q23338⌘
C. elegansWB:WBGene00001433 (Y18D10A.25 · fkb-8) · UniProtKB:Q8I4E5⌘
C. elegansWB:WBGene00001430 (C50F2.6 · fkb-5) · UniProtKB:Q95Q60⌘
C. elegansWB:WBGene00001427 (Y18D10A.19 · fkb-2) · UniProtKB:Q9U2Q8⌘
D. rerioENSEMBL:ENSDARP00000015318
D. rerioENSEMBL:ENSDARP00000077876
D. rerioENSEMBL:ENSDARP00000002900
D. rerioENSEMBL:ENSDARG00000054947 · UniProtKB:A2CF47
D. rerioENSEMBL:ENSDARG00000062796 · UniProtKB:A3KQS9
D. rerioZFIN:ZDB-GENE-050302-4 (si:dkey-189h5.5) · UniProtKB:A3QK11⌘
D. rerioUniProtKB:Q503C0 · ZFIN:ZDB-GENE-030616-419 (fkbp3)FK506 binding protein 3⌘
D. rerioZFIN:ZDB-GENE-040927-9 (zgc:103752) · UniProtKB:Q642J1⌘
D. rerioUniProtKB:Q6DBV9 · ZFIN:ZDB-GENE-040801-210 (fkbp14)FK506 binding protein 14⌘
D. rerioUniProtKB:Q6DBZ1 · ZFIN:ZDB-GENE-040801-23 (fkbp9)FK506 binding protein 9⌘
D. rerioUniProtKB:Q6IQ94 · ZFIN:ZDB-GENE-030131-514 (fkbp4)FK506 binding protein 4⌘
D. rerioENSEMBL:ENSDARG00000001734 · UniProtKB:Q6P3J6
D. rerioUniProtKB:Q6P3J6 · ENSEMBL:ENSDARG00000056490
D. rerioUniProtKB:Q6PBJ1 · ZFIN:ZDB-GENE-040426-1785 (fkbp1b)FK506 binding protein 1b⌘
D. rerioZFIN:ZDB-GENE-030131-7275 (zgc:73373) · UniProtKB:Q6PBJ8⌘
D. rerioUniProtKB:Q7ZVA7 · ZFIN:ZDB-GENE-030131-3101 (fkbp10)FK506 binding protein 10⌘
D. rerioUniProtKB:Q7ZZ60 · ZFIN:ZDB-GENE-030616-182 (fkbp7)FK506 binding protein 7⌘
D. rerioUniProtKB:Q7ZZA3 · ZFIN:ZDB-GENE-030616-357 (fkbp11)FK506 binding protein 11⌘
D. rerioUniProtKB:Q801U5 · ZFIN:ZDB-GENE-030616-630 (fkbp5)FK506 binding protein 5⌘
D. rerioUniProtKB:Q90ZC5 · ZFIN:ZDB-GENE-030131-6735 (aip)aryl hydrocarbon receptor interacting protein⌘
D. rerioZFIN:ZDB-GENE-040912-126 (zgc:101826) · UniProtKB:A9JSW0⌘
D. rerioZFIN:ZDB-GENE-050208-116 (si:ch211-13k12.1) · UniProtKB:Q5CZU8⌘
D. discoideumNCBI:EDR41087.1 · dictyBase:DDB_G0295681
D. discoideumUniProtKB:Q554J3 · dictyBase:DDB_G0275227 (DDB_G0275227)FKBP-type peptidylprolyl cis-trans isomerase (PPIase)⌘
D. discoideumUniProtKB:Q54SR7 · dictyBase:DDB_G0282267 (DDB_G0282267)FKBP-type peptidylprolyl cis-trans isomerase (PPIase)⌘
D. discoideumUniProtKB:Q54N80 · dictyBase:DDB_G0285455 (impA)FKBP-type peptidylprolyl cis-trans isomerase (PPIase)⌘
D. discoideumUniProtKB:Q54NB6 · dictyBase:DDB_G0285357 (DDB_G0285357)FKBP-type peptidylprolyl cis-trans isomerase (PPIase)⌘
D. discoideumUniProtKB:Q54G21 · dictyBase:DDB_G0290433 (DDB_G0290433)FKBP-type peptidylprolyl cis-trans isomerase domain-containing protein, pectin lyase-like family protein⌘
D. discoideumdictyBase:DDB_G0278455 (DDB_G0278455) · UniProtKB:Q54Y27⌘
D. discoideumUniProtKB:Q54LG6 · dictyBase:DDB_G0286549 (flpA)FKBP-like protein, FKBP-type peptidylprolyl cis-trans isomerase (PPIase)⌘
D. discoideumdictyBase:DDB_G0283815 (DDB_G0283815) · UniProtKB:Q54QI6⌘
D. melanogasterUniProtKB:P48375 · FB:FBgn0013954 (Fk506-bp2 · CG11001 · dFKBP12 · FKBP12 · DrFKBP12 · FKBP · 143729_at · FK506-bp2)FK506-binding protein 2 · FK506-binding protein⌘
D. melanogasterUniProtKB:P54397 · FB:FBgn0013269 (FKbp39 · FK506-bp1 · FKBP39 · FK506bp1 · CG6226)FK506-binding protein 1⌘
D. melanogasterUniProtKB:Q9VL78 · FB:FBgn0029174 (anon-WO0118547.161 · FKBP59 · FKBP59-bp1 · CG4535 · l(2)k00424 · dFKBP59 · l(2)k09010)FK506-binding protein FKBP59⌘
D. melanogasterFB:FBgn0034368 (CG5482) · UniProtKB:Q7K3D4⌘
D. melanogasterFB:FBgn0030345 (CG1847) · UniProtKB:Q8IR85⌘
D. melanogasterFB:FBgn0037930 (BcDNA:RH50927 · BcDNA:GM09283 · CG14715) · UniProtKB:Q9VGK3⌘
D. melanogasterUniProtKB:Q9W1I9 · FB:FBgn0003401 (shutdown · Shutdown · CG4735 · shu)shut down⌘
D. melanogasterFB:FBgn0010470 (CG9847 · l(2)00734 · FKB13 · Fkbp13 · BcDNA.GM07659 · BcDNA:GM07659 · FKBP13 · GM07659 · BcDNA:GH08925) · UniProtKB:Q9XZ54⌘
E. coliUniProtKB:P45523 · ECOLI:G7716-MONOMER (yzzS · b3347 · ECK3334 · fkpA · FkpA)peptidyl-prolyl cis-trans isomerase; in protein folding⌘
E. coliUniProtKB:P0A9L3 · ECOLI:G7865-MONOMER (ECK4203 · fklB · FklB · b4207 · ytfC)FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)⌘
G. gallusNCBI:XP_424615 · ENTREZ:427013
G. gallusNCBI:XP_001233085 · ENTREZ:769785
G. gallusNCBI:XP_418157 · ENTREZ:420035
G. gallusNCBI:XP_418735 · ENTREZ:420636
G. gallusNCBI:XP_415708 · ENTREZ:417460
G. gallusNCBI:XP_418241 · ENTREZ:420123
G. gallusNCBI:XP_415541 · ENTREZ:417267
G. gallusNCBI:XP_421981 · ENTREZ:424129
G. gallusUniProtKB:Q5ZJT4 (Q5ZJT4 · RCJMB04_15n8 · IPI00589127) · ENTREZ:418261⌘
G. gallusUniProtKB:Q646T7 (IPI00588770 · Q646T7 · FKBP51) · ENTREZ:421186⌘
G. gallusUniProtKB:Q7T048 (IPI00582243 · Q7T048) · ENTREZ:395123⌘
G. gallusENTREZ:395254 · UniProtKB:Q8QGU2 (FKBP12.6 · Q8QGU2 · IPI00601848)Peptidyl-prolyl cis-trans isomerase⌘
G. gallusENTREZ:374233 · UniProtKB:Q90ZG0 (IPI00583918 · Q90ZG0 · FKBP12)Peptidyl-prolyl cis-trans isomerase⌘
G. gallusENTREZ:395353 · UniProtKB:Q90ZK7 (IPI00588963 · Q90ZK7 · FKBP25)Peptidyl-prolyl cis-trans isomerase⌘
G. gallusUniProtKB:Q9YIC3 (IPI00600123 · cFKBP/SMAP · Q9YIC3) · ENTREZ:395652⌘
H. sapiensENSEMBL:ENSG00000129221 · UniProtKB:Q9NZN9 (AIPL1_HUMAN · IPI00303131 · Q9NZN9 · AIPL1)Aryl-hydrocarbon-interacting protein-like 1⌘
H. sapiensENSEMBL:ENSG00000110711 · UniProtKB:O00170 (O00170 · XAP2 · AIP · IPI00010460 · AIP_HUMAN)AH receptor-interacting protein⌘
H. sapiensENSEMBL:ENSG00000141756 · UniProtKB:Q96AY3 (FKBP65 · FKB10_HUMAN · IPI00303300 · FKBP10 · Q96AY3 · PSEC0056)FK506-binding protein 10⌘
H. sapiensENSEMBL:ENSG00000134285 · UniProtKB:Q9NYL4 (Q9NYL4 · FKBP19 · FKBP11 · UNQ336/PRO535 · FKB11_HUMAN · IPI00009885)FK506-binding protein 11⌘
H. sapiensENSEMBL:ENSG00000106080 · UniProtKB:Q9NWM8 (FKB14_HUMAN · IPI00017331 · UNQ322/PRO381 · FKBP14 · Q9NWM8 · FKBP22)FK506-binding protein 14⌘
H. sapiensENSEMBL:ENSG00000119321 · UniProtKB:Q5T1M5 (IPI00853400 · IPI00646791 · KIAA0674 · Q5T1M5 · FKB15_HUMAN · IPI00855962 · FKBP15)FK506-binding protein 15⌘
H. sapiensENSEMBL:ENSG00000088832 · UniProtKB:P62942 (FKBP1A · FKB1A_HUMAN · FKBP1 · FKBP12 · IPI00873810 · P62942)Peptidyl-prolyl cis-trans isomerase FKBP1A⌘
H. sapiensENSEMBL:ENSG00000119782 · UniProtKB:P68106 (FKBP12.6 · IPI00073704 · FKB1B_HUMAN · FKBP9 · FKBP1B · IPI00396151 · OTK4 · FKBP1L · P68106)Peptidyl-prolyl cis-trans isomerase FKBP1B⌘
H. sapiensENSEMBL:ENSG00000173486 · UniProtKB:P26885 (FKBP13 · FKBP2_HUMAN · FKBP2 · P26885 · IPI00002535)FK506-binding protein 2⌘
H. sapiensENSEMBL:ENSG00000100442 · UniProtKB:Q00688 (FKBP3_HUMAN · IPI00024157 · FKBP25 · Q00688 · FKBP3)FK506-binding protein 3⌘
H. sapiensENSEMBL:ENSG00000004478 · UniProtKB:Q02790 (FKBP4 · FKBP4_HUMAN · IPI00219005 · Q02790)FK506-binding protein 4⌘
H. sapiensENSEMBL:ENSG00000096060 · UniProtKB:Q13451 (FKBP5 · Q13451 · FKBP5_HUMAN · AIG6 · FKBP51 · IPI00218775)FK506-binding protein 5⌘
H. sapiensENSEMBL:ENSG00000077800 · UniProtKB:O75344 (FKBP6_HUMAN · FKBP36 · O75344 · FKBP6 · IPI00025280)FK506-binding protein 6⌘
H. sapiensENSEMBL:ENSG00000079150 · UniProtKB:Q9Y680 (FKBP7_HUMAN · IPI00218686 · FKBP23 · IPI00001914 · FKBP7 · UNQ670/PRO1304 · Q9Y680)FK506-binding protein 7⌘
H. sapiensENSEMBL:ENSG00000105701 · UniProtKB:Q14318 (IPI00328161 · FKBP38 · FKBP8 · FKBP8_HUMAN · IPI00640341 · Q14318)FK506-binding protein 8⌘
H. sapiensENSEMBL:ENSG00000122642 · UniProtKB:O95302 (O95302 · IPI00182126 · FKBP60 · FKBP63 · FKBP9 · FKBP9_HUMAN)FK506-binding protein 9⌘
H. sapiensENSEMBL:ENSG00000204315 · UniProtKB:Q9UIM3 (IPI00032110 · NG7 · FKBPL · Q9UIM3 · FKBPL_HUMAN · DIR1)FK506-binding protein-like⌘
H. sapiensENSEMBL:ENSG00000177906 · UniProtKB:Q9UIM3 (IPI00032110 · NG7 · FKBPL · Q9UIM3 · FKBPL_HUMAN · DIR1)FK506-binding protein-like⌘
M. musculusNCBI:XP_001479958 · MGI:MGI:3641946
M. musculusUniProtKB:Q924K1 · MGI:MGI:2148800 (Aipl1)aryl hydrocarbon receptor-interacting protein-like 1⌘
M. musculusUniProtKB:O08915 · MGI:MGI:109622 (D19Bwg1412e · Fkbp16 · Ara9 · Xap2 · Aip)aryl-hydrocarbon receptor-interacting protein⌘
M. musculusUniProtKB:Q61576 · MGI:MGI:104769 (FKBP65 · Fkbp6 · Fkbp1-rs · Fkbp-rs1 · 65kDa · Fkbp10)FK506 binding protein 10⌘
M. musculusUniProtKB:Q9D1M7 · MGI:MGI:1913370 (Fkbp11)FK506 binding protein 11⌘
M. musculusUniProtKB:P59024 · MGI:MGI:2387639 (Fkbp14 · FKBP22)FK506 binding protein 14⌘
M. musculusUniProtKB:Q6P9Q6 · MGI:MGI:2444782 (Fkbp15 · FKBP133)FK506 binding protein 15⌘
M. musculusUniProtKB:P26883 · MGI:MGI:95541 (mFKBP12 · mFKBP1 · 12kDa · Fkbp1 · Fkbp · FKBP12 · Fkbp1a)FK506 binding protein 1a⌘
M. musculusUniProtKB:Q9Z2I2 · MGI:MGI:1336205 (FKBP12.6 · 12.6kDa · Fkbp1b)FK506 binding protein 1b⌘
M. musculusUniProtKB:P45878 · MGI:MGI:95542 (mFKBP2 · 13kDa · Fkbp2 · mFKBP13)FK506 binding protein 2⌘
M. musculusUniProtKB:Q62446 · MGI:MGI:1353460 (FKBP25 · 25kDa · Fkbp3)FK506 binding protein 3⌘
M. musculusUniProtKB:P30416 · MGI:MGI:95543 (FKBP-52 · 59kDa · p59 · Fkbp4 · FKPB52)FK506 binding protein 4⌘
M. musculusUniProtKB:Q64378 · MGI:MGI:104670 (51kDa · Dit1 · D17Ertd592e · FKBP51 · Fkbp5)FK506 binding protein 5⌘
M. musculusUniProtKB:Q91XW8 · MGI:MGI:2137612 (D5Ertd724e · Fkbp6 · 36kDa)FK506 binding protein 6⌘
M. musculusUniProtKB:O54998 · MGI:MGI:1336879 (Fkbp7 · FKBP23)FK506 binding protein 7⌘
M. musculusUniProtKB:O35465 · MGI:MGI:1341070 (Fkbp38 · 38kDa · Fkbp8)FK506 binding protein 8⌘
M. musculusUniProtKB:Q9Z247 · MGI:MGI:1350921 (Fkbp9 · FKBP60 · FKBP63)FK506 binding protein 9⌘
M. musculusUniProtKB:O35450 · MGI:MGI:1932127 (Fkbpl · NG7 · Ppiase-X · DIR1)FK506 binding protein-like⌘
R. norvegicusNCBI:XP_216717 · RGD:1304992 (Fkbp3)FK506 binding protein 3⌘
R. norvegicusNCBI:XP_001065788 · RGD:1305293 (Fkbp7)FK506 binding protein 7⌘
R. norvegicusNCBI:XP_222082 · RGD:1308926 (Fkbp6)FK506 binding protein 6, 36kDa⌘
R. norvegicusNCBI:XP_342847 · RGD:1304816 (Fkbp15)FK506 binding protein 15⌘
R. norvegicusNCBI:XP_001072401 · RGD:1560660 (Fkbp2)FK506 binding protein 2⌘
R. norvegicusUniProtKB:Q9JLG9 · RGD:70906 (Aipl1)aryl hydrocarbon receptor-interacting protein-like 1⌘
R. norvegicusUniProtKB:Q5FWY5 · RGD:628619 (Aip)aryl-hydrocarbon receptor-interacting protein⌘
R. norvegicusUniProtKB:Q62658 · RGD:2617 (Fkbp1a)FK506 binding protein 1a⌘
R. norvegicusUniProtKB:P97534 · RGD:61835 (Fkbp1b)FK506 binding protein 1b⌘
R. norvegicusUniProtKB:Q3B7U9 · RGD:1308670 (Fkbp8)FK506 binding protein 8, 38kDa⌘
R. norvegicusUniProtKB:Q66H94 · RGD:1549757 (Fkbp9)FK506 binding protein 9, 63 kDa⌘
R. norvegicusUniProtKB:Q6MG81 · RGD:1303227 (Fkbpl)FK506 binding protein-like⌘
R. norvegicusUniProtKB:Q5U2T9 · RGD:1309155 (Fkbp5)FK506 binding protein 5⌘
R. norvegicusUniProtKB:Q5U2V1 · RGD:1549751 (Fkbp10)FK506 binding protein 10⌘
R. norvegicusUniProtKB:Q5XID8 · RGD:1311705 (Fkbp14)FK506 binding protein 14⌘
S. cerevisiaeUniProtKB:P32472 · SGD:S000002927 (FKB2 · YDR519W · FPR2)Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin⌘
S. cerevisiaeUniProtKB:P38911 · SGD:S000004539 (FPR3 · NPI46 · YML074C)Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase)⌘
S. cerevisiaeUniProtKB:Q06205 · SGD:S000004441 (YLR449W · FPR4)Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus⌘
S. cerevisiaeUniProtKB:P20081 · SGD:S000005079 (RBP1 · YNL135C · FPR1 · FKB1)Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin⌘
S. pombeUniProtKB:O74191 · GeneDB_Spombe:SPBC1347.02 (fkbp39 · SPBC1347.02)FKBP-type peptidyl-prolyl cis-trans isomerase⌘
S. pombeUniProtKB:Q10175 · GeneDB_Spombe:SPAC27F1.06c (SPAC27F1.06c)FKBP-type peptidyl-prolyl cis-trans isomerase⌘
S. pombeUniProtKB:O42993 · GeneDB_Spombe:SPBC839.17c (fkh1 · SPBC839.17c)FKBP-type peptidyl-prolyl cis-trans isomerase Fkh1⌘
ProteinPublicationCurator Notes
UniProtKB:P20081 · SGD:S000005079PMID:1996117 Koltin Y, et al. Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein. Mol Cell Biol. 1991 Mar;11(3):1718-23.The S. cerevisiae protein FPR1 was expressed in E. coli, but complementation was not directly tested.
UniProtKB:P38911 · SGD:S000004539PMID:7525596 Benton BM, et al. A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. J Cell Biol. 1994 Nov;127(3):623-39.The S. cerevisiae protein FPR3 was expressed in E. coli, but complementation was not directly tested.
UniProtKB:P38911 · SGD:S000004539PMID:7925954 Manning-Krieg UC, et al. Purification of FKBP-70, a novel immunophilin from Saccharomyces cerevisiae, and cloning of its structural gene, FPR3. FEBS Lett. 1994 Sep 19;352(1):98-103.The S. cerevisiae protein FPR3 was expressed in E. coli, but complementation was not directly tested.
UniProtKB:P32472 · SGD:S000002927PMID:14657499 Willingham S, et al. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science. 2003 Dec 5;302(5651):1769-72.The H. sapiens protein P26885 complements a homologous mutation in S. cerevisiae. The human ortholog FKBP2 (P26885) was overexpressed in the yeast fpr2 null mutant.
UniProtKB:P20081 · SGD:S000005079PMID:1996117 Koltin Y, et al. Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein. Mol Cell Biol. 1991 Mar;11(3):1718-23.The H. sapiens protein P62942 complements a homologous mutation in S. cerevisiae. Based on references referred to in this paper, the authors appear to be referring to FKBP1A (P62942).
UniProtKB:P20081 · SGD:S000005079PMID:7507662 Bossard MJ, et al. Catalytic and ligand binding properties of the FK506 binding protein FKBP12: effects of the single amino acid substitution of Tyr82 to Leu. Biochem J. 1994 Jan 15;297 ( Pt 2):365-72.The H. sapiens protein P62942 complements a homologous mutation in S. cerevisiae. Based on references referred to in this paper, the authors appear to be referring to FKBP1A (P62942).
UniProtKB:P20081 · SGD:S000005079PMID:8413204 Cafferkey R, et al. Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity. Mol Cell Biol. 1993 Oct;13(10):6012-23.The H. sapiens protein P62942 complements a homologous mutation in S. cerevisiae. Based on references referred to in this paper, the authors appear to be referring to FKBP1A (P62942).
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (5)
ENSEMBL:ENSG00000129221 · UniProtKB:Q9NZN9+604392 ARYLHYDROCARBON-INTERACTING RECEPTOR PROTEIN-LIKE 1; AIPL1RETINITIS PIGMENTOSA, JUVENILE, AUTOSOMAL DOMINANT, INCLUDED;;CONE-ROD DYSTROPHY, AUTOSOMAL DOMINANT, INCLUDED
ENSEMBL:ENSG00000110711 · UniProtKB:O00170#604393 LEBER CONGENITAL AMAUROSIS 4; LCA4
ENSEMBL:ENSG00000077800 · UniProtKB:O75344#219090 PITUITARY ADENOMA, ACTH-SECRETING;;CUSHING DISEASE, PITUITARY
#102200 PITUITARY ADENOMA, GROWTH HORMONE-SECRETING;;SOMATOTROPINOMA, FAMILIAL ISOLATED; FIS;;ISOLATED FAMILIAL SOMATOTROPINOMA; IFS;;SOMATOTROPHINOMA, FAMILIAL;;ACROMEGALY DUE TO PITUITARY ADENOMAPITUITARY ADENOMA PREDISPOSITION, INCLUDED; PAP, INCLUDED;;PITUITARY ADENOMA, FAMILIAL ISOLATED, INCLUDED; FIPA, INCLUDED;;SOMATOSTATIN ANALOG, RESISTANCE TO, INCLUDED
ENSEMBL:ENSG00000077800 · UniProtKB:O75344#194050 WILLIAMS-BEUREN SYNDROME; WBS;;CHROMOSOME 7q11.23 DELETION SYNDROME;;WILLIAMS SYNDROME; WMS; WSHYPERCALCEMIA, INFANTILE, INCLUDED;;SUPRAVALVAR AORTIC STENOSIS, INCLUDED;;ELFIN FACIES WITH HYPERCALCEMIA
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