P-POD: Princeton Protein Orthology Database: GO3/Jaccard85

This family has 158 members: 23 Arabidopsis thaliana, 10 Caenorhabditis elegans, 12 Danio rerio, 10 Dictyostelium discoideum, 14 Drosophila melanogaster, 2 Escherichia coli, 17 Gallus gallus, 19 Homo sapiens, 18 Mus musculus, 17 Rattus norvegicus, 7 Saccharomyces cerevisiae, 9 Schizosaccharomyces pombe.

• Protein Family
• Functional Conservation (1)
• Download Files (5)
• Disease References (1)

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

158 members.

Organism	Protein (Synonyms)	Description	AmiGO
A. thaliana	NCBI:NP_172152.1 · TAIR:locus:2009200 (F12K11.4 · F12K11_4 · NIH · AT1G06670)	DEIH-BOX RNA/DNA HELICASE · NUCLEAR DEIH-BOXHELICASE
A. thaliana	NCBI:NP_196994.1 · TAIR:locus:2147785 (AT5G14900 · F2G14_20 · F2G14.20)
A. thaliana	NCBI:NP_174527.2 · TAIR:locus:2033723 (ESP3 · AT1G32490 · F5D14.27 · EMB2733 · F5D14_27)	ENHANCED SILENCING PHENOTYPE 3 · EMBRYO DEFECTIVE 2733
A. thaliana	NCBI:NP_850154.2 · TAIR:locus:2052841 (T11J7.19 · ATVT-1 · HVT1 · AT2G30800)	HELICASE IN VASCULAR TISSUE AND TAPETUM
A. thaliana	NCBI:NP_567206.1 · TAIR:locus:2125211 (F3I3_40 · F3I3.40 · AT4G01020)
A. thaliana	NCBI:NP_196805.1 · TAIR:locus:2182340 (T24H18.180 · AT5G13010 · EMB3011 · T24H18_180)	embryo defective 3011
A. thaliana	NCBI:NP_680142.2 · TAIR:locus:504954904 (AT5G04895)
A. thaliana	NCBI:NP_191790.1 · TAIR:locus:2095989 (T12C14.10 · AT3G62310)
A. thaliana	NCBI:NP_176102.1 · TAIR:locus:2196255 (T15M6_6 · T15M6.6 · AT1G58050)
A. thaliana	NCBI:NP_182247.1 · TAIR:locus:2065210 (T8I13.9 · AT2G47250)
A. thaliana	NCBI:NP_173961.3 · TAIR:locus:2197965 (T1K7.25 · T1K7_25 · AT1G26370)
A. thaliana	NCBI:NP_193401.1 · TAIR:locus:2129036 (DL4365C · FCAALL.3 · AT4G16680)
A. thaliana	NCBI:NP_175298.2 · TAIR:locus:2008144 (F11I4_16 · AT1G48650 · F11I4.16)
A. thaliana	NCBI:NP_176103.2 · TAIR:locus:2196265 (T15M6_7 · T15M6.7 · AT1G58060)
A. thaliana	NCBI:NP_178223.2 · TAIR:locus:2038796 (AT2G01130 · F10A8.28)
A. thaliana	NCBI:NP_174605.1 · TAIR:locus:2007003 (F10C21.6 · AT1G33390)
A. thaliana	NCBI:NP_182290.1 · TAIR:locus:2043413 (AT2G47680 · F17A22.7)
A. thaliana	NCBI:NP_189288.1 · TAIR:locus:2088847 (AT3G26560 · MFE16.8)
A. thaliana	NCBI:NP_181077.3 · TAIR:locus:2062492 (T32F12.28 · MEE29 · AT2G35340 · T32F12_28)	maternal effect embryo arrest 29
A. thaliana	NCBI:NP_850255.1 · TAIR:locus:2039280 (F11F19_17 · F11F19.17 · AT2G35920)
A. thaliana	NCBI:NP_567558.1 · TAIR:locus:505006494 (AT4G18465)
A. thaliana	NCBI:NP_564296.1 · TAIR:locus:2010549 (F13K9_28 · AT1G27900 · F13K9.28)
A. thaliana	NCBI:NP_196599.2 · TAIR:locus:2142459 (F12B17.280 · F12B17_280 · AT5G10370)
C. elegans	WB:WBGene00018967 (F56D2.6) · UniProtKB:Q20875
C. elegans	WB:WBGene00003392 (C04H5.6 · mog-4) · UniProtKB:O45244 (DHX16_CAEEL · C04H5.6 · mog-4)	Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4
C. elegans	WB:WBGene00022056 (Y67D2.6) · UniProtKB:Q9BKQ8
C. elegans	WB:WBGene00004355 (rha-1 · T07D4.3) · UniProtKB:Q22307
C. elegans	WB:WBGene00003389 (K03H1.2 · mog-1) · UniProtKB:P34498 (K03H1.2 · MOG1_CAEEL · mog-1)	Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1
C. elegans	WB:WBGene00003393 (EEED8.5 · mog-5) · UniProtKB:Q09530 (EEED8.5 · mog-5 · MOG5_CAEEL)	Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5
C. elegans	WB:WBGene00015525 (rha-2 · C06E1.10) · UniProtKB:P34305
C. elegans	WB:WBGene00020263 (T05E8.3) · UniProtKB:O01598
C. elegans	WB:WBGene00009922 (F52B5.3) · UniProtKB:Q20644
C. elegans	WB:WBGene00021365 (Y37E11AM.1 · smgl-2) · UniProtKB:Q9N437
D. rerio	ENSEMBL:ENSDARP00000060939
D. rerio	ENSEMBL:ENSDARP00000071318
D. rerio	ENSEMBL:ENSDARP00000074799
D. rerio	ENSEMBL:ENSDARP00000070535
D. rerio	ENSEMBL:ENSDARP00000075688
D. rerio	ENSEMBL:ENSDARP00000008078
D. rerio	ENSEMBL:ENSDARG00000059455 · UniProtKB:A1A5W6
D. rerio	ENSEMBL:ENSDARG00000061168 · UniProtKB:A2BIE5
D. rerio	UniProtKB:A2RV37 · ZFIN:ZDB-GENE-030131-4505 (dhx37)	DEAH (Asp-Glu-Ala-His) box polypeptide 37
D. rerio	ENSEMBL:ENSDARG00000061922 · UniProtKB:A3KQN8
D. rerio	ENSEMBL:ENSDARG00000063419 · UniProtKB:Q1ECW4
D. rerio	UniProtKB:Q7ZVV8 · ZFIN:ZDB-GENE-030131-8589 (dhx16)	DEAH (Asp-Glu-Ala-His) box polypeptide 16
D. discoideum	NCBI:EAL73211.1 · dictyBase:DDB_G0267516 (dhx57)	DEAD/DEAH box helicase, RWD domain-containing protein
D. discoideum	UniProtKB:Q54NJ4 · dictyBase:DDB_G0285213 (prp43 · dhx15)	DEAD/DEAH box helicase, putative RNA splicing factor
D. discoideum	UniProtKB:Q54MH3 · dictyBase:DDB_G0285937 (dhx16)	DEAD/DEAH box helicase, putative RNA splicing factor
D. discoideum	UniProtKB:Q54F05 · dictyBase:DDB_G0291183 (dhx8 · prp22)	DEAD/DEAH box helicase, putative RNA splicing factor
D. discoideum	UniProtKB:Q54KG8 · dictyBase:DDB_G0287351 (dhx37)	DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54MH4 · dictyBase:DDB_G0285843 (dhx38 · helD · prp16)	DEAD/DEAH box helicase, putative RNA splicing factor
D. discoideum	UniProtKB:Q55CD3 · dictyBase:DDB_G0270110 (dhx33)	DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q55EC3 · dictyBase:DDB_G0269306 (dhx35)	DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q55F84 · dictyBase:DDB_G0268212 (DDB_G0268212)	putative DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q869Z1 · dictyBase:DDB_G0275313 (dhx9)	ATP-dependent RNA helicase, DEAD/DEAH box helicase
D. melanogaster	UniProtKB:Q9W1I2 · FB:FBgn0004581 (gonial-cell-neoplasm · CG10331 · Bgcn · PNBP · fs(2)eo6 · bcgn · peppercorn · benign-(2)-gonial-cell-neoplasm · ben(2)gcn · pep · fs(2)eoQS2 · fs(2)eo-C · bgcn · CG30170 · b(2)cgn · cg10331 · gcn · CG10330 · BGCN · b(2)gcn)	benign gonial cell neoplasm · Putative nuclear binding protein · benign gonial cell neoplasia
D. melanogaster	FB:FBgn0001330 (l(1)2Eb · N1 · CG3228 · EG:30B8.2 · l67 · N8 · kz · l(1)N4 · kurz) · UniProtKB:O46072
D. melanogaster	UniProtKB:P24785 · FB:FBgn0002774 (male-lethal · nap[ts] · mls · male-killer · Maleless · MLE · CG11680 · maleless · mak · mle · nap · mll)	maleless-no-action potential · no action potential
D. melanogaster	FB:FBgn0086895 (CG8241 · pea · Prp22 · peanuts · cg8241) · UniProtKB:A1Z9L3
D. melanogaster	UniProtKB:Q26453 · FB:FBgn0003483 (spn-E/hls · spindle-E · homeless/spindle-E · HOMELESS · Spindle-E · homeless · Homeless · spnE · Spn-E · fs(1)hls · fs(3)hls · spn-E · hls · CG3158)	female sterile(3)homeless · Spindle E · spindle E · Spindle-E (homeless) · spn E
D. melanogaster	UniProtKB:Q7K3M5 · FB:FBgn0033160 (cg11107 · CG11107 · anon-EST:Liang-1.18)	clone 1.18
D. melanogaster	FB:FBgn0032883 (cg9323 · CG9323 · 38E.15) · UniProtKB:Q8SWT2
D. melanogaster	UniProtKB:Q9VIZ3 · FB:FBgn0086444 (l(2)E104 · cg10689 · Cb · l(2)37Cb · CG10689)	lethal (2) 37Cb
D. melanogaster	FB:FBgn0032194 (CG4901 · cg4901) · UniProtKB:Q9VL25
D. melanogaster	FB:FBgn0031631 (cg3225 · CG3225) · UniProtKB:Q9VR29
D. melanogaster	FB:FBgn0052533 (CG32533 · CG14198 · CG12211 · cg12211) · UniProtKB:Q9VWI5
D. melanogaster	FB:FBgn0030833 (cg8915 · helicasa · CG8915) · UniProtKB:Q9VX63
D. melanogaster	UniProtKB:Q9VY54 · FB:FBgn0026713 (CG1375 · l(1)G0476 · l(1)G0416 · l(1)G0103 · l(1)G0007 · l(1)G0176 · l(1)G0491 · EP784 · CG32604 · l(1)G0308 · cg1405 · l(1)G0028 · CG1405 · EP764)	lethal (1) G0007
D. melanogaster	FB:FBgn0030246 (cg1582 · CG1582) · UniProtKB:Q9VZ55
E. coli	UniProtKB:P43329 · ECOLI:G6732-MONOMER (b1413 · ECK1406 · hrpA · HrpA)	ATP-dependent helicase
E. coli	UniProtKB:P37024 · ECOLI:EG12329-MONOMER (HrpB · yadO · hrpB · b0148 · ECK0147)	predicted ATP-dependent helicase
G. gallus	NCBI:XP_001235278 · ENTREZ:772090
G. gallus	NCBI:XP_415104 · ENTREZ:416813
G. gallus	NCBI:XP_421393 · ENTREZ:423488
G. gallus	NCBI:XP_422834 · ENTREZ:425032
G. gallus	NCBI:XP_424198 · ENTREZ:426560
G. gallus	NCBI:XP_424728 · ENTREZ:427136
G. gallus	NCBI:XP_001233396 · ENTREZ:417499
G. gallus	NCBI:XP_418105 · ENTREZ:419982
G. gallus	NCBI:XP_417352 · ENTREZ:419172
G. gallus	NCBI:XP_427757 · ENTREZ:430203
G. gallus	NCBI:XP_426893 · ENTREZ:429336
G. gallus	NCBI:XP_428556 · ENTREZ:431006
G. gallus	NCBI:XP_001235891 · ENTREZ:776366
G. gallus	NCBI:XP_413970 · ENTREZ:415602
G. gallus	ENTREZ:420376 · UniProtKB:Q5ZI74 (DHX30 · Q5ZI74 · DHX30_CHICK · IPI00593383 · RCJMB04_29l1)	Putative ATP-dependent RNA helicase DHX30
G. gallus	UniProtKB:Q5F3A9 (RCJMB04_24b10 · IPI00577528 · Q5F3A9) · ENTREZ:422813
G. gallus	UniProtKB:Q5ZLE8 (IPI00591998 · RCJMB04_6i5 · Q5ZLE8) · ENTREZ:415875
H. sapiens	ENSEMBL:ENSG00000109606 · UniProtKB:O43143 (DBP1 · IPI00396435 · DHX15_HUMAN · DDX15 · DHX15 · O43143)	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15
H. sapiens	ENSEMBL:ENSG00000204560 · UniProtKB:O60231 (DDX16 · DBP2 · O60231 · DHX16_HUMAN · DHX16 · KIAA0577 · IPI00552073)	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
H. sapiens	ENSEMBL:ENSG00000206397 · UniProtKB:O60231 (DDX16 · DBP2 · O60231 · DHX16_HUMAN · DHX16 · KIAA0577 · IPI00552073)	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
H. sapiens	ENSEMBL:ENSG00000067248 · UniProtKB:Q7Z478 (DHX29 · IPI00217413 · DDX29 · DHX29_HUMAN · Q7Z478)	ATP-dependent RNA helicase DHX29
H. sapiens	ENSEMBL:ENSG00000132153 · UniProtKB:Q7L2E3 (IPI00411733 · KIAA0890 · DHX30 · IPI00164906 · DDX30 · DHX30_HUMAN · Q7L2E3)	Putative ATP-dependent RNA helicase DHX30
H. sapiens	ENSEMBL:ENSG00000089876 · UniProtKB:Q7L7V1 (Q7L7V1 · DHX32_HUMAN · IPI00334601 · IPI00644447 · DDX32 · DHX32)	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32
H. sapiens	ENSEMBL:ENSG00000005100 · UniProtKB:Q9H6R0 (DHX33_HUMAN · IPI00655950 · DHX33 · Q9H6R0 · IPI00302860 · DDX33)	Putative ATP-dependent RNA helicase DHX33
H. sapiens	ENSEMBL:ENSG00000134815 · UniProtKB:Q14147 (DHX34_HUMAN · Q14147 · IPI00382739 · KIAA0134 · DDX34 · DHX34)	Probable ATP-dependent RNA helicase DHX34
H. sapiens	ENSEMBL:ENSG00000101452 · UniProtKB:Q9H5Z1 (DDX35 · Q9H5Z1 · IPI00030288 · C20orf15 · DHX35 · DHX35_HUMAN)	Probable ATP-dependent RNA helicase DHX35
H. sapiens	ENSEMBL:ENSG00000174953 · UniProtKB:Q9H2U1 (Q9H2U1 · DHX36_HUMAN · MLEL1 · IPI00784170 · IPI00217760 · IPI00027415 · DDX36 · DHX36 · KIAA1488 · RHAU)	Probable ATP-dependent RNA helicase DHX36
H. sapiens	ENSEMBL:ENSG00000150990 · UniProtKB:Q8IY37 (KIAA1517 · DDX37 · IPI00217630 · DHX37 · DHX37_HUMAN · Q8IY37)	Probable ATP-dependent RNA helicase DHX37
H. sapiens	ENSEMBL:ENSG00000108406 · UniProtKB:Q8IX18 (IPI00410110 · ARG147 · DHX40 · Q8IX18 · IPI00797226 · IPI00789290 · DDX40 · DHX40_HUMAN)	Probable ATP-dependent RNA helicase DHX40
H. sapiens	ENSEMBL:ENSG00000163214 · UniProtKB:Q6P158 (IPI00749029 · Q6P158 · IPI00399364 · DHX57_HUMAN · DHX57 · IPI00168885)	Putative ATP-dependent RNA helicase DHX57
H. sapiens	ENSEMBL:ENSG00000067596 · UniProtKB:Q14562 (IPI00031508 · Q14562 · DDX8 · DHX8_HUMAN · DHX8)	ATP-dependent RNA helicase DHX8
H. sapiens	ENSEMBL:ENSG00000135829 · UniProtKB:Q08211 (IPI00844578 · Q08211 · DHX9_HUMAN · LKP · DDX9 · NDH2 · DHX9)	ATP-dependent RNA helicase A
H. sapiens	ENSEMBL:ENSG00000144045 · UniProtKB:Q8TE96 (Q8TE96 · DQX1_HUMAN · IPI00843897 · IPI00844595 · IPI00385794 · DQX1)	ATP-dependent RNA helicase DQX1
H. sapiens	ENSEMBL:ENSG00000140829 · UniProtKB:Q92620 (Q92620 · DDX38 · IPI00294211 · KIAA0224 · PRP16 · DHX38 · PRP16_HUMAN)	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
H. sapiens	ENSEMBL:ENSG00000156414 · UniProtKB:Q8NDG6 (IPI00384419 · TDRD9 · Q8NDG6 · TDR9_HUMAN · IPI00413613)	Putative ATP-dependent RNA helicase TDRD9
H. sapiens	ENSEMBL:ENSG00000047188 · UniProtKB:Q9H6S0 (IPI00010200 · YTHDC2 · Q9H6S0 · YTDC2_HUMAN)	YTH domain-containing protein 2
M. musculus	NCBI:NP_081263 · MGI:MGI:1916442 (Ddx16 · Dhx16 · DBP2)	DEAH (Asp-Glu-Ala-His) box polypeptide 16
M. musculus	NCBI:NP_976064 · MGI:MGI:3028576 (Dhx37 · LOC381671 · LOC208144)	DEAH (Asp-Glu-Ala-His) box polypeptide 37
M. musculus	NCBI:NP_665685 · MGI:MGI:1918965 (Ddx35 · Dhx35)	DEAH (Asp-Glu-Ala-His) box polypeptide 35
M. musculus	NCBI:NP_848467 · MGI:MGI:1927617 (Prp16 · Ddx38 · Dhx38)	DEAH (Asp-Glu-Ala-His) box polypeptide 38
M. musculus	UniProtKB:O35286 · MGI:MGI:1099786 (DBP1 · Ddx15 · mDEAH9 · Dhx15 · HRH2)	DEAH (Asp-Glu-Ala-His) box polypeptide 15
M. musculus	UniProtKB:Q6PGC1 · MGI:MGI:2145374 (Dhx29)	DEAH (Asp-Glu-Ala-His) box polypeptide 29
M. musculus	UniProtKB:Q99PU8 · MGI:MGI:1920081 (Dhx30 · Ddx30)	DEAH (Asp-Glu-Ala-His) box polypeptide 30
M. musculus	UniProtKB:Q8BZS9 · MGI:MGI:2141813 (Ddx32 · Dhx32)	DEAH (Asp-Glu-Ala-His) box polypeptide 32
M. musculus	UniProtKB:Q80VY9 · MGI:MGI:2445102 (Ddx33 · Dhx33)	DEAH (Asp-Glu-Ala-His) box polypeptide 33
M. musculus	UniProtKB:Q9DBV3 · MGI:MGI:1918973 (Dhx34 · Ddx34)	DEAH (Asp-Glu-Ala-His) box polypeptide 34
M. musculus	UniProtKB:Q8VHK9 · MGI:MGI:1919412 (Dhx36 · Ddx36)	DEAH (Asp-Glu-Ala-His) box polypeptide 36
M. musculus	UniProtKB:Q6PE54 · MGI:MGI:1914737 (ARG147 · Dhx40 · DDX40)	DEAH (Asp-Glu-Ala-His) box polypeptide 40
M. musculus	UniProtKB:Q6P5D3 · MGI:MGI:2147067 (Dhx57)	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
M. musculus	UniProtKB:A2A4P0 · MGI:MGI:1306823 (Dhx8 · Ddx8 · mDEAH6)	RNA helicase · DEAH (Asp-Glu-Ala-His) box polypeptide 8
M. musculus	UniProtKB:O70133 · MGI:MGI:108177 (RHA · leukophysin · NDHII · Ddx9 · Dhx9)	NDH II · RNA helicase · nuclear DNA helicase II · DEAH (Asp-Glu-Ala-His) box polypeptide 9
M. musculus	UniProtKB:Q924H9 · MGI:MGI:2136388 (Dqx1)	DEAQ RNA-dependent ATPase
M. musculus	UniProtKB:Q14BI7 · MGI:MGI:1921941 (Tdrd9)	tudor domain containing 9
M. musculus	UniProtKB:B2RR83 · MGI:MGI:2448561 (Ythdc2)	YTH domain containing 2
R. norvegicus	NCBI:XP_227203 · RGD:1308767 (Dhx36)	DEAH (Asp-Glu-Ala-His) box polypeptide 36
R. norvegicus	NCBI:XP_341949 · RGD:1311740
R. norvegicus	NCBI:XP_001062397 · RGD:1584452 (LOC684903)	similar to Probable ATP-dependent RNA helicase DHX34 (DEAH box protein 34)
R. norvegicus	NCBI:XP_342566 · RGD:1311165
R. norvegicus	NCBI:XP_213772 · RGD:1306837 (Dhx37)	DEAH (Asp-Glu-Ala-His) box polypeptide 37
R. norvegicus	NCBI:XP_001057161 · RGD:1591766
R. norvegicus	NCBI:XP_001066523 · RGD:1308548 (Dhx9)	DEAH (Asp-Glu-Ala-His) box polypeptide 9
R. norvegicus	NCBI:XP_215481 · RGD:1308724
R. norvegicus	NCBI:XP_214053 · RGD:1308072 (Dhx15)	DEAH (Asp-Glu-Ala-His) box polypeptide 15
R. norvegicus	NCBI:XP_238048 · RGD:1310345 (Dhx38)	DEAH (Asp-Glu-Ala-His) box polypeptide 38
R. norvegicus	UniProtKB:Q5BJS0 · RGD:1308888 (Dhx30)	DEAH (Asp-Glu-Ala-His) box polypeptide 30
R. norvegicus	UniProtKB:Q5XI69 · RGD:1359618 (Dhx40)	DEAH (Asp-Glu-Ala-His) box polypeptide 40
R. norvegicus	RGD:1306942 (Tdrd9) · UniProtKB:Q3MHU3 (Q3MHU3 · Tdrd9 · IPI00655293 · IPI00895578 · TDR9_RAT)	tudor domain containing 9 · Putative ATP-dependent RNA helicase TDRD9
R. norvegicus	UniProtKB:Q4G031 · RGD:1310340 (Dhx57)	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
R. norvegicus	UniProtKB:Q6MG13 · RGD:1302963 (Dhx16)	DEAH (Asp-Glu-Ala-His) box polypeptide 16
R. norvegicus	UniProtKB:Q6TXG4 · RGD:1310723 (Dhx8)	DEAH (Asp-Glu-Ala-His) box polypeptide 8
R. norvegicus	NCBI:XP_213370 · RGD:1307239
S. cerevisiae	UniProtKB:Q04217 · SGD:S000004735 (ECM16 · DHR1 · YMR128W)	Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis
S. cerevisiae	UniProtKB:P36009 · SGD:S000001561 (DHR2 · YKL078W)	Predominantly nucleolar DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis
S. cerevisiae	UniProtKB:P15938 · SGD:S000001794 (PRP16 · YKR086W)	RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-dependent RNA unwinding activity
S. cerevisiae	UniProtKB:P24384 · SGD:S000000815 (PRP22 · YER013W)	DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing
S. cerevisiae	UniProtKB:P20095 · SGD:S000005294 (YNR011C · PRP2 · RNA2)	RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing
S. cerevisiae	UniProtKB:P53131 · SGD:S000003088 (YGL120C · JA1 · PRP43)	RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome
S. cerevisiae	UniProtKB:Q06698 · SGD:S000004411 (YLR419W)	Putative helicase with limited sequence similarity to human Rb protein
S. pombe	UniProtKB:Q10752 · GeneDB_Spombe:SPBC19C2.01 (SPBC19C2.01 · cdc28 · prp8)	ATP-dependent RNA helicase Cdc28
S. pombe	UniProtKB:O42945 · GeneDB_Spombe:SPBC16H5.10c (SPBC16H5.10c · prp43)	ATP-dependent RNA helicase Prp43
S. pombe	UniProtKB:Q03319 · GeneDB_Spombe:SPAC2G11.11c (SPAC2G11.11c · prh1)	ATP-dependent RNA helicase Prh1
S. pombe	UniProtKB:Q9P774 · GeneDB_Spombe:SPBC1711.17 (SPBC17G9.01 · SPBC1711.17 · prp16)	ATP-dependent RNA helicase Prp16
S. pombe	UniProtKB:O42643 · GeneDB_Spombe:SPAC10F6.02c (prp22 · SPAC10F6.02c)	ATP-dependent RNA helicase Prp22
S. pombe	UniProtKB:O94536 · GeneDB_Spombe:SPCC895.09c (SPCC895.09c · ucp12)	ATP-dependent RNA helicase Ucp1 · ATP-dependent RNA helicase Ucp1 (predicted)
S. pombe	UniProtKB:O60114 · GeneDB_Spombe:SPBC15C4.05 (SPBC15C4.05)	ATP-dependent RNA/DNA helicase · ATP-dependent RNA/DNA helicase (predicted)
S. pombe	UniProtKB:Q9HDY4 · GeneDB_Spombe:SPAPB1A10.06c (SPAPB1A10.06c)	ATP-dependent RNA helicase Dhr1
S. pombe	UniProtKB:Q9HE06 · GeneDB_Spombe:SPAC20H4.09 (SPAC20H4.09)	ATP-dependent RNA helicase, spliceosomal

Protein	Publication	Curator Notes
UniProtKB:P24384 · SGD:S000000815	7935475 Ono Y, et al. Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22. Mol Cell Biol. 1994 Nov;14(11):7611-20.	The H. sapiens protein Q14562 complements a homologous mutation in S. cerevisiae. This paper shows partial complementation of a yeast prp22 temperature-sensitive mutant by expression of human HRH1/DHX8 (Q14562). The results strongly suggest that HRH1 is a functional human homolog of the yeast Prp22 protein.

Description	Suffix
Sequences in this family	.fasta
mafft aligned Fasta file	.afasta
phyml newick file	.newick
Notung rooted & rearranged newick file	.newick.rooting.0.rearrange.0
Notung Homolog Table	.newick.rooting.0.rearrange.0.homologs.csv

SGD Disease Papers (1)
UniProtKB:Q06698 · SGD:S000004411	16181730 Takemura M (2005) Evolutionary history of the retinoblastoma gene from archaea to eukarya. Biosystems 82(3):266-72