P-POD: Princeton Protein Orthology Database: GO3/Jaccard819

This family has 30 members: 1 Dictyostelium discoideum, 5 Escherichia coli, 15 Saccharomyces cerevisiae, 9 Schizosaccharomyces pombe.

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GO3/Jaccard819
30 members.
OrganismProtein (Synonyms)DescriptionAmiGO
D. discoideumUniProtKB:Q86M88 · dictyBase:DDB_G0283345 (comD)major facilitator superfamily protein, drug resistance transporter, EmrB/QacA subfamily protein⌘
E. coliUniProtKB:P0AEJ0 · ECOLI:EMRB-MONOMER (EmrB · b2686 · ECK2680 · emrB)EmrB multidrug MFS transporter⌘
E. coliUniProtKB:P52600 · ECOLI:EMRY-MONOMER (b2367 · emrY · ECK2363 · EmrY)EmrY putative multidrug MFS transporter⌘
E. coliUniProtKB:P31474 · ECOLI:YIEO-MONOMER (hsrA · HsrA · yieO · b3754 · ECK3748)HsrA drug MFS transporter⌘
E. coliUniProtKB:P36554 · ECOLI:B2077-MONOMER (YegB · yegB · b2077 · ECK2073 · mdtD)⌘
E. coliUniProtKB:P76269 · ECOLI:B1828-MONOMER (ECK1827 · yebQ · b1828 · YebQ)predicted transporter⌘
S. cerevisiaeUniProtKB:P38731 · SGD:S000001032 (YHL040C · ARN1)Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates⌘
S. cerevisiaeUniProtKB:P38724 · SGD:S000001039 (YHL047C · ARN2 · TAF1)Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates⌘
S. cerevisiaeUniProtKB:P13090 · SGD:S000004584 (YML116W · ATR1 · SNQ1)Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide⌘
S. cerevisiaeUniProtKB:P50080 · SGD:S000003456 (AZR1 · YGR224W)Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole⌘
S. cerevisiaeUniProtKB:Q08299 · SGD:S000005518 (ENB1 · YOL158C · ARN4)Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation⌘
S. cerevisiaeUniProtKB:P33335 · SGD:S000006402 (NOR1 · SGE1 · YPR198W)Plasma membrane multidrug transporter of the major facilitator superfamily, acts as an extrusion permease⌘
S. cerevisiaeUniProtKB:P39980 · SGD:S000000791 (YEL065W · ARN3 · SIT1)Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates⌘
S. cerevisiaeUniProtKB:Q04301 · SGD:S000004694 (VBA1 · YMR088C)Permease of basic amino acids in the vacuolar membrane⌘
S. cerevisiaeUniProtKB:P38358 · SGD:S000000497 (VBA2 · YBR293W)Permease of basic amino acids in the vacuolar membrane⌘
S. cerevisiaeUniProtKB:P25594 · SGD:S000000574 (YCL069W · VBA3)Permease of basic amino acids in the vacuolar membrane⌘
S. cerevisiaeUniProtKB:P25596 · SGD:S000000575 (YCL073C)Protein of unconfirmed function⌘
S. cerevisiaeUniProtKB:P36172 · SGD:S000001813 (VBA5 · YKR105C)Putative transporter of the Major Facilitator Superfamily (MFS)⌘
S. cerevisiaeUniProtKB:P36173 · SGD:S000001814 (YKR106W)Protein of unconfirmed function⌘
S. cerevisiaeUniProtKB:Q03263 · SGD:S000004892 (YMR279C)Putative protein of unknown function⌘
S. cerevisiaeUniProtKB:Q08902 · SGD:S000005905 (YOR378W)Putative protein of unknown function⌘
S. pombeUniProtKB:Q09752 · GeneDB_Spombe:SPBC12C2.13c (SPBC21D10.04c · SPBC12C2.13c · fnx1)vacuolar membrane amino acid uptake transporter Fnx1⌘
S. pombeUniProtKB:O74395 · GeneDB_Spombe:SPBC4F6.09 (SPBC4F6.09 · str1)siderophore-iron transporter Str1⌘
S. pombeUniProtKB:O94607 · GeneDB_Spombe:SPCC61.01c (SPCC622.20c · SPCC61.01c · str2)siderophore-iron transporter Str2⌘
S. pombeUniProtKB:Q92341 · GeneDB_Spombe:SPAC1F8.03c (SPAC1F8.03c · str3)siderophore-iron transporter Str3⌘
S. pombeUniProtKB:Q10072 · GeneDB_Spombe:SPAC3H1.06c (SPAC3H1.06c)membrane transporter⌘
S. pombeUniProtKB:O42922 · GeneDB_Spombe:SPBC16A3.17c (SPBC16A3.17c)membrane transporter⌘
S. pombeUniProtKB:Q9HE13 · GeneDB_Spombe:SPAC1399.02 (SPAC1399.02)membrane transporter⌘
S. pombeUniProtKB:O59726 · GeneDB_Spombe:SPBC3E7.06c (fnx2 · SPBC3E7.06c)vacuolar membrane amino acid uptake transporter Fnx2⌘
S. pombeUniProtKB:Q9P6J7 · GeneDB_Spombe:SPBC1683.03c (SPBC1683.03c)membrane transporter⌘
ProteinPublicationCurator Notes
UniProtKB:P38731 · SGD:S000001032PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit1 complements a homologous mutation in S. cerevisiae. F. graminearum Sit1 functions as a siderophore-iron transporter in yeast and complements an arn1 arn2 arn3 arn4 quadruple mutant; this experiment was performed in an fet3 background to prevent the uptake of free iron, which would interfere with the analysis.
UniProtKB:P38731 · SGD:S000001032PMID:12888492 Pelletier B, et al. Fep1 represses expression of the fission yeast Schizosaccharomyces pombe siderophore-iron transport system. Nucleic Acids Res. 2003 Aug 1;31(15):4332-44.The S. pombe protein str1+ complements a homologous mutation in S. cerevisiae. Expression of str1+ in an fet3 arn1-4 background restored ferrichrome-dependent iron uptake.
UniProtKB:P38724 · SGD:S000001039PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit1 complements a homologous mutation in S. cerevisiae. F. graminearum Sit1 functions as a siderophore-iron transporter in yeast and complements an arn1 arn2 arn3 arn4 quadruple mutant; this experiment was performed in an fet3 background to prevent the uptake of free iron, which would interfere with the analysis.
UniProtKB:P39980 · SGD:S000000791PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit1 complements a homologous mutation in S. cerevisiae. F. graminearum Sit1 functions as a siderophore-iron transporter in yeast and complements an arn1 arn2 arn3 arn4 quadruple mutant; this experiment was performed in an fet3 background to prevent the uptake of free iron, which would interfere with the analysis.
UniProtKB:Q08299 · SGD:S000005518PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit1 complements a homologous mutation in S. cerevisiae. F. graminearum Sit1 functions as a siderophore-iron transporter in yeast and complements an arn1 arn2 arn3 arn4 quadruple mutant; this experiment was performed in an fet3 background to prevent the uptake of free iron, which would interfere with the analysis.
UniProtKB:P38724 · SGD:S000001039PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit2 does not complement a homologous mutation in S. cerevisiae. F. graminearum Sit2 did not function as a siderophore-iron transporter in yeast.
UniProtKB:P39980 · SGD:S000000791PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit2 does not complement a homologous mutation in S. cerevisiae. F. graminearum Sit2 did not function as a siderophore-iron transporter in yeast.
UniProtKB:Q08299 · SGD:S000005518PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit2 does not complement a homologous mutation in S. cerevisiae. F. graminearum Sit2 did not function as a siderophore-iron transporter in yeast.
UniProtKB:P38731 · SGD:S000001032PMID:16750173 Park YS, et al. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1634-42.The F. graminearum protein FgSit2 does not complement a homologous mutation in S. cerevisiae. F. graminearum Sit2 did not function as a siderophore-iron transporter in yeast.
UniProtKB:P13090 · SGD:S000004584PMID:14595517 Takacova M, et al. KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease. Curr Genet. 2004 Feb;45(1):1-8.The K. lactis protein KNQ1 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
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