P-POD: Princeton Protein Orthology Database: GO3/Jaccard80

This family has 168 members: 18 Arabidopsis thaliana, 12 Caenorhabditis elegans, 21 Danio rerio, 11 Dictyostelium discoideum, 15 Drosophila melanogaster, 3 Escherichia coli, 11 Gallus gallus, 17 Homo sapiens, 13 Mus musculus, 25 Rattus norvegicus, 14 Saccharomyces cerevisiae, 8 Schizosaccharomyces pombe.

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GO3/Jaccard80
168 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_198206.1 · TAIR:locus:2182783 (BIP1 · T26D3_10 · T26D3.10 · AT5G28540)⌘
A. thalianaNCBI:NP_850984.1 · TAIR:locus:2017859
A. thalianaNCBI:NP_173055.1 · TAIR:locus:2200462 (T24D18.14 · Hsp70b · AT1G16030 · T24D18_14)heat shock protein 70B⌘
A. thalianaNCBI:NP_180771.1 · TAIR:locus:2045457 (HSP70T-2 · AT2G32120 · F22D22.13 · F22D22_13)HEAT-SHOCK PROTEIN 70T-2⌘
A. thalianaNCBI:NP_195870.1 · TAIR:locus:2181833 (HSC70-1 · T22P11_90 · AT-HSC70-1 · HSP70-1 · HSC70 · AT5G02500 · T22P11.90)HEAT SHOCK COGNATE PROTEIN 70 · HEAT SHOCK PROTEIN 70-1 · HEAT SHOCK COGNATE PROTEIN 70-1 · ARABIDOPSIS THALIANA HEAT SHOCK COGNATE PROTEIN 70-1⌘
A. thalianaNCBI:NP_187864.1 · TAIR:locus:2101222 (T2E22.11 · HSP70 · AT3G12580)heat shock protein 70⌘
A. thalianaNCBI:NP_178111.1 · TAIR:locus:2016364 (AT1G79930 · F19K16.11 · F19K16_11 · HSP91)⌘
A. thalianaNCBI:NP_172382.1 · TAIR:locus:2035994 (F7G19.5 · F7G19_5 · BIP3 · AT1G09080)⌘
A. thalianaNCBI:NP_196521.1 · TAIR:locus:2144801 (F17I14.220 · HSC70-5 · AT5G09590 · F17I14_220 · MTHSC70-2)MITOCHONDRIAL HSP70 2 · HEAT SHOCK COGNATE · HEAT SHOCK PROTEIN 70⌘
A. thalianaNCBI:NP_194159.1 · TAIR:locus:2135897 (AT4G24280 · T22A6.110 · T22A6_110 · cpHsc70-1)chloroplast heat shock protein 70-1⌘
A. thalianaNCBI:NP_851119.1 · TAIR:locus:2165715 (BIP · AT5G42020 · MJC20_12 · MJC20.12 · BIP2)luminal binding protein⌘
A. thalianaNCBI:NP_195504.2 · TAIR:locus:2121022 (mtHsc70-1 · F20D10.30 · AT4G37910 · F20D10_30)mitochondrial heat shock protein 70-1⌘
A. thalianaNCBI:NP_567510.1 · TAIR:locus:2129021
A. thalianaNCBI:NP_195869.1 · TAIR:locus:2181818 (T22P11_80 · T22P11.80 · AT5G02490)⌘
A. thalianaNCBI:NP_172631.1 · TAIR:locus:2027337 (F25C20_19 · AT1G11660 · F25C20.19)⌘
A. thalianaNCBI:NP_199802.1 · TAIR:locus:2158834 (HSC70-7 · AT5G49910 · K9P8.5 · K9P8_5)CPHSC70-2EAT SHOCK PROTEIN 70-2 · HEAT SHOCK PROTEIN 70-7 · HEAT SHOCK PROTEIN 70 · CHLOROPLAST HEAT SHOCK PROTEIN 70-2⌘
A. thalianaNCBI:NP_187555.1 · TAIR:locus:2074984 (F3L24.33 · AT3G09440)⌘
A. thalianaNCBI:NP_176036.1 · TAIR:locus:2010713 (F13N6_9 · ERD2 · AT1G56410 · F13N6.9 · HSP70T-1)EARLY-RESPONSIVE TO DEHYDRATION 2 · HEAT SHOCK PROTEIN 70T-1⌘
C. elegansWB:WBGene00002005 (hsp-1 · F26D10.3) · UniProtKB:P09446 (hsp-1 · F26D10.3 · HSP7A_CAEEL · hsp70a)Heat shock 70 kDa protein A⌘⌘
C. elegansWB:WBGene00002007 (hsp-3 · C15H9.6) · UniProtKB:P27420⌘
C. elegansWB:WBGene00002008 (F43E2.8 · hsp-4) · UniProtKB:P20163⌘
C. elegansWB:WBGene00002010 (C37H5.8 · hsp-6) · UniProtKB:P11141⌘
C. elegansWB:WBGene00016250 (C30C11.4) · UniProtKB:Q05036⌘
C. elegansWB:WBGene00002026 (hsp-70 · C12C8.1) · UniProtKB:O45246⌘
C. elegansWB:WBGene00006059 (stc-1 · F54C9.2) · UniProtKB:Q20752⌘
C. elegansWB:WBGene00011771 (T14G8.3b) · UniProtKB:Q22515⌘
C. elegansWB:WBGene00020781 (T24H7.2) · UniProtKB:Q22758⌘
C. elegansWB:WBGene00008714 (F11F1.1) · UniProtKB:Q9TW52⌘
C. elegansWB:WBGene00009691 (F44E5.4) · UniProtKB:Q9XTL8⌘
C. elegansWB:WBGene00009692 (F44E5.5) · UniProtKB:Q9XTL8⌘
D. rerioENSEMBL:ENSDARP00000060062
D. rerioENSEMBL:ENSDARP00000070052
D. rerioENSEMBL:ENSDARP00000004394
D. rerioUniProtKB:Q90473 · ZFIN:ZDB-GENE-990415-92 (hspa8)heat shock protein 8⌘
D. rerioENSEMBL:ENSDARG00000068897 · UniProtKB:A4QN42
D. rerioUniProtKB:A4QNX8 · ZFIN:ZDB-GENE-070410-58 (hspa13)heat shock protein 13⌘
D. rerioZFIN:ZDB-GENE-031217-2 · UniProtKB:O42359
D. rerioENSEMBL:ENSDARG00000029688 · UniProtKB:O42360
D. rerioENSEMBL:ENSDARG00000055721 · UniProtKB:O42360
D. rerioENSEMBL:ENSDARG00000068869 · UniProtKB:Q1MT77
D. rerioENSEMBL:ENSDARG00000068859 · UniProtKB:Q1MT79
D. rerioZFIN:ZDB-GENE-041210-377 (si:dkey-61p9.8) · UniProtKB:Q5RJ15⌘
D. rerioZFIN:ZDB-GENE-040426-1221 (zgc:63663) · UniProtKB:Q6PGX4⌘
D. rerioENSEMBL:ENSDARG00000021924 · UniProtKB:Q6PH56
D. rerioUniProtKB:Q7ZUW2 · ZFIN:ZDB-GENE-030131-5344 (hyou1)hypoxia up-regulated 1⌘
D. rerioUniProtKB:Q7ZYY3 · ZFIN:ZDB-GENE-030828-12 (hspa9)heat shock protein 9⌘
D. rerioENSEMBL:ENSDARG00000055723 · UniProtKB:Q9IAC1
D. rerioUniProtKB:Q5RGE6 · ZFIN:ZDB-GENE-041210-73 (hspa14)heat shock protein 14⌘
D. rerioUniProtKB:Q7SZD3 · ZFIN:ZDB-GENE-031001-11 (hspa5)heat shock protein 5⌘
D. rerioUniProtKB:Q7ZU46 · ZFIN:ZDB-GENE-040426-2832 (hspa4l)heat shock protein 4, like⌘
D. rerioUniProtKB:Q7ZUM5 · ZFIN:ZDB-GENE-030131-6018 (hspa4)heat shock protein 4⌘
D. discoideumUniProtKB:Q8T869 · dictyBase:DDB_G0276445 (DDB_G0276445)heat shock protein Hsp70 family protein⌘
D. discoideumUniProtKB:P36415 · dictyBase:DDB_G0269144 (hspB · rcdEE · hsc70-1 · hsp70 · hsc70)heat shock protein, heat shock cognate protein Hsc70-1⌘
D. discoideumUniProtKB:Q557E0 · dictyBase:DDB_G0273623 (hspE-2 · hsp70 · hsc70 · hspE · hsc70-2)heat shock protein, heat shock cognate protein Hsc70-2⌘
D. discoideumUniProtKB:Q557E0 · dictyBase:DDB_G0273249 (hsp70 · hsc70 · hspE · hsc70-2 · hspE-1)heat shock protein, heat shock cognate protein Hsc70-2⌘
D. discoideumUniProtKB:Q54BE0 · dictyBase:DDB_G0293674 (DDB_G0293674)Hsc70 protein.⌘
D. discoideumUniProtKB:Q54BD8 · dictyBase:DDB_G0293678 (DDB_G0293678)P36415 Heat shock cognate protein (Aginactin).⌘
D. discoideumUniProtKB:Q54MR6 · dictyBase:DDB_G0285709 (hspN · DDB_G0285709)heat shock protein Hsp70 family protein⌘
D. discoideumUniProtKB:Q8I0H7 · dictyBase:DDB_G0293298 (mhsp70)mitochondrial Hsp70 precursor⌘
D. discoideumUniProtKB:Q6TMK3 · dictyBase:DDB_G0290187 (hspH)heat shock protein Hsp70 family protein⌘
D. discoideumUniProtKB:Q54BE1 · dictyBase:DDB_G0293672 (DDB_G0293672)BiP (Fragment).⌘
D. discoideumUniProtKB:Q54TS8 · dictyBase:DDB_G0281581 (DDB_G0281581)78 kDa glucose-regulated protein homolog.⌘
D. melanogasterUniProtKB:O97125 · FB:FBgn0001230 (Hsp-68 · HSP68 · CG5436 · Hsp68 · 68 · hsp68)Heat shock protein 68⌘
D. melanogasterUniProtKB:P82910 · FB:FBgn0013275 (hsp-70 · Hsp70A · Hsp70Aa · hsp70 · HSP70 · hs70 · Hsp70 · hsp70(87A) · dhsp70 · hsp70Aa · hsp70A · Heat-shock-protein-70Aa · dHsp70 · CG31366 · 87A · hsp70a)Protein 70 · hsp 70 · heat-shock protein 70 · 87A locus · hsp70 87A · heat shock 70 · Hsp 70⌘
D. melanogasterUniProtKB:P02825 · FB:FBgn0013276 (hsp-70 · Hsp70A · HSP70 · hs70 · hsp70(87A) · dhsp70 · hsp70A · CG18743 · GRP78 · hsp70 · Heat-shock-protein-70Ab · Hsp70 · dHsp70 · Hsp70Ab · hsp70Ab · DMHSP7A2 · hsp70a)Protein 70 · hsp 70 · heat-shock protein 70 · 87A locus · hsp70 87A · heat shock 70 · Hsp 70⌘
D. melanogasterUniProtKB:Q8INI8 · FB:FBgn0013277 (hsp-70 · CG31449 · Heat-shock-protein-70Ba · Hsp70Ba · hsp70 · HSP70 · Hsp70 · dhsp70 · hsp70B · Hsp70B · dHsp70 · hsp70Ba · Hsp70(87C))Protein 70 · hsp70 87C · heat-shock protein 70 · 87C locus · heat shock 70 · Hsp 70⌘
D. melanogasterUniProtKB:Q9BIS2 · FB:FBgn0013278 (hsp-70 · hsp70Bb · DMHSP7D1 · Hsp70Bbc · HSP70 · dhsp70 · hsp70B · Hsp70Bb · CG31359 · Hsp70(87C) · Hsp70A7d · Hsp70Bc · hsp70 · Hsp70 · Hsp70B · dHsp70 · Heat-shock-protein-70Bb)Protein 70 · hsp70 87C · heat-shock protein 70 · 87C locus · Hsp 70⌘
D. melanogasterUniProtKB:Q9VG58 · FB:FBgn0051354 (CG5834 · hsp70 · HSP70 · Hsp70 · Hsp70Bbb · hsp70B · hsp70Bb-prime · Hsp70Bb · dHsp70 · CG31354)heat-shock protein 70⌘
D. melanogasterUniProtKB:Q9BIR7 · FB:FBgn0013279 (hsp-70 · Hsp70Bbc · HSP70 · hsp70Bc · dhsp70 · hsp70B · Hsp70Bd · CG6489 · Hsp70(87C) · Hsp70A7d · Hsp70Bc · hsp70 · Hsp70 · Hsp70B · Heat-shock-protein-70Bc · dHsp70 · Hsp70-BC)Protein 70 · hsp70 87C · heat-shock-protein 70bc · heat-shock protein 70 · 87C locus · heat shock 70 · Hsp 70⌘
D. melanogasterUniProtKB:P29843 · FB:FBgn0001216 (HSC-70 · BcDNA:RH49358 · 143191_at · CG8937 · HSC1 · Hsc70-1 · Hsc70 · hsc70 · HSC70 · dhsc70 · Hsc1)Heat shock protein cognate 1⌘
D. melanogasterUniProtKB:P11146 · FB:FBgn0001217 (HSC-70 · Hsc70.2 · HSC2 · hsc2 · Hsc70-2 · Hsc2 · CG7756 · Hsc70 · hsc70 · HSC70 · dhsc70)Heat shock protein cognate 2⌘
D. melanogasterUniProtKB:P29844 · FB:FBgn0001218 (HSC-70 · CG1579 · Bip · anon-WO0138581.7 · Hsc3 · l(1)G0111 · bip · Hsc70 · Grp78 · l(1)G0102 · hsc70 · Hsc3p · HSC70 · dhsc70 · l(1)G0407 · l(1)G0341 · hsc72 · hsc70-3 · l(1)G0292 · HSC3 · hsc3 · BiP · Hsc70-3 · l(1)G0466 · dmHsc72 · CG4147)heat shock cognate protein 3 · Heat shock protein cognate 3 · immunoglobulin binding protein⌘
D. melanogasterUniProtKB:P11147 · FB:FBgn0001219 (HSC-70 · l(3)j7A4 · HSC4 · Hsc70 · l(3)03550 · anon-WO0118547.237 · hsc70 · HSC70 · E(csp)1545 · scd · dhsc70 · scattered · hsc70-4 · BAP74 · hsc4 · Hsc4p · l(3)L3929 · hsp70 · E(nd)195 · i190 · CG4264 · bs17d06.y1 · Hsc4 · Hsc70-4)heat-shock protein 70 · Heat shock cognate 4 · hsp cognate 4 · heat shock cognate protein 70-4 · Heat shock protein cognate 4 · heat shock cognate protein 4⌘
D. melanogasterUniProtKB:P29845 · FB:FBgn0001220 (Hsc5 · HSC-70 · Hsc70-5 · Hsc70 · HSC5 · hsc70 · HSC70 · l(2)k04907 · CG8542 · dhsc70)Heat shock protein cognate 5⌘
D. melanogasterFB:FBgn0023529 (CG2918 · EG:25E8.1 · CT9894) · UniProtKB:O46067⌘
D. melanogasterFB:FBgn0035878 (CG7182) · UniProtKB:Q9VSI1⌘
D. melanogasterFB:FBgn0026418 (HSC-70 · 0318/20 · l(3)S148513 · l(3)S134802 · Hsc70Cb · anon-WO0118547.302 · l(3)07621 · Hsc70 · 0041/12 · 1348/02 · HSC70 · l(3)S134217 · 1485/13 · LD32772 · CG6603 · hsc70Cb · l(3)70Cb · l(3)70Ca · l(3)134217 · BEST:LD32772 · l(3)00082 · 1342/17 · l(3)148513) · UniProtKB:Q9XZT5⌘
E. coliUniProtKB:P0A6Y8 · ECOLI:EG10241-MONOMER (grpF · grpC · dnaK · DnaK · b0014 · groPC · seg · ECK0014 · groPAB · groPF)chaperone Hsp70; DNA biosynthesis; autoregulated heat shock proteins⌘
E. coliUniProtKB:P0A6Z1 · ECOLI:EG12130-MONOMER (hsc66 · ECK2523 · hscA · hsc · b2526 · HscA)chaperone, member of Hsp70 protein family⌘
E. coliUniProtKB:P77319 · ECOLI:G6357-MONOMER (b0650 · Hsc62 · hscC · ECK0643 · ybeW)Hsc62, Hsp70 family chaperone, binds to RpoD and inhibits transcription⌘
G. gallusNCBI:XP_416996 · ENTREZ:418802
G. gallusNCBI:XP_417113 · ENTREZ:418917
G. gallusNCBI:XP_423474 · ENTREZ:425753
G. gallusENTREZ:416339 · NCBI:XP_414655
G. gallusENTREZ:416183 · UniProtKB:Q5ZM98 (IPI00589568 · HSPA9 · Q5ZM98 · GRP75_CHICK · RCJMB04_2m8)Stress-70 protein, mitochondrial⌘
G. gallusENTREZ:396487 · UniProtKB:Q90593 (GRP78 · HSPA5 · GRP78_CHICK · Q90593 · IPI00590375)78 kDa glucose-regulated protein⌘
G. gallusENTREZ:423504 · UniProtKB:P08106 (HSP70_CHICK · P08106 · IPI00582091)Heat shock 70 kDa protein⌘
G. gallusENTREZ:395853 · UniProtKB:O73885 (HSPA8 · HSP7C_CHICK · IPI00603309 · HSC70 · O73885)Heat shock cognate 71 kDa protein⌘
G. gallusUniProtKB:Q5F3J8 (RCJMB04_15d24 · Q5F3J8 · IPI00573597) · ENTREZ:422496⌘
G. gallusUniProtKB:Q5F497 (RCJMB04_1o11 · Q5F497 · IPI00592330) · ENTREZ:418469⌘
G. gallusUniProtKB:Q5ZLK7 (Q5ZLK7 · IPI00570607 · RCJMB04_5l9) · ENTREZ:428251⌘
H. sapiensENSEMBL:ENSG00000113013 · UniProtKB:P38646 (GRP75_HUMAN · IPI00007765 · GRP75 · HSPA9 · HSPA9B · P38646)Stress-70 protein, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000044574 · UniProtKB:P11021 (GRP78 · HSPA5 · GRP78_HUMAN · IPI00003362 · P11021)78 kDa glucose-regulated protein⌘
H. sapiensENSEMBL:ENSG00000120694 · UniProtKB:Q92598 (KIAA0201 · IPI00218993 · Q92598 · HS105_HUMAN · HSP105 · HSP110 · IPI00514983 · HSPH1 · IPI00513743)Heat shock protein 105 kDa⌘
H. sapiensENSEMBL:ENSG00000204390 · UniProtKB:P34931 (P34931 · HSPA1L · IPI00301277 · HS71L_HUMAN)Heat shock 70 kDa protein 1L⌘
H. sapiensENSEMBL:ENSG00000164070 · UniProtKB:O95757 (HS74L_HUMAN · IPI00295485 · OSP94 · HSPA4L · APG1 · O95757)Heat shock 70 kDa protein 4L⌘
H. sapiensENSEMBL:ENSG00000155304 · UniProtKB:P48723 (HSP13_HUMAN · STCH · IPI00299299 · HSPA13 · P48723)Heat shock 70 kDa protein 13⌘
H. sapiensENSEMBL:ENSG00000215292 · UniProtKB:P08107 (HSPA1 · IPI00304925 · P08107 · HSPA1B · HSP71_HUMAN · HSPA1A)Heat shock 70 kDa protein 1⌘
H. sapiensENSEMBL:ENSG00000212860 · UniProtKB:P08107 (HSPA1 · IPI00304925 · P08107 · HSPA1B · HSP71_HUMAN · HSPA1A)Heat shock 70 kDa protein 1⌘
H. sapiensENSEMBL:ENSG00000204389 · UniProtKB:P08107 (HSPA1 · IPI00304925 · P08107 · HSPA1B · HSP71_HUMAN · HSPA1A)Heat shock 70 kDa protein 1⌘
H. sapiensENSEMBL:ENSG00000204388 · UniProtKB:P08107 (HSPA1 · IPI00304925 · P08107 · HSPA1B · HSP71_HUMAN · HSPA1A)Heat shock 70 kDa protein 1⌘
H. sapiensENSEMBL:ENSG00000212866 · UniProtKB:P08107 (HSPA1 · IPI00304925 · P08107 · HSPA1B · HSP71_HUMAN · HSPA1A)Heat shock 70 kDa protein 1⌘
H. sapiensENSEMBL:ENSG00000126803 · UniProtKB:P54652 (HSP72_HUMAN · P54652 · HSPA2 · IPI00007702)Heat shock-related 70 kDa protein 2⌘
H. sapiensENSEMBL:ENSG00000170606 · UniProtKB:P34932 (IPI00002966 · APG2 · P34932 · HSP74_HUMAN · HSPA4)Heat shock 70 kDa protein 4⌘
H. sapiensENSEMBL:ENSG00000173110 · UniProtKB:P17066 (IPI00339269 · P17066 · HSP76_HUMAN · HSPA6 · HSP70B')Heat shock 70 kDa protein 6⌘
H. sapiensENSEMBL:ENSG00000109971 · UniProtKB:P11142 (HSP7C_HUMAN · HSP73 · HSPA10 · HSPA8 · IPI00037070 · P11142 · HSC70 · IPI00003865)Heat shock cognate 71 kDa protein⌘
H. sapiensENSEMBL:ENSG00000187522 · UniProtKB:Q0VDF9 (HSP7E_HUMAN · HSP70L1 · IPI00292499 · HSP60 · HSPA14 · Q0VDF9)Heat shock 70 kDa protein 14⌘
H. sapiensENSEMBL:ENSG00000149428 · UniProtKB:Q9Y4L1 (IPI00000877 · HYOU1 · ORP150 · Q9Y4L1 · HYOU1_HUMAN)Hypoxia up-regulated protein 1⌘
M. musculusUniProtKB:P38647 · MGI:MGI:96245 (GRP75 · Hspa9 · mot-2 · CSA · PBP74 · Hsc74 · Hsp74a · mortalin · Hsp74 · Hspa9a · mthsp70)C3H-specific antigen · heat shock protein 9⌘
M. musculusUniProtKB:P20029 · MGI:MGI:95835 (78kDa · Bip · D2Wsu17e · Hspa5 · D2Wsu141e · Hsce70 · Grp78 · Sez7 · mBiP)heat shock protein 5⌘
M. musculusUniProtKB:Q61699 · MGI:MGI:105053 (HSP110 · Hsph1 · Hsp105 · hsp-E7I)heat shock 105kDa/110kDa protein 1⌘
M. musculusUniProtKB:Q61696 · MGI:MGI:96244 (Hsp70-3 · Hsp70.3 · Hspa1a)heat shock protein 1A⌘
M. musculusUniProtKB:P17879 · MGI:MGI:99517 (Hsp70-1 · Hsp70.1 · Hspa1b · HSP70A1 · Hsp70 · hsp68)heat shock protein 1B⌘
M. musculusUniProtKB:P16627 · MGI:MGI:96231 (Hsc70t · 70kDa · Msh5 · Hspa1l)heat shock protein 1-like⌘
M. musculusUniProtKB:P48722 · MGI:MGI:107422 (Osp94 · 94kDa · Hspa4l · APG-1)heat shock protein 4 like⌘
M. musculusUniProtKB:Q8BM72 · MGI:MGI:1309463 (60kDa · Hspa13 · Stch)heat shock protein 70 family, member 13⌘
M. musculusUniProtKB:P17156 · MGI:MGI:96243 (Hspa2 · 70kDa · Hsp70-2)heat shock protein 2⌘
M. musculusUniProtKB:Q61316 · MGI:MGI:1342292 (Hspa4 · Hsp70RY · 70kDa · APG-2 · Hsp110)heat shock protein 4⌘
M. musculusUniProtKB:P63017 · MGI:MGI:105384 (Hspa8 · Hsc70 · 70kDa · Hspa10 · Hsp73 · Hsc73 · Hsc71)heat shock protein 8⌘
M. musculusUniProtKB:Q99M31 · MGI:MGI:1354164 (Hspa14 · NST-1 · HSP70L1 · 70kDa · Hsp70-4)heat shock protein 14⌘
M. musculusUniProtKB:Q9JKR6 · MGI:MGI:108030 (Cab140 · Grp170 · CBP-140 · Orp150 · Hyou1)hypoxia up-regulated 1 · 140 kDa⌘
R. norvegicusNCBI:XP_575798 · RGD:1566128
R. norvegicusNCBI:XP_001055808 · RGD:1595502 (LOC680121)similar to heat shock protein 8⌘
R. norvegicusNCBI:XP_001053720 · RGD:1584764 (LOC679778)similar to heat shock protein 8⌘
R. norvegicusNCBI:XP_344009 · RGD:1560296
R. norvegicusNCBI:XP_001064420 · RGD:1592566 (Hspa8-ps1)heat shock protein 8, pseudogene 1⌘
R. norvegicusNCBI:XP_001053871 · RGD:1585936
R. norvegicusNCBI:XP_001056105 · RGD:1589489 (LOC679385)similar to heat shock protein 8⌘
R. norvegicusNCBI:XP_001066669 · RGD:1590785 (LOC498597)similar to hypothetical protein⌘
R. norvegicusRGD:1563999 · NCBI:XP_577286
R. norvegicusNCBI:XP_001064370 · RGD:1595873 (LOC307023)similar to heat shock protein 8⌘
R. norvegicusNCBI:XP_001070485 · RGD:1586392 (LOC689908)similar to heat shock protein 8⌘
R. norvegicusNCBI:XP_001072458 · RGD:1559849
R. norvegicusNCBI:XP_224824 · RGD:1561628 (RGD1561628)similar to Chain A, T13s Mutant Of Bovine 70 Kilodalton Heat Shock Protein⌘
R. norvegicusUniProtKB:P48721 · RGD:1311806 (Hspa9)heat shock protein 9⌘
R. norvegicusUniProtKB:P06761 · RGD:2843 (Hspa5)heat shock protein 5⌘
R. norvegicusUniProtKB:Q66HA8 · RGD:1311609 (Hsph1)heat shock 105kDa/110kDa protein 1⌘
R. norvegicusUniProtKB:P55063 · RGD:1595925 (Hspa1l)heat shock protein 1-like⌘
R. norvegicusUniProtKB:O35162 · RGD:3775 (Hspa13)heat shock protein 70kDa family, member 13⌘
R. norvegicusRGD:2840 (Hspa1b) · UniProtKB:Q07439 (Hspa2 · Hspa1b · Q07439 · Hsp70-1 · IPI00196751 · Hspa1a · Hsp70-2 · Hspa1 · HSP71_RAT)heat shock protein 1B · Heat shock 70 kDa protein 1A/1B⌘⌘
R. norvegicusRGD:1593284 (Hspa1a) · UniProtKB:Q07439 (Hspa2 · Hspa1b · Q07439 · Hsp70-1 · IPI00196751 · Hspa1a · Hsp70-2 · Hspa1 · HSP71_RAT)heat shock protein 1A · Heat shock 70 kDa protein 1A/1B⌘⌘
R. norvegicusUniProtKB:P14659 · RGD:620664 (Hspa2)heat shock protein 2⌘
R. norvegicusUniProtKB:O88600 · RGD:628878 (Hspa4)heat shock protein 4⌘
R. norvegicusUniProtKB:P63018 · RGD:621725 (Hspa8)heat shock protein 8⌘
R. norvegicusUniProtKB:Q6AYB4 · RGD:1303296 (Hspa14)heat shock protein 14⌘
R. norvegicusRGD:621146 (Hyou1) · UniProtKB:Q63617 (Q63617 · HYOU1_RAT · IPI00210975 · Orp150 · Hyou1)hypoxia up-regulated 1 · Hypoxia up-regulated protein 1⌘⌘
S. cerevisiaeUniProtKB:P16474 · SGD:S000003571 (GRP78 · YJL034W · KAR2)ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins⌘
S. cerevisiaeUniProtKB:P10591 · SGD:S000000004 (SSA1 · YG100 · YAL005C)ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport⌘
S. cerevisiaeUniProtKB:P10592 · SGD:S000003947 (YG102 · YLL024C · SSA2)ATP binding protein involved in protein folding and vacuolar import of proteins⌘
S. cerevisiaeUniProtKB:P09435 · SGD:S000000171 (YBL075C · YG106 · SSA3)ATPase involved in protein folding and the response to stress⌘
S. cerevisiaeUniProtKB:P22202 · SGD:S000000905 (YER103W · SSA4 · YG107)Heat shock protein that is highly induced upon stress⌘
S. cerevisiaeUniProtKB:P11484 · SGD:S000002388 (SSB1 · YDL229W · YG101)Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p⌘
S. cerevisiaeUniProtKB:P40150 · SGD:S000005153 (YNL209W · YG103 · SSB2)Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p⌘
S. cerevisiaeUniProtKB:P12398 · SGD:S000003806 (mtHSP70 · ENS1 · YJR045C · SSC1)Mitochondrial matrix ATPase, subunit of the presequence translocase-associated protein import motor (PAM) and of SceI endonuclease⌘
S. cerevisiaeUniProtKB:P32590 · SGD:S000000373 (YBR169C · SSE2)Member of the heat shock protein 70 (HSP70) family⌘
S. cerevisiaeUniProtKB:P39987 · SGD:S000000756 (YEL030W · SSC3 · ECM10)Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner⌘
S. cerevisiaeUniProtKB:P32589 · SGD:S000006027 (LPG3 · YPL106C · MSI3 · SSE1)ATPase that is a component of the heat shock protein Hsp90 chaperone complex⌘
S. cerevisiaeUniProtKB:Q05931 · SGD:S000004361 (YLR369W · SSC2 · SSQ1 · SSH1)Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia⌘
S. cerevisiaeUniProtKB:P36016 · SGD:S000001556 (SSI1 · YKL073W · LHS1 · CER1)Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding⌘
S. cerevisiaeUniProtKB:P38788 · SGD:S000001106 (PDR13 · SSZ1 · YHR064C)Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit⌘
S. pombeGeneDB_Spombe:SPAC22A12.15c (bip · SPAC22A12.15c · bip1 · BiP) · UniProtKB:P36604⌘
S. pombeUniProtKB:Q10265 · GeneDB_Spombe:SPAC13G7.02c (SPAC13G7.02c · ssa1)heat shock protein Ssa1⌘
S. pombeUniProtKB:O59855 · GeneDB_Spombe:SPCC1739.13 (ssa2 · SPCC1739.13)heat shock protein Ssa2⌘
S. pombeUniProtKB:Q10284 · GeneDB_Spombe:SPBC1709.05 (sks2 · hsc1 · SPBC1709.05)heat shock protein Sks2⌘
S. pombeUniProtKB:O59838 · GeneDB_Spombe:SPAC110.04c (SPAC110.04c · pss1 · SPAP14E8.01c · ssp1)heat shock protein Pss1⌘
S. pombeUniProtKB:P22774 · GeneDB_Spombe:SPAC664.11 (ssc1 · ssp1 · SPAC664.11)mitochondrial heat shock protein Hsp70⌘
S. pombeUniProtKB:Q10061 · GeneDB_Spombe:SPAC1F5.06 (SPAC1F5.06)heat shock protein Lhs1⌘
S. pombeUniProtKB:P87142 · GeneDB_Spombe:SPAC57A7.12 (SPAC57A7.12)heat shock protein Pdr13⌘
ProteinPublicationCurator Notes
UniProtKB:P38788 · SGD:S000001106PMID:16002468 Otto H, et al. The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10064-9.The H. sapiens protein Q0VDF9 complements a homologous mutation in S. cerevisiae. Human Hsp70L1 complements a yeast ssz1 mutant. Together, human Hsp70L1 and MPP11 complement a yeast ssz1 zuo1 double mutant.
UniProtKB:P09435 · SGD:S000000171PMID:15209506 Mosser DD, et al. Saccharomyces cerevisiae Hsp104 enhances the chaperone capacity of human cells and inhibits heat stress-induced proapoptotic signaling. Biochemistry. 2004 Jun 29;43(25):8107-15.The S. cerevisiae protein SSA3 was expressed in H. sapiens, but complementation was not directly tested. This paper shows functional expression of yeast HSP104 in human cells and interaction with human HSP70 proteins, but not complementation.
UniProtKB:P12398 · SGD:S000003806PMID:9324254 Deloche O, et al. Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli. J Bacteriol. 1997 Oct;179(19):6066-75.The S. cerevisiae protein SSC1 does not complement a homologous mutation in E. coli. This paper describes a biochemical and genetic analysis of yeast Ssc1p, Mdj1p, and Mge1p in E. coli.
UniProtKB:P09435 · SGD:S000000171PMID:10677504 Krobitsch S, et al. Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1589-94.The H. sapiens protein Ht (protein ID unknown) was expressed in S. cerevisiae, but complementation was not directly tested. This paper describes the characterization of variant truncated forms of the human Huntington's disease protein expressed in yeast.
UniProtKB:P16474 · SGD:S000003571PMID:16232647 Kasuya T, et al. Cloning and characterization of the bipA gene encoding ER chaperone BiP from Aspergillus oryzae. J Biosci Bioeng. 1999;88(5):472-8.The A. oryzae protein bipA complements a homologous mutation in S. cerevisiae. This paper shows partial complementation of the yeast kar2 mutant by Aspergillus oryzae bipA.
UniProtKB:P09435 · SGD:S000000171PMID:12462526 Sandini S, et al. Gene expression of 70 kDa heat shock protein of Candida albicans: transcriptional activation and response to heat shock. Med Mycol. 2002 Oct;40(5):471-8.The C. albicans protein CaHSP70 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows heterologous expression of only the C. albicans CaHSP70 promoter fused to a lacZ reporter construct in S. cerevisiae.
UniProtKB:P16474 · SGD:S000003571PMID:16889384 Zhang W, et al. Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins. Biotechnol Prog. 2006 Jul-Aug;22(4):1090-5.The S. cerevisiae protein KAR2 was expressed in P. pastoris, but complementation was not directly tested. This paper shows heterologous overexpression of S. cerevisiae KAR2 in P. pastoris.
UniProtKB:P10591 · SGD:S000000004PMID:16889384 Zhang W, et al. Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins. Biotechnol Prog. 2006 Jul-Aug;22(4):1090-5.The S. cerevisiae protein SSA1 was expressed in P. pastoris, but complementation was not directly tested. This paper shows heterologous overexpression of S. cerevisiae SSA1 in P. pastoris.
UniProtKB:P16474 · SGD:S000003571PMID:10430031 Amshoff C, et al. Cycloheximide, a new tool to dissect specific steps in ER-associated degradation of different substrates. Biol Chem. 1999 Jun;380(6):669-77.The M. musculus protein murine mu (protein ID unknown) was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows heterologous expression of murine mu in yeast, not complementation.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
UniProtKB:P10591 · SGD:S000000004#180300 RHEUMATOID ARTHRITIS; RA;;RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO
SGD Disease Papers (8)
UniProtKB:P10592 · SGD:S000003947PMID:16973603 Dehay B and Bertolotti A (2006) Critical Role of the Proline-rich Region in Huntingtin for Aggregation and Cytotoxicity in Yeast. J Biol Chem 281(47):35608-15
PMID:11796717 Bao YP, et al. (2002) Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. J Biol Chem 277(14):12263-9
PMID:10859365 Muchowski PJ, et al. (2000) Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils. Proc Natl Acad Sci U S A 97(14):7841-6
UniProtKB:P09435 · SGD:S000000171PMID:11796717 Bao YP, et al. (2002) Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. J Biol Chem 277(14):12263-9
UniProtKB:P22202 · SGD:S000000905PMID:11796717 Bao YP, et al. (2002) Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. J Biol Chem 277(14):12263-9
UniProtKB:Q05931 · SGD:S000004361PMID:11796717 Bao YP, et al. (2002) Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. J Biol Chem 277(14):12263-9
UniProtKB:Q05931 · SGD:S000004361PMID:17331979 Shan Y, et al. (2007) Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones. Hum Mol Genet 16(8):929-41
PMID:11689493 Huynen MA, et al. (2001) The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly. Hum Mol Genet 10(21):2463-8
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