This family has 32 members: 11 Saccharomyces cerevisiae, 21 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| S. cerevisiae | UniProtKB:P53943 · SGD:S000005009 (AQR1 · YNL065W) | Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine |  |
| S. cerevisiae | UniProtKB:P38124 · SGD:S000000212 (FLR1 · YBR008C) | Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs | |
| S. cerevisiae | UniProtKB:Q07824 · SGD:S000003951 (YLL028W · TPO1) | Polyamine transporter that recognizes spermine, putrescine, and spermidine | |
| S. cerevisiae | UniProtKB:P53283 · SGD:S000003370 (TPO2 · YGR138C) | Polyamine transport protein specific for spermine | |
| S. cerevisiae | UniProtKB:Q06451 · SGD:S000006360 (TPO3 · YPR156C) | Polyamine transport protein specific for spermine | |
| S. cerevisiae | UniProtKB:Q12256 · SGD:S000005799 (YOR273C · TPO4) | Polyamine transport protein, recognizes spermine, putrescine, and spermidine | |
| S. cerevisiae | UniProtKB:P38125 · SGD:S000000384 (YBR180W · DTR1) | Putative dityrosine transporter, required for spore wall synthesis | |
| S. cerevisiae | UniProtKB:P38227 · SGD:S000000247 (AQR2 · QDR3 · YBR043C) | Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin | |
| S. cerevisiae | UniProtKB:P38776 · SGD:S000001090 (YHR048W · YHK8) | Presumed antiporter of the DHA1 family of multidrug resistance transporters | |
| S. cerevisiae | UniProtKB:P40475 · SGD:S000001382 (QDR1 · YIL120W) | Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ketoconazole, fluconazole, and barban | |
| S. cerevisiae | UniProtKB:P40474 · SGD:S000001383 (YIL121W · QDR2) | Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin | |
| S. pombe | UniProtKB:P33532 · GeneDB_Spombe:SPAC17A2.01 (SPAC1B1.05 · SPAC17A2.01 · bsu1) | high-affinity import carrier for pyridoxine, pyridoxal, and pyridoxamine Bsu1 | |
| S. pombe | UniProtKB:O94528 · GeneDB_Spombe:SPBC609.04 (caf5 · SPBC609.04) | spermine family transmembrane transporter Caf5 | |
| S. pombe | UniProtKB:Q10487 · GeneDB_Spombe:SPAC17C9.16c (SPAC9E9.16 · SPAC17C9.16c) | MFS family transmembrane transporter Mfs1 | |
| S. pombe | UniProtKB:Q10084 · GeneDB_Spombe:SPAC11D3.05 (SPAC11D3.05 · mfs2) | MFS family membrane transporter | |
| S. pombe | UniProtKB:O43081 · GeneDB_Spombe:SPBC947.06c (SPBC947.06c) | spermidine family transporter | |
| S. pombe | UniProtKB:Q9USN4 · GeneDB_Spombe:SPCC1529.01 (SPCC1529.01 · SPCC794.14) | membrane transporter | |
| S. pombe | UniProtKB:Q9HDX4 · GeneDB_Spombe:SPAPB1A11.01 (SPAPB24D3.11 · SPAPB1A11.01) | membrane transporter | |
| S. pombe | UniProtKB:O74829 · GeneDB_Spombe:SPBC530.15c (SPBC530.15c · SPBC661.01) | spermidine family transporter | |
| S. pombe | UniProtKB:O59698 · GeneDB_Spombe:SPBC36.01c (SPBC36.01c) | spermidine family transporter | |
| S. pombe | UniProtKB:O59699 · GeneDB_Spombe:SPBC36.02c (SPBC36.02c) | spermidine family transporter | |
| S. pombe | UniProtKB:O59700 · GeneDB_Spombe:SPBC36.03c (SPBC36.03c) | spermidine family transporter | |
| S. pombe | UniProtKB:O59738 · GeneDB_Spombe:SPBC530.02 (SPBC530.02) | membrane transporter | |
| S. pombe | UniProtKB:O59814 · GeneDB_Spombe:SPCC794.04c (SPCC794.04c) | membrane transporter | |
| S. pombe | UniProtKB:O59833 · GeneDB_Spombe:SPCC965.13 (SPCC965.13) | membrane transporter | |
| S. pombe | UniProtKB:O74899 · GeneDB_Spombe:SPCC576.17c (SPCC576.17c) | membrane transporter | |
| S. pombe | UniProtKB:O94343 · GeneDB_Spombe:SPBC1271.10c (SPBC1271.10c) | membrane transporter | |
| S. pombe | UniProtKB:Q7Z9I0 · GeneDB_Spombe:SPBC409.08 (SPBC409.08) | spermine family transporter | |
| S. pombe | UniProtKB:Q9P3E8 · GeneDB_Spombe:SPBPB2B2.16c (SPBPB2B2.16c) | MFS family membrane transporter | |
| S. pombe | UniProtKB:Q9P3E8 · GeneDB_Spombe:SPAC750.02c (SPAC750.02c) | membrane transporter | |
| S. pombe | UniProtKB:Q9P3V5 · GeneDB_Spombe:SPBC1348.05 (SPBC1348.05) | membrane transporter | |
| S. pombe | UniProtKB:Q9Y7S4 · GeneDB_Spombe:SPCC569.05c (SPCC569.05c) | spermidine family transporter | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| SGD Disease Papers (3) | |
|---|---|
| UniProtKB:P38227 · SGD:S000000247 |  17156010 Alenquer M, et al. (2006) Adaptive response to the antimalarial drug artesunate in yeast involves Pdr1p/Pdr3p-mediated transcriptional activation of the resistance determinants TPO1 and PDR5. FEMS Yeast Res 6(8):1130-9 |
| UniProtKB:P40474 · SGD:S000001383 | 15649438 Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 |
| UniProtKB:P40474 · SGD:S000001383 | 15649438 Tenreiro S, et al. (2005) The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun 327(3):952-9 |