P-POD: Princeton Protein Orthology Database: GO3/Jaccard675

This family has 34 members: 2 Arabidopsis thaliana, 5 Caenorhabditis elegans, 4 Danio rerio, 3 Dictyostelium discoideum, 2 Drosophila melanogaster, 1 Escherichia coli, 3 Gallus gallus, 4 Homo sapiens, 4 Mus musculus, 4 Rattus norvegicus, 2 Saccharomyces cerevisiae.

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34 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2020138 (F20D21_17 · F20D21.17 · AT1G54350) · NCBI:NP_175837.2⌘
A. thalianaNCBI:NP_568072.1 · TAIR:locus:2139990 (PXA1 · AT4G39850 · COMATOSE · T5J17_20 · T5J17.20 · CTS · PED3)PEROXISOMAL ABC TRANSPORTER 1 · PEROXISOME DEFECTIVE 3⌘
C. elegansWB:WBGene00004061 (pmp-4 · T02D1.5) · UniProtKB:O45730⌘
C. elegansWB:WBGene00004058 (C44B7.8 · pmp-1) · UniProtKB:Q18597⌘
C. elegansWB:WBGene00004059 (C44B7.9 · pmp-2) · UniProtKB:Q18598⌘
C. elegansWB:WBGene00004060 (pmp-3 · C54G10.3) · UniProtKB:Q18843⌘
C. elegansWB:WBGene00004062 (T10H9.5 · pmp-5) · UniProtKB:Q86S26⌘
D. rerioENSEMBL:ENSDARP00000076957
D. rerioENSEMBL:ENSDARP00000007440
D. rerioZFIN:ZDB-GENE-060929-396 (zgc:153503) · UniProtKB:Q08C64⌘
D. rerioUniProtKB:Q803I6 · ZFIN:ZDB-GENE-040426-2868 (abcd3a)ATP-binding cassette, sub-family D (ALD), member 3a⌘
D. discoideumUniProtKB:Q54W19 · dictyBase:DDB_G0279917 (abcD1)ABC transporter D family protein⌘
D. discoideumUniProtKB:Q54W20 · dictyBase:DDB_G0279919 (abcD3)ABC transporter D family protein⌘
D. discoideumUniProtKB:Q8T8P3 · dictyBase:DDB_G0293194 (abcD2)ABC transporter D family protein⌘
D. melanogasterUniProtKB:Q7JUN3 · FB:FBgn0039890 (CG2316)⌘
D. melanogasterFB:FBgn0031069 (CG12703 · i17) · UniProtKB:Q9VWC8⌘
E. coliUniProtKB:P31826 · ECOLI:YDDA-MONOMER (YddA · b1496 · ECK1490 · yddA)⌘
G. gallusNCBI:XP_415938 · ENTREZ:417694
G. gallusNCBI:XP_421264 · ENTREZ:423349
G. gallusUniProtKB:Q5F4B9 (Q5F4B9 · RCJMB04_1c12 · IPI00602273) · ENTREZ:424487⌘
H. sapiensENSEMBL:ENSG00000101986 · UniProtKB:P33897 (ABCD1_HUMAN · IPI00291373 · ABCD1 · ALD · P33897)ATP-binding cassette sub-family D member 1⌘
H. sapiensENSEMBL:ENSG00000173208 · UniProtKB:Q9UBJ2 (ALD1 · ALDRP · ALDR · Q9UBJ2 · ABCD2_HUMAN · ABCD2 · IPI00002618 · ALDL1)ATP-binding cassette sub-family D member 2⌘
H. sapiensENSEMBL:ENSG00000117528 · UniProtKB:P28288 (ABCD3 · ABCD3_HUMAN · P28288 · IPI00185503 · PMP70 · PXMP1 · IPI00002372 · IPI00884932)ATP-binding cassette sub-family D member 3⌘
H. sapiensENSEMBL:ENSG00000119688 · UniProtKB:O14678 (IPI00023165 · O14678 · ABCD4_HUMAN · PXMP1L · ABCD4)ATP-binding cassette sub-family D member 4⌘
M. musculusUniProtKB:P48410 · MGI:MGI:1349215 (ALDP · Aldgh · Ald · Abcd1)ATP-binding cassette, sub-family D (ALD), member 1⌘
M. musculusUniProtKB:Q61285 · MGI:MGI:1349467 (ABC39 · ALDR · ALDL1 · Abcd2)adrenoleukodystrophy related · ATP-binding cassette, sub-family D (ALD), member 2⌘
M. musculusUniProtKB:P55096 · MGI:MGI:1349216 (Abcd3 · Pxmp1 · PMP70)ATP-binding cassette, sub-family D (ALD), member 3⌘
M. musculusUniProtKB:O89016 · MGI:MGI:1349217 (Abcd4 · Pxmp1l · P69r)ATP-binding cassette, sub-family D (ALD), member 4⌘
R. norvegicusNCBI:XP_001059399 · RGD:1562128 (Abcd1)ATP-binding cassette, sub-family D (ALD), member 1⌘
R. norvegicusUniProtKB:Q9QY44 · RGD:69244 (Abcd2)ATP-binding cassette, sub-family D (ALD), member 2⌘
R. norvegicusUniProtKB:P16970 · RGD:2007 (Abcd3)ATP-binding cassette, sub-family D (ALD), member 3⌘
R. norvegicusUniProtKB:Q5FWT4 · RGD:1307273 (Abcd4)ATP-binding cassette, sub-family D (ALD), member 4⌘
S. cerevisiaeUniProtKB:P41909 · SGD:S000006068 (PAT2 · PXA1 · PAL1 · SSH2 · YPL147W · LPI1)Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes⌘
S. cerevisiaeUniProtKB:P34230 · SGD:S000001671 (PAT1 · YKL188C · PXA2)Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (3)
ENSEMBL:ENSG00000101986 · UniProtKB:P33897#300100 ADRENOLEUKODYSTROPHY; ALD;;ADDISON DISEASE AND CEREBRAL SCLEROSIS;;ADRENOMYELONEUROPATHY; AMN;;SIEMERLING-CREUTZFELDT DISEASE;;BRONZE SCHILDER DISEASE;;MELANODERMIC LEUKODYSTROPHY
ENSEMBL:ENSG00000117528 · UniProtKB:P28288#300475 CONTIGUOUS ABCD1/DXS1375E DELETION SYNDROME;;CADDS
UniProtKB:P41909 · SGD:S000006068+170995 ATP-BINDING CASSETTE, SUBFAMILY D, MEMBER 3; ABCD3;;PEROXISOMAL MEMBRANE PROTEIN 1; PXMP1;;PEROXISOMAL MEMBRANE PROTEIN, 70-KD; PMP70ZELLWEGER SYNDROME 2, INCLUDED; ZWS2, INCLUDED
SGD Disease Papers (9)
UniProtKB:P34230 · SGD:S000001671PMID:9395310 Verleur N, et al. (1997) Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system. Eur J Biochem 249(3):657-61
PMID:8993619 Shani N, et al. (1996) An S. cerevisiae peroxisomal transporter, orthologous to the human adrenoleukodystrophy protein, appears to be a heterodimer of two half ABC transporters: Pxa1p and Pxa2p. Ann N Y Acad Sci 804:770-2
PMID:8876235 Shani N and Valle D (1996) A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. Proc Natl Acad Sci U S A 93(21):11901-6
PMID:8647887 Swartzman EE, et al. (1996) The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae. J Cell Biol 132(4):549-63
PMID:8621506 Shani N, et al. (1996) Characterization and analysis of conserved motifs in a peroxisomal ATP-binding cassette transporter. J Biol Chem 271(15):8725-30
PMID:7597071 Shani N, et al. (1995) PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene. Proc Natl Acad Sci U S A 92(13):6012-6
UniProtKB:P34230 · SGD:S000001671PMID:9395310 Verleur N, et al. (1997) Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system. Eur J Biochem 249(3):657-61
PMID:8621506 Shani N, et al. (1996) Characterization and analysis of conserved motifs in a peroxisomal ATP-binding cassette transporter. J Biol Chem 271(15):8725-30
PMID:7941751 Bossier P, et al. (1994) The yeast YKL741 gene situated on the left arm of chromosome XI codes for a homologue of the human ALD protein. Yeast 10(5):681-6
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