This family has 36 members: 5 Arabidopsis thaliana, 3 Caenorhabditis elegans, 4 Danio rerio, 3 Dictyostelium discoideum, 3 Drosophila melanogaster, 3 Gallus gallus, 3 Homo sapiens, 3 Mus musculus, 3 Rattus norvegicus, 3 Saccharomyces cerevisiae, 3 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | NCBI:NP_193902.1 · TAIR:locus:2119013 (EMB1989 · NRPB2 · RPB2 · AT4G21710 · F17L22_170 · F17L22.170) | EMBRYO DEFECTIVE 1989 |  |
| A. thaliana | NCBI:NP_188437.2 · TAIR:locus:2092682 (NRPD2b · MRC8.7 · AT3G18090) | | |
| A. thaliana | NCBI:NP_199327.4 · TAIR:locus:2153323 (AT5G45140 · NRPC2 · K18C1_1 · K18C1.1) | | |
| A. thaliana | NCBI:NP_564341.2 · TAIR:locus:2019272 (AT1G29940 · F1N18.2 · NRPA2) | | |
| A. thaliana | NCBI:NP_189020.2 · TAIR:locus:2095233 (NRPE2 · DMS2 · DRD2 · NRPD2 · NRPD2A · MYM9.13 · AT3G23780) | DEFECTIVE IN MERISTEM SILENCING 2 | |
| C. elegans | WB:WBGene00016140 (C26E6.4 · rpb-2) · UniProtKB:Q10578 | | |
| C. elegans | WB:WBGene00017300 (F09F7.3) · UniProtKB:Q27492 | | |
| C. elegans | WB:WBGene00008781 (F14B4.3) · UniProtKB:Q27493 | | |
| D. rerio | ENSEMBL:ENSDARG00000062915 · UniProtKB:A2BG99 | ||
| D. rerio | UniProtKB:Q4V967 · ENSEMBL:ENSDARG00000068626 | ||
| D. rerio | UniProtKB:Q4V967 · ENSEMBL:ENSDARG00000068942 | ||
| D. rerio | UniProtKB:Q6DRH1 · ZFIN:ZDB-GENE-041008-1 (polr2b) | polymerase (RNA) II (DNA directed) polypeptide B | |
| D. discoideum | UniProtKB:Q54BM1 · dictyBase:DDB_G0293560 (rpa2) | RNA polymerase I, second largest subunit | |
| D. discoideum | UniProtKB:Q54J75 · dictyBase:DDB_G0288257 (rpb2) | RNA polymerase II core subunit, RNA polymerase II, second largest subunit | |
| D. discoideum | UniProtKB:Q54IZ9 · dictyBase:DDB_G0288449 (rpc2) | RNA polymerase III, second largest subunit | |
| D. melanogaster | UniProtKB:P20028 · FB:FBgn0003278 (RpI135 · RpIII135 · CG4033 · l(2)k16513 · DmRP135 · RP135) | RNA polymerase I · RNA polymerase I 135kD subunit | |
| D. melanogaster | UniProtKB:P08266 · FB:FBgn0003276 (RP140 · RpII140 · RNApolII · RPII140 · H5 · DmRP140 · PolII · Rpll140 · RNAP · CG3180 · polII · wimp · II · rpII140/wimp · PolIIc · l(3)RplII140 · RpII140[wimp]) | Pol II · RNA pol II · RNA polymerase subunit IIc · subunit IIc of RNA Pol II · RNA polymeraseII-140 kd subunit · 150kDa polypeptide · RNA polymerase II 140kD subunit · RNA pol II second largest subunit · Pol IIc · pol II · RNA polymerase II · RNA Pol II second largest subunit · RNA Pol II · RNA Pol IIc · RNAP II · RNA polII · RNA polymerase II second largest subunit | |
| D. melanogaster | UniProtKB:P25167 · FB:FBgn0004463 (DmRP128 · CG8344 · RP128 · RpIII128) | RNA polymerase IIIb · RNA polymerase III · RNA polymerase III 128kD subunit | |
| G. gallus | NCBI:XP_416307 · ENTREZ:418071 | ||
| G. gallus | NCBI:XP_415007 · ENTREZ:416710 | ||
| G. gallus | ENTREZ:422621 · UniProtKB:Q5ZMN9 (Q5ZMN9 · IPI00823005 · RCJMB04_1i14) | DNA-directed RNA polymerase | |
| H. sapiens | ENSEMBL:ENSG00000125630 · UniProtKB:Q9H9Y6 (RPA2_HUMAN · IPI00418797 · POLR1B · IPI00026445 · Q9H9Y6) | DNA-directed RNA polymerase I subunit RPA2 | |
| H. sapiens | ENSEMBL:ENSG00000047315 · UniProtKB:P30876 (POLR2B · IPI00027808 · P30876 · RPB2_HUMAN) | DNA-directed RNA polymerase II subunit RPB2 | |
| H. sapiens | ENSEMBL:ENSG00000013503 · UniProtKB:Q9NW08 (RPC2_HUMAN · Q9NW08 · POLR3B · IPI00301346) | DNA-directed RNA polymerase III subunit RPC2 | |
| M. musculus | UniProtKB:P70700 · MGI:MGI:108014 (Rpo1-2 · RPA2 · RPA116 · Polr1b · 128kDa) | polymerase (RNA) I polypeptide B | |
| M. musculus | UniProtKB:Q8CFI7 · MGI:MGI:2388280 (RPB140 · RPB2 · POL2RB · Polr2b) | polymerase (RNA) II (DNA directed) polypeptide B | |
| M. musculus | UniProtKB:P59470 · MGI:MGI:1917678 (RPC2 · Polr3b) | polymerase (RNA) III (DNA directed) polypeptide B | |
| R. norvegicus | NCBI:XP_214021 · RGD:1309477 (Polr2b) | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | |
| R. norvegicus | NCBI:XP_343189 · RGD:1565311 (Polr3b) | polymerase (RNA) III (DNA directed) polypeptide B | |
| R. norvegicus | UniProtKB:O54888 · RGD:620822 (Polr1b) | polymerase (RNA) I polypeptide B | |
| S. cerevisiae | UniProtKB:P22138 · SGD:S000006214 (RPA2 · YPR010C · RPA135 · RRN2 · SRP3) | RNA polymerase I subunit A135 | |
| S. cerevisiae | UniProtKB:P08518 · SGD:S000005677 (RPO22 · YOR151C · SIT2 · RPB150 · RPB2 · SOH2) | RNA polymerase II second largest subunit B150, part of central core | |
| S. cerevisiae | UniProtKB:P22276 · SGD:S000005733 (RPC2 · PDS2 · RPC128 · YOR207C · RET1) | Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs | |
| S. pombe | UniProtKB:Q9P7X8 · GeneDB_Spombe:SPBP23A10.07 (rpa2 · SPBP23A10.07) | DNA-directed RNA polymerase I complex subunit Rpa2 | |
| S. pombe | UniProtKB:Q02061 · GeneDB_Spombe:SPAC23G3.01 (SPAC521.06 · SPAC23G3.01 · rpb2) | DNA-directed RNA polymerase II complex subunit Rpb2 | |
| S. pombe | UniProtKB:Q10233 · GeneDB_Spombe:SPAC4G9.08c (rpc2 · SPAC4G9.08c) | DNA-directed RNA polymerase III complex subunit Rpc2 | |
| Protein | Publication | Curator Notes | |
|---|---|---|---|
| UniProtKB:P22276 · SGD:S000005733 |  16877568 Proshkina GM, et al. Ancient origin, functional conservation and fast evolution of DNA-dependent RNA polymerase III. Nucleic Acids Res. 2006;34(13):3615-24. | The S. pombe protein Rpc2 does not complement a homologous mutation in S. cerevisiae. |
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |