This family has 37 members: 7 Arabidopsis thaliana, 3 Caenorhabditis elegans, 5 Danio rerio, 2 Dictyostelium discoideum, 3 Drosophila melanogaster, 2 Gallus gallus, 3 Homo sapiens, 3 Mus musculus, 3 Rattus norvegicus, 3 Saccharomyces cerevisiae, 3 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | TAIR:locus:2087755 (MBK21.1 · AT3G12860) · NCBI:NP_187892.2 |  | |
| A. thaliana | NCBI:NP_001031260.1 · TAIR:locus:2016134 (AT1G70400 · F17O7_6 · F17O7.6) | | |
| A. thaliana | NCBI:NP_198064.1 · TAIR:locus:2181211 (T21B4.30 · T21B4_30 · AT5G27120) | | |
| A. thaliana | NCBI:NP_187157.1 · TAIR:locus:2096214 (T12H1.2 · T12H1_2 · AT3G05060) | | |
| A. thaliana | NCBI:NP_176007.1 · TAIR:locus:2205270 (T6H22_10 · AT1G56110 · T6H22.10 · NOP56) | NOP56-LIKE PROTEIN · Arabidopsis homolog of nucleolar protein Nop56 | |
| A. thaliana | NCBI:NP_564754.1 · TAIR:locus:2195698 (emb1220 · T13D8.6 · T13D8_6 · AT1G60170) | embryo defective 1220 | |
| A. thaliana | NCBI:NP_198066.1 · TAIR:locus:2181236 (T21B4.50 · AT5G27140 · T21B4_50) | | |
| C. elegans | WB:WBGene00010627 (K07C5.4) · UniProtKB:Q21276 | | |
| C. elegans | WB:WBGene00020915 (W01B11.3 · nol-5) · UniProtKB:O45012 | | |
| C. elegans | WB:WBGene00022458 (Y110A7A.8) · UniProtKB:Q9N592 | | |
| D. rerio | ENSEMBL:ENSDARP00000092853 | ||
| D. rerio | UniProtKB:Q7SXM7 · ZFIN:ZDB-GENE-040426-1561 (prpf31) | PRP31 pre-mRNA processing factor 31 homolog (yeast) | |
| D. rerio | ZFIN:ZDB-GENE-040109-1 · UniProtKB:Q6DRE5 | ||
| D. rerio | ENSEMBL:ENSDARG00000007204 · UniProtKB:Q6P6X6 | ||
| D. rerio | UniProtKB:Q6P6X6 · ENSEMBL:ENSDARG00000058337 | ||
| D. discoideum | UniProtKB:Q54MT2 · dictyBase:DDB_G0285679 (nol5a) | NOP5 family protein | |
| D. discoideum | dictyBase:DDB_G0268098 · UniProtKB:Q55FI4 | ||
| D. melanogaster | FB:FBgn0038964 (CG13849 · FBgn0038964 · Nop56) · UniProtKB:Q95WY3 | | |
| D. melanogaster | FB:FBgn0026196 (Nop5 · FBgn0026196 · nop5 · CG10206 · 2/30 · Dnop5 · DNOP5) · UniProtKB:Q9VM69 | | |
| D. melanogaster | UniProtKB:Q9VUM1 · FB:FBgn0036487 (CG6876 · anon-EST:Liang-2.38) | clone 2.38 | |
| G. gallus | NCBI:XP_421942 · ENTREZ:424087 | ||
| G. gallus | UniProtKB:Q5ZMD0 · ENTREZ:426574 | ||
| H. sapiens | ENSEMBL:ENSG00000101361 · UniProtKB:O00567 (IPI00411937 · O00567 · NOL5A_HUMAN · NOP56 · NOL5A) | Nucleolar protein 5A | |
| H. sapiens | ENSEMBL:ENSG00000055044 · UniProtKB:Q9Y2X3 (HSPC120 · NOP5 · IPI00006379 · NOL5_HUMAN · NOL5 · Q9Y2X3) | Nucleolar protein 5 | |
| H. sapiens | ENSEMBL:ENSG00000105618 · UniProtKB:Q8WWY3 (PRPF31 · IPI00292000 · PRP31_HUMAN · IPI00167198 · PRP31 · IPI00738596 · Q8WWY3) | U4/U6 small nuclear ribonucleoprotein Prp31 | |
| M. musculus | UniProtKB:Q9D6Z1 · MGI:MGI:1914384 (Nol5a · NOP56 · Nop56) | NOP56 ribonucleoprotein homolog (yeast) · 56kDa with KKE/D repeat | |
| M. musculus | UniProtKB:Q6DFW4 · MGI:MGI:1933184 (Nol5 · MSSP · Nop58) | SIK similar protein · NOP58 ribonucleoprotein homolog (yeast) | |
| M. musculus | UniProtKB:Q8CCF0 · MGI:MGI:1916238 (RP11 · PRP31 · Prpf31) | PRP31 pre-mRNA processing factor 31 homolog (yeast) | |
| R. norvegicus | NCBI:XP_218173 · RGD:1305832 (Prpf31) | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) | |
| R. norvegicus | UniProtKB:Q9QZ86 · RGD:620484 (Nol5) | nucleolar protein 5 | |
| R. norvegicus | RGD:1308892 · UniProtKB:Q4KLK7 | ||
| S. cerevisiae | UniProtKB:Q12499 · SGD:S000005837 (NOP5 · NOP58 · YOR310C) | Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis | |
| S. cerevisiae | UniProtKB:P49704 · SGD:S000003323 (YGR091W · PRP31) | Splicing factor, component of the U4/U6-U5 snRNP complex | |
| S. cerevisiae | UniProtKB:Q12460 · SGD:S000004187 (SIK1 · NOP56 · YLR197W) | Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation | |
| S. pombe | UniProtKB:Q9P7S7 · GeneDB_Spombe:SPAC23G3.06 (SPAC23G3.06) | U3 snoRNP protein Nop58 | |
| S. pombe | UniProtKB:O42904 · GeneDB_Spombe:SPBC119.13c (prp31 · SPBC119.13c) | U4/U6 x U5 tri-snRNP complex subunit Prp31 | |
| S. pombe | UniProtKB:O94514 · GeneDB_Spombe:SPBC646.10c (SPBC646.10c) | U3 snoRNP protein Nop56 · U3 snoRNP protein Nop56 (predicted) | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| OMIM (1) | |
|---|---|
| UniProtKB:P49704 · SGD:S000003323 | #600138 RETINITIS PIGMENTOSA 11; RP11 |
| SGD Disease Papers (2) | |
| UniProtKB:P49704 · SGD:S000003323 |  11867543 Makarova OV, et al. (2002) Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing. EMBO J 21(5):1148-57 |
| 11545739 Vithana EN, et al. (2001) A human homolog of yeast pre-mRNA splicing gene, PRP31, underlies autosomal dominant retinitis pigmentosa on chromosome 19q13.4 (RP11). Mol Cell 8(2):375-81 | |