P-POD: Princeton Protein Orthology Database: GO3/Jaccard586

This family has 38 members: 5 Arabidopsis thaliana, 4 Caenorhabditis elegans, 3 Danio rerio, 3 Dictyostelium discoideum, 4 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 4 Homo sapiens, 4 Mus musculus, 4 Rattus norvegicus, 2 Saccharomyces cerevisiae, 3 Schizosaccharomyces pombe.

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GO3/Jaccard586
38 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_187021.2 · TAIR:locus:2079429 (AT3G03710 · F20H23.26 · RIF10)resistant to inhibition with FSM 10⌘
A. thalianaNCBI:NP_190207.1 · TAIR:locus:2075351 (F12M12.180 · AT3G46210)⌘
A. thalianaNCBI:NP_191721.1 · TAIR:locus:2076710 (F15G16.10 · AT3G61620 · RRP41)EXONUCLEASE RRP41⌘
A. thalianaNCBI:NP_196962.1 · TAIR:locus:2222662 (AT5G14580 · T15N1.70 · T15N1_70)⌘
A. thalianaNCBI:NP_194479.2 · TAIR:locus:2124024 (F27G19_90 · AT4G27490 · F27G19.90)⌘
C. elegansWB:WBGene00007201 (exos-4.1 · B0564.1) · UniProtKB:Q17533⌘
C. elegansWB:WBGene00000798 (crn-5 · C14A4.5) · UniProtKB:Q17952⌘
C. elegansWB:WBGene00015266 (BE0003N10.1) · UniProtKB:Q965N3⌘
C. elegansWB:WBGene00000202 (Y6D11A.1 · exos-4.2) · UniProtKB:Q9N4P9⌘
D. rerioUniProtKB:Q6P0I8 · ZFIN:ZDB-GENE-050522-362 (exosc6)exosome component 6⌘
D. rerioUniProtKB:Q1LVM3 · ZFIN:ZDB-GENE-060503-675 (exosc5)exosome component 5⌘
D. rerioUniProtKB:Q6PBZ8 · ZFIN:ZDB-GENE-040426-1702 (exosc4)exosome component 4⌘
D. discoideumUniProtKB:Q54EU6 · dictyBase:DDB_G0291328 (DDB_G0291328)Exosome complex exonuclease rrp41, putative.⌘
D. discoideumdictyBase:DDB_G0284053 (DDB_G0284053) · UniProtKB:Q54Q83⌘
D. discoideumdictyBase:DDB_G0271396 (DDB_G0271396) · UniProtKB:Q55BB0⌘
D. melanogasterFB:FBgn0032487 (Ski6 · dRrp41 · CG15481 · dSki6) · UniProtKB:Q8SYC8⌘
D. melanogasterFB:FBgn0037815 (dRrp46 · CG4043 · Rrp46) · UniProtKB:Q95TW1⌘
D. melanogasterFB:FBgn0039846 (CG11337) · UniProtKB:Q9V9X7⌘
D. melanogasterFB:FBgn0036916 (dMtr3 · CG8025 · Mtr3) · UniProtKB:Q9VW53⌘
E. coliUniProtKB:P05055 · ECOLI:EG10743-MONOMER (ECK3152 · b3164 · Pnp · pnp · bfl)polynucleotide phosphorylase monomer⌘
G. gallusNCBI:XP_419282 · ENTREZ:421206
H. sapiensENSEMBL:ENSG00000178896 · UniProtKB:Q9NPD3 (Q9NPD3 · EXOS4_HUMAN · SKI6 · IPI00745613 · EXOSC4 · RRP41)Exosome complex exonuclease RRP41⌘
H. sapiensENSEMBL:ENSG00000077348 · UniProtKB:Q9NQT4 (IPI00015955 · RRP46 · CML28 · EXOSC5 · EXOS5_HUMAN · Q9NQT4)Exosome complex exonuclease RRP46⌘
H. sapiensENSEMBL:ENSG00000157344 · UniProtKB:Q5RKV6 (EXOS6_HUMAN · Q5RKV6 · EXOSC6 · IPI00073602 · MTR3)Exosome complex exonuclease MTR3⌘
H. sapiensENSEMBL:ENSG00000138035 · UniProtKB:Q8TCS8 (IPI00744711 · PNPT1 · PNPASE · PNPT1_HUMAN · Q8TCS8)Polyribonucleotide nucleotidyltransferase 1, mitochondrial⌘
M. musculusNCBI:NP_082145 · MGI:MGI:1918951 (PNPase · Pnpt1)polynucleotide phosphorylase · polyribonucleotide nucleotidyltransferase 1⌘
M. musculusUniProtKB:Q921I9 · MGI:MGI:1923576 (Exosc4)exosome component 4⌘
M. musculusUniProtKB:Q9CRA8 · MGI:MGI:107889 (D7Wsu180e · Exosc5)exosome component 5⌘
M. musculusUniProtKB:Q8BTW3 · MGI:MGI:1919794 (Mtr3 · Exosc6)exosome component 6⌘
R. norvegicusNCBI:XP_001077520 · RGD:1309832 (Exosc6)exosome component 6⌘
R. norvegicusNCBI:XP_218343 · RGD:1307861 (Exosc5)exosome component 5⌘
R. norvegicusNCBI:XP_216949 · RGD:1310986 (Exosc4)exosome component 4⌘
R. norvegicusUniProtKB:Q562B9 · RGD:1307987 (Pnpt1)polyribonucleotide nucleotidyltransferase 1⌘
S. cerevisiaeUniProtKB:P46948 · SGD:S000003427 (ECM20 · SKI6 · YGR195W · RRP41)Exosome non-catalytic core component⌘
S. cerevisiaeUniProtKB:P53256 · SGD:S000003327 (RRP46 · YGR095C)Exosome non-catalytic core component⌘
S. pombeUniProtKB:O42872 · GeneDB_Spombe:SPAC3G9.10c (ski6 · SPAC3G9.10c)exosomal 3'-to-5' phosphorolytic exoribonuclease Ski6⌘
S. pombeUniProtKB:O42894 · GeneDB_Spombe:SPBC115.01c (rrp46 · SPBC115.01c)exosome subunit Rrp46⌘
S. pombeUniProtKB:Q9P7R3 · GeneDB_Spombe:SPBC211.08c (SPBC211.08c)exosomal 3'-5' exoribonuclease, PH-like⌘
ProteinPublicationCurator Notes
UniProtKB:P46948 · SGD:S000003427PMID:10930416 Chekanova JA, et al. Poly(A) tail-dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome-sized complex in plant and yeast cells. J Biol Chem. 2000 Oct 20;275(42):33158-66.The A. thaliana protein AT3G61620.1 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
SGD Disease Papers (1)
UniProtKB:P53256 · SGD:S000003327PMID:10465791 Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58
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