P-POD: Princeton Protein Orthology Database: GO3/Jaccard40

This family has 295 members: 70 Arabidopsis thaliana, 28 Caenorhabditis elegans, 42 Danio rerio, 21 Dictyostelium discoideum, 15 Drosophila melanogaster, 26 Gallus gallus, 26 Homo sapiens, 26 Mus musculus, 27 Rattus norvegicus, 7 Saccharomyces cerevisiae, 7 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Jaccard40
295 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_568174.1 · TAIR:locus:2170234 (AT5G06750 · MPH15_11 · MPH15.11)⌘
A. thalianaNCBI:NP_566949.2 · TAIR:locus:2081770 (AT3G51370 · F26O13.10)⌘
A. thalianaNCBI:NP_191065.2 · TAIR:locus:2097238 (AT3G55050 · T15C9.50)⌘
A. thalianaNCBI:NP_194914.1 · TAIR:locus:2116777 (F11C18.60 · AT4G31860 · F11C18_60)⌘
A. thalianaNCBI:NP_195118.1 · TAIR:locus:2118899 (F17I5_110 · F17I5.110 · AT4G33920)⌘
A. thalianaNCBI:NP_001031819.1 · TAIR:locus:2149775 (F7A7.220 · F7A7_220 · AT5G01700)⌘
A. thalianaNCBI:NP_175238.2 · TAIR:locus:2023812 (AT1G48040 · T2J15.5)⌘
A. thalianaNCBI:NP_851086.1 · TAIR:locus:2143325 (F15F15.3 · AT5G27930)⌘
A. thalianaNCBI:NP_176948.2 · TAIR:locus:2008545 (F12A21_5 · F12A21.5 · AT1G67820)⌘
A. thalianaNCBI:NP_564504.1 · TAIR:locus:2203766 (T3F24.2 · T3F24_2 · AT1G47380)⌘
A. thalianaNCBI:NP_565553.1 · TAIR:locus:2046738 (XLG1 · F26B6_11 · F26B6.11 · AT2G23460 · ATXLG1)EXTRA-LARGE G-PROTEIN 1⌘
A. thalianaNCBI:NP_199989.1 · TAIR:locus:2165371 (MIO24.11 · AHG1 · AT5G51760 · MIO24_11)ABA-hypersensitive germination 1⌘
A. thalianaNCBI:NP_568786.1 · TAIR:locus:2163781 (MFH8.8 · MFH8_8 · AT5G53140)⌘
A. thalianaNCBI:NP_680572.1 · TAIR:locus:504955459 (AT4G03415)⌘
A. thalianaNCBI:NP_565172.1 · TAIR:locus:2194734 (T11I11.14 · T11I11_14 · AT1G78200)⌘
A. thalianaNCBI:NP_187215.1 · TAIR:locus:2078117 (F18C1.9 · AT3G05640 · F18C1_9)⌘
A. thalianaNCBI:NP_192566.1 · TAIR:locus:2132497 (T12G13_100 · T12G13.100 · AT4G08260)⌘
A. thalianaNCBI:NP_566554.1 · TAIR:locus:2089293 (AT3G16560 · MDC8.3)⌘
A. thalianaNCBI:NP_568237.1 · TAIR:locus:2183695 (MAJ23.3 · AT5G10740)⌘
A. thalianaNCBI:NP_174731.1 · TAIR:locus:2008341 (F11O6.14 · AT1G34750)⌘
A. thalianaNCBI:NP_180079.1 · TAIR:locus:2047344 (F13D4.1 · AT2G25070)⌘
A. thalianaNCBI:NP_180563.1 · TAIR:locus:2045678 (F23F1.6 · AP2C1 · AT2G30020 · F23F1_6)⌘
A. thalianaNCBI:NP_173072.1 · TAIR:locus:2032880 (F3O9_3 · AT1G16220 · F3O9.3)⌘
A. thalianaNCBI:NP_175057.2 · TAIR:locus:2029172 (F9C16_6 · F9C16.6 · AT1G43900)⌘
A. thalianaNCBI:NP_200515.1 · TAIR:locus:2164610 (MHM17_19 · AT5G57050 · ABI2 · MHM17.19)ABA INSENSITIVE 2 · PROTEIN PHOSPHATASE 2C⌘
A. thalianaNCBI:NP_001030625.1 · TAIR:locus:2075487 (F13E7.31 · F13E7_31 · AT3G02750)⌘
A. thalianaNCBI:NP_201409.1 · TAIR:locus:2156877 (AT5G66080 · K2A18_16 · K2A18.16)⌘
A. thalianaNCBI:NP_190715.1 · TAIR:locus:2081785 (AT3G51470 · F26O13.110)⌘
A. thalianaNCBI:NP_564045.1 · TAIR:locus:2194035 (T10F20.4 · AT1G18030 · T10F20_4)⌘
A. thalianaNCBI:NP_172196.1 · TAIR:locus:2007327 (AT1G07160 · F10K1_13 · F10K1.13)⌘
A. thalianaNCBI:NP_200730.1 · TAIR:locus:2168449 (AT5G59220 · MNC17.13 · MNC17_13)⌘
A. thalianaNCBI:NP_181021.1 · TAIR:locus:2061579 (T29F13.5 · AT2G34740 · T29F13_5)⌘
A. thalianaNCBI:NP_567145.1 · TAIR:locus:2077329 (AT3G63340 · MAA21.3)⌘
A. thalianaNCBI:NP_181547.1 · TAIR:locus:2065046 (AT2G40180 · T7M7.17 · ATHPP2C5)⌘
A. thalianaNCBI:NP_191891.1 · TAIR:locus:2077319 (AT3G63320 · MAA21.1)⌘
A. thalianaTAIR:locus:2183612 (T30G6_11 · T30G6.11 · AT5G36250) · NCBI:NP_198474.1⌘
A. thalianaNCBI:NP_177421.1 · TAIR:locus:2030230 (F28P22_4 · F28P22.4 · HAB1 · AT1G72770)HOMOLOGY TO ABI1⌘
A. thalianaNCBI:NP_197876.1 · TAIR:locus:2149363 (F6A4_150 · F6A4.150 · AT5G24940)⌘
A. thalianaNCBI:NP_195021.1 · TAIR:locus:2123792 (AT4G32950 · F26P21_70 · F26P21.70)⌘
A. thalianaNCBI:NP_180499.1 · TAIR:locus:2043142 (AT2G29380 · F16P2_24 · F16P2.24)⌘
A. thalianaNCBI:NP_178081.2 · TAIR:locus:2019868 (F20B17.6 · F20B17_6 · AT1G79630)⌘
A. thalianaNCBI:NP_173199.2 · TAIR:locus:2007943 (F1L3.38 · AT1G17550 · HAB2)⌘
A. thalianaNCBI:NP_177008.1 · TAIR:locus:2202339 (T2E12.9 · AT1G68410 · T2E12_9)⌘
A. thalianaNCBI:NP_194509.1 · TAIR:locus:2137400 (T27E11_40 · T27E11.40 · AT4G27800)⌘
A. thalianaNCBI:NP_194338.1 · TAIR:locus:2005488 (ABI1 · F20B18_190 · F20B18.190 · AT4G26080)ABA INSENSITIVE 1 · PROTEIN PHOSPHATASE 2C ABI1⌘
A. thalianaNCBI:NP_187868.2 · TAIR:locus:2091265 (T2E22.7 · AT3G12620)⌘
A. thalianaNCBI:NP_197429.1 · TAIR:locus:2150220 (RAG1 · AT5G19280 · KAPP · T24G5.3)ROOT ALTERNATED GROWTH 1 · KINASE ASSOCIATED PROTEIN PHOSPHATASE⌘
A. thalianaNCBI:NP_850737.1 · TAIR:locus:2098018 (AT3G62260 · T17J13.220)⌘
A. thalianaNCBI:NP_189350.2 · TAIR:locus:2095133 (MYF5.1 · AT3G27140)⌘
A. thalianaNCBI:NP_195564.2 · TAIR:locus:2121234 (F20M13_80 · F20M13.80 · AT4G38520)⌘
A. thalianaNCBI:NP_187748.1 · TAIR:locus:2080787 (PP2CA · ATPP2CA · AT3G11410 · F24K9.8 · AHG3)ARABIDOPSIS THALIANA PROTEIN PHOSPHATASE 2CA⌘
A. thalianaNCBI:NP_180926.1 · TAIR:locus:2057635 (T1B8_2 · T1B8.2 · AT2G33700)⌘
A. thalianaNCBI:NP_194903.2 · TAIR:locus:2124784 (WIN2 · F28M20_60 · AT4G31750 · F28M20.60)HOPW1-1-INTERACTING 2⌘
A. thalianaNCBI:NP_195896.2 · TAIR:locus:2151256 (F9G14_70 · AT5G02760 · F9G14.70)⌘
A. thalianaNCBI:NP_180133.1 · TAIR:locus:2050296 (AT2G25620 · F3N11_7 · F3N11.7)⌘
A. thalianaNCBI:NP_567808.1 · TAIR:locus:2121373 (F20O9.80 · AT4G28400 · F20O9_80)⌘
A. thalianaNCBI:NP_564165.1 · TAIR:locus:2196531 (T16E15.10 · AT1G22280 · T16E15_10)⌘
A. thalianaNCBI:NP_172223.1 · TAIR:locus:2025087 (F22G5_22 · F22G5.22 · AT1G07430)⌘
A. thalianaNCBI:NP_566566.1 · TAIR:locus:2086097 (AT3G17090 · K14A17.4)⌘
A. thalianaNCBI:NP_973490.1 · TAIR:locus:2046046 (AT2G20630 · F23N11_5 · F23N11.5)⌘
A. thalianaNCBI:NP_180198.1 · TAIR:locus:2005529 (t1d16.6 · AT2G26300 · ATGPA1 · t1d16_6 · GPA1)GP ALPHA 1 · ARABIDOPSIS THALIANA G PROTEIN ALPHA SUBUNIT 1 · G PROTEIN ALPHA SUBUNIT · G PROTEIN ALPHA SUBUNIT 1⌘
A. thalianaNCBI:NP_188351.2 · TAIR:locus:2089035 (MGD8.13 · AT3G17250)⌘
A. thalianaNCBI:NP_188303.1 · TAIR:locus:2086755 (K20I9.2 · AT3G16800)⌘
A. thalianaNCBI:NP_187278.2 · TAIR:locus:2082465 (AT3G06270 · F28L1.21 · F28L1_21)⌘
A. thalianaNCBI:NP_188144.1 · TAIR:locus:2087095 (AT3G15260 · K7L4.6)⌘
A. thalianaNCBI:NP_171856.1 · TAIR:locus:2020863 (F21B7.20 · AT1G03590)⌘
A. thalianaNCBI:NP_197973.2 · TAIR:locus:2180612 (AT5G26010 · T1N24.8 · T1N24_8)⌘
A. thalianaNCBI:NP_195165.2 · TAIR:locus:2116204 (F10M10.160 · AT4G34390 · F10M10_160 · XLG2)extra-large GTP-binding protein 2⌘
A. thalianaNCBI:NP_849621.1 · TAIR:locus:2195331 (T12M4_15 · T12M4.15 · AT1G09160)⌘
A. thalianaNCBI:NP_174475.1 · TAIR:locus:2034446 (XLG3 · AT1G31930 · F5M6_7 · F5M6.7)extra-large GTP-binding protein 3⌘
C. elegansWB:WBGene00001412 (T19C3.8 · fem-2) · UniProtKB:P49594 (T19C3.8 · FEM2_CAEEL · fem-2)Ca(2+)/calmodulin-dependent protein kinase phosphatase⌘⌘
C. elegansWB:WBGene00001648 (C26C6.2 · goa-1) · UniProtKB:P51875 (GNAO_CAEEL · C26C6.2 · goa-1)Guanine nucleotide-binding protein G(o) subunit alpha⌘⌘
C. elegansWB:WBGene00001672 (gpa-10 · C55H1.2) · UniProtKB:Q9BIG4⌘
C. elegansWB:WBGene00001673 (gpa-11 · C16A11.1) · UniProtKB:O76584⌘
C. elegansWB:WBGene00001674 (gpa-12 · F18G5.3) · UniProtKB:Q19572⌘
C. elegansWB:WBGene00001675 (gpa-13 · F18E2.5) · UniProtKB:Q9XTB2⌘
C. elegansWB:WBGene00001676 (B0207.3 · gpa-14) · UniProtKB:Q9BIG2⌘
C. elegansWB:WBGene00001677 (M04C7.1 · gpa-15) · UniProtKB:P91907⌘
C. elegansWB:WBGene00001678 (gpa-16 · Y95B8A.5) · UniProtKB:Q9N2V6 (GPA16_CAEEL · gpa-16 · spn-1 · Y95B8A.5)Guanine nucleotide-binding protein alpha-16 subunit⌘⌘
C. elegansWB:WBGene00003850 (odr-3 · C34D1.3) · UniProtKB:Q18434⌘
C. elegansWB:WBGene00001663 (T19C4.6 · gpa-1) · UniProtKB:P28051⌘
C. elegansWB:WBGene00001664 (F38E1.5 · gpa-2) · UniProtKB:P22454⌘
C. elegansWB:WBGene00001665 (gpa-3 · E02C12.5) · UniProtKB:P28052⌘
C. elegansWB:WBGene00001666 (gpa-4 · T07A9.7) · UniProtKB:Q9BIG5⌘
C. elegansWB:WBGene00001667 (gpa-5 · F53B1.7) · UniProtKB:Q20701⌘
C. elegansWB:WBGene00001668 (F48C11.1 · gpa-6) · UniProtKB:Q93743⌘
C. elegansWB:WBGene00001669 (gpa-7 · R10H10.5) · UniProtKB:Q21917⌘
C. elegansWB:WBGene00001670 (gpa-8 · F56H9.3) · UniProtKB:Q20907⌘
C. elegansWB:WBGene00001671 (F56H9.4 · gpa-9) · UniProtKB:Q20910⌘
C. elegansWB:WBGene00018362 (F42G9.1) · UniProtKB:P49595⌘
C. elegansWB:WBGene00011953 (T23F11.1) · UniProtKB:P49596⌘
C. elegansWB:WBGene00020997 (gpa-18 · W03F8.9) · UniProtKB:A1IMC0⌘
C. elegansWB:WBGene00001745 (gsa-1 · R06A10.2) · UniProtKB:O18678⌘
C. elegansWB:WBGene00009354 (F33A8.6) · UniProtKB:O62212⌘
C. elegansWB:WBGene00001196 (M01D7.7 · egl-30) · UniProtKB:Q17386⌘
C. elegansWB:WBGene00006460 (F25D1.1 · tag-93) · UniProtKB:Q19775⌘
C. elegansWB:WBGene00021856 (Y54F10BM.1 · fbxa-1) · UniProtKB:Q95XK4⌘
C. elegansWB:WBGene00022196 (Y71H2B.7 · gpa-17) · UniProtKB:Q9N4F4⌘
D. rerioENSEMBL:ENSDARP00000063142
D. rerioENSEMBL:ENSDARP00000073634
D. rerioENSEMBL:ENSDARP00000096346
D. rerioENSEMBL:ENSDARP00000065332
D. rerioENSEMBL:ENSDARP00000091638
D. rerioENSEMBL:ENSDARP00000074076
D. rerioENSEMBL:ENSDARP00000054786
D. rerioENSEMBL:ENSDARP00000047527
D. rerioENSEMBL:ENSDARP00000028232
D. rerioENSEMBL:ENSDARP00000063258
D. rerioENSEMBL:ENSDARP00000020119
D. rerioZFIN:ZDB-GENE-061103-118 (zgc:154091) · UniProtKB:A0JMP2⌘
D. rerioZFIN:ZDB-GENE-070410-122 (zgc:162985) · UniProtKB:A3KP70⌘
D. rerioZFIN:ZDB-GENE-060929-136 (zgc:153235) · UniProtKB:Q08CD7⌘
D. rerioUniProtKB:Q1LW06 · ZFIN:ZDB-GENE-050208-597 (gna11)guanine nucleotide binding protein (G protein), alpha 11 (Gq class)⌘
D. rerioZFIN:ZDB-GENE-050208-781 (si:ch211-207c7.1) · UniProtKB:Q1LW07⌘
D. rerioZFIN:ZDB-GENE-050208-540 (si:ch211-207c7.2) · UniProtKB:Q1LW08⌘
D. rerioZFIN:ZDB-GENE-050208-700 (si:ch211-207c7.3) · UniProtKB:Q1LW09⌘
D. rerioUniProtKB:Q53VM5 · ZFIN:ZDB-GENE-070326-2 (ppm1e)protein phosphatase 1E (PP2C domain containing)⌘
D. rerioUniProtKB:Q5CZQ7 · ZFIN:ZDB-GENE-050306-8 (ppm1k)protein phosphatase 1K (PP2C domain containing)⌘
D. rerioZFIN:ZDB-GENE-041121-9 (zgc:101761) · UniProtKB:Q5RKP9⌘
D. rerioENSEMBL:ENSDARG00000043250 · UniProtKB:Q5TZI2
D. rerioUniProtKB:Q5U386 · ZFIN:ZDB-GENE-041114-185 (ppm1a)protein phosphatase 1A, magnesium dependent, alpha isoform⌘
D. rerioUniProtKB:Q5U3H6 · ZFIN:ZDB-GENE-041114-26 (gnal)guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type⌘
D. rerioUniProtKB:Q5YKG2 · ZFIN:ZDB-GENE-030131-8277 (gna13b)guanine nucleotide binding protein (G protein), alpha 13b⌘
D. rerioUniProtKB:Q5YKG4 · ZFIN:ZDB-GENE-050221-1 (gna12)guanine nucleotide binding protein (G protein) alpha 12⌘
D. rerioUniProtKB:Q68FN4 · ZFIN:ZDB-GENE-991102-16 (pp2cb)protein phosphatase type 2C beta⌘
D. rerioUniProtKB:Q6AZW4 · ZFIN:ZDB-GENE-040808-7 (gna14)guanine nucleotide binding protein (G protein), alpha 14⌘
D. rerioZFIN:ZDB-GENE-040801-146 (zgc:100942) · UniProtKB:Q6DEH5⌘
D. rerioZFIN:ZDB-GENE-040426-2731 (zgc:73371) · UniProtKB:Q6NY18⌘
D. rerioUniProtKB:Q6NYP6 · ZFIN:ZDB-GENE-991102-15 (pp2ca2)protein phosphatase type 2C alpha 2⌘
D. rerioUniProtKB:Q6P967 · ZFIN:ZDB-GENE-040426-1693 (gnao1b)guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b⌘
D. rerioUniProtKB:Q6PBP1 · ZFIN:ZDB-GENE-040426-1757 (gnao1a)guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a⌘
D. rerioUniProtKB:Q6TNT8 · ZFIN:ZDB-GENE-030131-8365 (gnai2l)guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like⌘
D. rerioUniProtKB:Q7T3D3 · ZFIN:ZDB-GENE-040426-1310 (gnai1)guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1⌘
D. rerioUniProtKB:Q7ZVN8 · ZFIN:ZDB-GENE-040426-815 (ppm1d)protein phosphatase 1D magnesium-dependent, delta isoform⌘
D. rerioUniProtKB:Q7ZW82 · ZFIN:ZDB-GENE-030131-2229 (gnaia)guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a⌘
D. rerioUniProtKB:Q7ZWI5 · ZFIN:ZDB-GENE-030131-5861 (gnai2)guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2⌘
D. rerioUniProtKB:Q90WX5 · ZFIN:ZDB-GENE-011128-10 (gnat2)guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2⌘
D. rerioUniProtKB:Q90WX6 · ZFIN:ZDB-GENE-011128-11 (gnat1)guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1⌘
D. rerioUniProtKB:Q53VM6 · ZFIN:ZDB-GENE-051128-2 (ppm1f)protein phosphatase 1F (PP2C domain containing)⌘
D. rerioZFIN:ZDB-GENE-041114-27 (zgc:103518) · UniProtKB:Q5U3H7⌘
D. discoideumNCBI:EAL65447.2 · dictyBase:DDB_G0283919 (DDB_G0283919)protein phosphatase 2C-related protein⌘
D. discoideumUniProtKB:Q55EP5 · dictyBase:DDB_G0268802 (gpa10 · Ga10 · gpaJ · Galpha10)G-protein subunit alpha 10⌘
D. discoideumUniProtKB:Q8T130 · dictyBase:DDB_G0276343 (gpaK · gpa11 · Galpha11 · Ga11)G-protein subunit alpha 11⌘
D. discoideumUniProtKB:Q54VG1 · dictyBase:DDB_G0280351 (Ga12 · Galpha12 · gpa12 · gpaL)G-protein subunit alpha 12⌘
D. discoideumUniProtKB:P16894 · dictyBase:DDB_G0283349 (gpa1 · Ga1 · gpaA · Galpha1)G-protein subunit alpha 1⌘
D. discoideumUniProtKB:P16051 · dictyBase:DDB_G0276267 (Galpha2 · gpaB · gpa2 · Ga2)G-protein subunit alpha 2⌘
D. discoideumUniProtKB:Q54KV6 · dictyBase:DDB_G0287031 (gpa3 · Ga3 · Galpha3 · gpaC)G-protein subunit alpha 3⌘
D. discoideumUniProtKB:P34042 · dictyBase:DDB_G0285425 (Ga4 · gpaD · gpa4 · Galpha4)G-protein subunit alpha 4⌘
D. discoideumUniProtKB:P34043 · dictyBase:DDB_G0286185 (gpaE · Galpha5 · gpa5 · Ga5)G-protein subunit alpha 5⌘
D. discoideumUniProtKB:P34044 · dictyBase:DDB_G0283151 (gpa6 · Ga6 · Galpha6 · gpaF)G-protein subunit alpha 6⌘
D. discoideumUniProtKB:P34045 · dictyBase:DDB_G0276455 (gpa7 · gpaG · Ga7 · Galpha7)G-protein subunit alpha 7⌘
D. discoideumUniProtKB:P34046 · dictyBase:DDB_G0284469 (Ga8 · gpaH · gpa8 · Galpha8)G-protein subunit alpha 8⌘
D. discoideumUniProtKB:Q54R41 · dictyBase:DDB_G0283419 (Galpha9 · gpaI · Ga9 · gpa9)G-protein subunit alpha 9⌘
D. discoideumUniProtKB:O15743 · dictyBase:DDB_G0276155 (spnA · Spn · Spalten)protein serine/threonine phosphatase⌘
D. discoideumUniProtKB:Q54GL8 · dictyBase:DDB_G0290075 (PP2C · DDB_G0290075)protein phosphatase 2C⌘
D. discoideumUniProtKB:Q54PX6 · dictyBase:DDB_G0284243 (DDB_G0284243)protein phosphatase 2C-related protein⌘
D. discoideumUniProtKB:Q54T01 · dictyBase:DDB_G0282105 (PP2C · DDB_G0282105)protein phosphatase 2C⌘
D. discoideumUniProtKB:Q54WS9 · dictyBase:DDB_G0279461 (DDB_G0279461 · PP2C)protein phosphatase 2C⌘
D. discoideumUniProtKB:Q54Y00 · dictyBase:DDB_G0278499 (PP2C · DDB_G0278499)protein phosphatase 2C⌘
D. discoideumUniProtKB:Q55C81 · dictyBase:DDB_G0270176 (PP2C · DDB_G0270176)protein phosphatase 2C, leucine-rich repeat-containing protein (LRR)⌘
D. discoideumUniProtKB:Q86A16 · dictyBase:DDB_G0272680 (DDB_G0272680 · PP2C)protein phosphatase 2C⌘
D. melanogasterUniProtKB:Q05337 · FB:FBgn0010223 (Gfalpha · Gf · CG12232 · Galpha73B)GTP-binding protein alpha-subunit · G protein alpha 73B · Gf alpha⌘
D. melanogasterUniProtKB:P20353 · FB:FBgn0001104 (G[[alphai]] · Galpha65A · DG[[alpha1]] · G-ialpha65A · G[[i]]alpha · Gi · Galpha[[i]] · CG10060 · G-oalpha65A · Galphai · Gialpha · i · G-alpha-65A · Gi-alpha · Galphaiota65A · DGalpha1 · G-ia65A · Galpha[[i65A]] · Gai)G protein I a-subunit 65A · G protein alpha-subunit · G protein alphai subunit 65A · Galpha i · G protein alpha subunit · G protein alpha o subunit 65A · G protein alphao subunit 65A⌘
D. melanogasterFB:FBgn0000384 (CG17678 · mat(2)cta · conc · Concertina · CG40010 · cta · Cta · concertina · mat(2)fog) · UniProtKB:P25157⌘
D. melanogasterUniProtKB:P16378 · FB:FBgn0001122 (G[[o]]alpha · Bkh · dgoalpha · G-oalpha · Goa · Go · Galphao47A · G-alpha-47A · Galpha[[0]] · Galpha47A · Galphao · DG[[o]] · Go-alpha · n · dgo · Galpha[[047A]] · DROGPAD · Drogpad · brokenhearted · CG2204 · bkh · Goalpha · DGalpha0 · G[[oalpha]] · brokenheart · G(o)alpha47A · DGalpha[[o]] · G-oalpha47A · alpha(o) · Galpha[[o]])G protein oalpha 47A⌘
D. melanogasterUniProtKB:P23625 · FB:FBgn0004435 (DGq · Gqalpha{e} · Galpha49b · G[[alphaq]] · Galpha · dgq · dG[[alphaq]] · Dgq · dGqa-49b · G[q] · dGqalpha-49b · DGqalpha · G[[q]] · dGaalpha · G?q · G[[q]]alpha · Dromel_CG17759_galpha49b_uORF · Gqalpha[[e]] · Gqalpha · Gq · G[[qalpha]] · DGalpha[[q]] · CG17759 · G-protein-alpha[[q]] · Gqa-3 · G[[a]]q · dgqalpha · Galphaq · DGalphaq · Galpha[[q]] · dG[[q]]alpha · Dromel_CG17759_galpha49b_mORF · Galpha49B · dGqalpha-3 · dGqalpha · DmGalpha[[q]] · Gaq)G alpha 49B · G protein 49B · G protein alpha49B⌘
D. melanogasterUniProtKB:P20354 · FB:FBgn0001123 (Gsalpha60A · Gs-alpha60A · Galphas · DGs · Galpha60A · dgs · dgsalpha · Gs · GalphaS · G[[alphas]] · G[[s]]alpha · Galpha[[s]] · GSalpha · G[[S]]alpha · CG2835 · Gsalpha · G-alpha-60A · G-salpha60A · dG[[alphas]])stimulatory alpha subunit of G protein · G protein salpha 60A · G-alpha s⌘
D. melanogasterUniProtKB:O77023 · FB:FBgn0022768 (anon-WO03040301.132 · PP2C · Pp2C1 · PP2C1 · dpp2c1 · CG2984)Protein phosphatase 2C⌘
D. melanogasterFB:FBgn0033021 (CG10417 · PP2Cg) · UniProtKB:Q7K4Q5⌘
D. melanogasterFB:FBgn0058005 (CG40005) · UniProtKB:Q7PL78⌘
D. melanogasterFB:FBgn0033756 (BcDNA:SD21019 · CG17760) · UniProtKB:Q8MQV5⌘
D. melanogasterFB:FBgn0086361 (PP2Cb · pp2c99B · SK3-1 · alph · CG1906 · alphabet) · UniProtKB:Q961C5⌘
D. melanogasterFB:FBgn0039421 (PP2Cb · CG6036) · UniProtKB:Q9VBF9⌘
D. melanogasterFB:FBgn0032702 (CG10376 · PP2C) · UniProtKB:Q9VJ61⌘
D. melanogasterFB:FBgn0035425 (PP2C · CG17746) · UniProtKB:Q9VZS1⌘
D. melanogasterFB:FBgn0035143 (PP2C · CG12169 · dPPM1 · Ppm1) · UniProtKB:Q9W0Q0⌘
G. gallusNCBI:NP_001008746 · ENTREZ:474379
G. gallusNCBI:XP_415067 · ENTREZ:416772
G. gallusNCBI:XP_428163 · ENTREZ:430608
G. gallusNCBI:XP_429163 · ENTREZ:431611
G. gallusNCBI:XP_001232703 · ENTREZ:415698
G. gallusNCBI:XP_001233237 · ENTREZ:769924
G. gallusNCBI:XP_422661 · ENTREZ:424850
G. gallusNCBI:XP_425425 · ENTREZ:427851
G. gallusNCBI:XP_426717 · ENTREZ:429162
G. gallusNCBI:XP_420574 · ENTREZ:422614
G. gallusNCBI:XP_415686 · ENTREZ:417434
G. gallusNCBI:XP_415871 · ENTREZ:417627
G. gallusNCBI:XP_001236292 · ENTREZ:776792
G. gallusNCBI:XP_001236777 · ENTREZ:777312
G. gallusNCBI:XP_421422 · ENTREZ:423525
G. gallusNCBI:XP_001232445 · ENTREZ:770226
G. gallusNCBI:XP_001231542 · ENTREZ:419313
G. gallusNCBI:XP_001233625 · ENTREZ:770290
G. gallusENTREZ:396368 · UniProtKB:P50146 (P50146 · GNAI1_CHICK · IPI00585976 · GNAI1)Guanine nucleotide-binding protein G(i), alpha-1 subunit⌘
G. gallusENTREZ:396367 · UniProtKB:P50147 (IPI00589157 · GNAI2 · P50147 · GNAI2_CHICK)Guanine nucleotide-binding protein G(i), alpha-2 subunit⌘
G. gallusUniProtKB:Q5F397 (RCJMB04_26p17 · Q5F397 · IPI00680714) · ENTREZ:421404⌘
G. gallusUniProtKB:Q5F3B5 (IPI00585601 · RCJMB04_23b22 · Q5F3B5) · ENTREZ:427262⌘
G. gallusUniProtKB:Q71RI7 (IPI00577333 · Q71RI7) · ENTREZ:374077⌘
G. gallusENTREZ:374097 · UniProtKB:Q90846 (Q90846 · IPI00570876)Galpa i3-o⌘
G. gallusUniProtKB:Q9DG27 (Q9DG27 · IPI00577038) · ENTREZ:395425⌘
G. gallusUniProtKB:Q9DG28 (Q9DG28 · IPI00594296) · ENTREZ:395426⌘
H. sapiensENSEMBL:ENSG00000088256 · UniProtKB:P29992 (P29992 · GA11 · IPI00305551 · GNA11 · GNA11_HUMAN)Guanine nucleotide-binding protein subunit alpha-11⌘
H. sapiensENSEMBL:ENSG00000146535 · UniProtKB:Q03113 (IPI00328744 · GNA12_HUMAN · Q03113 · GNA12)Guanine nucleotide-binding protein subunit alpha-12⌘
H. sapiensENSEMBL:ENSG00000120063 · UniProtKB:Q14344 (Q14344 · GNA13_HUMAN · IPI00290928 · GNA13)Guanine nucleotide-binding protein subunit alpha-13⌘
H. sapiensENSEMBL:ENSG00000156049 · UniProtKB:O95837 (GNA14_HUMAN · GNA14 · IPI00000695 · O95837)Guanine nucleotide-binding protein subunit alpha-14⌘
H. sapiensENSEMBL:ENSG00000060558 · UniProtKB:P30679 (GNA16 · GNA15 · IPI00027243 · P30679 · GNA15_HUMAN)Guanine nucleotide-binding protein subunit alpha-15⌘
H. sapiensENSEMBL:ENSG00000127955 · UniProtKB:P63096 (P63096 · GNAI1_HUMAN · GNAI1 · IPI00337415)Guanine nucleotide-binding protein G(i), alpha-1 subunit⌘
H. sapiensENSEMBL:ENSG00000114353 · UniProtKB:P04899 (GNAI2B · GNAI2_HUMAN · GNAI2 · P04899 · IPI00217906 · IPI00748145)Guanine nucleotide-binding protein G(i), alpha-2 subunit⌘
H. sapiensENSEMBL:ENSG00000065135 · UniProtKB:P08754 (P08754 · IPI00220578 · GNAI3_HUMAN · GNAI3)Guanine nucleotide-binding protein G(k) subunit alpha⌘
H. sapiensENSEMBL:ENSG00000141404 · UniProtKB:P38405 (IPI00006395 · GNAL · P38405 · GNAL_HUMAN)Guanine nucleotide-binding protein G(olf) subunit alpha⌘
H. sapiensENSEMBL:ENSG00000087258 · UniProtKB:P09471 (IPI00220281 · P09471 · GNAO_HUMAN · GNAO1 · IPI00398700)Guanine nucleotide-binding protein G(o) subunit alpha⌘
H. sapiensENSEMBL:ENSG00000156052 · UniProtKB:P50148 (GAQ · P50148 · GNAQ · GNAQ_HUMAN · IPI00288947)Guanine nucleotide-binding protein G(q) subunit alpha⌘
H. sapiensENSEMBL:ENSG00000087460 · UniProtKB:Q5JWF2 (GNAS1 · GNAS1_HUMAN · IPI00154366 · Q5JWF2 · IPI00095891 · GNAS · IPI00646491)Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas⌘
H. sapiensENSEMBL:ENSG00000114349 · UniProtKB:P11488 (IPI00218488 · GNAT1 · GNAT1_HUMAN · GNATR · P11488)Guanine nucleotide-binding protein G(t) subunit alpha-1⌘
H. sapiensENSEMBL:ENSG00000134183 · UniProtKB:P19087 (P19087 · GNATC · IPI00217269 · GNAT2 · GNAT2_HUMAN)Guanine nucleotide-binding protein G(t) subunit alpha-2⌘
H. sapiensENSEMBL:ENSG00000214415 · UniProtKB:A8MTJ3 (GNAT3_HUMAN · IPI00248911 · A8MTJ3 · GNAT3)Guanine nucleotide-binding protein G(t) subunit alpha-3⌘
H. sapiensENSEMBL:ENSG00000128266 · UniProtKB:P19086 (IPI00328128 · GNAZ_HUMAN · P19086 · GNAZ)Guanine nucleotide-binding protein G(z) subunit alpha⌘
H. sapiensENSEMBL:ENSG00000132323 · UniProtKB:Q9H0C8 (ILKAP_HUMAN · Q9H0C8 · IPI00006164 · ILKAP)Integrin-linked kinase-associated serine/threonine phosphatase 2C⌘
H. sapiensENSEMBL:ENSG00000100614 · UniProtKB:P35813 (PPM1A_HUMAN · PPM1A · P35813 · IPI00216196 · IPI00020950 · PPPM1A)Protein phosphatase 1A⌘
H. sapiensENSEMBL:ENSG00000138032 · UniProtKB:O75688 (IPI00743802 · PPM1B · IPI00026612 · O75688 · PPM1B_HUMAN · PP2CB)Protein phosphatase 1B⌘
H. sapiensENSEMBL:ENSG00000170836 · UniProtKB:O15297 (PPM1D · O15297 · PPM1D_HUMAN · IPI00005782 · WIP1)Protein phosphatase 1D⌘
H. sapiensENSEMBL:ENSG00000175175 · UniProtKB:Q8WY54 (KIAA1072 · IPI00845435 · POPX1 · PPM1E · IPI00845240 · CAMKN · PPM1E_HUMAN · IPI00103630 · Q8WY54)Protein phosphatase 1E⌘
H. sapiensENSEMBL:ENSG00000100034 · UniProtKB:P49593 (PPM1F_HUMAN · IPI00291412 · POPX2 · PPM1F · P49593 · KIAA0015)Protein phosphatase 1F⌘
H. sapiensENSEMBL:ENSG00000115241 · UniProtKB:O15355 (IPI00006167 · PPM1G_HUMAN · PPM1G · PPM1C · O15355)Protein phosphatase 1G⌘
H. sapiensENSEMBL:ENSG00000163644 · UniProtKB:Q8N3J5 (IPI00217525 · PPM1K_HUMAN · IPI00827632 · Q8N3J5 · IPI00292799 · PP2CM · PPM1K)Protein phosphatase 1K, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000163590 · UniProtKB:Q5SGD2 (PPM1L_HUMAN · IPI00657835 · Q5SGD2 · PPM1L · IPI00186145 · PP2CE)Protein phosphatase 1L⌘
H. sapiensENSEMBL:ENSG00000177886 · UniProtKB:Q8N819 (IPI00167290 · Q8N819 · IPI00894383 · IPI00647423 · PPMBL_HUMAN)Probable protein phosphatase 1B-like⌘
M. musculusNCBI:NP_034435 · MGI:MGI:95771 (Gnai1 · Gialpha1)guanine nucleotide binding protein (G protein), alpha inhibiting 1⌘
M. musculusUniProtKB:P21278 · MGI:MGI:95766 (Dsk7 · Gna11)guanine nucleotide binding protein, alpha 11⌘
M. musculusUniProtKB:P27600 · MGI:MGI:95767 (Galpha12 · Gna12)guanine nucleotide binding protein, alpha 12⌘
M. musculusUniProtKB:P27601 · MGI:MGI:95768 (Galpha13 · Gna13)guanine nucleotide binding protein, alpha 13⌘
M. musculusUniProtKB:P30677 · MGI:MGI:95769 (Gna14)guanine nucleotide binding protein, alpha 14 · G alpha 14⌘
M. musculusUniProtKB:P30678 · MGI:MGI:95770 (G[a]15 · Galpha15 · Gna15)guanine nucleotide binding protein, alpha 15⌘
M. musculusUniProtKB:P08752 · MGI:MGI:95772 (Galphai2 · Gnai-2 · Gnai2 · Gia)guanine nucleotide binding protein (G protein), alpha inhibiting 2⌘
M. musculusUniProtKB:Q9DC51 · MGI:MGI:95773 (Galphai3 · Gnai3)guanine nucleotide binding protein (G protein), alpha inhibiting 3⌘
M. musculusUniProtKB:Q8CGK7 · MGI:MGI:95774 (Gna10 · Gnal · Galphaolf · Golf)guanine nucleotide binding protein, alpha stimulating, olfactory type · G alpha 10⌘
M. musculusUniProtKB:P18872 · MGI:MGI:95775 (alphaO · Gnao1)Go alpha · guanine nucleotide binding protein, alpha O⌘
M. musculusUniProtKB:P21279 · MGI:MGI:95776 (Dsk1 · GqI · Gnaq · Gq · Dsk10 · Galphaq)G alpha q · guanine nucleotide binding protein, alpha q polypeptide⌘
M. musculusUniProtKB:Q6R0H7 · MGI:MGI:95777 (Gnasxl · Oedsml · Nesp55 · P2 · PHP1A · P1 · Gsa · Gnas · XLalphas · Nespl · P3 · Nesp · PHP1B · Gnas1 · Gs-alpha)Gs alpha · G alpha s · GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus · neuroendocrine-specific Golgi protein p55 isoform 1⌘
M. musculusUniProtKB:P20612 · MGI:MGI:95778 (transducin · Tralpha · Gnat1 · Gnat-1)guanine nucleotide binding protein, alpha transducing 1⌘
M. musculusUniProtKB:P50149 · MGI:MGI:95779 (Gnat2 · Gt-2 · Gnat-2 · Tcalpha)guanine nucleotide binding protein, alpha transducing 2⌘
M. musculusUniProtKB:Q3V3I2 · MGI:MGI:3588268 (Ggust · alpha-gustducin · Gnat3 · Gtn)guanine nucleotide binding protein, alpha transducing 3⌘
M. musculusUniProtKB:O70443 · MGI:MGI:95780 (Gz · Gnaz)guanine nucleotide binding protein, alpha z subunit⌘
M. musculusUniProtKB:Q8R0F6 · MGI:MGI:1914694 (PP2C-DELTA · Ilkap)integrin-linked kinase-associated serine/threonine phosphatase 2C⌘
M. musculusUniProtKB:P49443 · MGI:MGI:99878 (Ppm1a · MPPa-1 · MMPa-2)Mpp alpha · protein phosphatase 1A, magnesium dependent, alpha isoform⌘
M. musculusUniProtKB:P36993 · MGI:MGI:101841 (Ppm1b · PP2CB)protein phosphatase 1B, magnesium dependent, beta isoform⌘
M. musculusUniProtKB:Q9QZ67 · MGI:MGI:1858214 (Wip1 · Ppm1d)protein phosphatase 1D magnesium-dependent, delta isoform⌘
M. musculusUniProtKB:Q80TL0 · MGI:MGI:2444096 (POPX1 · Ppm1e · PP2CH)protein phosphatase 1E (PP2C domain containing)⌘
M. musculusUniProtKB:Q8CGA0 · MGI:MGI:1918464 (Ppm1f)protein phosphatase 1F (PP2C domain containing)⌘
M. musculusUniProtKB:Q61074 · MGI:MGI:106065 (Fin13 · Ppm1g)protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform⌘
M. musculusUniProtKB:Q8BXN7 · MGI:MGI:2442111 (PP2Cm · Ppm1k)protein phosphatase 1K (PP2C domain containing)⌘
M. musculusUniProtKB:Q8BHN0 · MGI:MGI:2139740 (Pp2ce · PP2C-epsilon · Ppm1l)protein phosphatase 1 (formerly 2C)-like⌘
M. musculusUniProtKB:Q8BGL1 · MGI:MGI:2142330 (C79127)expressed sequence C79127⌘
R. norvegicusNCBI:XP_001066833 · RGD:1305220 (Ppm1l)protein phosphatase 1 (formerly 2C)-like⌘
R. norvegicusNCBI:XP_213418 · RGD:1305460 (Ppm1d)protein phosphatase 1D magnesium-dependent, delta isoform⌘
R. norvegicusNCBI:XP_001075614 · RGD:1562091
R. norvegicusNCBI:NP_001102250 · RGD:1304683 (Gnat1)guanine nucleotide binding protein, alpha transducing 1⌘
R. norvegicusNCBI:XP_345272 · RGD:1309514 (Gnat2)guanine nucleotide binding protein, alpha transducing 2⌘
R. norvegicusNCBI:XP_231833 · RGD:1308501 (Ppm1k)protein phosphatase 1K (PP2C domain containing)⌘
R. norvegicusNCBI:XP_341627 · RGD:1305940
R. norvegicusUniProtKB:Q9JID2 · RGD:619749 (Gna11)guanine nucleotide binding protein, alpha 11⌘
R. norvegicusUniProtKB:Q63210 · RGD:71018 (Gna12)guanine nucleotide binding protein, alpha 12⌘
R. norvegicusUniProtKB:O88302 · RGD:619751 (Gna15)guanine nucleotide binding protein, alpha 15⌘
R. norvegicusUniProtKB:P10824 · RGD:2713 (Gnai1)guanine nucleotide binding protein (G protein), alpha inhibiting 1⌘
R. norvegicusUniProtKB:P04897 · RGD:620243 (Gnai2)guanine nucleotide binding protein (G protein), alpha inhibiting 2⌘
R. norvegicusUniProtKB:P08753 · RGD:2714 (Gnai3)guanine nucleotide binding protein (G protein), alpha inhibiting 3⌘
R. norvegicusUniProtKB:P38406 · RGD:2715 (Gnal)guanine nucleotide binding protein, alpha stimulating, olfactory type⌘
R. norvegicusRGD:628732 (Gnao1) · UniProtKB:P59215 (Gnao · IPI00231505 · Gna0 · GNAO_RAT · IPI00204843 · Gnao1 · P59215)guanine nucleotide binding protein, alpha O polypeptide 1 · Guanine nucleotide-binding protein G(o) subunit alpha⌘⌘
R. norvegicusUniProtKB:P82471 · RGD:620770 (Gnaq)guanine nucleotide binding protein, alpha q polypeptide⌘
R. norvegicusRGD:2716 (Gnas) · UniProtKB:Q63803 (IPI00464920 · Q63803 · GNAS1_RAT · Gnas1 · Gnas)GNAS complex locus · Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas⌘⌘
R. norvegicusUniProtKB:P29348 · RGD:727817 (Gnat3)guanine nucleotide binding protein, alpha transducing 3⌘
R. norvegicusUniProtKB:P19627 · RGD:2717 (Gnaz)guanine nucleotide binding protein, alpha z polypeptide⌘
R. norvegicusUniProtKB:Q9Z1Z6 · RGD:620128 (Ilkap)integrin-linked kinase-associated serine/threonine phosphatase 2C⌘
R. norvegicusUniProtKB:P20650 · RGD:3373 (Ppm1a)protein phosphatase 1A, magnesium dependent, alpha isoform⌘
R. norvegicusRGD:3374 (Ppm1b) · UniProtKB:P35815 (Pp2c2 · PPM1B_RAT · IPI00480583 · P35815 · IPI00560728 · Ppm1b · Pppm1b)protein phosphatase 1B, magnesium dependent, beta isoform · Protein phosphatase 1B⌘⌘
R. norvegicusUniProtKB:Q80Z30 · RGD:735028 (Ppm1e)protein phosphatase 1E (PP2C domain containing)⌘
R. norvegicusUniProtKB:Q9WVR7 · RGD:631363 (Ppm1f)protein phosphatase 1F (PP2C domain containing)⌘
R. norvegicusUniProtKB:Q5EAP4 · RGD:1308122 (Gna14)guanine nucleotide binding protein, alpha 14⌘
R. norvegicusUniProtKB:Q6Q7Y5 · RGD:1310221 (Gna13)guanine nucleotide binding protein, alpha 13⌘
R. norvegicusUniProtKB:Q8K3W9 · RGD:628676 (Ppm1g)protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform⌘
S. cerevisiaeUniProtKB:P08539 · SGD:S000001047 (DAC1 · SCG1 · YHR005C · CDC70 · GPA1)GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors⌘
S. cerevisiaeUniProtKB:P10823 · SGD:S000000822 (YER020W · GPA2 · SSP101)Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients⌘
S. cerevisiaeUniProtKB:P35182 · SGD:S000002164 (KCS2 · YDL006W · TPD1 · CWH47 · PTC1)Type 2C protein phosphatase (PP2C)⌘
S. cerevisiaeUniProtKB:P39966 · SGD:S000000891 (PTC2 · YER089C)Type 2C protein phosphatase⌘
S. cerevisiaeUniProtKB:P34221 · SGD:S000000152 (PTC3 · YBL056W)Type 2C protein phosphatase⌘
S. cerevisiaeUniProtKB:P38089 · SGD:S000000329 (YBR125C · PTC4 · GCT1)Cytoplasmic type 2C protein phosphatase⌘
S. cerevisiaeUniProtKB:Q12511 · SGD:S000005616 (YOR090C · PPP1 · PTC5)Mitochondrial type 2C protein phosphatase involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the ser-133 residue of the Pda1p subunit⌘
S. pombeUniProtKB:P27584 · GeneDB_Spombe:SPBC24C6.06 (gpa1 · SPBC24C6.06)G-protein alpha subunit⌘
S. pombeUniProtKB:Q04665 · GeneDB_Spombe:SPAC23H3.13c (SPAC23H3.13c · gpa2 · git8)heterotrimeric G protein alpha-2 subunit Gpa2⌘
S. pombeUniProtKB:P40371 · GeneDB_Spombe:SPCC4F11.02 (ptc1 · SPCC4F11.02)protein phosphatase 2C Ptc1⌘
S. pombeUniProtKB:Q09172 · GeneDB_Spombe:SPCC1223.11 (SPCC1223.11 · ptc2)protein phosphatase 2C Ptc2⌘
S. pombeUniProtKB:Q09173 · GeneDB_Spombe:SPAC2G11.07c (SPAC2G11.07c · ptc3)protein phosphatase 2C Ptc3⌘
S. pombeUniProtKB:O14156 · GeneDB_Spombe:SPAC4A8.03c (ptc4 · SPAC4A8.03c)protein phosphatase 2C Ptc4⌘
S. pombeUniProtKB:O14189 · GeneDB_Spombe:SPAC10F6.17c (SPAC10F6.17c · SPAC56E4.01c)mitochondrial pyruvate dehydrogenase⌘
ProteinPublicationCurator Notes
UniProtKB:P35182 · SGD:S000002164PMID:8898906 Bertauche N, et al. Protein phosphatase activity of abscisic acid insensitive 1 (ABI1) protein from Arabidopsis thaliana. Eur J Biochem. 1996 Oct 1;241(1):193-200.The A. thaliana protein AT4G26080.1 complements a homologous mutation in S. cerevisiae. This paper shows that a truncated form of A. thaliana ABI1 complements a yeast ptc1 mutant.
UniProtKB:P08539 · SGD:S000001047PMID:2111439 Kang YS, et al. Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol. 1990 Jun;10(6):2582-90.The R. norvegicus protein Galphas complements a homologous mutation in S. cerevisiae. Partially complements the growth and morphological phenotypes, but cells are still sterile.
UniProtKB:P08539 · SGD:S000001047PMID:3113738 Dietzel C, et al. The yeast SCG1 gene: a G alpha-like protein implicated in the a- and alpha-factor response pathway. Cell. 1987 Sep 25;50(7):1001-10.The R. norvegicus protein Galphas complements a homologous mutation in S. cerevisiae.
UniProtKB:P35182 · SGD:S000002164PMID:9649525 Hansen D, et al. Molecular evolution of a sex determination protein. FEM-2 (pp2c) in Caenorhabditis. Genetics. 1998 Jul;149(3):1353-62.The C. elegans protein T19C3.8 complements a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:8943324 Spain BH, et al. Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells. Mol Cell Biol. 1996 Dec;16(12):6698-706.The H. sapiens protein Gsalpha (protein ID unknown) was expressed in S. cerevisiae, but complementation was not directly tested. Human Gsalpha suppresses a yeast gpa1 mutant.
UniProtKB:P08539 · SGD:S000001047PMID:2111439 Kang YS, et al. Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol. 1990 Jun;10(6):2582-90.The R. norvegicus protein Galphai complements a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:2111439 Kang YS, et al. Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol. 1990 Jun;10(6):2582-90.The R. norvegicus protein Galphao complements a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:8943324 Spain BH, et al. Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells. Mol Cell Biol. 1996 Dec;16(12):6698-706.The H. sapiens protein Q13098 was expressed in S. cerevisiae, but complementation was not directly tested. Expression of the carboxy terminal half of human gps1 suppresses a yeast gpa1 mutant.
UniProtKB:P08539 · SGD:S000001047PMID:8943324 Spain BH, et al. Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells. Mol Cell Biol. 1996 Dec;16(12):6698-706.The H. sapiens protein Q13227 was expressed in S. cerevisiae, but complementation was not directly tested. Human gps2 suppresses a yeast gpa1 mutant.
UniProtKB:P39966 · SGD:S000000891PMID:15480788 Valkonen M, et al. The ire1 and ptc2 genes involved in the unfolded protein response pathway in the filamentous fungus Trichoderma reesei. Mol Genet Genomics. 2004 Nov;272(4):443-51.The T. reesei protein PTC2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:2111439 Kang YS, et al. Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol. 1990 Jun;10(6):2582-90.The R. norvegicus protein Gnao does not complement a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:2111439 Kang YS, et al. Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol. 1990 Jun;10(6):2582-90.The R. norvegicus protein Gnas complements a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:2111439 Kang YS, et al. Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol. 1990 Jun;10(6):2582-90.The R. norvegicus protein Gnai2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P08539 · SGD:S000001047PMID:3113738 Dietzel C, et al. The yeast SCG1 gene: a G alpha-like protein implicated in the a- and alpha-factor response pathway. Cell. 1987 Sep 25;50(7):1001-10.The R. norvegicus protein Gnas complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (5)
ENSEMBL:ENSG00000087460 · UniProtKB:Q5JWF2+139320 GNAS COMPLEX LOCUS; GNAS;;GNAS1 GENE, FORMERLY; GNAS1, FORMERLYGUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-STIMULATING ACTIVITY POLYPEPTIDE1, INCLUDED; GNAS1, INCLUDED;;Gs, ALPHA SUBUNIT, INCLUDED;;STIMULATORY G PROTEIN, INCLUDED;;ADENYLATE CYCLASE STIMULATORY PROTEIN, ALPHA SUBUNIT, INCLUDED;;SECRETOGRANIN VI, INCLUDED;;NEUROENDOCRINE SECRETORY PROTEIN 55, INCLUDED; NESP55, INCLUDED;;XL-ALPHA-S, INCLUDED; XLAS, INCLUDED;;A/B TRANSCRIPT, INCLUDED;;ALTERNATIVE GENE PRODUCT ENCODED BY THE XL EXON, INCLUDED; ALEX, INCLUDED;;PROLONGED BLEEDING TIME, BRACHYDACTYLY, AND MENTAL RETARDATION, INCLUDED
ENSEMBL:ENSG00000114349 · UniProtKB:P11488#603233 PSEUDOHYPOPARATHYROIDISM, TYPE IB; PHP1B;;PHP IB
#219080 ACTH-INDEPENDENT MACRONODULAR ADRENAL HYPERPLASIA; AIMAH;;ACTH-INDEPENDENT MACRONODULAR ADRENOCORTICAL HYPERPLASIA;;ADRENOCORTICOTROPIC HORMONE-INDEPENDENT MACRONODULAR ADRENAL HYPERPLASIA;;CORTICOTROPIN-INDEPENDENT MACRONODULAR ADRENAL HYPERPLASIA;;ACTH-INDEPENDENT CUSHING SYNDROME;;CUSHING SYNDROME, ADRENAL, DUE TO AIMAH
ENSEMBL:ENSG00000134183 · UniProtKB:P19087#610444 NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 3; CSNBAD3;;NIGHT BLINDNESS, CONGENITAL STATIONARY, NOUGARET TYPE
UniProtKB:P08539 · SGD:S000001047+139340 GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-TRANSDUCING ACTIVITY POLYPEPTIDE2; GNAT2;;G PROTEIN, ALPHA-TRANSDUCING 2;;TRANSDUCIN, CONE-SPECIFIC, ALPHA POLYPEPTIDEACHROMATOPSIA 4, INCLUDED; ACHM4, INCLUDED
SGD Disease Papers (8)
UniProtKB:P08539 · SGD:S000001047PMID:9786851 Apanovitch DM, et al. (1998) Second site suppressor mutations of a GTPase-deficient G-protein alpha-subunit. Selective inhibition of Gbeta gamma-mediated signaling. J Biol Chem 273(44):28597-602
PMID:2829196 Levine MA, et al. (1988) Genetic deficiency of the alpha subunit of the guanine nucleotide-binding protein Gs as the molecular basis for Albright hereditary osteodystrophy. Proc Natl Acad Sci U S A 85(2):617-21
PMID:2122458 Weinstein LS, et al. (1990) Mutations of the Gs alpha-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis. Proc Natl Acad Sci U S A 87(21):8287-90
PMID:2116665 Lyons J, et al. (1990) Two G protein oncogenes in human endocrine tumors. Science 249(4969):655-9
PMID:17132542 Ooms LS, et al. (2006) Identification of a second-site suppressor mutation of the GTPase defect associated with McCune - Albright syndrome: A model using the yeast heterotrimeric G protein, GPA1. Arch Physiol Biochem 112(3):166-73
PMID:11853883 Kong JL, et al. (2002) Inhibition of somatostatin receptor 5-signaling by mammalian regulators of G-protein signaling (RGS) in yeast. Biochim Biophys Acta 1542(1-3):95-105
PMID:11389184 Erlenbach I, et al. (2001) Functional expression of M(1), M(3) and M(5) muscarinic acetylcholine receptors in yeast. J Neurochem 77(5):1327-37
PMID:10620771 Brown AJ, et al. (2000) Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras. Yeast 16(1):11-22
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