P-POD: Princeton Protein Orthology Database: GO3/Jaccard39

This family has 316 members: 56 Arabidopsis thaliana, 26 Caenorhabditis elegans, 31 Danio rerio, 24 Dictyostelium discoideum, 28 Drosophila melanogaster, 1 Escherichia coli, 27 Gallus gallus, 28 Homo sapiens, 29 Mus musculus, 26 Rattus norvegicus, 20 Saccharomyces cerevisiae, 20 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Jaccard39
316 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_180328.1 · TAIR:locus:2038678 (F10A12_27 · F10A12.27 · AT2G27600 · VPS4 · SKD1)VACUOLAR PROTEIN SORTING 4 · SUPPRESSOR OF K+ TRANSPORT GROWTH DEFECT1⌘
A. thalianaNCBI:NP_175120.1 · TAIR:locus:2028200 (AT1G45000 · F27F5_8 · F27F5.8)⌘
A. thalianaNCBI:NP_194529.1 · TAIR:locus:2132922 (T13J8_110 · AT4G28000 · T13J8.110)⌘
A. thalianaNCBI:NP_194633.1 · TAIR:locus:2119926 (F19B15_70 · RPT2a · F19B15.70 · AT4G29040)regulatory particle AAA-ATPase 2a · 26S PROTEASOME AAA-ATPASE SUBUNIT RPT2A⌘
A. thalianaNCBI:NP_566889.1 · TAIR:locus:2075581 (F13I12.110 · ftsh7 · AT3G47060)FtsH protease 7⌘
A. thalianaNCBI:NP_175781.1 · TAIR:locus:2197066 (T18A20_2 · T18A20.2 · AT1G53780)⌘
A. thalianaNCBI:NP_567238.2 · TAIR:locus:2133298 (T14P8.8 · T14P8_8 · AT4G02470 · AT4G02480)⌘
A. thalianaNCBI:NP_566541.1 · TAIR:locus:2094892 (EMB2083 · MYA6.12 · AT3G16290)embryo defective 2083⌘
A. thalianaNCBI:NP_171788.2 · TAIR:locus:2024655 (F22D16.11 · F22D16_11 · AT1G02890)⌘
A. thalianaNCBI:NP_187595.1 · TAIR:locus:2085064 (AT3G09840 · CDC48 · ATCDC48 · CDC48A · F8A24.11)CELL DIVISION CYCLE 48⌘
A. thalianaNCBI:NP_194498.1 · TAIR:locus:2137777 (AT4G27680 · T29A15_170 · T29A15.170)⌘
A. thalianaNCBI:NP_196464.2 · TAIR:locus:2159557 (F8L15.15 · AT5G08470 · PEX1)peroxisome 1⌘
A. thalianaNCBI:NP_172231.2 · TAIR:locus:2025052 (F22G5_10 · F22G5.10 · ftsh10 · AT1G07510)FtsH protease 10⌘
A. thalianaNCBI:NP_568311.2 · TAIR:locus:2150926 (F8M21_140 · FTSH6 · ATFTSH6 · F8M21.140 · AT5G15250)FTSH PROTEASE 6⌘
A. thalianaNCBI:NP_176404.2 · TAIR:locus:2018102 (F19K23.7 · F19K23_7 · AT1G62130)⌘
A. thalianaNCBI:NP_171799.2 · TAIR:locus:2007574 (F10O3.18 · PEX6 · F10O3_18 · AT1G03000)PEROXIN 6⌘
A. thalianaNCBI:NP_565212.1 · TAIR:locus:2206380 (T8K14_2 · T8K14.2 · FTSH12 · EMB1047 · AT1G79560)FTSH PROTEASE 12 · EMBRYO DEFECTIVE 1047⌘
A. thalianaNCBI:NP_199115.1 · TAIR:locus:2159996 (MBD2_21 · MBD2.21 · RPT4A · AT5G43010)⌘
A. thalianaNCBI:NP_191228.1 · TAIR:locus:2103555 (CIP111 · T8M16.20 · AT3G56690)CAM INTERACTING PROTEIN 111⌘
A. thalianaNCBI:NP_194217.2 · TAIR:locus:2126783
A. thalianaNCBI:NP_175778.1 · TAIR:locus:2024822 (RPT1A · T18A20_1 · T18A20.1 · AT1G53750)26S PROTEASOME ATPASE SUBUNIT · REGULATORY PARTICLE TRIPLE-A 1A⌘
A. thalianaNCBI:NP_568604.1 · TAIR:locus:2157637 (VAR1 · K5J14.13 · FTSH5 · AT5G42270 · K5J14_13)VARIEGATED 1⌘
A. thalianaNCBI:NP_188608.3 · TAIR:locus:2091151 (MMB12.22 · AT3G19740)⌘
A. thalianaNCBI:NP_186810.2 · TAIR:locus:2084163 (F4P13_15 · emb1354 · F4P13.15 · CDC48C · AT3G01610)embryo defective 1354⌘
A. thalianaNCBI:NP_200166.1 · TAIR:locus:2168646 (MNC6.8 · AT5G53540 · MNC6_8)⌘
A. thalianaNCBI:NP_192327.3 · TAIR:locus:2137261 (T27D20_13 · T27D20.13 · AT4G04180)⌘
A. thalianaNCBI:NP_568114.1 · TAIR:locus:2831844 (F12E4_70 · F12E4.70 · AT5G03340)⌘
A. thalianaNCBI:NP_850129.1 · TAIR:locus:2066128 (ftsh3 · AT2G29080 · T9I4_16 · T9I4.16)FtsH protease 3⌘
A. thalianaNCBI:NP_188130.1 · TAIR:locus:2083681 (AT3G15120 · F4B12.4)⌘
A. thalianaNCBI:NP_186894.1 · TAIR:locus:2076929 (AT3G02450 · F16B3_8 · F16B3.8)⌘
A. thalianaNCBI:NP_200637.1 · TAIR:locus:2161258 (AT5G58290 · MCK7.16 · RPT3 · MCK7_16)REGULATORY PARTICLE TRIPLE-A ATPASE 3 · 26S PROTEASOME AAA-ATPASE SUBUNIT RPT3⌘
A. thalianaNCBI:NP_563766.3 · TAIR:locus:2009235 (FTSH8 · AT1G06430 · F12K11.22)FTSH PROTEASE 8⌘
A. thalianaNCBI:NP_563753.1 · TAIR:locus:2198748 (T20M3.19 · T20M3_19 · AT1G05910)⌘
A. thalianaNCBI:NP_001078747.1 · TAIR:locus:4010714050 (AT5G52882)⌘
A. thalianaNCBI:NP_189348.3 · TAIR:locus:2092025 (MOJ10.20 · AT3G27120)⌘
A. thalianaNCBI:NP_568892.1 · TAIR:locus:2154568 (K19M22.17 · AT5G58870 · K19M22_17 · ftsh9)FtsH protease 9⌘
A. thalianaNCBI:NP_179604.1 · TAIR:locus:2061639 (T2G17.6 · T2G17_6 · AT2G20140)⌘
A. thalianaNCBI:NP_172384.1 · TAIR:locus:2036099 (RPT5B · F7G19.2 · F7G19_2 · AT1G09100)26S proteasome AAA-ATPase subunit RPT5B⌘
A. thalianaNCBI:NP_568389.1 · TAIR:locus:2147670 (AT5G19990 · RPT6A · F28I16.140 · F28I16_140 · ATSUG1)26S PROTEASOME AAA-ATPASE SUBUNIT · REGULATORY PARTICLE TRIPLE-A ATPASE 6A⌘
A. thalianaNCBI:NP_192447.1 · TAIR:locus:2115954 (C6L9_60 · AT4G05380 · C6L9.60)⌘
A. thalianaNCBI:NP_175433.2 · TAIR:locus:2031005 (F2J10.1 · AT1G50140 · F2J10_1)⌘
A. thalianaNCBI:NP_567691.1 · TAIR:locus:2138146 (T32A16.110 · T32A16_110 · AT4G23940)⌘
A. thalianaNCBI:NP_178463.1 · TAIR:locus:2044209 (CDC48B · F19B11_12 · F19B11.12 · AT2G03670 · T4D2.160)⌘
A. thalianaNCBI:NP_182074.4 · TAIR:locus:2043619 (F17K2.3 · AT2G45500)⌘
A. thalianaNCBI:NP_192400.2 · TAIR:locus:2135378
A. thalianaNCBI:NP_973600.1 · TAIR:locus:2062274 (T31E10.10 · AT2G34560 · T31E10_10)⌘
A. thalianaNCBI:NP_190891.1 · TAIR:locus:2101933 (AT3G53230 · T4D2.160)⌘
A. thalianaNCBI:NP_564563.1 · TAIR:locus:2011952 (AT1G50250 · FTSH1 · F14I3_14 · F14I3.14)FtsH protease 1⌘
A. thalianaNCBI:NP_565616.1 · TAIR:locus:2057386 (T19L18.5 · T19L18_5 · ftsh4 · AT2G26140)FtsH protease 4⌘
A. thalianaNCBI:NP_178151.1 · TAIR:locus:2034230 (LUE1 · AT1G80350 · KTN1 · AtKSS · F5I6_10 · ERH3 · BOT1 · AAA1 · FRC2 · FTR · F5I6.10 · ATKTN1 · FURCA2 · FRA2)Arabidopsis thaliana katanin small subunit · BOTERO 1 · CAD ATPASE · KATANIN 1 · FRAGILE FIBER 2 · FAT ROOT · ECTOPIC ROOT HAIR 3⌘
A. thalianaNCBI:NP_849842.1 · TAIR:locus:2024522 (F22C12.12 · F22C12_12 · AT1G64110)⌘
A. thalianaNCBI:NP_197500.1 · TAIR:locus:2147685 (AT5G20000 · F28I16.150 · F28I16_150)⌘
A. thalianaNCBI:NP_187204.1 · TAIR:locus:2079742 (F22F7_1 · ATS6A.2 · RPT5A · F22F7.1 · AT3G05530)26s proteasome aaa-atpase subunit · REGULATORY PARTICLE TRIPLE-A ATPASE 5A · 19s proteasome regulatory complex subunit s6a⌘
A. thalianaNCBI:NP_568787.1 · TAIR:locus:2163736 (MFH8_11 · MFH8.11 · AT5G53170 · FTSH11)FtsH protease 11⌘
A. thalianaNCBI:NP_850156.1 · TAIR:locus:2052806 (F7F1.16 · AT2G30950 · FTSH2 · F7F1_16 · VAR2)VARIEGATED 2⌘
A. thalianaNCBI:NP_201263.2 · TAIR:locus:2174819 (MUB3.10 · MUB3_10 · AT5G64580)⌘
C. elegansWB:WBGene00017981 (figl-1 · F32D1.1) · UniProtKB:O16299 (FIGL1_CAEEL · figl-1 · F32D1.1)Fidgetin-like protein 1⌘⌘
C. elegansWB:WBGene00003183 (T01G9.5 · mei-1) · UniProtKB:P34808 (MEI1_CAEEL · T01G9.5 · mei-1)Meiotic spindle formation protein mei-1⌘⌘
C. elegansWB:WBGene00010557 (K04D7.2 · mspn-1) · UniProtKB:P54815 (MSP1_CAEEL · K04D7.2)Protein MSP1 homolog⌘⌘
C. elegansWB:WBGene00003818 (nsf-1 · H15N14.2) · UniProtKB:Q94392 (nsf-1 · H15N14.2 · NSF_CAEEL)Vesicle-fusing ATPase⌘⌘
C. elegansWB:WBGene00004504 (F23F1.8 · rpt-4) · UniProtKB:O17071 (F23F1.8 · rpt-4 · PRS10_CAEEL)Probable 26S protease regulatory subunit S10B⌘⌘
C. elegansWB:WBGene00004502 (rpt-2 · F29G9.5) · UniProtKB:O16368⌘
C. elegansWB:WBGene00004503 (rpt-3 · F23F12.6) · UniProtKB:P46502⌘
C. elegansWB:WBGene00004501 (rpt-1 · C52E4.4) · UniProtKB:Q18787 (PRS7_CAEEL · rpt-1 · C52E4.4)26S protease regulatory subunit 7⌘⌘
C. elegansWB:WBGene00008682 (F11A10.1 · lex-1) · UniProtKB:P54816⌘
C. elegansWB:WBGene00007352 (C06A1.1 · cdc-48.1) · UniProtKB:P54811 (TERA1_CAEEL · C06A1.1 · cdc-48.1)Transitional endoplasmic reticulum ATPase homolog 1⌘⌘
C. elegansWB:WBGene00008053 (C41C4.8 · cdc-48.2) · UniProtKB:P54812 (TERA2_CAEEL · C41C4.8 · cdc-48.2)Transitional endoplasmic reticulum ATPase homolog 2⌘⌘
C. elegansWB:WBGene00010842 (M03C11.5 · ymel-1) · UniProtKB:P54813⌘
C. elegansWB:WBGene00004195 (F39G3.7 · prx-6) · UniProtKB:O16270⌘
C. elegansWB:WBGene00004505 (rpt-5 · F56H1.4) · UniProtKB:O76371⌘
C. elegansWB:WBGene00015688 (C10G11.8) · UniProtKB:P91025⌘
C. elegansWB:WBGene00004191 (C11H1.4 · prx-1) · UniProtKB:Q17916⌘
C. elegansWB:WBGene00021425 (ppgn-1 · Y38F2AR.7) · UniProtKB:Q18NR5⌘
C. elegansWB:WBGene00010562 (cdc-48.3 · K04G2.3) · UniProtKB:Q21222⌘
C. elegansWB:WBGene00016045 (spas-1 · C24B5.2) · UniProtKB:Q8MNV0⌘
C. elegansWB:WBGene00018991 (F56F11.4) · UniProtKB:Q8MXF1⌘
C. elegansWB:WBGene00022429 · UniProtKB:Q965V5
C. elegansUniProtKB:Q965V5 · WB:WBGene00021615
C. elegansWB:WBGene00021334 (Y34D9A.10 · vps-4) · UniProtKB:Q9BL83⌘
C. elegansWB:WBGene00004978 (Y47G6A.10 · spg-7) · UniProtKB:Q9N3T5⌘
C. elegansWB:WBGene00003119 (mac-1 · Y48C3A.7) · UniProtKB:Q9NAG4⌘
C. elegansWB:WBGene00004506 (Y49E10.1 · rpt-6) · UniProtKB:Q9XTT9⌘
D. rerioENSEMBL:ENSDARP00000059420
D. rerioENSEMBL:ENSDARP00000095384
D. rerioENSEMBL:ENSDARP00000074113
D. rerioENSEMBL:ENSDARP00000094195
D. rerioENSEMBL:ENSDARP00000017944
D. rerioENSEMBL:ENSDARP00000084267
D. rerioENSEMBL:ENSDARP00000074407
D. rerioENSEMBL:ENSDARP00000036813
D. rerioUniProtKB:Q7ZZ25 · ZFIN:ZDB-GENE-030616-593 (atad1a)ATPase family, AAA domain containing 1a⌘
D. rerioUniProtKB:Q503W7 · ZFIN:ZDB-GENE-030616-44 (atad1b)ATPase family, AAA domain containing 1b⌘
D. rerioZFIN:ZDB-GENE-050522-339 (fidgetin · fign) · UniProtKB:Q503S1⌘
D. rerioZFIN:ZDB-GENE-041114-141 (zgc:101696) · UniProtKB:Q5U3S1⌘
D. rerioUniProtKB:Q5RII9 · ZFIN:ZDB-GENE-050522-514 (katna1)katanin p60 (ATPase-containing) subunit A 1⌘
D. rerioZFIN:ZDB-GENE-070410-25 (zgc:162158) · UniProtKB:A4QNU8⌘
D. rerioZFIN:ZDB-GENE-060929-204 (zgc:153294) · UniProtKB:Q08CB5⌘
D. rerioZFIN:ZDB-GENE-060312-22 (zgc:136908) · UniProtKB:Q29RA2⌘
D. rerioUniProtKB:Q4U0S6 · ZFIN:ZDB-GENE-050808-1 (nsfb)N-ethylmaleimide-sensitive factor b⌘
D. rerioUniProtKB:Q6AZC1 · ZFIN:ZDB-GENE-030131-6547 (psmc5)proteasome (prosome, macropain) 26S subunit, ATPase, 5⌘
D. rerioUniProtKB:Q6DRD2 · ZFIN:ZDB-GENE-030131-304 (psmc6)proteasome (prosome, macropain) 26S subunit, ATPase, 6⌘
D. rerioUniProtKB:Q6IQ72 · ZFIN:ZDB-GENE-040625-69 (psmc1b)proteasome (prosome, macropain) 26S subunit, ATPase, 1b⌘
D. rerioUniProtKB:Q6IQL5 · ZFIN:ZDB-GENE-030131-666 (psmc3)proteasome (prosome, macropain) 26S subunit, ATPase, 3⌘
D. rerioZFIN:ZDB-GENE-040426-2331 (spast · spastin) · UniProtKB:Q6NW58⌘
D. rerioUniProtKB:Q7SXX0 · ZFIN:ZDB-GENE-030131-5083 (psmc4)proteasome (prosome, macropain) 26S subunit, ATPase, 4⌘
D. rerioENSEMBL:ENSDARG00000069175 · UniProtKB:Q7SXY0
D. rerioUniProtKB:Q7SXY0 · ENSEMBL:ENSDARG00000070706
D. rerioUniProtKB:Q7T3B1 · ZFIN:ZDB-GENE-040426-1327 (psmc2)proteasome (prosome, macropain) 26S subunit, ATPase 2⌘
D. rerioUniProtKB:Q7ZU50 · ZFIN:ZDB-GENE-030616-37 (nsf)N-ethylmaleimide-sensitive factor⌘
D. rerioUniProtKB:Q7ZWD1 · ZFIN:ZDB-GENE-030131-8730 (psmc1a)proteasome (prosome, macropain) 26S subunit, ATPase, 1a⌘
D. rerioUniProtKB:Q803I9 · ZFIN:ZDB-GENE-040426-2871 (nvl)nuclear VCP-like⌘
D. rerioUniProtKB:Q08BZ6 · ZFIN:ZDB-GENE-060929-388 (vps4a)vacuolar protein sorting 4a (yeast)⌘
D. rerioUniProtKB:Q7ZU99 · ZFIN:ZDB-GENE-030131-5408 (vcp)valosin containing protein⌘
D. discoideumNCBI:EAL62534.1 · dictyBase:DDB_G0289867 (pex1)peroxisomal biogenesis factor 1, peroxin 1⌘
D. discoideumNCBI:EAL61068.1 · dictyBase:DDB_G0292788 (pex6)peroxin 6, peroxisomal biogenesis factor 6, AAA ATPase domain-containing protein⌘
D. discoideumNCBI:EAL73199.1 · dictyBase:DDB_G0267492 (DDB_G0267492)Putative FtsH protease.⌘
D. discoideumUniProtKB:Q75JI3 · dictyBase:DDB_G0276153 (nsf · nsfA)N-ethylmaleimide-sensitive fusion protein⌘
D. discoideumUniProtKB:Q54PJ1 · dictyBase:DDB_G0284517 (psmC6)26S protease regulatory subunit S10B, 26S proteasome subunit ATPase 6⌘
D. discoideumUniProtKB:Q55BV5 · dictyBase:DDB_G0270784 (DdTBPalpha · psmC1)26S proteasome ATPase 1 subunit, 26S protease regulatory subunit 4, TAT binding protein alpha⌘
D. discoideumUniProtKB:P34123 · dictyBase:DDB_G0289003 (TBP2 · tbpB · psmC4)26S protease regulatory subunit 6B, 26S proteasome subunit ATPase 4, HIV TAT binding-protein-related⌘
D. discoideumUniProtKB:Q86JA1 · dictyBase:DDB_G0276917 (psmC2)26S proteasome ATPase 2 subunit, 26S protease regulatory subunit 7⌘
D. discoideumUniProtKB:P34124 · dictyBase:DDB_G0292382 (tbpC · TBP10 · psmC5)26S proteasome subunit ATPase 5, 26S protease regulatory subunit 8, HIV TAT binding-protein-related⌘
D. discoideumUniProtKB:Q54PT2 · dictyBase:DDB_G0284347 (vps4)AAA ATPase domain-containing protein, MIT domain-containing protein⌘
D. discoideumUniProtKB:P90532 · dictyBase:DDB_G0288065 (cdcD · cdc48)cell division cycle protein 48, CDC48 family AAA ATPase⌘
D. discoideumUniProtKB:Q1ZXK7 · dictyBase:DDB_G0276169 (DDB_G0276169)AAA ATPase domain-containing protein⌘
D. discoideumUniProtKB:Q54BW7 · dictyBase:DDB_G0293388 (DDB_G0293388)ATP-dependent metalloprotease⌘
D. discoideumUniProtKB:Q54KQ7 · dictyBase:DDB_G0287165 (DDB_G0287165)AAA ATPase domain-containing protein, MIT domain-containing protein⌘
D. discoideumUniProtKB:Q54PN7 · dictyBase:DDB_G0284415 (psmC3)26S proteasome ATPase 3 subunit, 26S protease regulatory subunit 6A, TAT-binding protein 1⌘
D. discoideumUniProtKB:Q54PX1 · dictyBase:DDB_G0284249 (DDB_G0284249)peptidase M41, FtsH domain-containing protein⌘
D. discoideumUniProtKB:Q54ST1 · dictyBase:DDB_G0282241 (DDB_G0282241)Q9ZPR1 Cell division control protein 48 homolog B (AtCDC48b).⌘
D. discoideumUniProtKB:Q54SY2 · dictyBase:DDB_G0282181 (nvl)AAA ATPase domain-containing protein, nuclear VCP-like protein, valosin-containing protein⌘
D. discoideumUniProtKB:Q54TZ0 · dictyBase:DDB_G0281521 (DDB_G0281521)BRAT group protein, bromodomain-containing protein, AAA ATPase domain-containing protein⌘
D. discoideumUniProtKB:Q54Y38 · dictyBase:DDB_G0278435 (DDB_G0278435)AAA ATPase domain-containing protein⌘
D. discoideumUniProtKB:Q55FK3 · dictyBase:DDB_G0268066 (DDB_G0268066)putative ATPase⌘
D. discoideumUniProtKB:Q55GC3 · dictyBase:DDB_G0268334 (DDB_G0268334)F32D1.1 protein.⌘
D. discoideumUniProtKB:Q75JS8 · dictyBase:DDB_G0272120 (rcaA)peptidase M41, FtsH domain-containing protein⌘
D. discoideumUniProtKB:Q86B10 · dictyBase:DDB_G0272777 (DDB_G0272777)VCP-like ATPase.⌘
D. melanogasterFB:FBgn0031519 (Dm-fidgetin · CG3326 · DmCG3326 · fidgetin_DROME) · UniProtKB:Q9VQN8⌘
D. melanogasterUniProtKB:P46461 · FB:FBgn0000346 (dNSF · NSF-1 · DmNSF · NSF · dnsf1 · dNsf1 · CG1618 · comatose · NSF1 · dNSF-1 · dNSF1 · Nsf · comt · com)CG 1618 · NEM-sensitive fusion protein · N-ethylmaleimide-sensitive fusion protein⌘
D. melanogasterUniProtKB:P54351 · FB:FBgn0013998 (dNSF · dNSF2 · dnsf2 · NSF-2 · Nsf-2 · dNsf2 · CG9931 · DmNSF2 · CG33101 · NSF2 · dNSF-2 · Nsf2)NEM-sensitive fusion protein 2⌘
D. melanogasterUniProtKB:P48601 · FB:FBgn0015282 (p56 · S4 · p54 · Dm-S4-1 · dRpt2 · DmP26S4 · CG5289 · Pros26.4 · pros26.4 · P26s4 · Dm_Rpt2)proteasome 26S · 26S proteasome subunit 4 ATPase · Proteasome 26S subunit subunit 4 ATPase⌘
D. melanogasterUniProtKB:O18413 · FB:FBgn0020369 (Dm_Rpt6a · Dug · DUG · pros45 · sug1 · Pros45 · Ug · dRpt6 · p42C · sug-1 · CG1489)26S proteasome regulatory subunit 8⌘
D. melanogasterUniProtKB:Q7KN62 · FB:FBgn0024923 (Ter94 · VCP · p97 · l(2)46CFs · ter94 · anon-WO2004063362.65 · l(2)46CFf · CG2331 · BcDNA.GM02885 · l(2)46Ch · TER94 · Apple · DmTER94 · 7.12 · l(2)03775 · 22.26 · VCP/p97 · Vcp · BcDNA:GM02885 · pTER94 · CDC48 · I · anon-WO2004063362.67)transitional endoplasmic reticulum ATPase · Valosin-containing protein · valosin-containing protein · Complementation group I⌘
D. melanogasterUniProtKB:Q7KMQ0 · FB:FBgn0028687 (p48B · Rpt1/p48B · Dmp48B · l(2)43Ed · dRpt1 · CG1341 · anon-WO0118547.90 · lethal(2)43Ed · Rpt1 · Dm_Rpt1 · l(2)05643)AAA ATPase⌘
D. melanogasterFB:FBgn0039141 (Spastin · Dspastin · Dm-Spastin · spastin · D-spastin · Spas · CG5977 · spas) · UniProtKB:Q8IMX5⌘
D. melanogasterFB:FBgn0028868 (CG4701 · BG:DS06874.3 · DmDM19DC4Z) · UniProtKB:Q8MZ76⌘
D. melanogasterFB:FBgn0028685 (l(1)G0114 · Rpt4 · p42D · Dm_Rpt4a · Dmp42D · l(1)G0227 · l(1)G0345 · CG3455 · Dm_Rpt4b) · UniProtKB:Q8SZ19⌘
D. melanogasterUniProtKB:Q8SZ40 · FB:FBgn0040208 (CG10229 · Katanin-60 · DmCG10229 · katanin-60 · katanin60-dm · katanin)Katanin 60 · katanin 60⌘
D. melanogasterFB:FBgn0029656 (CG10793) · UniProtKB:Q8T446⌘
D. melanogasterFB:FBgn0036702 (DmCG6512 · CG6512) · UniProtKB:Q8T4G5⌘
D. melanogasterFB:FBgn0028686 (Rpt3 · l(1)G0052 · p48A · Dmp48A · Dm_Rpt3a · CG16916) · UniProtKB:Q9V405⌘
D. melanogasterFB:FBgn0033564 (DmCG11919 · CG11919 · CG30019) · UniProtKB:Q9V5R2⌘
D. melanogasterFB:FBgn0039788 (CG2241 · DmCG2241 · Dm_Rpt6b) · UniProtKB:Q9VA54⌘
D. melanogasterFB:FBgn0037742 (CG9475 · DmCG9475 · Rpt3R · Dm_Rpt3b) · UniProtKB:Q9VH79⌘
D. melanogasterFB:FBgn0032450 (CG5776) · UniProtKB:Q9VK63⌘
D. melanogasterUniProtKB:Q9VL02 · FB:FBgn0005322 (ms(2)ry4 · l(2)08774 · CG5395 · Msp · nmd · DmCG5395 · ms(2)4 · Msp1 · anon-EST:Liang-1.79)clone 1.79 · no mitochondrial derivative · Mitochondrial sorting protein 1⌘
D. melanogasterFB:FBgn0037375 (DmCG1193 · CG1193) · UniProtKB:Q9VNI0⌘
D. melanogasterFB:FBgn0016983 (l(3)j6B8 · smallminded · smid · l(3)j8A6 · l(3)s2898 · CG8571) · UniProtKB:Q9VS62⌘
D. melanogasterFB:FBgn0036224 (CG7257 · Dm_Rpt4c · DmCG7257) · UniProtKB:Q9VTQ9⌘
D. melanogasterFB:FBgn0035443 (CG12010) · UniProtKB:Q9VZQ0⌘
D. melanogasterFB:FBgn0034792 (DmCG3499 · CG3499) · UniProtKB:Q9W1Y0⌘
D. melanogasterFB:FBgn0024992 (paraplegin_DROME · EG:100G10.7 · Dm100G10.aj · anon-3Ba · CG2658) · UniProtKB:Q9W4W8⌘
D. melanogasterUniProtKB:Q9XZC3 · FB:FBgn0028684 (Rpt5 · Dm_Rpt5a · Pros26S · Tbp-1 · anon-WO0153538.9 · Dm_Rpt5b · dRpt5 · Tbp1 · tbp-1 · anon-WO0153538.10 · l(3)04210 · anon-WO0153538.8 · p50 · DmTBP-1 · BcDNA:GH12068 · BcDNA.GH12068 · Pros26S-RS6A · CG10370)Tat-binding protein-1 · Proteasome 26S regulatory subunit 6A⌘
D. melanogasterUniProtKB:Q9Y090 · FB:FBgn0013563 (anon-WO0172774.101 · l(3)s4868 · l(3)084807 · l(3)70Da · 0848/07 · anon-WO0172774.96 · anon-WO0172774.100 · l(3)02402 · CG6760 · DmCAB51031.1 · anon-WO0172774.98 · l(3)S084807 · anon-WO0172774.102 · anon-WO0172774.99)lethal (3) 70Da⌘
D. melanogasterFB:FBgn0027605 (vps4 · Vps4 · DmBcDNA.GH02678 · BcDNA:GH02678 · CG6842 · bcDNA:GH02678) · UniProtKB:Q9Y162⌘
E. coliUniProtKB:P0AAI3 · ECOLI:EG11506-MONOMER (ftsH · hflB · tolZ · std · ECK3167 · HflB · FtsH · b3178 · mrsC)⌘
G. gallusNCBI:XP_415006 · ENTREZ:416709
G. gallusNCBI:XP_419121 · ENTREZ:421036
G. gallusNCBI:XP_421556 · ENTREZ:423676
G. gallusNCBI:XP_420619 · ENTREZ:422665
G. gallusNCBI:XP_423372 · ENTREZ:425637
G. gallusNCBI:XP_414699 · ENTREZ:416384
G. gallusNCBI:XP_425834 · ENTREZ:428274
G. gallusNCBI:XP_428847 · ENTREZ:431296
G. gallusNCBI:XP_426585 · ENTREZ:429028
G. gallusNCBI:XP_413821 · ENTREZ:415441
G. gallusNCBI:XP_418094 · ENTREZ:419972
G. gallusNCBI:XP_418655 · ENTREZ:420554
G. gallusNCBI:XP_419982 · ENTREZ:421972
G. gallusNCBI:XP_001234039 · ENTREZ:420946
G. gallusNCBI:XP_418453 · ENTREZ:420346
G. gallusNCBI:XP_428317 · ENTREZ:430766
G. gallusNCBI:XP_417114 · ENTREZ:418920
G. gallusENTREZ:395804 · UniProtKB:Q90732 (Q90732 · PSMC1 · PRS4_CHICK · IPI00585304)26S protease regulatory subunit 4⌘
G. gallusENTREZ:421626 · UniProtKB:Q1HGK7 (IPI00786289 · KTNA1_CHICK · Q1HGK7 · KATNA1)Katanin p60 ATPase-containing subunit A1⌘
G. gallusUniProtKB:Q5F3A5 (RCJMB04_24l18 · IPI00601320 · Q5F3A5) · ENTREZ:415843⌘
G. gallusUniProtKB:Q5ZIG8 (IPI00601077 · Q5ZIG8 · RCJMB04_26f23) · ENTREZ:428418⌘
G. gallusUniProtKB:Q5ZIT7 (RCJMB04_23k2 · Q5ZIT7 · IPI00601469) · ENTREZ:423182⌘
G. gallusUniProtKB:Q5ZK92 (IPI00599182 · RCJMB04_12e12 · SPAST · Spastin · Q5ZK92 · SPAST_CHICK · IPI00923811 · SPG4) · ENTREZ:421481⌘
G. gallusUniProtKB:Q5ZKX2 (Q5ZKX2 · IPI00820938 · RCJMB04_8n6) · ENTREZ:423586⌘
G. gallusUniProtKB:Q5ZMB8 (RCJMB04_2j13 · IPI00602342 · Q5ZMB8) · ENTREZ:417716⌘
G. gallusUniProtKB:Q5ZMI9 (IPI00582043 · Q5ZMI9 · RCJMB04_1o9) · ENTREZ:420901⌘
G. gallusUniProtKB:Q5ZMU9 (IPI00585183 · RCJMB04_1c3 · Q5ZMU9 · vcp) · ENTREZ:427410⌘
H. sapiensENSEMBL:ENSG00000141385 · UniProtKB:Q9Y4W6 (AFG32_HUMAN · AFG3L2 · Q9Y4W6 · IPI00001091)AFG3-like protein 2⌘
H. sapiensENSEMBL:ENSG00000138138 · UniProtKB:Q8NBU5 (FNP001 · ATAD1_HUMAN · Q8NBU5 · IPI00171445 · ATAD1)ATPase family AAA domain-containing protein 1⌘
H. sapiensENSEMBL:ENSG00000156802 · UniProtKB:Q6PL18 (L16 · ATAD2_HUMAN · ATAD2 · IPI00470801 · IPI00170548 · Q6PL18 · PRO2000)ATPase family AAA domain-containing protein 2⌘
H. sapiensENSEMBL:ENSG00000119778 · UniProtKB:Q9ULI0 (ATD2B_HUMAN · IPI00739581 · ATAD2B · KIAA1240 · IPI00456004 · Q9ULI0)ATPase family AAA domain-containing protein 2B⌘
H. sapiensENSEMBL:ENSG00000132436 · UniProtKB:Q6PIW4 (FIGL1_HUMAN · IPI00335421 · Q6PIW4 · FIGNL1 · IPI00855706)Fidgetin-like protein 1⌘
H. sapiensENSEMBL:ENSG00000205432 · UniProtKB:A6NMB9 (FIGL2_HUMAN · FIGNL2 · A6NMB9 · IPI00783444)Putative fidgetin-like protein 2⌘
H. sapiensENSEMBL:ENSG00000182263 · UniProtKB:Q5HY92 (IPI00164946 · Q5HY92 · Fidgetin · FIGN · FIGN_HUMAN)⌘
H. sapiensENSEMBL:ENSG00000102781 · UniProtKB:Q9BW62 (Q9BW62 · KATNAL1 · IPI00789455 · KATL1_HUMAN)Katanin p60 ATPase-containing subunit A-like 1⌘
H. sapiensENSEMBL:ENSG00000167216 · UniProtKB:Q8IYT4 (KATL2_HUMAN · IPI00239789 · IPI00894474 · KATNAL2 · Q8IYT4)Katanin p60 ATPase-containing subunit A-like 2⌘
H. sapiensENSEMBL:ENSG00000186625 · UniProtKB:O75449 (IPI00013075 · KTNA1_HUMAN · O75449 · IPI00384339 · KATNA1)Katanin p60 ATPase-containing subunit A1⌘
H. sapiensENSEMBL:ENSG00000073969 · UniProtKB:P46459 (IPI00006451 · NSF · NSF_HUMAN · P46459)Vesicle-fusing ATPase⌘
H. sapiensENSEMBL:ENSG00000143748 · UniProtKB:O15381 (IPI00183080 · NVL · IPI00006197 · IPI00185801 · O15381 · NVL_HUMAN)Nuclear valosin-containing protein-like⌘
H. sapiensENSEMBL:ENSG00000127980 · UniProtKB:O43933 (PEX1_HUMAN · O43933 · IPI00411291 · PEX1)Peroxisome biogenesis factor 1⌘
H. sapiensENSEMBL:ENSG00000124587 · UniProtKB:Q13608 (PEX6 · Q13608 · IPI00299182 · PXAAA1 · PEX6_HUMAN)Peroxisome assembly factor 2⌘
H. sapiensENSEMBL:ENSG00000100519 · UniProtKB:P62333 (P62333 · SUG2 · PRS10_HUMAN · IPI00021926 · PSMC6)26S protease regulatory subunit S10B⌘
H. sapiensENSEMBL:ENSG00000100764 · UniProtKB:P62191 (PSMC1 · PRS4_HUMAN · P62191 · IPI00011126)26S protease regulatory subunit 4⌘
H. sapiensENSEMBL:ENSG00000165916 · UniProtKB:P17980 (PRS6A_HUMAN · IPI00018398 · TBP1 · P17980 · PSMC3)26S protease regulatory subunit 6A⌘
H. sapiensENSEMBL:ENSG00000013275 · UniProtKB:P43686 (IPI00020042 · MIP224 · PRS6B_HUMAN · TBP7 · IPI00216770 · PSMC4 · P43686)26S protease regulatory subunit 6B⌘
H. sapiensENSEMBL:ENSG00000161057 · UniProtKB:P35998 (P35998 · PRS7_HUMAN · PSMC2 · IPI00021435 · MSS1)26S protease regulatory subunit 7⌘
H. sapiensENSEMBL:ENSG00000087191 · UniProtKB:P62195 (PSMC5 · SUG1 · PRS8_HUMAN · P62195 · IPI00023919)26S protease regulatory subunit 8⌘
H. sapiensENSEMBL:ENSG00000171763 · UniProtKB:Q9BVQ7 (SPATA5L1 · IPI00890778 · IPI00031608 · Q9BVQ7 · SPA5L_HUMAN · IPI00386906)Spermatogenesis-associated protein 5-like protein 1⌘
H. sapiensENSEMBL:ENSG00000021574 · UniProtKB:Q9UBP0 (SPAST · Spastin · IPI00002707 · KIAA1083 · IPI00219816 · SPAST_HUMAN · SPG4 · Q9UBP0)⌘
H. sapiensENSEMBL:ENSG00000145375 · UniProtKB:Q8NB90 (Q8NB90 · SPAF · IPI00890715 · AFG2 · IPI00329583 · IPI00890727 · SPAT5_HUMAN · SPATA5)Spermatogenesis-associated protein 5⌘
H. sapiensENSEMBL:ENSG00000197912 · UniProtKB:Q9UQ90 (IPI00398508 · Paraplegin · CAR · Q9UQ90 · SPG7 · CMAR · SPG7_HUMAN · PGN · IPI00299010)⌘
H. sapiensENSEMBL:ENSG00000165280 · UniProtKB:P55072 (TERA_HUMAN · P55072 · IPI00022774 · VCP)Transitional endoplasmic reticulum ATPase⌘
H. sapiensENSEMBL:ENSG00000132612 · UniProtKB:Q9UN37 (Q9UN37 · VPS4 · VPS4A_HUMAN · IPI00411356 · VPS4A)Vacuolar protein sorting-associating protein 4A⌘
H. sapiensENSEMBL:ENSG00000119541 · UniProtKB:O75351 (VPS4B · VPS4B_HUMAN · VPS42 · O75351 · IPI00182728 · SKD1)Vacuolar protein sorting-associating protein 4B⌘
H. sapiensENSEMBL:ENSG00000136758 · UniProtKB:Q96TA2 (YME1L · Q96TA2 · YMEL1_HUMAN · FTSH1 · IPI00099529 · YME1L1 · IPI00045946 · UNQ1868/PRO4304)ATP-dependent metalloprotease YME1L1⌘
M. musculusNCBI:XP_001000159 · MGI:MGI:3646919
M. musculusNCBI:NP_001093098 · MGI:MGI:2444798
M. musculusUniProtKB:Q920A7 · MGI:MGI:1928277 (Afg3l1)AFG3(ATPase family gene 3)-like 1 (yeast)⌘
M. musculusUniProtKB:Q8JZQ2 · MGI:MGI:1916847 (Afg3l2 · Emv66 · par)AFG3(ATPase family gene 3)-like 2 (yeast)⌘
M. musculusUniProtKB:Q9D5T0 · MGI:MGI:1915229 (Atad1)ATPase family, AAA domain containing 1⌘
M. musculusUniProtKB:Q8CDM1 · MGI:MGI:1917722 (Atad2)ATPase family, AAA domain containing 2⌘
M. musculusUniProtKB:Q8BPY9 · MGI:MGI:1890648 (Fignl1)fidgetin-like 1⌘
M. musculusMGI:MGI:1890647 (Fign · fidgetin) · UniProtKB:Q9ERZ6⌘
M. musculusUniProtKB:Q8K0T4 · MGI:MGI:2387638 (Katnal1)katanin p60 subunit A-like 1⌘
M. musculusUniProtKB:Q9D3R6 · MGI:MGI:1924234 (Katnal2)katanin p60 subunit A-like 2⌘
M. musculusUniProtKB:Q9WV86 · MGI:MGI:1344353 (Katna1)katanin p60 (ATPase-containing) subunit A1⌘
M. musculusUniProtKB:P46460 · MGI:MGI:104560 (SKD2 · Nsf)N-ethylmaleimide sensitive factor · N-ethylmaleimide sensitive fusion protein⌘
M. musculusUniProtKB:Q9DBY8 · MGI:MGI:1914709 (Nvl)nuclear VCP-like⌘
M. musculusUniProtKB:Q5BL07 · MGI:MGI:1918632 (Pex1 · ZWS1)peroxisome biogenesis factor 1 · peroxisomal biogenesis factor 1⌘
M. musculusUniProtKB:Q99LC9 · MGI:MGI:2385054 (Pex6)peroxisomal biogenesis factor 6⌘
M. musculusUniProtKB:P62334 · MGI:MGI:1914339 (Psmc6)proteasome (prosome, macropain) 26S subunit, ATPase, 6⌘
M. musculusUniProtKB:P62192 · MGI:MGI:106054 (Psmc1 · S4 · P26s4)protease (prosome, macropain) 26S subunit, ATPase 1⌘
M. musculusUniProtKB:O88685 · MGI:MGI:1098754 (Psmc3 · TBP-1)Tat binding protein 1 · proteasome (prosome, macropain) 26S subunit, ATPase 3⌘
M. musculusUniProtKB:P54775 · MGI:MGI:1346093 (MIP224 · Psmc4 · CIP21)proteasome (prosome, macropain) 26S subunit, ATPase, 4 · CAR interacting protein 21⌘
M. musculusUniProtKB:P46471 · MGI:MGI:109555 (Psmc2)proteasome (prosome, macropain) 26S subunit, ATPase 2⌘
M. musculusUniProtKB:P62196 · MGI:MGI:105047 (Psmc5 · mSUG1)protease (prosome, macropain) 26S subunit, ATPase 5⌘
M. musculusMGI:MGI:1858896 (Spg4 · spastin · Spast) · UniProtKB:Q9QYY8⌘
M. musculusUniProtKB:Q3UMC0 · MGI:MGI:1927170 (Spata5 · Spaf · C78064)spermatogenesis associated 5⌘
M. musculusUniProtKB:Q3ULF4 · MGI:MGI:2385906 (paraplegin · Spg7 · Cmar)spastic paraplegia 7 homolog (human)⌘
M. musculusUniProtKB:Q01853 · MGI:MGI:99919 (p97 · CDC48 · Vcp · p97/VCP)valosin containing protein · AAA ATPase p97⌘
M. musculusUniProtKB:Q8VEJ9 · MGI:MGI:1890520 (Vps4a)vacuolar protein sorting 4a (yeast)⌘
M. musculusUniProtKB:P46467 · MGI:MGI:1100499 (Skd1 · Vps4b)vacuolar protein sorting 4b (yeast)⌘
M. musculusUniProtKB:O88967 · MGI:MGI:1351651 (Ftsh · Yme1l1)YME1-like 1 (S. cerevisiae) · ATP-dependent metalloprotease FtsH1⌘
M. musculusUniProtKB:Q3TER3 · MGI:MGI:3036261 (Spata5l1)spermatogenesis associated 5-like 1⌘
R. norvegicusNCBI:XP_235326 · RGD:1304849 (Atad2)ATPase family, AAA domain containing 2⌘
R. norvegicusNCBI:XP_001065624 · RGD:1566321 (Fignl2)fidgetin-like 2⌘
R. norvegicusNCBI:XP_342236 · RGD:1310478
R. norvegicusNCBI:XP_001073066 · RGD:1595990 (LOC691729)similar to spermatogenesis associated 5-like 1⌘
R. norvegicusNCBI:XP_213963 · RGD:1311270
R. norvegicusNCBI:XP_001065741 · RGD:1308494 (spastin · Spast)⌘
R. norvegicusNCBI:XP_229979 · RGD:1308174 (Fign · fidgetin)⌘
R. norvegicusNCBI:XP_341715 · RGD:1309722 (Afg3l1)AFG3(ATPase family gene 3)-like 1 (S. cerevisiae)⌘
R. norvegicusNCBI:XP_001068563 · RGD:1559939 (Pex1)peroxisome biogenesis factor 1⌘
R. norvegicusRGD:1308570 (Atad1) · UniProtKB:Q505J9 (IPI00566676 · ATAD1_RAT · Atad1 · Q505J9)ATPase family, AAA domain containing 1 · ATPase family AAA domain-containing protein 1⌘⌘
R. norvegicusUniProtKB:Q6GX84 · RGD:1307112 (Fignl1)fidgetin-like 1⌘
R. norvegicusUniProtKB:Q5XIK7 · RGD:1359252 (Katnal1)katanin p60 subunit A-like 1⌘
R. norvegicusUniProtKB:Q6E0V2 · RGD:1303062 (Katna1)katanin p60 (ATPase-containing) subunit A1⌘
R. norvegicusUniProtKB:Q9QUL6 · RGD:621594 (Nsf)N-ethylmaleimide-sensitive factor⌘
R. norvegicusUniProtKB:P54777 · RGD:621637 (Pex6)peroxisomal biogenesis factor 6⌘
R. norvegicusUniProtKB:P62193 · RGD:621097 (Psmc1)proteasome (prosome, macropain) 26S subunit, ATPase, 1⌘
R. norvegicusUniProtKB:Q63569 · RGD:61905 (Psmc3)proteasome (prosome, macropain) 26S subunit, ATPase 3⌘
R. norvegicusUniProtKB:Q63570 · RGD:621102 (Psmc4)proteasome (prosome, macropain) 26S subunit, ATPase, 4⌘
R. norvegicusUniProtKB:Q63347 · RGD:3428 (Psmc2)proteasome (prosome, macropain) 26S subunit, ATPase 2⌘
R. norvegicusUniProtKB:P62198 · RGD:708376 (Psmc5)proteasome (prosome, macropain) 26S subunit, ATPase, 5⌘
R. norvegicusUniProtKB:Q7TT47 · RGD:727940 (Spg7)spastic paraplegia 7 homolog (human)⌘
R. norvegicusUniProtKB:P46462 · RGD:621595 (Vcp)valosin-containing protein⌘
R. norvegicusRGD:628810 (Vps4a) · UniProtKB:Q793F9 (VPS4A_RAT · vps4-A · Q793F9 · IPI00204016 · Vps4a)vacuolar protein sorting 4 homolog A (S. cerevisiae) · Vacuolar protein sorting-associated protein 4A⌘⌘
R. norvegicusRGD:620764 (Yme1l1) · UniProtKB:Q925S8 (YMEL1_RAT · Q925S8 · IPI00206065 · Yme1l1)YME1-like 1 (S. cerevisiae) · ATP-dependent metalloprotease YME1L1⌘⌘
R. norvegicusUniProtKB:Q32PW9 · RGD:1308825 (Psmc6)proteasome (prosome, macropain) 26S subunit, ATPase, 6⌘
R. norvegicusUniProtKB:Q4KLL7 · RGD:1305969 (Vps4b)vacuolar protein sorting 4 homolog B (S. cerevisiae)⌘
S. cerevisiaeUniProtKB:P32794 · SGD:S000004389 (YLR397C · AFG2 · DRG1)ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex⌘
S. cerevisiaeUniProtKB:P39925 · SGD:S000000819 (YER017C · AFG3 · YTA10)Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes⌘
S. cerevisiaeUniProtKB:P25694 · SGD:S000002284 (CDC48 · YDL126C)ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97⌘
S. cerevisiaeUniProtKB:P28737 · SGD:S000003260 (YGR028W · YTA4 · MSP1)Mitochondrial protein involved in sorting of proteins in the mitochondria⌘
S. cerevisiaeUniProtKB:P24004 · SGD:S000001680 (YKL197C · PEX1 · PAS1)AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol⌘
S. cerevisiaeUniProtKB:P33760 · SGD:S000005273 (PEX6 · PAS8 · YNL329C)AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol⌘
S. cerevisiaeUniProtKB:P53549 · SGD:S000005785 (PCS1 · SUG2 · YOR259C · CRL13 · RPT4)One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates⌘
S. cerevisiaeUniProtKB:P40327 · SGD:S000002165 (YDL007W · RPT2 · YHS4 · YTA5)One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates⌘
S. cerevisiaeUniProtKB:P33297 · SGD:S000005643 (RPT5 · YTA1 · YOR117W)One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates⌘
S. cerevisiaeUniProtKB:P33298 · SGD:S000002802 (YTA2 · RPT3 · YNT1 · YDR394W)One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates⌘
S. cerevisiaeUniProtKB:P33299 · SGD:S000001628 (YKL145W · CIM5 · RPT1 · YTA3)One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates⌘
S. cerevisiaeUniProtKB:Q01939 · SGD:S000003016 (SUG1 · CIM3 · CRL3 · YGL048C · RPT6 · SCB68)One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates⌘
S. cerevisiaeUniProtKB:P40341 · SGD:S000004695 (RCA1 · YTA12 · YMR089C)Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes⌘
S. cerevisiaeUniProtKB:Q07844 · SGD:S000003957 (YLL034C · RIX7)Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus⌘
S. cerevisiaeUniProtKB:P39955 · SGD:S000000849 (YER047C · SAP1)Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system⌘
S. cerevisiaeUniProtKB:P18759 · SGD:S000000284 (SEC18 · YBR080C · ANU4)ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport⌘
S. cerevisiaeUniProtKB:P40328 · SGD:S000005995 (YPL074W · YTA6)Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells⌘
S. cerevisiaeUniProtKB:P40340 · SGD:S000003502 (YTA7 · YGR270W)Protein that localizes to chromatin and has a role in regulation of histone gene expression⌘
S. cerevisiaeUniProtKB:P52917 · SGD:S000006377 (YPR173C · VPT10 · VPL4 · END13 · DID6 · CSC1 · GRD13 · VPS4)AAA-ATPase involved in multivesicular body (MVB) protein sorting, ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release⌘
S. cerevisiaeUniProtKB:P32795 · SGD:S000006228 (OSD1 · YME1 · YTA11 · YPR024W)Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products⌘
S. pombeUniProtKB:O60058 · GeneDB_Spombe:SPBC56F2.07c (SPBC56F2.07c)ribosome biogenesis factor recycling AAA family ATPase⌘
S. pombeUniProtKB:Q9P3A7 · GeneDB_Spombe:SPAC1565.08 (SPAC6F12.01 · SPAC1565.08 · cdc48)AAA family ATPase Cdc48⌘
S. pombeGeneDB_Spombe:SPAC17A5.01 (SPAC17A5.01 · pex6 · peroxin-6) · UniProtKB:O13764⌘
S. pombeUniProtKB:O74445 · GeneDB_Spombe:SPCC1682.16 (rpt4 · SPCC1682.16)19S proteasome regulatory subunit Rpt4⌘
S. pombeUniProtKB:P36612 · GeneDB_Spombe:SPBC4.07c (SPBC4.07c · rpt2 · mts2)19S proteasome regulatory subunit Rpt2⌘
S. pombeUniProtKB:O14126 · GeneDB_Spombe:SPAC3A11.12c (SPAC3A11.12c · pam2 · rpt5 · tbp1)19S proteasome regulatory subunit Rpt5⌘
S. pombeUniProtKB:O74894 · GeneDB_Spombe:SPCC576.10c (SPCC576.10c · rpt3)19S proteasome regulatory subunit Rpt3⌘
S. pombeUniProtKB:O42931 · GeneDB_Spombe:SPBC16C6.07c (SPBC16C6.07c · rpt1)19S proteasome regulatory subunit Rpt1⌘
S. pombeUniProtKB:P41836 · GeneDB_Spombe:SPBC23G7.12c (SPBC23G7.12c · rpt6 · let1)19S proteasome regulatory subunit Rpt6⌘
S. pombeUniProtKB:Q9HGM3 · GeneDB_Spombe:SPBC543.09 (SPBC543.09)mitochondrial m-AAA protease⌘
S. pombeUniProtKB:Q9P7Q4 · GeneDB_Spombe:SPAC1834.11c (sec18 · SPAC1834.11c)secretory pathway protein Sec18⌘
S. pombeUniProtKB:O43078 · GeneDB_Spombe:SPBC947.01 (SPBC947.01)AAA family ATPase, unknown biological role⌘
S. pombeUniProtKB:Q09803 · GeneDB_Spombe:SPAC2G11.06 (vps4 · SPAC2G11.06)AAA family ATPase Vps4⌘
S. pombeUniProtKB:O14325 · GeneDB_Spombe:SPBC16E9.10c (SPBC16E9.10c)AAA family ATPase Rix7⌘
S. pombeUniProtKB:O14114 · GeneDB_Spombe:SPAC31G5.19 (SPAC31G5.19)ATPase with bromodomain protein⌘
S. pombeUniProtKB:Q9C0W2 · GeneDB_Spombe:SPBP22H7.05c (SPBP22H7.05c)ATPase with bromodomain protein⌘
S. pombeUniProtKB:Q9P7J5 · GeneDB_Spombe:SPCC24B10.10c (SPCC24B10.10c)mitochondrial outer membrane ATPase Msp1⌘
S. pombeUniProtKB:O59824 · GeneDB_Spombe:SPCC965.04c (SPCC965.04c)mitochondrial inner membrane i-AAA protease complex subunit Yme1⌘
S. pombeUniProtKB:O74941 · GeneDB_Spombe:SPCC553.03 (pex1 · SPCC553.03)AAA family ATPase Pex1⌘
S. pombeUniProtKB:Q9P3U2 · GeneDB_Spombe:SPAC328.04 (SPAC328.04)AAA family ATPase, unknown biological role⌘
ProteinPublicationCurator Notes
UniProtKB:P39925 · SGD:S000000819PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein Q9Y4W6 complements a homologous mutation in S. cerevisiae. Expression of human AFG3L2, in conjunction with paraplegin, complements a yeast afg3 yta12 double mutant; both human genes are required.
UniProtKB:P40341 · SGD:S000004695PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein Q9Y4W6 complements a homologous mutation in S. cerevisiae. Expression of human AFG3L2, in conjunction with paraplegin, complements a yeast afg3 yta12 double mutant; both human genes are required.
UniProtKB:P39925 · SGD:S000000819PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein Q9UQ90 complements a homologous mutation in S. cerevisiae. Expression of human paraplegin, in conjunction with AFG3L2, complements a yeast afg3 yta12 double mutant; both human genes are required.
UniProtKB:P40341 · SGD:S000004695PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein Q9UQ90 complements a homologous mutation in S. cerevisiae. Expression of human paraplegin, in conjunction with AFG3L2, complements a yeast afg3 yta12 double mutant; both human genes are required.
UniProtKB:P33299 · SGD:S000001628PMID:10417703 Fu H, et al. Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome. Plant J. 1999 Jun;18(5):529-39.The A. thaliana protein AT1G53750.1 complements a homologous mutation in S. cerevisiae. AT1G53750.1 is the Arabidopsis RPT1a subunit, whereas AT1G53780.1 is similar to the RPT1a subunit.
UniProtKB:P33297 · SGD:S000005643PMID:10417703 Fu H, et al. Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome. Plant J. 1999 Jun;18(5):529-39.The A. thaliana protein AT3G05530.1 complements a homologous mutation in S. cerevisiae. AT3G05530.1 is the Arabidopsis RPT5a subunit, whereas AT1G09100.1 is similar to the RPT5a subunit.
UniProtKB:P25694 · SGD:S000002284PMID:8521820 Feiler HS, et al. The higher plant Arabidopsis thaliana encodes a functional CDC48 homologue which is highly expressed in dividing and expanding cells. EMBO J. 1995 Nov 15;14(22):5626-37.The A. thaliana protein AT3G09840.1 complements a homologous mutation in S. cerevisiae.
UniProtKB:Q01939 · SGD:S000003016PMID:10417703 Fu H, et al. Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome. Plant J. 1999 Jun;18(5):529-39.The A. thaliana protein AT5G19990.1 complements a homologous mutation in S. cerevisiae. AT5G19990.1 is the Arabidopsis RPT6a subunit, whereas AT5G20000.1 is almost identical to the RPT6a subunit.
UniProtKB:P53549 · SGD:S000005785PMID:10417703 Fu H, et al. Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome. Plant J. 1999 Jun;18(5):529-39.The A. thaliana protein AT5G43010.1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P33298 · SGD:S000002802PMID:10417703 Fu H, et al. Structural and functional analysis of the six regulatory particle triple-A ATPase subunits from the Arabidopsis 26S proteasome. Plant J. 1999 Jun;18(5):529-39.The A. thaliana protein AT5G58290.1 complements a homologous mutation in S. cerevisiae.
UniProtKB:Q01939 · SGD:S000003016PMID:9469929 Mounkes LC, et al. The DUG gene of Drosophila melanogaster encodes a structural and functional homolog of the S. cerevisiae SUG1 predicted ATPase associated with the 26S proteasome. Gene. 1998 Jan 12;206(2):165-74.The D. melanogaster protein CG1489-PA complements a homologous mutation in S. cerevisiae.
UniProtKB:P33297 · SGD:S000005643PMID:7754704 Schnall R, et al. Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex. Yeast. 1994 Sep;10(9):1141-55.The H. sapiens protein P17980 complements a homologous mutation in S. cerevisiae.
UniProtKB:Q01939 · SGD:S000003016PMID:7870181 Lee JW, et al. Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature. 1995 Mar 2;374(6517):91-4.The H. sapiens protein P62195 complements a homologous mutation in S. cerevisiae. P62195 is referred to as PSMC5 and also TRIP1.
UniProtKB:Q01939 · SGD:S000003016PMID:8710853 Wang W, et al. Mammalian Sug1 and c-Fos in the nuclear 26S proteasome. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8236-40.The M. musculus protein P62196 complements a homologous mutation in S. cerevisiae.
UniProtKB:P39925 · SGD:S000000819PMID:12228240 Kolodziejczak M, et al. A higher plant mitochondrial homologue of the yeast m-AAA protease. Molecular cloning, localization, and putative function. J Biol Chem. 2002 Nov 15;277(46):43792-8.The P. sativum protein PsFtsH complements a homologous mutation in S. cerevisiae. P. sativum PsFtsH complements a yeast yta10 null mutant and a yta10 yta12 double mutant.
UniProtKB:P40341 · SGD:S000004695PMID:12228240 Kolodziejczak M, et al. A higher plant mitochondrial homologue of the yeast m-AAA protease. Molecular cloning, localization, and putative function. J Biol Chem. 2002 Nov 15;277(46):43792-8.The P. sativum protein PsFtsH complements a homologous mutation in S. cerevisiae. P. sativum PsFtsH complements a yeast yta12 null mutant and a yta10 yta12 double mutant.
UniProtKB:P39925 · SGD:S000000819PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein SPG7 complements a homologous mutation in S. cerevisiae.
UniProtKB:P40341 · SGD:S000004695PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein SPG7 complements a homologous mutation in S. cerevisiae.
UniProtKB:P39925 · SGD:S000000819PMID:20208537 Di Bella D, et al. Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet. 2010 Apr;42(4):313-21.The H. sapiens protein AFG3L2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P39925 · SGD:S000000819PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein AFG3L2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P40341 · SGD:S000004695PMID:20208537 Di Bella D, et al. Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet. 2010 Apr;42(4):313-21.The H. sapiens protein AFG3L2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P40341 · SGD:S000004695PMID:14623864 Atorino L, et al. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol. 2003 Nov 24;163(4):777-87.The H. sapiens protein AFG3L2 complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (10)
ENSEMBL:ENSG00000127980 · UniProtKB:O43933#202370 ADRENOLEUKODYSTROPHY, AUTOSOMAL NEONATAL FORM;;NEONATAL ADRENOLEUKODYSTROPHY; NALD
ENSEMBL:ENSG00000124587 · UniProtKB:Q13608+602136 PEROXISOME BIOGENESIS FACTOR 1; PEX1;;PEROXIN 1PEROXISOME BIOGENESIS DISORDER, COMPLEMENTATION GROUP 1, INCLUDED;;PEROXISOME BIOGENESIS DISORDER, COMPLEMENTATION GROUP E, INCLUDED
#601539 PEROXISOME BIOGENESIS DISORDERS; PBD
#266510 REFSUM DISEASE, INFANTILE FORM;;IRD;;INFANTILE PHYTANIC ACID STORAGE DISEASE
ENSEMBL:ENSG00000021574 · UniProtKB:Q9UBP0#601539 PEROXISOME BIOGENESIS DISORDERS; PBD
+601498 PEROXISOME BIOGENESIS FACTOR 6; PEX6;;PEROXIN 6;;PEROXISOMAL ASSEMBLY FACTOR 2; PAF2;;PEROXISOMAL-TYPE ATPase 1; PXAAA1PEROXISOME BIOGENESIS DISORDER, COMPLEMENTATION GROUP 4, INCLUDED;;PEROXISOME BIOGENESIS DISORDER, COMPLEMENTATION GROUP 6, INCLUDED;;PEROXISOME BIOGENESIS DISORDER, COMPLEMENTATION GROUP C, INCLUDED
#214100 ZELLWEGER SYNDROME; ZS;;CEREBROHEPATORENAL SYNDROME;;CHR SYNDROME;;ZWS
ENSEMBL:ENSG00000197912 · UniProtKB:Q9UQ90#182601 SPASTIC PARAPLEGIA 4, AUTOSOMAL DOMINANT; SPG4;;FAMILIAL SPASTIC PARAPLEGIA, AUTOSOMAL DOMINANT, 2; FSP2
ENSEMBL:ENSG00000165280 · UniProtKB:P55072#607259 SPASTIC PARAPLEGIA 7, AUTOSOMAL RECESSIVE; SPG7
UniProtKB:P39925 · SGD:S000000819#167320 INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE AND FRONTOTEMPORALDEMENTIA; IBMPFD;;MUSCULAR DYSTROPHY, LIMB-GIRDLE, WITH PAGET DISEASE OF BONE;;PAGETOID AMYOTROPHIC LATERAL SCLEROSIS;;PAGETOID NEUROSKELETAL SYNDROME;;LOWER MOTOR NEURON DEGENERATION WITH PAGET-LIKE BONE DISEASE
SGD Disease Papers (19)
UniProtKB:P25694 · SGD:S000002284PMID:9635427 Casari G, et al. (1998) Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Cell 93(6):973-83
PMID:14623864 Atorino L, et al. (2003) Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol 163(4):777-87
UniProtKB:P24004 · SGD:S000001680PMID:16822868 Braun RJ, et al. (2006) Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast. J Biol Chem 281(35):25757-67
UniProtKB:P33760 · SGD:S000005273PMID:9398847 Reuber BE, et al. (1997) Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders. Nat Genet 17(4):445-8
PMID:15168551 Fujiki Y (2004) [Peroxisome biogenesis and human peroxisomal disorders] Tanpakushitsu Kakusan Koso 49(7 Suppl):1136-42
PMID:10904262 Gould SJ and Valle D (2000) Peroxisome biogenesis disorders: genetics and cell biology. Trends Genet 16(8):340-5
PMID:10212151 Chang CC, et al. (1999) Metabolic control of peroxisome abundance. J Cell Sci 112 ( Pt 10):1579-90
UniProtKB:Q01939 · SGD:S000003016PMID:9480815 Shimozawa N, et al. (1998) Peroxisome biogenesis disorders: identification of a new complementation group distinct from peroxisome-deficient CHO mutants and not complemented by human PEX 13. Biochem Biophys Res Commun 243(2):368-71
PMID:8940266 Fukuda S, et al. (1996) Human peroxisome assembly factor-2 (PAF-2): a gene responsible for group C peroxisome biogenesis disorder in humans. Am J Hum Genet 59(6):1210-20
PMID:8670792 Yahraus T, et al. (1996) The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor. EMBO J 15(12):2914-23
PMID:7544797 Slawecki ML, et al. (1995) Identification of three distinct peroxisomal protein import defects in patients with peroxisome biogenesis disorders. J Cell Sci 108 ( Pt 5):1817-29
PMID:10904262 Gould SJ and Valle D (2000) Peroxisome biogenesis disorders: genetics and cell biology. Trends Genet 16(8):340-5
PMID:10212151 Chang CC, et al. (1999) Metabolic control of peroxisome abundance. J Cell Sci 112 ( Pt 10):1579-90
UniProtKB:P40341 · SGD:S000004695PMID:9173976 Weeda G, et al. (1997) The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor. Nucleic Acids Res 25(12):2274-83
UniProtKB:P52917 · SGD:S000006377PMID:9635427 Casari G, et al. (1998) Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Cell 93(6):973-83
PMID:14623864 Atorino L, et al. (2003) Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol 163(4):777-87
PMID:12134146 Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
UniProtKB:P32795 · SGD:S000006228PMID:14617349 Khor R, et al. (2003) The ubiquitin-vacuolar protein sorting system is selectively required during entry of influenza virus into host cells. Traffic 4(12):857-68
UniProtKB:P32795 · SGD:S000006228PMID:9635427 Casari G, et al. (1998) Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Cell 93(6):973-83
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu