P-POD: Princeton Protein Orthology Database: GO3/Jaccard38

This family has 316 members: 79 Arabidopsis thaliana, 27 Caenorhabditis elegans, 25 Danio rerio, 16 Dictyostelium discoideum, 23 Drosophila melanogaster, 8 Escherichia coli, 24 Gallus gallus, 27 Homo sapiens, 26 Mus musculus, 34 Rattus norvegicus, 15 Saccharomyces cerevisiae, 12 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Jaccard38
316 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_193301.1 · TAIR:locus:2130544 (DL3870W · AT4G15660 · FCAALL.353)⌘
A. thalianaNCBI:NP_188232.2 · TAIR:locus:2093447 (AT3G16110 · ATPDI4 · ATPDIL1-6 · PDI4 · MSL1.15)ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 4 · PROTEIN DISULFIDE ISOMERASE 4 · PDI-LIKE 1-6⌘
A. thalianaNCBI:NP_173403.1 · TAIR:locus:2013169 (F14P1.32 · F14P1_32 · AT1G19730 · thioredoxin · ATH4 · ATTRX4)thioredoxin H-type 4⌘
A. thalianaNCBI:NP_191201.1 · TAIR:locus:2102579 (T5P19.70 · AT3G56420)⌘
A. thalianaNCBI:NP_181611.2 · TAIR:locus:2064854 (ATCXXS2 · T7D17_3 · AT2G40790 · T7D17.3)C-TERMINAL CYSTEINE RESIDUE IS CHANGED TO A SERINE 1⌘
A. thalianaNCBI:NP_191855.1 · TAIR:locus:2099197
A. thalianaNCBI:NP_190672.1 · TAIR:locus:2080963 (AT3G51030 · F24M12.70 · thioredoxin · ATTRX1)Attrx h1 · Arabidopsis thaliana thioredoxin H-type 1⌘
A. thalianaNCBI:NP_179159.1 · TAIR:locus:2053573 (ATHM3 · ATM3 · F9O13.12 · AT2G15570)Arabidopsis thioredoxin M-type 3⌘
A. thalianaNCBI:NP_191026.1 · TAIR:locus:2102410 (GR · EMB2360 · T5N23.20 · AT3G54660 · ATGR2)GLUTATHIONE REDUCTASE⌘
A. thalianaNCBI:NP_186922.1 · TAIR:locus:2075522 (TRXF1 · ATF1 · F13E7.33 · F13E7_33 · AT3G02730)THIOREDOXIN F-TYPE 1⌘
A. thalianaNCBI:NP_177802.2 · TAIR:locus:2030051
A. thalianaNCBI:NP_186849.1 · TAIR:locus:2078663 (F1C9.22 · ROXY1 · AT3G02000)⌘
A. thalianaNCBI:NP_182309.1 · TAIR:locus:2043423 (AT2G47880 · T9J23.13)⌘
A. thalianaNCBI:NP_171801.1 · TAIR:locus:2007554 (F10O3_16 · AT1G03020 · F10O3.16)⌘
A. thalianaNCBI:NP_188415.2 · TAIR:locus:2088560 (AT3G17870 · HIP · AT3G17880 · ATHIP2 · MEB5.24 · ATTDX)TETRATICOPEPTIDE DOMAIN-CONTAINING THIOREDOXIN · ARABIDOPSIS THALIANA HSP70-INTERACTING PROTEIN 2 · HSC-70 INTERACTING PROTEIN⌘
A. thalianaNCBI:NP_175636.2 · TAIR:locus:2018134 (F19K6_17 · F19K6.17 · PDI3 · ATPDI3 · ATPDIL1-5 · AT1G52260)PROTEIN DISULFIDE ISOMERASE 3 · ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 3 · PDI-LIKE 1-5⌘
A. thalianaNCBI:NP_192404.1 · TAIR:locus:2135363
A. thalianaNCBI:NP_849585.1 · TAIR:locus:2020813 (ATHM1 · ATM1 · TRX-M1 · AT1G03680)ARABIDOPSIS THIOREDOXIN M-TYPE 1 · THIOREDOXIN M-TYPE 1⌘
A. thalianaNCBI:NP_197144.1 · TAIR:locus:2171322 (AT5G16400 · MQK4.13 · MQK4_13 · TRXF2 · ATF2)THIOREDOXIN F2⌘
A. thalianaNCBI:NP_973787.1 · TAIR:locus:2205145
A. thalianaNCBI:NP_198811.1 · TAIR:locus:2178007 (ATTRX2 · MYH19_110 · ATTRXH2 · TRXH2 · MYH19.110 · ATH2 · AT5G39950 · THIOREDOXIN)THIOREDOXIN H2 · Arabidopsis thioredoxin h2 · THIOREDOXIN 2⌘
A. thalianaNCBI:NP_187483.1 · TAIR:locus:2077833 (ATH9 · AT3G08710 · F17O14.18)thioredoxin H-type 9⌘
A. thalianaNCBI:NP_177146.1 · TAIR:locus:2196784 (AT1G69880 · ATH8 · T17F3_9 · T17F3.9)thioredoxin H-type 8⌘
A. thalianaNCBI:NP_188155.1 · TAIR:locus:2090126 (MJK13.20 · ATHM4 · TRX-M4 · AT3G15360 · ATM4)ARABIDOPSIS THIOREDOXIN M-TYPE 4⌘
A. thalianaNCBI:NP_180851.1 · TAIR:locus:2059395 (AT2G32920 · T21L14_14 · ATPDI9 · T21L14.14 · PDI9 · ATPDIL2-3)ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 9 · PROTEIN DISULFIDE ISOMERASE 9 · PDI-LIKE 2-3⌘
A. thalianaNCBI:NP_851234.1 · TAIR:locus:2175811 (MUP24.6 · AT5G60640 · PDI2 · ATPDIL1-4 · ATPDI2 · MUP24_6)PROTEIN DISULFIDE ISOMERASE 2 · PDI-LIKE 1-4 · ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 2⌘
A. thalianaNCBI:NP_175128.1 · TAIR:locus:2825451 (F27F5.21 · LIV1 · ATH5 · ATTRX5 · AT1G45145 · F27F5_21 · thioredoxin)LOCUS OF INSENSITIVITY TO VICTORIN 1 · thioredoxin H-type 5⌘
A. thalianaNCBI:NP_001078165.1 · TAIR:locus:2086177 (LPD1 · ptlpd1 · K14A17.6 · AT3G16950)LIPOAMIDE DEHYDROGENASE · LIPOAMIDE DEHYDROGENASE 1⌘
A. thalianaNCBI:NP_194346.1 · TAIR:locus:2120860 (AT4G26160 · F20B18_270 · ACHT1 · F20B18.270)ATYPICAL CYS HIS RICH THIOREDOXIN 1⌘
A. thalianaNCBI:NP_175237.1 · TAIR:locus:2023782 (T2J15.6 · mtLPD1 · AT1G48030)mitochondrial lipoamide dehydrogenase 1⌘
A. thalianaNCBI:NP_175021.2 · TAIR:locus:2194661
A. thalianaNCBI:NP_194984.1 · TAIR:locus:2125627 (AT4G32580 · F4D11.220 · F4D11_220)⌘
A. thalianaNCBI:NP_196754.2 · TAIR:locus:2143004
A. thalianaNCBI:NP_191854.1 · TAIR:locus:2099182
A. thalianaNCBI:NP_172620.1 · TAIR:locus:2200141 (ATCXXS1 · AT1G11530 · T23J18_19 · T23J18.19)C-terminal cysteine residue is changed to a serine 1⌘
A. thalianaNCBI:NP_172168.1 · TAIR:locus:2033148
A. thalianaNCBI:NP_191050.1 · TAIR:locus:2082647 (GLUTAREDOXIN · ATGRXCP · AT3G54900 · CXIP1 · F28P10.120)CAX INTERACTING PROTEIN 1⌘
A. thalianaNCBI:NP_180885.1 · TAIR:locus:2051048 (F4P9_4 · F4P9.4 · AT2G33270 · ACHT3)ATYPICAL CYS HIS RICH THIOREDOXIN 3⌘
A. thalianaNCBI:NP_566982.1 · TAIR:locus:2102043 (AT3G53220 · T4D2.150)⌘
A. thalianaNCBI:NP_001078198.1 · TAIR:locus:2089468
A. thalianaNCBI:NP_193305.1 · TAIR:locus:2130574 (DL3890W · FCAALL.358 · AT4G15700)⌘
A. thalianaNCBI:NP_564566.1 · TAIR:locus:2011932 (F14I3_8 · F14I3.8 · ATX · ATHX · AT1G50320)thioredoxin x⌘
A. thalianaNCBI:NP_179617.1 · TAIR:locus:2038932 (F11A3.18 · F11A3_18 · AT2G20270)⌘
A. thalianaNCBI:NP_566522.1 · TAIR:locus:2093297 (ATGRX4 · GRX4 · AT3G15660 · MSJ11.6)A. THALIANA GLUTAREDOXIN 4 · GLUTAREDOXIN 4⌘
A. thalianaNCBI:NP_193303.1 · TAIR:locus:2130564 (FCAALL.384 · DL3880W · AT4G15680)⌘
A. thalianaNCBI:NP_199112.1 · TAIR:locus:2159971 (ATH3 · AT5G42980 · MBD2.18 · ATTRX3 · TRXH3 · MBD2_18 · ATTRXH3 · THIOREDOXIN)THIOREDOXIN H3 · THIOREDOXIN 3 · thioredoxin H-type 3⌘
A. thalianaNCBI:NP_192261.1 · TAIR:locus:2128756 (F9H3_15 · F9H3.15 · ATHM2 · T5L23.1 · AT4G03520)⌘
A. thalianaNCBI:NP_567487.1 · TAIR:locus:505006477 (AT4G16155)⌘
A. thalianaNCBI:NP_565885.1 · TAIR:locus:2042887 (F16M14_20 · GLUTAREDOXIN · CXIP2 · AT2G38270 · ATGRX2 · F16M14.20)CAX-INTERACTING PROTEIN 2⌘
A. thalianaNCBI:NP_195030.1 · TAIR:locus:2123807 (AT4G33040 · F4I10.5)⌘
A. thalianaNCBI:NP_193304.1 · TAIR:locus:2130569 (DL3885W · AT4G15690 · FCAALL.357)⌘
A. thalianaNCBI:NP_849469.1 · TAIR:locus:2134443 (T16L4_180 · ACHT2 · T16L4.180 · AT4G29670)ATYPICAL CYS HIS RICH THIOREDOXIN 2⌘
A. thalianaNCBI:NP_564462.1 · TAIR:locus:2014681 (F15O4.20 · ATPDI8 · PDI8 · ATPDIL5-2 · AT1G35620)PROTEIN DISULFIDE ISOMERASE 8 · ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 8 · PDI-LIKE 5-2⌘
A. thalianaNCBI:NP_177875.1 · TAIR:locus:2204670 (ATPDI6 · T5M16_10 · AT1G77510 · T5M16.10 · PDI6 · ATPDIL1-2)PROTEIN DISULFIDE ISOMERASE 6 · PDI-LIKE 1-2⌘
A. thalianaNCBI:NP_176182.1 · TAIR:locus:2025971 (F23H11_5 · F23H11.5 · AT1G59730 · ATH7)thioredoxin H-type 7⌘
A. thalianaNCBI:NP_171990.3 · TAIR:locus:2010577 (F13M7.3 · PDI10 · AT1G04980 · F13M7_3 · ATPDI10 · ATPDIL2-2)PDI-LIKE 2-2 · PROTEIN DISULFIDE ISOMERASE · ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 10⌘
A. thalianaNCBI:NP_180612.1 · TAIR:locus:2064327
A. thalianaNCBI:NP_181046.1 · TAIR:locus:2044772
A. thalianaNCBI:NP_177861.1 · TAIR:locus:2031452 (F2P24_8 · F2P24.8 · AT1G77370)⌘
A. thalianaNCBI:NP_172333.1 · TAIR:locus:2025625 (F22O13_5 · ACHT4 · AT1G08570 · F22O13.5)ATYPICAL CYS HIS RICH THIOREDOXIN 4⌘
A. thalianaNCBI:NP_564371.1 · TAIR:locus:2015736
A. thalianaNCBI:NP_568962.1 · TAIR:locus:2166325 (MJH22_9 · MJH22.9 · AT5G63030)⌘
A. thalianaNCBI:NP_197550.1 · TAIR:locus:2149942 (F7C8_90 · AT5G20500 · F7C8.90)⌘
A. thalianaNCBI:NP_191056.2 · TAIR:locus:2082712 (ATPDIL1-3 · ATPDI1 · AT3G54960 · PDI1 · T15C9.4)PDI-LIKE 1-3 · ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 1 · PROTEIN DISULFIDE ISOMERASE 1⌘
A. thalianaNCBI:NP_849586.1 · TAIR:locus:2024162 (F21M11.22 · F21M11_22 · AT1G03850)⌘
A. thalianaNCBI:NP_851005.1 · TAIR:locus:2089030 (MGD8.7 · AT3G17240 · mtLPD2)LIPOAMIDE DEHYDROGENASE 2⌘
A. thalianaNCBI:NP_001119339.1 · TAIR:locus:2170593 (MPO12_80 · AT5G40370 · MPO12.80)⌘
A. thalianaNCBI:NP_189059.1 · TAIR:locus:2093691 (MUJ8_3 · ATGR1 · MUJ8.3 · AT3G24170)glutathione-disulfide reductase⌘
A. thalianaNCBI:NP_182308.1 · TAIR:locus:2043408
A. thalianaNCBI:NP_191852.1 · TAIR:locus:2099157 (AT3G62930 · T20O10.30)⌘
A. thalianaNCBI:NP_173594.1 · TAIR:locus:2036906 (F8K7.19 · ATPDI5 · PDI5 · ATPDIL1-1 · F8K7_19 · AT1G21750)ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 5 · PDI-LIKE 1-1 · PROTEIN DISULFIDE ISOMERASE 5⌘
A. thalianaNCBI:NP_193302.1 · TAIR:locus:2130554 (AT4G15670 · FCAALL.355 · DL3875W)⌘
A. thalianaNCBI:NP_174170.1 · TAIR:locus:2032574 (F3M18.8 · F3M18_8 · AT1G28480 · GRX480)⌘
A. thalianaNCBI:NP_182269.1 · TAIR:locus:2062029 (MEE30 · T30B22.23 · ATPDIL2-1 · ATPDI11 · PDI11 · AT2G47470 · UNE5)ARABIDOPSIS THALIANA PROTEIN DISULFIDE ISOMERASE 11 · MATERNAL EFFECT EMBRYO ARREST 30 · UNFERTILIZED EMBRYO SAC 5 · PROTEIN DISULFIDE ISOMERASE 11 · PDI-LIKE 2-1⌘
A. thalianaNCBI:NP_196911.1 · TAIR:locus:2174718 (MUA22.7 · AT5G14070 · ROXY2 · MUA22_7)⌘
A. thalianaNCBI:NP_197361.1 · TAIR:locus:2183013 (T28N17_80 · AT5G18600 · T28N17.80)⌘
A. thalianaNCBI:NP_194602.2 · TAIR:locus:2117793
A. thalianaNCBI:NP_564620.1 · TAIR:locus:2011571
A. thalianaNCBI:NP_200952.1 · TAIR:locus:2163168 (AT5G61440 · MFB13_8 · ACHT5 · MFB13.8)ATYPICAL CYS HIS RICH THIOREDOXIN 5⌘
C. elegansWB:WBGene00014028 (ZK637.10 · trxr-2) · UniProtKB:P30635⌘
C. elegansWB:WBGene00010160 (png-1 · F56G4.5) · UniProtKB:Q9TW67 (F56G4.5 · NGLY1_CAEEL)Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase⌘⌘
C. elegansWB:WBGene00003962 (C14B1.1 · pdi-1) · UniProtKB:Q17967⌘
C. elegansWB:WBGene00003963 (C07A12.4 · pdi-2) · UniProtKB:Q17770⌘
C. elegansWB:WBGene00015752 (C14B9.2) · UniProtKB:P34329⌘
C. elegansWB:WBGene00015168 (B0403.4 · tag-320) · UniProtKB:Q11067⌘
C. elegansWB:WBGene00015062 (trx-1 · B0228.5) · UniProtKB:Q09433⌘
C. elegansWB:WBGene00007099 (B0024.9 · trx-2) · UniProtKB:Q17424⌘
C. elegansWB:WBGene00015553 (C06G3.7 · trxr-1) · UniProtKB:Q17745 (C06G3.7 · TRXR1_CAEEL · trxr-1)Thioredoxin reductase 1⌘⌘
C. elegansWB:WBGene00015510 (C06A6.5) · UniProtKB:Q17688⌘
C. elegansWB:WBGene00017340 (F10D7.3) · UniProtKB:Q19297⌘
C. elegansWB:WBGene00016278 (C30H7.2) · UniProtKB:O01492⌘
C. elegansWB:WBGene00003964 (H06O01.1 · pdi-3) · UniProtKB:O17908⌘
C. elegansWB:WBGene00010794 (LLC1.3) · UniProtKB:O17953⌘
C. elegansWB:WBGene00018358 (F42G8.7) · UniProtKB:O44508⌘
C. elegansWB:WBGene00044608 (C07G1.8 · glrx-22) · UniProtKB:Q3Y400⌘
C. elegansWB:WBGene00008117 (C46F11.2) · UniProtKB:Q93379⌘
C. elegansWB:WBGene00017062 (D2063.3) · UniProtKB:Q95X14⌘
C. elegansWB:WBGene00021826 (Y54E10A.3) · UniProtKB:Q9N2K6⌘
C. elegansWB:WBGene00021933 (Y55F3AR.2) · UniProtKB:Q9N357⌘
C. elegansWB:WBGene00021331 (Y34D9A.6 · glrx-10) · UniProtKB:Q9N456⌘
C. elegansWB:WBGene00022836 (ZK973.11) · UniProtKB:Q9N4L6⌘
C. elegansWB:WBGene00022663 (ZK121.1 · glrx-21) · UniProtKB:Q9N4P2⌘
C. elegansWB:WBGene00021548 (Y44E3A.3) · UniProtKB:Q9TXY8⌘
C. elegansWB:WBGene00013030 (Y49E10.4) · UniProtKB:Q9XTU8⌘
C. elegansWB:WBGene00013029 (glrx-5 · Y49E10.2) · UniProtKB:Q9XTU9⌘
C. elegansWB:WBGene00001045 (dnj-27 · Y47H9C.5) · UniProtKB:Q9XWE1⌘
D. rerioENSEMBL:ENSDARP00000091356
D. rerioENSEMBL:ENSDARP00000059688
D. rerioENSEMBL:ENSDARP00000068966
D. rerioUniProtKB:Q5XJ54 · ZFIN:ZDB-GENE-041010-22 (glrx3)glutaredoxin 3⌘
D. rerioENSEMBL:ENSDARG00000036433 · UniProtKB:Q4V8Q9
D. rerioUniProtKB:Q503X6 · ZFIN:ZDB-GENE-050522-396 (tmx3)thioredoxin-related transmembrane protein 3⌘
D. rerioZFIN:ZDB-GENE-050522-116 (zgc:110010) · UniProtKB:Q503Y5⌘
D. rerioZFIN:ZDB-GENE-040801-20 (zgc:100906) · UniProtKB:Q6DEI4⌘
D. rerioZFIN:ZDB-GENE-060421-2552 (zgc:136472) · UniProtKB:Q6DG87⌘
D. rerioZFIN:ZDB-GENE-040718-162 (zgc:92903) · UniProtKB:Q6DGI6⌘
D. rerioUniProtKB:Q6DH06 · ZFIN:ZDB-GENE-040718-101 (glrx2)glutaredoxin 2⌘
D. rerioZFIN:ZDB-GENE-040426-2238 (zgc:77086) · UniProtKB:Q6NXB9⌘
D. rerioUniProtKB:Q6NY22 · ZFIN:ZDB-GENE-040426-1902 (erp44)endoplasmic reticulum protein 44⌘
D. rerioZFIN:ZDB-GENE-040426-1795 (zgc:77127) · UniProtKB:Q6P131⌘
D. rerioUniProtKB:Q6PBM1 · ZFIN:ZDB-GENE-040426-1957 (glrx5)glutaredoxin 5 homolog (S. cerevisiae)⌘
D. rerioUniProtKB:Q6PFL9 · ZFIN:ZDB-GENE-040426-1951 (txndc5)thioredoxin domain containing 5⌘
D. rerioZFIN:ZDB-GENE-030131-8581 (zgc:56493) · UniProtKB:Q7ZUI4⌘
D. rerioUniProtKB:Q7ZVH2 · ZFIN:ZDB-GENE-030131-5493 (pdia4)protein disulfide isomerase associated 4⌘
D. rerioZFIN:ZDB-GENE-040426-705 (zgc:55398) · UniProtKB:Q7ZW15⌘
D. rerioUniProtKB:Q7ZW23 · ZFIN:ZDB-GENE-040426-701 (txnl1)thioredoxin-like 1⌘
D. rerioUniProtKB:Q803D7 · ZFIN:ZDB-GENE-031002-9 (pdia3)protein disulfide isomerase family A, member 3⌘
D. rerioUniProtKB:Q90WA5 · ZFIN:ZDB-GENE-030131-879 (pdip5)protein disulfide isomerase-related protein (provisional)⌘
D. rerioUniProtKB:Q5XJ42 · ZFIN:ZDB-GENE-041010-11 (glrx)glutaredoxin (thioltransferase)⌘
D. rerioUniProtKB:Q800Q8 · ZFIN:ZDB-GENE-030327-3 (txnrd3)thioredoxin reductase 3⌘
D. rerioUniProtKB:Q803L1 · ZFIN:ZDB-GENE-040120-4 (dldh)dihydrolipoamide dehydrogenase⌘
D. discoideumNCBI:EAL64933.1 · dictyBase:DDB_G0284939 (DDB_G0284939)thioredoxin domain-containing protein⌘
D. discoideumUniProtKB:Q54EW8 · dictyBase:DDB_G0291648 (odhC · lpd · pdhD · bkdD)dihydrolipoamide:NAD oxidoreductase, glycine cleavage system L-protein, dihydrolipoamide dehydrogenase, dihydrolipoyl dehydrogenase⌘
D. discoideumUniProtKB:Q555C8 · dictyBase:DDB_G0274657 (DDB_G0274657)glutaredoxin-related family protein⌘
D. discoideumdictyBase:DDB_G0290015 (Grx1 · grxA · glutaredoxin) · UniProtKB:Q54GP8⌘
D. discoideumUniProtKB:Q8T137 · dictyBase:DDB_G0272754 (GR · gsr)glutathione reductase, glutathione-disulfide reductase⌘
D. discoideumUniProtKB:Q86IA3 · dictyBase:DDB_G0276141 (dis · pdi1 · PDI · Dd-PDI)protein disulfide isomerase⌘
D. discoideumUniProtKB:Q54EN4 · dictyBase:DDB_G0291434 (PDI · pdi2)protein disulfide isomerase⌘
D. discoideumdictyBase:DDB_G0294489 (trxC · thioredoxin · TRX3) · UniProtKB:P29447⌘
D. discoideumdictyBase:DDB_G0287849 (trxD · thioredoxin) · UniProtKB:Q1ZXE0⌘
D. discoideumdictyBase:DDB_G0287227 (trxE · thioredoxin) · UniProtKB:Q54KN7⌘
D. discoideumdictyBase:DDB_G0293378 (DDB_G0293378) · UniProtKB:Q54BW3⌘
D. discoideumdictyBase:DDB_G0271084 (DDB_G0271084) · UniProtKB:Q55BQ6⌘
D. discoideumdictyBase:DDB_G0267952 (DDB_G0267952) · UniProtKB:Q55FU1⌘
D. discoideumUniProtKB:Q75JM6 · dictyBase:DDB_G0276057 (DDB_G0276057)ZZ-type zinc finger-containing protein, thioredoxin domain-containing protein, UBX domain-containing protein, UBA domain-containing protein⌘
D. discoideumUniProtKB:Q869Q9 · dictyBase:DDB_G0274887 (DDB_G0274887)Similar to Acanthamoeba castellanii (Amoeba). disulfide-like protein.⌘
D. discoideumdictyBase:DDB_G0275025 (DDB_G0275025) · UniProtKB:Q869Z0⌘
D. melanogasterUniProtKB:P54399 · FB:FBgn0014002 (dpdi · EP(3)1022 · Dpdi · CG6988 · Pdi · pdi · PDI)Protein disulfide isomerase · disulfide isomerase · protein disulfide isomerase · protein-disulfide isomerase⌘
D. melanogasterFB:FBgn0011761 (thioredoxin-like · CG4193 · deadhead · dhd · thioredoxin · DmTrx-1 · Trx-1) · UniProtKB:P47938⌘
D. melanogasterFB:FBgn0040070 (Trx-2 · DmTrx-2 · thioredoxin-2 · dmtrx-2 · CG31884 · thioredoxin · anon-WO0118547.188 · CG3864) · UniProtKB:Q9V429⌘
D. melanogasterUniProtKB:Q8IFW4 · FB:FBgn0029752 (CG3315 · thioredoxin · TrxT)Thioredoxin T⌘
D. melanogasterUniProtKB:P91938 · FB:FBgn0020653 (CG2151 · Trxr-1 · trxr-1 · gr · l(1)G0481 · Gr · l(1)G0154 · l(1)G0379 · GR · anon-WO03040301.185 · TrxR · DTR · anon-WO03040301.187 · TrxR-1 · dmtrxr-1 · DmTrxR-1 · l(1)G0477 · Trxr1)Glutathione reductase · thioredoxin reductase · Thioredoxin reductase-1 · disulfide reductase · glutathione reductase · thioredoxin reductase-1⌘
D. melanogasterUniProtKB:Q9VNT5 · FB:FBgn0037170 (thioredoxin-reductase-2 · DmTrxR-2 · CG11401 · trxr-2 · Trxr-2 · Trxr2)thioredoxin reductase 2 · thioredoxin reductase⌘
D. melanogasterFB:FBgn0024986 (CG3719 · BcDNA:LD03613 · thioredoxin · EG:132E8.3) · UniProtKB:O76877⌘
D. melanogasterFB:FBgn0033663 (Erp60 · CG8983 · anon-fast-evolving-3D9 · D-ERp60 · ERp60 · anon-EST:fe3D9 · Ov6) · UniProtKB:Q3YMU0⌘
D. melanogasterFB:FBgn0034472 (mtr · CG8517 · thioredoxin) · UniProtKB:Q7K037⌘
D. melanogasterFB:FBgn0030584 (CG14407 · BcDNA:RH03087) · UniProtKB:Q8SXQ5⌘
D. melanogasterFB:FBgn0030734 (CG9912 · CG9911 · LD41494p) · UniProtKB:Q95TL8⌘
D. melanogasterFB:FBgn0036579 (LD24073p · CG5027) · UniProtKB:Q961B9⌘
D. melanogasterFB:FBgn0025678 (DmCaBP1 · BG:DS09218.4 · CaBP1 · AAL28897 · CG5809) · UniProtKB:Q9V438⌘
D. melanogasterFB:FBgn0037498 (CG10029) · UniProtKB:Q9VI96⌘
D. melanogasterFB:FBgn0032514 (anon-WO0118547.80 · CG9302) · UniProtKB:Q9VJZ1⌘
D. melanogasterFB:FBgn0032509 (CG6523) · UniProtKB:Q9VJZ6⌘
D. melanogasterFB:FBgn0035631 (Thioredoxin · Txl · txl · CG5495 · Thioredoxin-like · anon-WO0118547.248) · UniProtKB:Q9VRP3⌘
D. melanogasterFB:FBgn0036442 (CG13473) · UniProtKB:Q9VUG9⌘
D. melanogasterFB:FBgn0036762 (CG7430) · UniProtKB:Q9VVL7⌘
D. melanogasterFB:FBgn0036820 (CG6852 · BcDNA:GH24739) · UniProtKB:Q9VVT6⌘
D. melanogasterFB:FBgn0030329 (anon-EST:Posey253 · p47 · CG1837) · UniProtKB:Q9VYV3⌘
D. melanogasterFB:FBgn0035334 (CG8993 · thioredoxin) · UniProtKB:Q9W022⌘
D. melanogasterFB:FBgn0034658 (CG7975 · Grx-1) · UniProtKB:Q9W2D1⌘
E. coliUniProtKB:P0A9P0 · ECOLI:E3-MONOMER (b0116 · B0116 · lpd · LpdA · Lpd · ECK0115 · Dhl · dhl · lpdA · E3)E3 component is part of three enzyme complexes · E3 monomer · lipoamide dehydrogenase⌘
E. coliUniProtKB:P0AC62 · ECOLI:OX-GLUTAREDOXIN-C
E. coliUniProtKB:P0AC69 · ECOLI:EG12181-MONOMER (ydhD · b1654 · ECK1650 · GrxD · grxD)glutaredoxin 4⌘
E. coliUniProtKB:P06715 · ECOLI:GLUTATHIONE-REDUCT-NADPH-MONOMER (gor · gorA · b3500 · Gor · ECK3485)glutathione reductase (NADPH)⌘
E. coliUniProtKB:P27306 · ECOLI:UDHA-MONOMER (udhA · sth · Sth · sthA · b3962 · ECK3954 · SthA)⌘
E. coliUniProtKB:P0AGG4 · ECOLI:OX-THIOREDOXIN2-MONOMER (trxC · yfiG · ECK2580 · b2582)oxidized thioredoxin 2⌘
E. coliUniProtKB:P0AA25 · ECOLI:OX-THIOREDOXIN-MONOMER
E. coliUniProtKB:P77212 · ECOLI:G6174-MONOMER (b0304 · ECK0303 · ykgC · YkgC)predicted oxidoreductase with FAD/NAD(P)-binding domain and dimerization domain⌘
G. gallusNCBI:XP_421826 · ENTREZ:423968
G. gallusNCBI:XP_419079 · ENTREZ:420994
G. gallusNCBI:XP_420095 · ENTREZ:374091
G. gallusNCBI:XP_001235017 · ENTREZ:771783
G. gallusNCBI:NP_001116249 · ENTREZ:416031
G. gallusNCBI:XP_416183 · ENTREZ:417942
G. gallusNCBI:XP_422097 · ENTREZ:424249
G. gallusNCBI:XP_422200 · ENTREZ:424357
G. gallusNCBI:NP_001116163 · ENTREZ:416782
G. gallusNCBI:XP_428969 · ENTREZ:431417
G. gallusNCBI:XP_424463 · ENTREZ:426854
G. gallusNCBI:XP_419113 · ENTREZ:421027
G. gallusNCBI:XP_419952 · ENTREZ:421940
G. gallusNCBI:XP_421968 · ENTREZ:424115
G. gallusUniProtKB:P79764 (GLRX1_CHICK · Glutaredoxin-1 · P79764 · GLRX · IPI00584182 · GRX) · ENTREZ:396069⌘
G. gallusENTREZ:396376 · UniProtKB:P12244 (GSBP_CHICK · P12244 · IPI00597613)Dolichyl-diphosphooligosaccharide--protein glycotransferase⌘
G. gallusENTREZ:373899 · UniProtKB:Q8JG64 (GRP58 · ERP57 · PDIA3_CHICK · IPI00575271 · PDIA3 · Q8JG64)Protein disulfide-isomerase A3⌘
G. gallusUniProtKB:P08629 (Thioredoxin · P08629 · TXN · THIO_CHICK · IPI00601777) · ENTREZ:396437⌘
G. gallusUniProtKB:Q5F3B7 (Q5F3B7 · RCJMB04_23a5 · IPI00595527) · ENTREZ:418082⌘
G. gallusUniProtKB:Q5ZIM7 (IPI00574971 · RCJMB04_24o2 · Q5ZIM7) · ENTREZ:420867⌘
G. gallusUniProtKB:Q5ZJY6 (Q5ZJY6 · IPI00589732 · RCJMB04_14g3) · ENTREZ:426978⌘
G. gallusUniProtKB:Q5ZK20 (Q5ZK20 · RCJMB04_13l7 · IPI00589958) · ENTREZ:420785⌘
G. gallusUniProtKB:Q5ZK23 (RCJMB04_13k21 · IPI00583765 · Q5ZK23) · ENTREZ:423440⌘
G. gallusENTREZ:417699 · UniProtKB:Q5ZM32 (Q5ZM32 · RCJMB04_3f8 · IPI00601538)Dihydrolipoyl dehydrogenase⌘
H. sapiensENSEMBL:ENSG00000077232 · UniProtKB:Q8IXB1 (UNQ495/PRO1012 · ERDJ5 · DNAJC10 · IPI00844115 · IPI00293260 · DJC10_HUMAN · Q8IXB1)DnaJ homolog subfamily C member 10⌘
H. sapiensENSEMBL:ENSG00000091140 · UniProtKB:P09622 (GCSL · P09622 · LAD · PHE3 · DLD · IPI00015911 · DLDH_HUMAN)Dihydrolipoyl dehydrogenase, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000139055 · UniProtKB:Q96DN0 (IPI00061005 · ERP27 · C12orf46 · Q96DN0 · ERP27_HUMAN · UNQ781/PRO1575)Endoplasmic reticulum resident protein ERp27⌘
H. sapiensENSEMBL:ENSG00000173221 · UniProtKB:P35754 (Glutaredoxin-1 · GLRX1_HUMAN · GLRX · IPI00219025 · GRX · P35754)⌘
H. sapiensENSEMBL:ENSG00000023572 · UniProtKB:Q9NS18 (GLRX2_HUMAN · IPI00007045 · CGI-133 · Q9NS18 · IPI00100044 · GRX2 · GLRX2)Glutaredoxin-2, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000108010 · UniProtKB:O76003 (Glutaredoxin-3 · IPI00008552 · HUSSY-22 · GLRX3 · GLRX3_HUMAN · O76003 · PICOT · TXNL2)⌘
H. sapiensENSEMBL:ENSG00000182512 · UniProtKB:Q86SX6 (GLRX5_HUMAN · Q86SX6 · IPI00333763 · C14orf87 · GLRX5)Glutaredoxin-related protein 5⌘
H. sapiensENSEMBL:ENSG00000118990 · UniProtKB:A6NLA2 (IPI00160508 · A6NLA2 · GLRXL_HUMAN · GLRXL)Putative glutaredoxin-like protein⌘
H. sapiensENSEMBL:ENSG00000104687 · UniProtKB:P00390 (GLUR · IPI00759575 · IPI00016862 · GSHR_HUMAN · P00390 · GRD1 · GSR)Glutathione reductase, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000185624 · UniProtKB:P07237 (PDIA1 · PDIA1_HUMAN · P4HB · PDI · P07237 · ERBA2L · PO4DB · IPI00010796)Protein disulfide-isomerase⌘
H. sapiensENSEMBL:ENSG00000185615 · UniProtKB:Q13087 (PDIA2_HUMAN · PDIP · PDIA2 · Q13087 · IPI00011571)Protein disulfide-isomerase A2⌘
H. sapiensENSEMBL:ENSG00000167004 · UniProtKB:P30101 (PDIA3_HUMAN · IPI00025252 · GRP58 · ERP60 · P30101 · ERP57 · PDIA3)Protein disulfide-isomerase A3⌘
H. sapiensENSEMBL:ENSG00000155660 · UniProtKB:P13667 (PDIA4 · PDIA4_HUMAN · ERP72 · P13667 · ERP70 · IPI00009904)Protein disulfide-isomerase A4⌘
H. sapiensENSEMBL:ENSG00000065485 · UniProtKB:Q14554 (Q14554 · PDIA5_HUMAN · IPI00031479 · PDIR · PDIA5)Protein disulfide-isomerase A5⌘
H. sapiensENSEMBL:ENSG00000143870 · UniProtKB:Q15084 (TXNDC7 · PDIA6 · Q15084 · PDIA6_HUMAN · IPI00299571 · IPI00644989)Protein disulfide-isomerase A6⌘
H. sapiensENSEMBL:ENSG00000169340 · UniProtKB:Q8N807 (Q8N807 · PDILT_HUMAN · IPI00646007 · PDILT)Protein disulfide-isomerase-like protein of the testis⌘
H. sapiensENSEMBL:ENSG00000100348 · UniProtKB:Q99757 (THIOM_HUMAN · IPI00878215 · TRX2 · TXN2 · Q99757)Thioredoxin, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000136810 · UniProtKB:P10599 (TRX1 · Thioredoxin · P10599 · IPI00216298 · TXN · TRDX · TRX · THIO_HUMAN)⌘
H. sapiensENSEMBL:ENSG00000198431 · UniProtKB:Q16881 (IPI00884896 · KDRF · IPI00871867 · IPI00554786 · IPI00885213 · TRXR1_HUMAN · IPI00783641 · IPI00847482 · Q16881 · TXNRD1)Thioredoxin reductase 1, cytoplasmic⌘
H. sapiensENSEMBL:ENSG00000184470 · UniProtKB:Q9NNW7 (IPI00220566 · TRXR2 · KIAA1652 · TXNRD2 · Q9NNW7 · IPI00377218 · IPI00157820 · IPI00477542 · TRXR2_HUMAN)Thioredoxin reductase 2, mitochondrial⌘
H. sapiensENSEMBL:ENSG00000197763 · UniProtKB:Q86VQ6 (IPI00013954 · TGR · TRXR3 · TXNRD3 · Q86VQ6 · TRXR3_HUMAN)Thioredoxin reductase 3⌘
H. sapiensENSEMBL:ENSG00000166479 · UniProtKB:Q96JJ7 (TMX3 · IPI00555585 · IPI00064193 · Q96JJ7 · TXD10_HUMAN · KIAA1830 · TXNDC10)Protein disulfide-isomerase TXNDC10⌘
H. sapiensENSEMBL:ENSG00000168454 · UniProtKB:Q86VQ3 (IPI00410323 · SPTRX1 · TXND2_HUMAN · IPI00479021 · TXNDC2 · Q86VQ3 · SPTRX)Thioredoxin domain-containing protein 2⌘
H. sapiensENSEMBL:ENSG00000023318 · UniProtKB:Q9BS26 (Q9BS26 · TXND4_HUMAN · UNQ532/PRO1075 · IPI00401264 · KIAA0573 · ERP44 · TXNDC4)Thioredoxin domain-containing protein 4⌘
H. sapiensENSEMBL:ENSG00000188428 · UniProtKB:Q8NBS9 (TLP46 · Q8NBS9 · IPI00171438 · TXNDC5 · TXND5_HUMAN · UNQ364/PRO700)Thioredoxin domain-containing protein 5⌘
H. sapiensENSEMBL:ENSG00000204193 · UniProtKB:Q6A555 (TXNDC8 · IPI00607678 · Q6A555 · TXND8_HUMAN · TRX6 · SPTRX3 · IPI00160585)Thioredoxin domain-containing protein 8⌘
H. sapiensENSEMBL:ENSG00000091164 · UniProtKB:O43396 (O43396 · IPI00305692 · TRP32 · TXL · TXNL1 · TXNL1_HUMAN · TXNL)Thioredoxin-like protein 1⌘
M. musculusNCBI:NP_001074539 · MGI:MGI:1916441 (Pdia2 · Pdip · Pdipl)protein disulfide isomerase associated 2⌘
M. musculusUniProtKB:Q9DC23 · MGI:MGI:1914111 (JPDI · D2Ertd706e · Dnajc10)DnaJ (Hsp40) homolog, subfamily C, member 10⌘
M. musculusUniProtKB:O08749 · MGI:MGI:107450 (Dld)branched chain alpha-keto acid dehydrogenase complex subunit E3 · dihydrolipoamide dehydrogenase · dihydrolipoyl dehydrogenase⌘
M. musculusUniProtKB:Q9D8U3 · MGI:MGI:1916437 (Erp27)endoplasmic reticulum protein 27⌘
M. musculusMGI:MGI:2135625 (Grx1 · TTase · Glrx · D13Wsu156e · glutaredoxin) · UniProtKB:Q9QUH0⌘
M. musculusUniProtKB:Q923X4 · MGI:MGI:1916617 (Grx2 · Glrx2)glutaredoxin 2 (thioltransferase)⌘
M. musculusUniProtKB:Q9CQM9 · MGI:MGI:1353653 (Glrx3 · Txnl2 · PICOT)PKC interacting cousin of thioredoxin · glutaredoxin 3⌘
M. musculusUniProtKB:Q80Y14 · MGI:MGI:1920296 (Glrx5)glutaredoxin 5 homolog (S. cerevisiae)⌘
M. musculusUniProtKB:P47791 · MGI:MGI:95804 (Gr-1 · Gsr · Gr1 · D8Ertd238e)glutathione reductase⌘
M. musculusUniProtKB:P09103 · MGI:MGI:97464 (Thbp · ERp59 · P4hb)prolyl 4-hydroxylase, beta polypeptide · protein disulfide isomerase⌘
M. musculusUniProtKB:P27773 · MGI:MGI:95834 (Grp58 · ERp57 · Erp · Pdia3 · PDI · Plca · ERp60 · ERp61 · PDI-Q2)protein disulfide isomerase associated 3⌘
M. musculusUniProtKB:P08003 · MGI:MGI:104864 (ERp72 · Pdia4 · Cai)protein disulfide isomerase associated 4⌘
M. musculusUniProtKB:Q921X9 · MGI:MGI:1919849 (Pdir · Pdia5)protein disulfide isomerase associated 5⌘
M. musculusUniProtKB:Q922R8 · MGI:MGI:1919103 (Txndc7 · P5 · CaBP5 · Pdia6)protein disulfide isomerase associated 6⌘
M. musculusUniProtKB:Q9DAN1 · MGI:MGI:1919080 (Pdilt · PDILT)protein disulfide isomerase-like, testis expressed⌘
M. musculusUniProtKB:P97493 · MGI:MGI:1929468 (Txn2)thioredoxin 2⌘
M. musculusUniProtKB:P10639 · MGI:MGI:98874 (Trx1 · Txn1)thioredoxin 1⌘
M. musculusUniProtKB:Q9JMH6 · MGI:MGI:1354175 (Txnrd1 · TR · TrxR1 · TR1)TR alpha · thioredoxin reductase 1⌘
M. musculusUniProtKB:Q9JLT4 · MGI:MGI:1347023 (TGR · TR3 · Txnrd2 · ESTM573010)TR beta · thioredoxin reductase 2⌘
M. musculusUniProtKB:Q99MD6 · MGI:MGI:2386711 (Txnrd3 · Tgr · TR2)thioredoxin reductase 3⌘
M. musculusUniProtKB:Q8BXZ1 · MGI:MGI:2442418 (Txndc10 · Tmx3)thioredoxin-related transmembrane protein 3⌘
M. musculusUniProtKB:Q6P902 · MGI:MGI:2389312 (Txndc2 · Sptrx-1)thioredoxin domain containing 2 (spermatozoa)⌘
M. musculusUniProtKB:Q9D1Q6 · MGI:MGI:1923549 (Txndc4 · Erp44)endoplasmic reticulum protein 44⌘
M. musculusUniProtKB:Q91W90 · MGI:MGI:2145316 (PC-TRP · Txndc5)thioredoxin domain containing 5⌘
M. musculusUniProtKB:Q69AB2 · MGI:MGI:1914652 (Sptrx-3 · Sptrx3 · Txndc8)thioredoxin domain containing 8⌘
M. musculusUniProtKB:Q8CDN6 · MGI:MGI:1860078 (Txnl1 · 32kDa · TRP32)thioredoxin-like 1⌘
R. norvegicusNCBI:XP_001069239 · RGD:1308383 (Glrx5)glutaredoxin 5⌘
R. norvegicusNCBI:XP_213263 · RGD:1305164 (Pdia2)protein disulfide isomerase family A, member 2⌘
R. norvegicusNCBI:XP_001072640 · RGD:1565381
R. norvegicusNCBI:XP_001081896 · RGD:1562443 (RGD1562443)similar to glutaredoxin 1 (thioltransferase)⌘
R. norvegicusNCBI:XP_001063895 · RGD:1592777 (LOC682967)similar to Protein disulfide-isomerase TXNDC10 precursor (Thioredoxin domain-containing protein 10)⌘
R. norvegicusNCBI:XP_216204 · RGD:1308363 (Txnrd3)thioredoxin reductase 3⌘
R. norvegicusNCBI:XP_001074203 · RGD:1597626 (LOC686458)similar to Glutaredoxin-1 (Thioltransferase-1) (TTase-1)⌘
R. norvegicusNCBI:XP_225257 · RGD:1305328
R. norvegicusNCBI:XP_001071626 · RGD:1562624 (RGD1562624)similar to RIKEN cDNA 1700001F09⌘
R. norvegicusNCBI:XP_001073180 · RGD:1584297
R. norvegicusNCBI:XP_001057599 · RGD:1590630 (LOC680530)similar to Glutaredoxin-1 (Thioltransferase-1) (TTase-1)⌘
R. norvegicusNCBI:XP_001081076 · RGD:1593581
R. norvegicusUniProtKB:Q498R3 · RGD:1307813 (Dnajc10)DnaJ (Hsp40) homolog, subfamily C, member 10⌘
R. norvegicusUniProtKB:Q6P6R2 · RGD:735073 (Dld)dihydrolipoamide dehydrogenase⌘
R. norvegicusUniProtKB:Q9ESH6 · RGD:70951 (Glrx1)glutaredoxin 1 (thioltransferase)⌘
R. norvegicusRGD:1307950 (Glrx2) · UniProtKB:Q6AXW1 (IPI00650125 · Grx2 · Glrx2 · GLRX2_RAT · IPI00371327 · Q6AXW1)glutaredoxin 2 · Glutaredoxin-2, mitochondrial⌘⌘
R. norvegicusUniProtKB:Q9JLZ1 (IPI00204225 · Glutaredoxin-3 · Picot · IPI00553899 · Glrx3 · GLRX3_RAT · Q9JLZ1 · Txnl2) · RGD:69414 (Glrx3)glutaredoxin 3⌘⌘
R. norvegicusUniProtKB:P70619 · RGD:621747 (Gsr)glutathione reductase⌘
R. norvegicusUniProtKB:P04785 · RGD:3244 (P4hb)prolyl 4-hydroxylase, beta polypeptide⌘
R. norvegicusUniProtKB:P11598 · RGD:68430 (Pdia3)protein disulfide isomerase family A, member 3⌘
R. norvegicusUniProtKB:P38659 · RGD:619835 (Pdia4)protein disulfide isomerase family A, member 4⌘
R. norvegicusUniProtKB:Q5I0H9 · RGD:1359236 (Pdia5)protein disulfide isomerase family A, member 5⌘
R. norvegicusUniProtKB:Q63081 · RGD:628688 (Pdia6)protein disulfide isomerase family A, member 6⌘
R. norvegicusUniProtKB:Q5XI02 · RGD:1307822 (Pdilt)protein disulfide isomerase-like protein of the testis⌘
R. norvegicusUniProtKB:P97615 · RGD:71040 (Txn2)thioredoxin 2⌘
R. norvegicusUniProtKB:P11232 · RGD:621157 (Txn1)thioredoxin 1⌘
R. norvegicusUniProtKB:O89049 · RGD:61959 (Txnrd1)thioredoxin reductase 1⌘
R. norvegicusRGD:61960 (Txnrd2) · UniProtKB:Q9Z0J5 (Q9Z0J5 · TRXR2_RAT · Txnrd2 · IPI00476563 · IPI00196118 · Trxr2)thioredoxin reductase 2 · Thioredoxin reductase 2, mitochondrial⌘⌘
R. norvegicusRGD:1359251 (Txndc2) · UniProtKB:Q5XHX6 (Sptrx1 · Txndc2 · Q5XHX6 · IPI00608181 · Sptrx · IPI00363611 · TXND2_RAT)thioredoxin domain containing 2 (spermatozoa) · Thioredoxin domain-containing protein 2⌘⌘
R. norvegicusUniProtKB:Q69AB1 · RGD:1303121 (Txndc8)thioredoxin domain containing 8⌘
R. norvegicusUniProtKB:Q920J4 · RGD:621717 (Txnl1)thioredoxin-like 1⌘
R. norvegicusUniProtKB:Q5VLR5 · RGD:1309176 (Txndc4)thioredoxin domain containing 4 (endoplasmic reticulum)⌘
R. norvegicusRGD:1359159 · UniProtKB:Q6AXY5
R. norvegicusUniProtKB:Q6AY00 · RGD:1359170 (LOC305806)similar to glutaredoxin 1 (thioltransferase); glutaredoxin⌘
S. cerevisiaeUniProtKB:P09624 · SGD:S000001876 (LPD1 · HPD1 · YFL018C)Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes⌘
S. cerevisiaeUniProtKB:P32474 · SGD:S000002926 (YDR518W · EUG1)Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p⌘
S. cerevisiaeUniProtKB:P25373 · SGD:S000000540 (YCL035C · GRX1)Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair⌘
S. cerevisiaeUniProtKB:P17695 · SGD:S000002921 (GRX2 · YDR513W · TTR1)Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress⌘
S. cerevisiaeUniProtKB:Q03835 · SGD:S000002505 (GRX3 · YDR098C)Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase⌘
S. cerevisiaeUniProtKB:P32642 · SGD:S000000976 (GRX4 · YER174C)Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase⌘
S. cerevisiaeUniProtKB:Q02784 · SGD:S000005980 (GRX5 · YPL059W)Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase⌘
S. cerevisiaeUniProtKB:Q12438 · SGD:S000002168 (YDL010W · GRX6)Cis-golgi localized monothiol glutaredoxin that binds an iron-sulfur cluster⌘
S. cerevisiaeUniProtKB:P38068 · SGD:S000000218 (GRX7 · YBR014C)Cis-golgi localized monothiol glutaredoxin⌘
S. cerevisiaeUniProtKB:P41921 · SGD:S000006012 (LPG17 · GLR1 · YPL091W)Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione⌘
S. cerevisiaeUniProtKB:Q02733 · SGD:S000005938 (IRC15 · YPL017C)Microtubule associated protein⌘
S. cerevisiaeUniProtKB:P17967 · SGD:S000000548 (MFP1 · YCL043C · PDI1 · TRG1)Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds⌘
S. cerevisiaeUniProtKB:P22217 · SGD:S000004033 (TRX1 · YLR043C · LMA1)Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance⌘
S. cerevisiaeUniProtKB:P22803 · SGD:S000003441 (TRX2 · YGR209C · LMA1)Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance⌘
S. cerevisiaeUniProtKB:P25372 · SGD:S000000679 (YCR083W · TRX3)Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p⌘
S. pombeUniProtKB:O00087 · GeneDB_Spombe:SPAC1002.09c (dldh · dld1 · SPAC1002.09c)dihydrolipoamide dehydrogenase Dld1⌘
S. pombeUniProtKB:O36032 · GeneDB_Spombe:SPAC4F10.20 (SPAC4F10.20 · grx1)glutaredoxin Grx1⌘
S. pombeUniProtKB:Q9UTI2 · GeneDB_Spombe:SPAC15E1.09 (SPAC15E1.09 · grx2)glutaredoxin Grx2⌘
S. pombeUniProtKB:Q9Y7N3 · GeneDB_Spombe:SPCC1450.06c (grx3 · SPCC1450.06c)monothiol glutaredoxin Grx3⌘
S. pombeUniProtKB:Q9HDW8 · GeneDB_Spombe:SPAPB2B4.02 (SPAPB2B4.02 · grx5)monothiol glutaredoxin Grx5⌘
S. pombeUniProtKB:O74790 · GeneDB_Spombe:SPBC26H8.06 (grx4 · SPBC26H8.06)glutaredoxin Grx4⌘
S. pombeUniProtKB:P78965 · GeneDB_Spombe:SPBC17A3.07 (SPBC17A3.07 · pgr1)glutathione reductase⌘
S. pombeUniProtKB:Q10057 · GeneDB_Spombe:SPAC1F5.02 (SPAC1F5.02)protein disulfide isomerase⌘
S. pombeUniProtKB:O13811 · GeneDB_Spombe:SPAC17H9.14c (SPAC17H9.14c)protein disulfide isomerase⌘
S. pombeUniProtKB:O14463 · GeneDB_Spombe:SPAC7D4.07c (SPAC7D4.07c · trx1)cytosolic thioredoxin Trx1⌘
S. pombeUniProtKB:O94504 · GeneDB_Spombe:SPBC12D12.07c (SPBC12D12.07c · trx2)mitochondrial thioredoxin Trx2⌘
S. pombeUniProtKB:Q9USR1 · GeneDB_Spombe:SPBC577.08c (trx3 · txl1 · SPBC577.08c)thioredoxin-like I protein Txl1⌘
ProteinPublicationCurator Notes
UniProtKB:P22803 · SGD:S000003441PMID:10906327 Bréheĺin C, et al. Characterization of determinants for the specificity of Arabidopsis thioredoxins h in yeast complementation. J Biol Chem. 2000 Oct 13;275(41):31641-7.The A. thaliana protein AT5G15410.1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows partial complementation of a yeast trx1 trx2 double mutant by A. thaliana AtTRX3 (AT5G15410.1). AtTRX3 induces methionine sulfoxide assimilation and restores a normal cell cycle.
UniProtKB:P22217 · SGD:S000004033PMID:10906327 Bréheĺin C, et al. Characterization of determinants for the specificity of Arabidopsis thioredoxins h in yeast complementation. J Biol Chem. 2000 Oct 13;275(41):31641-7.The A. thaliana protein AT5G39950.1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows partial complementation of a yeast trx1 trx2 double mutant by A. thaliana AtTRX2 (AT5G39950.1). AtTRX2 induces methionine sulfoxide assimilation and restores a normal cell cycle.
UniProtKB:P22217 · SGD:S000004033PMID:16299179 Lee MY, et al. Induction of thioredoxin is required for nodule development to reduce reactive oxygen species levels in soybean roots. Plant Physiol. 2005 Dec;139(4):1881-9.The G. max protein GmTRX complements a homologous mutation in S. cerevisiae. This paper shows that soybean GmTRX complements a yeast trx1 trx2 double mutant.
UniProtKB:P17967 · SGD:S000000548PMID:8385117 Günther R, et al. Functional replacement of the Saccharomyces cerevisiae Trg1/Pdi1 protein by members of the mammalian protein disulfide isomerase family. J Biol Chem. 1993 Apr 15;268(11):7728-32.The M. musculus protein P08003 complements a homologous mutation in S. cerevisiae. This paper shows that murine ERp72 (P08003) partially complements a yeast pdi1 null mutant.
UniProtKB:P17967 · SGD:S000000548PMID:7499282 Laboissiere MC, et al. The essential function of protein-disulfide isomerase is to unscramble non-native disulfide bonds. J Biol Chem. 1995 Nov 24;270(47):28006-9.The R. norvegicus protein PDI complements a homologous mutation in S. cerevisiae.
UniProtKB:P17967 · SGD:S000000548PMID:15377672 Xiao R, et al. The contributions of protein disulfide isomerase and its homologues to oxidative protein folding in the yeast endoplasmic reticulum. J Biol Chem. 2004 Nov 26;279(48):49780-6.The R. norvegicus protein PDI complements a homologous mutation in S. cerevisiae. This paper shows that rat PDI partially complements a yeast pdi1 null mutant.
UniProtKB:P17967 · SGD:S000000548PMID:16889384 Zhang W, et al. Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins. Biotechnol Prog. 2006 Jul-Aug;22(4):1090-5.The S. cerevisiae protein PDI1 was expressed in P. pastoris, but complementation was not directly tested. This paper shows heterologous overexpression of S. cerevisiae PDI1 in P. pastoris.
UniProtKB:P22803 · SGD:S000003441PMID:17098852 Traverso JA, et al. PsTRXh1 and PsTRXh2 are both pea h-type thioredoxins with antagonistic behavior in redox imbalances. Plant Physiol. 2007 Jan;143(1):300-11.The P. sativum protein PsTRXh1 complements a homologous mutation in S. cerevisiae. P. sativum PsTRXh1 complements a yeast trx1 trx2 double mutant.
UniProtKB:P22217 · SGD:S000004033PMID:17098852 Traverso JA, et al. PsTRXh1 and PsTRXh2 are both pea h-type thioredoxins with antagonistic behavior in redox imbalances. Plant Physiol. 2007 Jan;143(1):300-11.The P. sativum protein PsTRXh2 complements a homologous mutation in S. cerevisiae. P. sativum PsTRXh2 complements a yeast trx1 trx2 double mutant.
UniProtKB:P22803 · SGD:S000003441PMID:16299179 Lee MY, et al. Induction of thioredoxin is required for nodule development to reduce reactive oxygen species levels in soybean roots. Plant Physiol. 2005 Dec;139(4):1881-9.The G. max protein GmTRX complements a homologous mutation in S. cerevisiae. This paper shows that soybean GmTRX complements a yeast trx1 trx2 double mutant.
UniProtKB:P22217 · SGD:S000004033PMID:10906327 Bréheĺin C, et al. Characterization of determinants for the specificity of Arabidopsis thioredoxins h in yeast complementation. J Biol Chem. 2000 Oct 13;275(41):31641-7.The A. thaliana protein AT5G15410.1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows partial complementation of a yeast trx1 trx2 double mutant by A. thaliana AtTRX3 (AT5G15410.1). AtTRX3 induces methionine sulfoxide assimilation and restores a normal cell cycle.
UniProtKB:P22803 · SGD:S000003441PMID:10906327 Bréheĺin C, et al. Characterization of determinants for the specificity of Arabidopsis thioredoxins h in yeast complementation. J Biol Chem. 2000 Oct 13;275(41):31641-7.The A. thaliana protein AT5G39950.1 was expressed in S. cerevisiae, but complementation was not directly tested. This paper shows partial complementation of a yeast trx1 trx2 double mutant by A. thaliana AtTRX2 (AT5G39950.1). AtTRX2 induces methionine sulfoxide assimilation and restores a normal cell cycle.
UniProtKB:P17967 · SGD:S000000548PMID:8385117 Günther R, et al. Functional replacement of the Saccharomyces cerevisiae Trg1/Pdi1 protein by members of the mammalian protein disulfide isomerase family. J Biol Chem. 1993 Apr 15;268(11):7728-32.The R. norvegicus protein ERp61 does not complement a homologous mutation in S. cerevisiae.
UniProtKB:P17967 · SGD:S000000548PMID:8385117 Günther R, et al. Functional replacement of the Saccharomyces cerevisiae Trg1/Pdi1 protein by members of the mammalian protein disulfide isomerase family. J Biol Chem. 1993 Apr 15;268(11):7728-32.The M. musculus protein P09103 complements a homologous mutation in S. cerevisiae. This paper shows that murine ERp59/PDI (P09103) partially complements a yeast pdi1 null mutant.
UniProtKB:P22803 · SGD:S000003441PMID:17098852 Traverso JA, et al. PsTRXh1 and PsTRXh2 are both pea h-type thioredoxins with antagonistic behavior in redox imbalances. Plant Physiol. 2007 Jan;143(1):300-11.The P. sativum protein PsTRXh1 complements a homologous mutation in S. cerevisiae. P. sativum PsTRXh1 complements a yeast trx1 trx2 double mutant.
UniProtKB:P22217 · SGD:S000004033PMID:17098852 Traverso JA, et al. PsTRXh1 and PsTRXh2 are both pea h-type thioredoxins with antagonistic behavior in redox imbalances. Plant Physiol. 2007 Jan;143(1):300-11.The P. sativum protein PsTRXh2 complements a homologous mutation in S. cerevisiae. P. sativum PsTRXh2 complements a yeast trx1 trx2 double mutant.
UniProtKB:P09624 · SGD:S000001876PMID:8894701 Lanterman MM, et al. Functional analysis in Saccharomyces cerevisiae of naturally occurring amino acid substitutions in human dihydrolipoamide dehydrogenase. Hum Mol Genet. 1996 Oct;5(10):1643-8.The H. sapiens protein P09622 complements a homologous mutation in S. cerevisiae.
UniProtKB:P09624 · SGD:S000001876PMID:21930696 Vaubel RA, et al. Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells. J Biol Chem. 2011 Nov 18;286(46):40232-45.The H. sapiens protein DLD complements a homologous mutation in S. cerevisiae.
UniProtKB:P09624 · SGD:S000001876PMID:8894701 Lanterman MM, et al. Functional analysis in Saccharomyces cerevisiae of naturally occurring amino acid substitutions in human dihydrolipoamide dehydrogenase. Hum Mol Genet. 1996 Oct;5(10):1643-8.The H. sapiens protein DLD complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (3)
ENSEMBL:ENSG00000182512 · UniProtKB:Q86SX6#248600 MAPLE SYRUP URINE DISEASE;;MSUD;;BRANCHED-CHAIN KETOACIDURIA;;BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE DEFICIENCY;;BCKD DEFICIENCY;;KETO ACID DECARBOXYLASE DEFICIENCYMAPLE SYRUP URINE DISEASE, CLASSIC, INCLUDED;;MAPLE SYRUP URINE DISEASE, INTERMEDIATE, INCLUDED;;MAPLE SYRUP URINE DISEASE, INTERMITTENT, INCLUDED;;MAPLE SYRUP URINE DISEASE, THIAMINE-RESPONSIVE, INCLUDED;;MAPLE SYRUP URINE DISEASE, E3-DEFICIENT, WITH LACTIC ACIDOSIS, INCLUDED;;MAPLE SYRUP URINE DISEASE, TYPE IA, INCLUDED; MSUD1A, INCLUDED;;MAPLE SYRUP URINE DISEASE, TYPE IB, INCLUDED; MSUD1B, INCLUDED;;MAPLE SYRUP URINE DISEASE, TYPE II, INCLUDED; MSUD2, INCLUDED; MAPLESYRUP URINE DISEASE, TYPE III, INCLUDED; MSUD3, INCLUDED;;LIPOAMIDE DEHYDROGENASE DEFICIENCY, LACTIC ACIDOSIS DUE TO;;LACTIC ACIDOSIS, CONGENITAL INFANTILE, DUE TO LAD DEFICIENCY, INCLUDED;;DIHYDROLIPOAMIDE DEHYDROGENASE DEFICIENCY, INCLUDED;;DLD DEFICIENCY, INCLUDED
ENSEMBL:ENSG00000104687 · UniProtKB:P00390#205950 ANEMIA, SIDEROBLASTIC, PYRIDOXINE-REFRACTORY, AUTOSOMAL RECESSIVE
UniProtKB:P09624 · SGD:S000001876+138300 GLUTATHIONE REDUCTASE; GSRGLUTATHIONE REDUCTASE, HEMOLYTIC ANEMIA DUE TO DEFICIENCY OF, IN REDCELLS, INCLUDED
SGD Disease Papers (3)
UniProtKB:Q02784 · SGD:S000005980PMID:9300813 Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10
PMID:12134146 Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
UniProtKB:Q02784 · SGD:S000005980PMID:16110529 Wingert RA, et al. (2005) Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature 436(7053):1035-39
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu