P-POD: Princeton Protein Orthology Database: GO3/Jaccard279

This family has 65 members: 11 Arabidopsis thaliana, 3 Caenorhabditis elegans, 7 Danio rerio, 5 Dictyostelium discoideum, 4 Drosophila melanogaster, 4 Escherichia coli, 4 Gallus gallus, 5 Homo sapiens, 7 Mus musculus, 6 Rattus norvegicus, 5 Saccharomyces cerevisiae, 4 Schizosaccharomyces pombe.

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GO3/Jaccard279
65 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2152916 (K16H17.13 · K16H17_13 · AT5G24420) · NCBI:NP_197830.1⌘
A. thalianaNCBI:NP_563844.1 · TAIR:locus:2012305 (F14J9_8 · F14J9.8 · G6PD4 · AT1G09420)GLUCOSE-6-PHOSPHATE DEHYDROGENASE 4⌘
A. thalianaNCBI:NP_190505.1 · TAIR:locus:2082916 (F2K15.220 · AT3G49360)⌘
A. thalianaNCBI:NP_198892.1 · TAIR:locus:2154805 (AT5G40760 · K1B16.1 · K1B16_1 · G6PD6)GLUCOSE-6-PHOSPHATE DEHYDROGENASE 6⌘
A. thalianaNCBI:NP_198428.1 · TAIR:locus:2165154 (MWP19.3 · G6PD1 · AT5G35790)GLUCOSE-6-PHOSPHATE DEHYDROGENASE 1⌘
A. thalianaNCBI:NP_189366.1 · TAIR:locus:2086558 (G6PD5 · AT3G27300 · K17E12.12)glucose-6-phosphate dehydrogenase 5⌘
A. thalianaNCBI:NP_196815.2 · TAIR:locus:2179887 (T19L5_70 · T19L5.70 · G6PD2 · AT5G13110)GLUCOSE-6-PHOSPHATE DEHYDROGENASE 2⌘
A. thalianaNCBI:NP_172826.1 · TAIR:locus:2023842 (AT1G13700 · F21F23_14 · F21F23.14)⌘
A. thalianaNCBI:NP_568445.1 · TAIR:locus:2152906 (K16H17_11 · K16H17.11 · emb2024 · AT5G24400)embryo defective 2024⌘
A. thalianaNCBI:NP_173838.1 · TAIR:locus:2032412 (G6PD3 · F3I6.22 · F3I6_22 · AT1G24280)GLUCOSE-6-PHOSPHATE DEHYDROGENASE 3⌘
A. thalianaNCBI:NP_197829.1 · TAIR:locus:2152911 (K16H17.12 · AT5G24410 · K16H17_12)⌘
C. elegansWB:WBGene00013301 (Y57G11C.3) · UniProtKB:O18229⌘
C. elegansWB:WBGene00007108 (gspd-1 · B0035.5) · UniProtKB:Q27464⌘
C. elegansWB:WBGene00011399 (T03F6.3) · UniProtKB:Q9XVJ2 (GNPI_CAEEL · T03F6.3)Probable glucosamine-6-phosphate isomerase⌘⌘
D. rerioENSEMBL:ENSDARP00000088131
D. rerioENSEMBL:ENSDARP00000095604
D. rerioENSEMBL:ENSDARP00000001421
D. rerioENSEMBL:ENSDARP00000039222
D. rerioENSEMBL:ENSDARP00000094268
D. rerioUniProtKB:Q567X3 · ZFIN:ZDB-GENE-050417-417 (gnpda1)glucosamine-6-phosphate deaminase 1⌘
D. rerioZFIN:ZDB-GENE-040822-9 (6-phosphogluconolactonase · pgls) · UniProtKB:Q68EK1⌘
D. discoideumdictyBase:DDB_G0292898 (6-phosphogluconolactonase · pgl · PGLS) · UniProtKB:Q54CJ3⌘
D. discoideumUniProtKB:Q557D2 · dictyBase:DDB_G0273131 (G6PD · zwf · G6PDH · g6pd-1)glucose 6-phosphate-1-dehydrogenase⌘
D. discoideumUniProtKB:Q557D2 · dictyBase:DDB_G0273639 (g6pd-2 · G6PD · zwf · G6PDH)glucose 6-phosphate-1-dehydrogenase⌘
D. discoideumUniProtKB:Q54XK9 · dictyBase:DDB_G0278873 (nagB2 · GNPDA1 · gnpda1 · gniA)glucosamine-6-phosphate isomerase, glucosamine-6-phosphate deaminase⌘
D. discoideumUniProtKB:Q54M58 · dictyBase:DDB_G0286195 (GPI · nagB1)PIG-L family protein, glucosamine-6-phosphate isomerase, glucosamine-6-phosphate deaminase⌘
D. melanogasterFB:FBgn0030239 (CG17333) · UniProtKB:Q9VZ64⌘
D. melanogasterUniProtKB:P12646 · FB:FBgn0004057 (CG12529 · G6PDH · G6PD · G-6pd · G-6-PD · Zw · G-6PD · G-6-pdh · g6pd · G6pdh · G6pd · G6-pd · Zwischenferment · G6-PD)glucose-6-phosphate dehydrogenase · Glucose-6-phosphate DH · Glucose-6-phosphate dehydrogenase · glucose-6-phosphate 1dehydrogenase⌘
D. melanogasterFB:FBgn0031717 (Oscillin · CG6957) · UniProtKB:Q9VMP9⌘
D. melanogasterFB:FBgn0037147 (CG7140) · UniProtKB:Q9VNW4⌘
E. coliUniProtKB:P42912 · ECOLI:G7636-MONOMER (ECK3129 · agaI · AgaI · b3141 · yraG)predicted galactosamine-6-phosphate isomerase⌘
E. coliUniProtKB:P0AC53 · ECOLI:GLU6PDEHYDROG-MONOMER (ECK1853 · G6PDH · b1852 · zwf · Zwf · B1852 · GLU6PDEHYDROG)glucose-6-phosphate dehydrogenase · glucose 6-phosphate-1-dehydrogenase⌘
E. coliUniProtKB:P0A759 · ECOLI:GLUCOSAMINE-6-P-DEAMIN-MONOMER (glmD · b0678 · NagB · ECK0666 · nagB)⌘
E. coliUniProtKB:P31470 · ECOLI:EG11728-MONOMER (ECK3711 · YieK · b3718 · yieK)predicted 6-phosphogluconolactonase⌘
G. gallusNCBI:XP_425746 · ENTREZ:428188
G. gallusNCBI:XP_420726 · ENTREZ:422772
G. gallusUniProtKB:Q5ZJY1 (Q5ZJY1 · RCJMB04_14h20 · IPI00600301) · ENTREZ:430442⌘
G. gallusUniProtKB:Q5ZLA0 (IPI00572218 · Q5ZLA0 · RCJMB04_7a23) · ENTREZ:416341⌘
H. sapiensENSEMBL:ENSG00000130313 · UniProtKB:O95336 (6PGL_HUMAN · IPI00029997 · 6-phosphogluconolactonase · PGLS · O95336)⌘
H. sapiensENSEMBL:ENSG00000160211 · UniProtKB:P11413 (IPI00289800 · G6PD_HUMAN · G6PD · IPI00216008 · P11413)Glucose-6-phosphate 1-dehydrogenase⌘
H. sapiensENSEMBL:ENSG00000049239 · UniProtKB:O95479 (G6PE_HUMAN · GDH · H6PD · IPI00607861 · O95479)GDH/6PGL endoplasmic bifunctional protein⌘
H. sapiensENSEMBL:ENSG00000113552 · UniProtKB:P46926 (IPI00009305 · KIAA0060 · GNPI · GNPDA1 · GNPI1_HUMAN · P46926 · HLN)Glucosamine-6-phosphate isomerase 1⌘
H. sapiensENSEMBL:ENSG00000163281 · UniProtKB:Q8TDQ7 (Q8TDQ7 · IPI00550894 · GNPDA2 · GNPI2_HUMAN · IPI00896510 · IPI00896466)Glucosamine-6-phosphate isomerase 2⌘
M. musculusNCBI:XP_995500 · MGI:MGI:3647532
M. musculusMGI:MGI:1913421 (Pgls · 6-phosphogluconolactonase) · UniProtKB:Q9CQ60⌘
M. musculusUniProtKB:Q00612 · MGI:MGI:105979 (G6pd · G28A · Gpdx · G6pdx)glucose-6-phosphate dehydrogenase X-linked⌘
M. musculusUniProtKB:P97324 · MGI:MGI:105977 (Gpd2 · G6pd2 · G6pdx-ps1 · Gpd-2)glucose-6-phosphate dehydrogenase 2⌘
M. musculusUniProtKB:Q8CFX1 · MGI:MGI:2140356 (Gpd-1 · G6pd1 · H6pd · Gpd1)hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)⌘
M. musculusUniProtKB:O88958 · MGI:MGI:1347054 (Gnpi · Gnp1 · Gnpda1 · oscillin)glucose-6-phosphate isomerase · glucosamine-6-phosphate deaminase 1⌘
M. musculusUniProtKB:Q9CRC9 · MGI:MGI:1915230 (Gnp2 · Gnpda2)glucosamine-6-phosphate deaminase 2⌘
R. norvegicusNCBI:XP_001077409 · RGD:1305521 (Gnpda2)glucosamine-6-phosphate deaminase 2⌘
R. norvegicusNCBI:XP_001053009 · RGD:1596984
R. norvegicusNCBI:XP_001075788 · RGD:1306562 (H6pd)hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)⌘
R. norvegicusNCBI:XP_214296 · RGD:1307001 (Pgls · 6-phosphogluconolactonase)⌘
R. norvegicusNCBI:XP_001066558 · RGD:1585624 (Gnpda1)glucosamine-6-phosphate deaminase 1⌘
R. norvegicusUniProtKB:P05370 · RGD:2645 (G6pd)glucose-6-phosphate dehydrogenase⌘
S. cerevisiaeUniProtKB:P11412 · SGD:S000005185 (YNL241C · ZWF1 · POS10 · MET19)Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway⌘
S. cerevisiaeUniProtKB:P50278 · SGD:S000005317 (SOL1 · YNR034W)Protein with a possible role in tRNA export⌘
S. cerevisiaeUniProtKB:P37262 · SGD:S000000718 (YCRX13W · SOL2 · YCR073W-A)Protein with a possible role in tRNA export⌘
S. cerevisiaeUniProtKB:P38858 · SGD:S000001206 (SOL3 · YHR163W)6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway⌘
S. cerevisiaeUniProtKB:P53315 · SGD:S000003480 (SOL4 · YGR248W)6-phosphogluconolactonase with similarity to Sol3p⌘
S. pombeGeneDB_Spombe:SPCC16C4.10 (SPCC16C4.10 · 6-phosphogluconolactonase) · UniProtKB:O74455⌘
S. pombeUniProtKB:O59812 · GeneDB_Spombe:SPCC794.01c (SPCC794.01c)glucose-6-phosphate 1-dehydrogenase⌘
S. pombeUniProtKB:O14137 · GeneDB_Spombe:SPAC3C7.13c (SPAC3C7.13c)glucose-6-phosphate 1-dehydrogenase⌘
S. pombeUniProtKB:O00091 · GeneDB_Spombe:SPAC3A12.18 (zwf1 · SPAC9.01 · SPAC3A12.18)glucose-6-phosphate 1-dehydrogenase⌘
ProteinPublicationCurator Notes
UniProtKB:P11412 · SGD:S000005185PMID:16193512 Merritt J, et al. Parallel analysis of mutant human glucose 6-phosphate dehydrogenase in yeast using PCR colonies. Biotechnol Bioeng. 2005 Dec 5;92(5):519-31.The H. sapiens protein P11413 complements a homologous mutation in S. cerevisiae.
UniProtKB:P11412 · SGD:S000005185PMID:14757426 Grabowska D, et al. A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia--characterization of enzyme using yeast expression system and molecular modeling. Blood Cells Mol Dis. 2004 Jan-Feb;32(1):124-30.The H. sapiens protein P11413 complements a homologous mutation in S. cerevisiae.
UniProtKB:P11412 · SGD:S000005185PMID:14757426 Grabowska D, et al. A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia--characterization of enzyme using yeast expression system and molecular modeling. Blood Cells Mol Dis. 2004 Jan-Feb;32(1):124-30.The H. sapiens protein G6PD complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (2)
ENSEMBL:ENSG00000049239 · UniProtKB:O95479+305900 GLUCOSE-6-PHOSPHATE DEHYDROGENASE; G6PDANEMIA, NONSPHEROCYTIC HEMOLYTIC, DUE TO G6PD DEFICIENCY, INCLUDED
ENSEMBL:ENSG00000049239 · UniProtKB:O95479#604931 CORTISONE REDUCTASE DEFICIENCY;;11-@BETA-HYDROXYSTEROID DEHYDROGENASE, TYPE I, DEFICIENCY OF;;HSD11B1 DEFICIENCY
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