This family has 12 members: 6 Caenorhabditis elegans, 1 Danio rerio, 1 Drosophila melanogaster, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae.
Interactive Java Applets: Notung Tree Analysis · Jalview Alignment
| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| C. elegans | UniProtKB:Q18939 · WB:WBGene00008367 (D1053.2) |  | |
| C. elegans | WB:WBGene00010067 (F54F7.7) · UniProtKB:Q20794 | | |
| C. elegans | WB:WBGene00010120 (F55G7.2) · UniProtKB:Q20856 | | |
| C. elegans | WB:WBGene00012302 (W06D11.4) · UniProtKB:Q23200 | | |
| C. elegans | WB:WBGene00022512 (ZC53.6) · UniProtKB:Q23375 | | |
| C. elegans | WB:WBGene00021474 (Y39G10AR.18) · UniProtKB:Q6AW06 | | |
| D. rerio | ENSEMBL:ENSDARP00000083509 | ||
| D. melanogaster | FB:FBgn0014963 (l(3)03342 · anon-WO0118547.319 · CG10272 · l(3)sA3484 · gpp · Gpp · grappa · dDOT1L · BcDNA:SD05230 · grp) · UniProtKB:Q8INR6 | | |
| H. sapiens | ENSEMBL:ENSG00000104885 · UniProtKB:Q8TEK3 (IPI00289034 · DOT1L · DOT1L_HUMAN · IPI00873164 · KIAA1814 · Q8TEK3 · KMT4) | Histone-lysine N-methyltransferase, H3 lysine-79 specific | |
| M. musculus | NCBI:NP_955354 · MGI:MGI:2143886 (mDot1 · Dot1l · KMT4) | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | |
| R. norvegicus | NCBI:XP_343160 · RGD:1306644 (Dot1l) | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | |
| S. cerevisiae | UniProtKB:Q04089 · SGD:S000002848 (PCH1 · YDR440W · DOT1) | Nucleosomal histone H3-Lys79 methylase | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| SGD Disease Papers (1) | |
|---|---|
| UniProtKB:Q04089 · SGD:S000002848 |  15851025 Okada Y, et al. (2005) hDOT1L links histone methylation to leukemogenesis. Cell 121(2):167-78 |