P-POD: Princeton Protein Orthology Database: GO3/Jaccard2308

This family has 13 members: 1 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 1 Homo sapiens, 3 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

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GO3/Jaccard2308
13 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_568284.1 · TAIR:locus:2179827 (T19L5.10 · T19L5_10 · 5-FCL · AT5G13050)5-FORMYLTETRAHYDROFOLATE CYCLOLIGASE · 5-CHO-THF CYCLOLIGASE⌘
C. elegansWB:WBGene00013708 (Y106G6E.4) · UniProtKB:Q9XWE6⌘
D. rerioENSEMBL:ENSDARP00000062271
D. melanogasterFB:FBgn0034851 · UniProtKB:Q8MLS1
E. coliUniProtKB:P0AC28 · ECOLI:EG11158-MONOMER (b2912 · ECK2907 · YgfA · ygfA)predicted ligase⌘
G. gallusNCBI:XP_413857 · ENTREZ:415484
H. sapiensENSEMBL:ENSG00000136371 · UniProtKB:P49914 (MTHFS_HUMAN · IPI00220567 · MTHFS · P49914)5-formyltetrahydrofolate cyclo-ligase⌘
M. musculusMGI:MGI:3780550 · NCBI:NP_001122073
M. musculusNCBI:XP_001473392 · MGI:MGI:3780540
M. musculusUniProtKB:Q9D110 · MGI:MGI:1340032 (Mthfs)5, 10-methenyltetrahydrofolate synthetase⌘
R. norvegicusUniProtKB:Q5M9F6 · RGD:1306876 (Mthfs)5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)⌘
S. cerevisiaeUniProtKB:P40099 · SGD:S000000985 (FAU1 · YER183C)5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis⌘
S. pombeUniProtKB:Q9P7W2 · GeneDB_Spombe:SPBC1703.08c (SPBC1703.08c)5-formyltetrahydrofolate cyclo-ligase⌘
ProteinPublicationCurator Notes
UniProtKB:P40099 · SGD:S000000985PMID:12207015 Roje S, et al. Cloning and characterization of mitochondrial 5-formyltetrahydrofolate cycloligase from higher plants. J Biol Chem. 2002 Nov 8;277(45):42748-54.The A. thaliana protein AT5G13050.1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P40099 · SGD:S000000985PMID:11923304 Holmes WB, et al. Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae. J Biol Chem. 2002 Jun 7;277(23):20205-13.The S. cerevisiae protein FAU1 was expressed in E. coli, but complementation was not directly tested.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
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