This family has 76 members: 8 Arabidopsis thaliana, 5 Caenorhabditis elegans, 5 Danio rerio, 7 Dictyostelium discoideum, 6 Drosophila melanogaster, 1 Escherichia coli, 10 Gallus gallus, 8 Homo sapiens, 7 Mus musculus, 9 Rattus norvegicus, 5 Saccharomyces cerevisiae, 5 Schizosaccharomyces pombe.
Interactive Java Applets: Notung Tree Analysis · Jalview Alignment
| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | TAIR:locus:2059969 (AT2G42270 · T24P15.18 · T24P15_18) · NCBI:NP_181756.1 |  | |
| A. thaliana | NCBI:NP_001078482.1 · TAIR:locus:2125677 | ||
| A. thaliana | NCBI:NP_189410.2 · TAIR:locus:2089144 (RCK · ROCK-N-ROLLERS · MER3 · AT3G27730 · MGF10.13) | | |
| A. thaliana | NCBI:NP_565338.1 · TAIR:locus:2063648 (AT2G06990 · HEN2 · T4E14_10 · T4E14.10) | hua enhancer 2 | |
| A. thaliana | NCBI:NP_176185.1 · TAIR:locus:2026001 (AT1G59760 · F23H11_8 · F23H11.8) | | |
| A. thaliana | NCBI:NP_190280.2 · TAIR:locus:2075566 (F13I12.10 · AT3G46960) | | |
| A. thaliana | NCBI:NP_173520.1 · TAIR:locus:2037375 (F9H16_5 · emb1507 · F9H16.5 · AT1G20960) | embryo defective 1507 | |
| A. thaliana | NCBI:NP_200922.2 · TAIR:locus:2159451 (MAF19.14 · AT5G61140 · MAF19_14) | | |
| C. elegans | WB:WBGene00012896 (Y46G5A.4) · UniProtKB:Q9U2G0 (Y46G5A.4 · U520_CAEEL) | Putative U5 small nuclear ribonucleoprotein 200 kDa helicase | |
| C. elegans | WB:WBGene00012342 (mtr-4 · W08D2.7) · UniProtKB:Q23223 | | |
| C. elegans | WB:WBGene00020964 (polq-1 · W03A3.2) · UniProtKB:A0FLQ6 | | |
| C. elegans | WB:WBGene00008502 (F01G4.3) · UniProtKB:Q19103 | | |
| C. elegans | WB:WBGene00021905 (hel-308 · Y55B1AL.3) · UniProtKB:Q9N389 | | |
| D. rerio | ENSEMBL:ENSDARP00000024380 | ||
| D. rerio | ENSEMBL:ENSDARG00000068922 · UniProtKB:A2BIH3 | ||
| D. rerio | UniProtKB:Q1LVP8 · ZFIN:ZDB-GENE-060503-421 (helq) | helicase, POLQ-like | |
| D. rerio | UniProtKB:Q1LWQ1 · ZFIN:ZDB-GENE-010430-5 (skiv2l) | superkiller viralicidic activity 2 (S. cerevisiae homolog)-like | |
| D. rerio | ZFIN:ZDB-GENE-040724-232 (si:rp71-1p14.5) · UniProtKB:Q6ZM94 | | |
| D. discoideum | UniProtKB:Q54G57 · dictyBase:DDB_G0290389 (ascc3) | activating signal cointegrator 1 complex subunit, DEAD/DEAH box helicase, Sec63 domain-containing protein | |
| D. discoideum | dictyBase:DDB_G0279107 (DDB_G0279107) · UniProtKB:Q54X98 | | |
| D. discoideum | UniProtKB:Q55CI8 · dictyBase:DDB_G0270042 (ascc3l) | DEAD/DEAH box helicase, U5 small nuclear ribonucleoprotein 200 kDa helicase, Sec63 domain-containing protein | |
| D. discoideum | UniProtKB:Q86HT8 · dictyBase:DDB_G0274421 (DDB_G0274421) | Similar to Thermotoga maritima. DNA-directed DNA polymerase I. | |
| D. discoideum | UniProtKB:Q86IE2 · dictyBase:DDB_G0275633 (DDB_G0275633) | superkiller viralicidic activity 2-like protein, DEAD/DEAH box helicase | |
| D. discoideum | UniProtKB:Q86K90 · dictyBase:DDB_G0277211 (DDB_G0277211) | superkiller viralicidic activity 2-like protein, DEAD/DEAH box helicase | |
| D. discoideum | UniProtKB:Q86KS9 · dictyBase:DDB_G0277751 (DDB_G0277751) | Similar to Mus musculus (Mouse). DNA polymerase theta short isoform. | |
| D. melanogaster | UniProtKB:Q9VUV9 · FB:FBgn0036548 (Brr2 · cg5931 · anon-EST:Liang-1.21 · CG5931) | clone 1.21 | |
| D. melanogaster | UniProtKB:Q5BI65 · FB:FBgn0002905 (Mus308 · CG6019 · Nuclease-3 · AAF54858 · mus308 · 0443/09 · Nuc3 · mus-308) | Pol theta · mutagen-sensitive 308 | |
| D. melanogaster | FB:FBgn0039117 (cg10210 · CG10210 · Ski2/tst · twister · SKI2 · Ski2 · tst) · UniProtKB:Q9VCH8 | | |
| D. melanogaster | FB:FBgn0038344 (CG5205 · cg5205) · UniProtKB:Q9VF56 | | |
| D. melanogaster | UniProtKB:Q9VSE2 · FB:FBgn0002899 (mus(3)301 · hel308 · anon-WO0118547.354 · spindle-C · CG7972 · SpnC · spn-C · spindel · spnC · mus301 · cg7972) | mutagen-sensitive 301 · spindle C | |
| D. melanogaster | UniProtKB:Q9Y134 · FB:FBgn0001986 (CG4152 · br44 · l(2)k14422 · cg4152 · l.2.35Df · BG:DS09217.2 · BcDNA:GH07290 · l(2)br44 · l(2)k14423 · l(2)35Df) | lethal (2) 35Df | |
| E. coli | UniProtKB:P00582 · ECOLI:EG10746-MONOMER (ECK3855 · polA · resA · b3863 · PolA) | DNA polymerase I, 3' --> 5' polymerase, 5' --> 3' and 3' --> 5' exonuclease | |
| G. gallus | NCBI:XP_419816 · ENTREZ:421790 | ||
| G. gallus | NCBI:XP_420565 · ENTREZ:422606 | ||
| G. gallus | NCBI:XP_428333 · ENTREZ:430782 | ||
| G. gallus | NCBI:XP_422924 · ENTREZ:425133 | ||
| G. gallus | NCBI:XP_428264 · ENTREZ:430713 | ||
| G. gallus | NCBI:XP_001233526 · ENTREZ:770195 | ||
| G. gallus | NCBI:XP_416549 · ENTREZ:418326 | ||
| G. gallus | NCBI:XP_420834 · ENTREZ:422892 | ||
| G. gallus | UniProtKB:Q5F463 (IPI00574020 · Q5F463 · RCJMB04_2m11) · ENTREZ:503574 | | |
| G. gallus | UniProtKB:Q5ZMQ1 (IPI00599020 · RCJMB04_1h14 · Q5ZMQ1) · ENTREZ:427137 | | |
| H. sapiens | ENSEMBL:ENSG00000130997 · UniProtKB:Q7Z5Q5 (POLN · IPI00737463 · IPI00385298 · DPOLN_HUMAN · Q7Z5Q5) | DNA polymerase nu | |
| H. sapiens | ENSEMBL:ENSG00000051341 · UniProtKB:O75417 (O75417 · IPI00794779 · POLH · DPOLQ_HUMAN · POLQ) | DNA polymerase theta | |
| H. sapiens | ENSEMBL:ENSG00000112249 · UniProtKB:Q8N3C0 (IPI00430472 · HELIC1 · ASCC3 · HELC1_HUMAN · Q8N3C0) | Activating signal cointegrator 1 complex subunit 3 | |
| H. sapiens | ENSEMBL:ENSG00000162669 · UniProtKB:A2PYH4 (IPI00852603 · A2PYH4 · HFM1 · HFM1_HUMAN · IPI00374013 · SEC3D1) | Probable ATP-dependent DNA helicase HFM1 | |
| H. sapiens | ENSEMBL:ENSG00000163312 · UniProtKB:Q8TDG4 (HEL308 · IPI00152527 · IPI00889496 · IPI00647582 · Q8TDG4 · IPI00807650 · HL308_HUMAN · IPI00889766) | ATP-dependent DNA helicase HEL308 | |
| H. sapiens | ENSEMBL:ENSG00000039123 · UniProtKB:P42285 (SKIV2L2 · SK2L2_HUMAN · P42285 · KIAA0052 · IPI00647217) | Superkiller viralicidic activity 2-like 2 | |
| H. sapiens | ENSEMBL:ENSG00000206353 · UniProtKB:Q15477 (DDX13 · SKIV2 · W · SKI2W · SKIV2_HUMAN · IPI00414819 · SKIV2L · Q15477) | Helicase SKI2W | |
| H. sapiens | ENSEMBL:ENSG00000144028 · UniProtKB:O75643 (U520_HUMAN · SNRNP200 · HELIC2 · ASCC3L1 · O75643 · IPI00168235 · KIAA0788 · IPI00420014) | U5 small nuclear ribonucleoprotein 200 kDa helicase | |
| M. musculus | NCBI:NP_084253 · MGI:MGI:2155399 (Polq) | polymerase (DNA directed), theta | |
| M. musculus | NCBI:NP_796188 · MGI:MGI:2444401 (Snrnp200 · U5-200KD · HELIC2 · Ascc3l1) | small nuclear ribonucleoprotein 200 (U5) | |
| M. musculus | NCBI:NP_067312 · MGI:MGI:1099835 (Skiv2l · Ski2w) | superkiller viralicidic activity 2-like (S. cerevisiae) | |
| M. musculus | UniProtKB:Q7TQ07 · MGI:MGI:2675617 (Poln · POL4P) | DNA polymerase N | |
| M. musculus | UniProtKB:Q2VPA6 · MGI:MGI:2176740 (Hel308 · Helq) | helicase, POLQ-like | |
| M. musculus | UniProtKB:Q9CZU3 · MGI:MGI:1919448 (Skiv2l2) | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | |
| M. musculus | UniProtKB:Q6PB36 · MGI:MGI:1925237 (Helic1 · Ascc3 · ASC1p200) | activating signal cointegrator 1 complex subunit 3 | |
| R. norvegicus | NCBI:XP_573637 · RGD:1560044 | ||
| R. norvegicus | NCBI:XP_228345 · RGD:1307995 (Ascc3) | activating signal cointegrator 1 complex subunit 3 | |
| R. norvegicus | NCBI:XP_001062278 · RGD:1309795 (Polq) | polymerase (DNA directed), theta | |
| R. norvegicus | NCBI:XP_001070139 · RGD:1591429 | ||
| R. norvegicus | NCBI:XP_573636 · RGD:1593173 (Poln) | polymerase (DNA directed) nu | |
| R. norvegicus | NCBI:XP_214002 · RGD:1588599 | ||
| R. norvegicus | UniProtKB:Q499Q9 · RGD:1305984 (Skiv2l2) | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | |
| R. norvegicus | RGD:1561120 · UniProtKB:Q4KLH1 | ||
| R. norvegicus | UniProtKB:Q6MG76 · RGD:1303059 (Skiv2l) | superkiller viralicidic activity 2-like (S. cerevisiae ) | |
| S. cerevisiae | UniProtKB:P32639 · SGD:S000000974 (YER172C · BRR2 · SLT22 · PRP44 · SNU246 · RSS1) | RNA-dependent ATPase RNA helicase (DEIH box) | |
| S. cerevisiae | UniProtKB:P51979 · SGD:S000003220 (YGL251C · MER3 · HFM1) | Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control | |
| S. cerevisiae | UniProtKB:P47047 · SGD:S000003586 (YJL050W · DOB1 · MTR4) | ATP-dependent 3'-5' RNA helicase, involved in nuclear RNA quality control both as a component of the TRAMP complex and in TRAMP independent processes | |
| S. cerevisiae | UniProtKB:P35207 · SGD:S000004390 (YLR398C · SKI2) | Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic exosome | |
| S. cerevisiae | UniProtKB:P53327 · SGD:S000003503 (YGR271W · SLH1) | Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs | |
| S. pombe | UniProtKB:Q9UT24 · GeneDB_Spombe:SPAC9.03c (spp41 · brr2 · SPAC9.03c) | U5 snRNP complex subunit Brr2 | |
| S. pombe | UniProtKB:O60072 · GeneDB_Spombe:SPBC13G1.10c (SPBC13G1.10c · mug81) | ATP-dependent RNA helicase Slh1 | |
| S. pombe | UniProtKB:O14232 · GeneDB_Spombe:SPAC6F12.16c (mtr4 · SPAC6F12.16c) | ATP-dependent RNA helicase, TRAMP complex subunit Mtr4 | |
| S. pombe | UniProtKB:O13799 · GeneDB_Spombe:SPAC17H9.02 (SPAC17H9.02) | TRAMP complex ATP-dependent RNA helicase | |
| S. pombe | UniProtKB:O59801 · GeneDB_Spombe:SPCC550.03c (SPCC550.03c) | Ski complex RNA helicase Ski2 | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |