P-POD: Princeton Protein Orthology Database: GO3/Jaccard22

This family has 427 members: 62 Arabidopsis thaliana, 41 Caenorhabditis elegans, 36 Danio rerio, 31 Dictyostelium discoideum, 33 Drosophila melanogaster, 6 Escherichia coli, 33 Gallus gallus, 44 Homo sapiens, 46 Mus musculus, 44 Rattus norvegicus, 27 Saccharomyces cerevisiae, 24 Schizosaccharomyces pombe.

• Protein Family
• Functional Conservation (12)
• Download Files (5)
• Disease References (49)

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

427 members.

Organism	Protein (Synonyms)	Description	AmiGO
A. thaliana	NCBI:NP_187225.2 · TAIR:locus:2074429 (AT3G05740 · RECQI1 · F18C1.21)	Arabidopsis RecQ helicase l1
A. thaliana	NCBI:NP_181780.1 · TAIR:locus:2041549 (AT2G42520 · F14N22.21 · F14N22_21)
A. thaliana	NCBI:NP_180929.1 · TAIR:locus:2057640 (AT2G33730 · T1B8_4 · T1B8.4)
A. thaliana	NCBI:NP_199941.1 · TAIR:locus:2176192 (AT5G51280 · MWD22.23 · MWD22_23)
A. thaliana	NCBI:NP_195063.1 · TAIR:locus:2119176 (F17M5.130 · F17M5_130 · AT4G33370)
A. thaliana	NCBI:NP_001031943.1 · TAIR:locus:504955106 (AT5G26742 · emb1138)	embryo defective 1138
A. thaliana	NCBI:NP_187583.2 · TAIR:locus:2075034 (F11F8.31 · AT3G09720)
A. thaliana	NCBI:NP_173516.1 · TAIR:locus:2037416 (F9H16.10 · AT1G20920 · F9H16_10)
A. thaliana	NCBI:NP_188307.3 · TAIR:locus:2086775 (AT3G16840 · K20I9.7)
A. thaliana	NCBI:NP_200302.1 · TAIR:locus:2160225 (MBG8_18 · AT5G54910 · MBG8.18)
A. thaliana	NCBI:NP_172562.2 · TAIR:locus:2197394 (ATSGS1 · ATRECQ4A · T19D16.15 · T19D16_15 · RECQ4A · AT1G10930)
A. thaliana	NCBI:NP_188610.1 · TAIR:locus:2091191 (AT3G19760 · MMB12.4)
A. thaliana	NCBI:NP_172737.2 · TAIR:locus:2010306 (T12C24.30 · EMB1586 · AT1G12770)	embryo defective 1586
A. thaliana	NCBI:NP_201391.1 · TAIR:locus:2152099 (AT5G65900 · K14B20_7 · K14B20.7)
A. thaliana	NCBI:NP_175911.1 · TAIR:locus:2035741 (AT1G55150 · T7N22.9 · T7N22_9)
A. thaliana	NCBI:NP_193320.3 · TAIR:locus:2130839 (DL3965W · AT4G15850 · FCAALL.401 · ATRH1)
A. thaliana	NCBI:NP_191416.1 · TAIR:locus:2076436 (AT3G58570 · F14P22.160)
A. thaliana	NCBI:NP_177284.1 · TAIR:locus:2032338 (F3I17_7 · F3I17.7 · AT1G71280)
A. thaliana	NCBI:NP_175829.1 · TAIR:locus:2020078 (AT1G54270 · F20D21.9 · EIF4A-2 · F20D21_9)
A. thaliana	NCBI:NP_568499.1 · TAIR:locus:2180255 (T1G16_10 · T1G16.10 · RECQSIM · AT5G27680)	Arabidopsis RecQ helicase sim
A. thaliana	NCBI:NP_191683.1 · TAIR:locus:2098886 (AT3G61240 · T20K12.140)
A. thaliana	NCBI:NP_196164.1 · TAIR:locus:2153564 (K18I23_26 · K18I23.26 · AT5G05450)
A. thaliana	NCBI:NP_176289.3 · TAIR:locus:2206031 (T7P1.7 · ATRECQ4B · RECQL4B · T7P1_7 · AT1G60930)	RECQ HELICASE L4B · ARABIDOPSIS RECQ HELICASE L4B
A. thaliana	NCBI:NP_187299.1 · TAIR:locus:2081061 (F24P17_2 · AT3G06480 · F24P17.2)
A. thaliana	NCBI:NP_191975.2 · TAIR:locus:2127043 (AT4G00660 · F6N23_6 · F6N23.6)
A. thaliana	NCBI:NP_176514.1 · TAIR:locus:2038431 (F9N12_13 · F9N12.13 · AT1G63250)
A. thaliana	NCBI:NP_187354.1 · TAIR:locus:2077592 (AT3G06980 · F17A9.13)
A. thaliana	NCBI:NP_974812.1 · TAIR:locus:2182202 (T24G5_110 · T24G5.110 · AT5G19210)
A. thaliana	NCBI:NP_974985.1 · TAIR:locus:2162022 (MDC12.8 · MDC12_8 · AT5G63120)
A. thaliana	NCBI:NP_001030693.1 · TAIR:locus:2088237 (TIF4A1 · EIF4A1 · MDC16.5 · RH4 · AT3G13920)	EUKARYOTIC TRANSLATION INITIATION FACTOR 4A1
A. thaliana	NCBI:NP_188870.1 · TAIR:locus:2087832 (AT3G22310 · PMH1 · ATRH9 · MCB17.17)	RNA HELICASE 9 · PUTATIVE MITOCHONDRIAL RNA HELICASE 1
A. thaliana	NCBI:NP_177293.1 · TAIR:locus:2825324 (AT1G71370 · F3I17_18 · F3I17.18)
A. thaliana	NCBI:NP_850492.1 · TAIR:locus:2084178 (AT3G01540 · F4P13_9 · DRH1 · F4P13.9 · ATDRH1)	RNA HELICASE DRH1 · ARABIDOPSIS THALIANA DEAD BOX RNA HELICASE 1 · DEAD BOX RNA HELICASE 1
A. thaliana	NCBI:NP_178818.1 · TAIR:locus:2054688 (T12J2.7 · AT2G07750 · T12J2_7)
A. thaliana	NCBI:NP_196479.1 · TAIR:locus:2159527 (MAH20_18 · STRS2 · AT5G08620 · ATRH25 · MAH20.18)	RNA HELICASE 25 · STRESS RESPONSE SUPPRESSOR 2
A. thaliana	NCBI:NP_187573.1 · TAIR:locus:2074899 (AT3G09620 · F11F8.21)
A. thaliana	NCBI:NP_568931.1 · TAIR:locus:2173517 (MSL3.110 · MSL3_110 · AT5G60990)
A. thaliana	NCBI:NP_176207.1 · TAIR:locus:2202730 (T2K10_4 · T2K10.4 · AT1G59990)
A. thaliana	NCBI:NP_181602.1 · TAIR:locus:2064844 (T7D17_12 · T7D17.12 · AT2G40700)
A. thaliana	NCBI:NP_196478.2 · TAIR:locus:2159517 (MAH20_17 · MAH20.17 · AT5G08610)
A. thaliana	NCBI:NP_188872.2 · TAIR:locus:2087852 (MCB17.21 · AT3G22330 · PMH2)	putative mitochondrial RNA helicase 2
A. thaliana	NCBI:NP_195217.1 · TAIR:locus:2116920 (F11I11_150 · F11I11.150 · AT4G34910)
A. thaliana	NCBI:NP_849348.1 · TAIR:locus:2118509 (AT4G09730 · F17A8_80 · F17A8.80)
A. thaliana	NCBI:NP_190879.1 · TAIR:locus:2101993 (T4D2.40 · LOS4 · AT3G53110)	LOW EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 4
A. thaliana	NCBI:NP_182105.1 · TAIR:locus:2050715 (F4I18.21 · AT2G45810)
A. thaliana	NCBI:NP_174421.2 · TAIR:locus:2197555 (T19E23_16 · RECQL2 · ATRECQ2 · T19E23.16 · AT1G31360)	ARABIDOPSIS THALIANA RECQ 2 · ARABIDOPSIS RECQ HELICASE L2
A. thaliana	NCBI:NP_188490.1 · TAIR:locus:2086909 (K24M9.9 · AT3G18600)
A. thaliana	NCBI:NP_175549.1 · TAIR:locus:2008296 (F11M15_24 · AT1G51380 · F11M15.24)
A. thaliana	NCBI:NP_201025.1 · TAIR:locus:2167903 (MMI9_2 · AT5G62190 · PRH75 · MMI9.2)	RNA Helicase
A. thaliana	NCBI:NP_568244.2 · TAIR:locus:2147987 (F2I11_60 · F2I11.60 · AT5G11170)
A. thaliana	NCBI:NP_201168.1 · TAIR:locus:2160639 (AT5G63630 · MBK5.11 · MBK5_11)
A. thaliana	NCBI:NP_974208.1 · TAIR:locus:2828586 (AT3G02065 · F1C9.15)
A. thaliana	NCBI:NP_174479.1 · TAIR:locus:2034481 (AT1G31970 · STRS1 · F5M6.3)	STRESS RESPONSE SUPPRESSOR 1
A. thaliana	NCBI:NP_195299.2 · TAIR:locus:2127998 (RecQl3 · F8D20.250 · F8D20_250 · AT4G35740)
A. thaliana	NCBI:NP_196965.2 · TAIR:locus:2222617 (AT5G14610 · T15N1_100 · T15N1.100)
A. thaliana	NCBI:NP_566099.1 · TAIR:locus:2065215 (T8I13.17 · AT2G47330)
A. thaliana	NCBI:NP_567067.1 · TAIR:locus:2076351 (F14P22.100 · AT3G58510)
A. thaliana	NCBI:NP_193396.3 · TAIR:locus:2130918 (AT4G16630 · DL4340C · FCAALL.424)
A. thaliana	NCBI:NP_177417.1 · TAIR:locus:2030285 (AT1G72730 · F28P22_8 · F28P22.8)
A. thaliana	NCBI:NP_568245.1 · TAIR:locus:2148027 (F2I11_90 · F2I11.90 · AT5G11200)
A. thaliana	NCBI:NP_177830.1 · TAIR:locus:2025267
A. thaliana	NCBI:NP_173078.1 · TAIR:locus:2032910 (F3O9_8 · AT1G16280 · F3O9.8)
C. elegans	WB:WBGene00001865 (him-6 · T04A11.6) · UniProtKB:O18017
C. elegans	WB:WBGene00000479 (cgh-1 · C07H6.5) · UniProtKB:Q95YF3 (cgh-1 · C07H6.5 · CGH1_CAEEL)	ATP-dependent RNA helicase cgh-1
C. elegans	WB:WBGene00012059 (T26G10.1) · UniProtKB:P34580
C. elegans	WB:WBGene00013983 (ZK512.2) · UniProtKB:P34640
C. elegans	WB:WBGene00001598 (glh-1 · T21G5.3) · UniProtKB:P34689 (glh-1 · GLH1_CAEEL · T21G5.3)	ATP-dependent RNA helicase glh-1
C. elegans	WB:WBGene00001599 (C55B7.1 · glh-2) · UniProtKB:Q966L9 (C55B7.1 · GLH2_CAEEL · glh-2)	ATP-dependent RNA helicase glh-2
C. elegans	WB:WBGene00001600 (B0414.6 · glh-3) · UniProtKB:O01836 (B0414.6 · glh-3 · GLH3_CAEEL)	ATP-dependent RNA helicase glh-3
C. elegans	WB:WBGene00001601 (T12F5.3 · glh-4) · UniProtKB:O76743 (T12F5.3 · GLH4_CAEEL · glh-4)	ATP-dependent RNA helicase glh-4
C. elegans	WB:WBGene00002083 (inf-1 · F57B9.6) · UniProtKB:P27639
C. elegans	UniProtKB:P46064 · WB:WBGene00006430
C. elegans	WB:WBGene00001840 (hel-1 · C26D10.2) · UniProtKB:Q18212
C. elegans	WB:WBGene00006944 (F18C5.2 · wrn-1) · UniProtKB:Q19546
C. elegans	WB:WBGene00022792 (ZK686.2) · UniProtKB:P34668
C. elegans	WB:WBGene00020284 (T06A10.1 · mel-46) · UniProtKB:A3QMD4
C. elegans	WB:WBGene00016073 (C24H12.4) · UniProtKB:O17157
C. elegans	WB:WBGene00018007 (F33D11.10) · UniProtKB:O44781
C. elegans	WB:WBGene00015232 (B0511.6) · UniProtKB:O61815
C. elegans	WB:WBGene00010280 (F58G11.2) · UniProtKB:P90897
C. elegans	WB:WBGene00018890 (F55F8.2) · UniProtKB:P91340
C. elegans	WB:WBGene00003507 (mut-14 · C14C11.6) · UniProtKB:Q17978
C. elegans	WB:WBGene00004322 (E03A3.2 · rcq-5) · UniProtKB:Q19046
C. elegans	WB:WBGene00018997 (F57B9.3) · UniProtKB:Q20935
C. elegans	WB:WBGene00011032 (R05D11.4) · UniProtKB:Q21736
C. elegans	WB:WBGene00011580 (ddx-19 · T07D4.4) · UniProtKB:Q22308
C. elegans	WB:WBGene00022587 (ZC317.1) · UniProtKB:Q23080
C. elegans	WB:WBGene00019219 (H20J04.4) · UniProtKB:Q2WF63
C. elegans	WB:WBGene00022184 (Y71H2AM.19) · UniProtKB:Q4W5R4
C. elegans	WB:WBGene00006888 (Y54E10A.9 · vbh-1) · UniProtKB:Q65XX1
C. elegans	WB:WBGene00022378 (Y94H6A.5) · UniProtKB:Q688Z4
C. elegans	WB:WBGene00008119 (C46F11.4) · UniProtKB:Q93382
C. elegans	WB:WBGene00017162 (ddx-23 · F01F1.7) · UniProtKB:Q95QN2
C. elegans	WB:WBGene00022148 (Y71G12B.8) · UniProtKB:Q95XM9
C. elegans	WB:WBGene00018776 (F53H1.1) · UniProtKB:Q965K2
C. elegans	WB:WBGene00022029 (Y65B4A.6) · UniProtKB:Q9BL61
C. elegans	WB:WBGene00021938 (Y55F3BR.1) · UniProtKB:Q9N341
C. elegans	WB:WBGene00021277 (Y23H5B.6) · UniProtKB:Q9N478
C. elegans	WB:WBGene00019245 (H27M09.1) · UniProtKB:Q9N5K1
C. elegans	WB:WBGene00019334 (K02F3.12) · UniProtKB:Q9TXJ8
C. elegans	WB:WBGene00021391 (Y38A10A.6) · UniProtKB:Q9UAX9
C. elegans	WB:WBGene00010260 (F58E10.3) · UniProtKB:Q9XUW5
C. elegans	WB:WBGene00013214 (Y54G11A.3) · UniProtKB:Q9XVZ6
D. rerio	ENSEMBL:ENSDARP00000077321
D. rerio	ENSEMBL:ENSDARP00000069472
D. rerio	ENSEMBL:ENSDARP00000065642
D. rerio	ENSEMBL:ENSDARP00000081816
D. rerio	ENSEMBL:ENSDARP00000087581
D. rerio	ENSEMBL:ENSDARP00000044651
D. rerio	ENSEMBL:ENSDARP00000081471
D. rerio	ENSEMBL:ENSDARP00000093660
D. rerio	ENSEMBL:ENSDARP00000091998
D. rerio	UniProtKB:Q6DRI7 · ZFIN:ZDB-GENE-040927-28 (ddx51)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
D. rerio	UniProtKB:Q8JHJ2 · ZFIN:ZDB-GENE-021212-1 (ddx55)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
D. rerio	ENSEMBL:ENSDARG00000010873 · UniProtKB:A4QN44
D. rerio	UniProtKB:O42107 · ZFIN:ZDB-GENE-990415-272 (vasa)	vasa homolog
D. rerio	ZFIN:ZDB-GENE-061013-64 (zgc:153386) · UniProtKB:Q08BL1
D. rerio	ENSEMBL:ENSDARG00000061865 · UniProtKB:Q0P3W4
D. rerio	UniProtKB:Q5RHI1 · ZFIN:ZDB-GENE-050809-134 (recql)	RecQ protein-like (DNA helicase Q1-like)
D. rerio	UniProtKB:Q5RIZ5 · ZFIN:ZDB-GENE-041001-215 (ddx1)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
D. rerio	UniProtKB:Q6DRL1 · ZFIN:ZDB-GENE-030131-9685 (ddx18)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
D. rerio	UniProtKB:Q6DRN0 · ZFIN:ZDB-GENE-031001-8 (ddx27)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
D. rerio	UniProtKB:Q6IQA5 · ZFIN:ZDB-GENE-030131-4275 (ddx39a)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39a
D. rerio	UniProtKB:Q6P9Z2 · ZFIN:ZDB-GENE-030131-6215 (ddx23)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
D. rerio	ZFIN:ZDB-GENE-980526-150 (pl10) · UniProtKB:Q6PBB2
D. rerio	UniProtKB:Q6TNU9 · ZFIN:ZDB-GENE-030131-925 (ddx5)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
D. rerio	UniProtKB:Q7SXU7 · ZFIN:ZDB-GENE-040426-1259 (bat1)	HLA-B associated transcript 1
D. rerio	UniProtKB:Q7ZVA6 · ZFIN:ZDB-GENE-040426-915 (eif4a3)	eukaryotic translation initiation factor 4A, isoform 3
D. rerio	UniProtKB:Q802C9 · ZFIN:ZDB-GENE-031030-2 (eif4a1a)	eukaryotic translation initiation factor 4A, isoform 1A
D. rerio	UniProtKB:Q803W0 · ZFIN:ZDB-GENE-040426-2902 (ddx39b)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b
D. rerio	UniProtKB:Q8JGR1 · ZFIN:ZDB-GENE-020419-30 (ddx19)	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
D. rerio	UniProtKB:Q8JGR2 · ZFIN:ZDB-GENE-021220-2 (ddx54)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
D. rerio	UniProtKB:A4QNU1 · ZFIN:ZDB-GENE-050208-665 (ddx59)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
D. rerio	UniProtKB:A5WVT8 · ZFIN:ZDB-GENE-040426-2802 (eif4a2)	eukaryotic translation initiation factor 4A, isoform 2
D. rerio	UniProtKB:A8E590 · ZFIN:ZDB-GENE-040120-6 (eif4a1b)	eukaryotic translation initiation factor 4A, isoform 1B
D. rerio	UniProtKB:B0S6P6 · ZFIN:ZDB-GENE-030131-1565 (ddx3)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3
D. rerio	UniProtKB:Q6DRE7 · ZFIN:ZDB-GENE-040825-3 (ddx56)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
D. rerio	ZFIN:ZDB-GENE-030131-3973 (si:ch211-89p1.3) · UniProtKB:Q6PH31
D. rerio	UniProtKB:Q7ZUT9 · ZFIN:ZDB-GENE-031030-3 (ddx49)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
D. discoideum	NCBI:EAL71344.2 · dictyBase:DDB_G0272384 (DDB_G0272384)	Bloom syndrome-like protein, ATP-dependent DNA helicase RecQ family protein
D. discoideum	NCBI:EDR41122.1 · dictyBase:DDB_G0268512 (wrn)	Werner syndrome protein, ATP-dependent DNA helicase RecQ family protein
D. discoideum	UniProtKB:Q54Q94 · dictyBase:DDB_G0284017 (ddx10)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54CE0 · dictyBase:DDB_G0293168 (ddx17)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54S03 · dictyBase:DDB_G0282741 (ddx18)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54TF8 · dictyBase:DDB_G0281553 (ddx19 · helC)	DEAD-box RNA helicase
D. discoideum	UniProtKB:Q55CP6 · dictyBase:DDB_G0269966 (ddx1)	putative RNA helicase, SPla/RYanodine receptor SPRY domain-containing protein, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54Y81 · dictyBase:DDB_G0277857 (Hel2B · ddx23 · prp28 · helB2)	putative RNA helicase, putative U5 small nuclear ribonucleoprotein, DEAD/DEAH box helicase, putative RNA splicing factor
D. discoideum	UniProtKB:Q54TD7 · dictyBase:DDB_G0281841 (ddx24)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54TJ4 · dictyBase:DDB_G0281711 (ddx27)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q869P0 · dictyBase:DDB_G0271708 (ddx31)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54QS3 · dictyBase:DDB_G0283661 (ddx3)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54KG1 · dictyBase:DDB_G0287361 (ddx41)	DEAD box protein abstrakt, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54IV3 · dictyBase:DDB_G0288501 (ddx42)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q553B1 · dictyBase:DDB_G0275443 (Hel2A · helB1 · prp5 · ddx46)	putative RNA helicase, DEAD/DEAH box helicase, putative RNA splicing factor
D. discoideum	UniProtKB:Q54VT4 · dictyBase:DDB_G0280147 (ddx47)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q55BR9 · dictyBase:DDB_G0270396 (ddx49)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54BD6 · dictyBase:DDB_G0293740 (ddx51)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q86IZ9 · dictyBase:DDB_G0274325 (ddx52)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54CD8 · dictyBase:DDB_G0292992 (ddx54 · helA · Hel1)	putative RNA helicase
D. discoideum	UniProtKB:Q54EC2 · dictyBase:DDB_G0291588 (ddx55)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54VF1 · dictyBase:DDB_G0280407 (ddx56)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q54E49 · dictyBase:DDB_G0291804 (ddx6)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q55D61 · dictyBase:DDB_G0269192 (eIF4AIII · tifA)	DEAD/DEAH box helicase domain-containing protein, eukaryotic translation initiation factor 4A
D. discoideum	UniProtKB:P90529 · dictyBase:DDB_G0269146 (ifdA)	DEAD/DEAH box helicase domain-containing protein, eukaryotic translation initiation factor 4A
D. discoideum	UniProtKB:Q54CB8 · dictyBase:DDB_G0293064 (DDB_G0293064)	CG10777 protein (LD32873P).
D. discoideum	UniProtKB:Q54DM3 · dictyBase:DDB_G0292130 (blm)	Bloom syndrome protein, ATP-dependent DNA helicase RecQ family protein
D. discoideum	dictyBase:DDB_G0292108 (DDB_G0292108) · UniProtKB:Q54DN9
D. discoideum	dictyBase:DDB_G0292010 (DDB_G0292010) · UniProtKB:Q54DV7
D. discoideum	UniProtKB:Q54T87 · dictyBase:DDB_G0281925 (DDB_G0281925)	putative RNA helicase, DEAD/DEAH box helicase
D. discoideum	UniProtKB:Q55CR6 · dictyBase:DDB_G0269932 (uap56)	ATP-dependent RNA helicase, DEAD/DEAH box helicase, putative RNA splicing factor
D. melanogaster	UniProtKB:Q9VGI8 · FB:FBgn0002906 (RecQ · DmBlm · mus309 · Dmblm · DmBLM · Blm · gesta1 · mus309/DmBLM · bloom · blm · RecQ-like · MUS309 · DmKu70 · CG6920)	mus 309 · genome stabilizer 1 · Bloom helicase · Drosophila Blm · Bloom's helicase · mutagen-sensitive 309
D. melanogaster	UniProtKB:P19109 · FB:FBgn0003261 (l(3)j3D5 · Dmp68 · DmRH8 · RM62 · CG10279 · p68 · l(3)j3D2 · Rm62 · 4136 · Lip · l(3)s5196 · Lighten-up · dmP68 · l(3)01086 · l(3)rG338)	Lighten up
D. melanogaster	FB:FBgn0025140 (PIT · pitchoune · pit · DmRH15 · CG6375) · UniProtKB:Q9VD51
D. melanogaster	UniProtKB:O61305 · FB:FBgn0024804 (Hel40 · DmDbp80 · hel-40 · Dbp80 · BcDNA:RE44177 · HEL80 · Hel80 · CG17023 · DBP80)	Dead box protein 80 · Helicase 80 · Helicase 40
D. melanogaster	FB:FBgn0015075 (DmRH12 · DDX1 · Dbp79E · anon-79E · CG9054 · Dead-box-1 · DmDDX1 · Ddx1) · UniProtKB:Q9VNV3
D. melanogaster	FB:FBgn0000171 (anon-85Ab · DmRH6 · ms(3)Pneo85A · l(3)L3 · cap · cg9748 · capon · BEL · belle · CG9748 · L3 · Belle · Bel · bel · l(3)S097074 · ms(3)neo30 · l(3)85Ac) · UniProtKB:Q9VHP0
D. melanogaster	FB:FBgn0015331 (l(3)04505 · l(3)06863 · abs · anon-WO0118547.315 · l(3)00620 · l(3)06862 · CG14637 · ABS · abstract · abstrakt · DmRH23) · UniProtKB:Q9V3C0
D. melanogaster	UniProtKB:Q07886 · FB:FBgn0010220 (Dbp45 · DmRH18 · dbp45A · CG12759 · Dbp45A · DBP45A)	ATP-dependent RNA helicase · DEAD box protein 45A
D. melanogaster	UniProtKB:P26802 · FB:FBgn0004556 (DmRH7 · DBP73D · CG9680 · Dbp73D)	Dead box protein 73D
D. melanogaster	FB:FBgn0037561 (CG9630 · cg9630 · DmRH16) · UniProtKB:Q9VHU1
D. melanogaster	UniProtKB:P23128 · FB:FBgn0004419 (Me31b · Me31B · CG4916 · me31B · ME31B · Dhh1p/Me31b · l(2)k06607 · Mat31B · DmRH3)	maternal expression at 31B
D. melanogaster	UniProtKB:Q02748 · FB:FBgn0001942 (eIF-4a-I · eIF-4a · eIF4A · anon-26Aa · Eif-4a · l(2L)162 · eif4A · eIF-4A · l(2)162 · l(2)k01501 · Dm-eIF4A · CG9075 · Eif4a · Su(dpp)YE9 · EIF-4A · l(2)gdh-4 · l(2)26Ac · eif-4a · l(2)02439 · 2439 · DmRH2 · anon26A · EiF4A)	eukaryotic translation initiation factor 4A · Eukaryotic initiation factor 4a
D. melanogaster	UniProtKB:Q27268 · FB:FBgn0014189 (Hel · uap56 · jf26 · l(2)k11511 · sz · lethal(2)25Eb · Dbp25F · hel · l(2)gdh-12 · CG7269 · UAP56 · l(2)gdh12 · HEL · l(2)jf26 · Hel25E · Wm6 · DmRH4 · WM6 · helicase · l(2)25Eb)	Helicase at 25E · RNA helicase
D. melanogaster	UniProtKB:P09052 · FB:FBgn0003970 (vasa · pf7 · EP(2)0812 · cgt · CG3506 · courgette · DmRH25 · BG:DS00929.14 · Vas · no-relish · Vasa · fs(2)ltoRJ36 · vas · VAS · VASA)	female sterile(2)ltoRJ36
D. melanogaster	FB:FBgn0029880 (CG14443 · cg14443) · UniProtKB:Q9W3Y5
D. melanogaster	FB:FBgn0034496 (cg9143 · CG9143) · UniProtKB:Q6NQY9
D. melanogaster	FB:FBgn0021995 (cg2173 · CG2173 · DmRH21 · BcDNA:GM05306 · 153844_at · Drs1 · l(2)k09514 · Rs1) · UniProtKB:Q7JQN4
D. melanogaster	FB:FBgn0037549 (CG7878 · DmRH26 · cg7878) · UniProtKB:Q7K4L8
D. melanogaster	FB:FBgn0027602 (CG8611 · DmRH11 · BcDNA:GH02833 · cg8611) · UniProtKB:Q86B47
D. melanogaster	FB:FBgn0035720 (CG10077 · BcDNA:HL07910 · p90 · cg10077 · DmRH5 · BcDNA:HL01868) · UniProtKB:Q8MZI3
D. melanogaster	FB:FBgn0052344 (cg6994 · DmRH20 · CG6994 · CG32344) · UniProtKB:Q8SY39
D. melanogaster	UniProtKB:Q9V3C4 · FB:FBgn0011802 (Gemin3 · Gem3 · DHH1 · DmRH22 · dGem3 · BcDNA.LD05563 · CG6539 · l(3)rL562 · Dhh1 · dGemin3 · BcDNA:LD05563)	DEAD/DEAH RNA helicase 1
D. melanogaster	UniProtKB:Q9V433 · FB:FBgn0027375 (RECQ5/QE · dmRecQ5b · Dq1 · DQ1 · CG4879 · Q1 · RecQ5 · RECQ5 · anon-EST:Posey293 · RECQE · DmRECQ5)	homolog of RecQ · Drosophila homolog of RecQ · Dm RECQ5/QE
D. melanogaster	FB:FBgn0037573 (DmRH28 · eIF4AIII · eIF4A · anon-WO0118547.364 · l(3)84Fi · lethal(3)84Fi · CG7483 · eIF4A-III) · UniProtKB:Q9VHS8
D. melanogaster	FB:FBgn0032919 (CG9253 · anon-EST:GressD10 · DmRH24 · cg9253) · UniProtKB:Q9VIF6
D. melanogaster	FB:FBgn0032690 (DmRH19 · CG10333 · cg10333) · UniProtKB:Q9VJ74
D. melanogaster	FB:FBgn0086130 (DmRH9 · KH1 · cg3561 · CG3561) · UniProtKB:Q9VPT3
D. melanogaster	UniProtKB:Q9VRI0 · FB:FBgn0001565 (lA112 · l(1)S-19F6 · l(1)19Ff · l(1)A112 · 7 · DmRH10 · 11P1 · hlc · l(1)11P1 · HM-44 · CG1666 · Hlc · HLC · 14 · Helicase · lethal(1)19Ff · l11P1 · l(1)8-1 · helicase · A112)	section 7 · RNA helicase gene · section 14
D. melanogaster	FB:FBgn0036104 (CG6418 · DmRH27 · cg6418) · UniProtKB:Q9VTC1
D. melanogaster	FB:FBgn0036754 (cg5589 · DmRH17 · CG5589) · UniProtKB:Q9VVK8
D. melanogaster	FB:FBgn0030855 (DmRH14 · CG5800 · cg5800) · UniProtKB:Q9VX34
D. melanogaster	FB:FBgn0030631 (cg6227 · Prp5 · DmRH29 · CG6227) · UniProtKB:Q9VXW2
D. melanogaster	FB:FBgn0029979 (DmRH1 · cg10777 · CG10777) · UniProtKB:Q9W3M7
E. coli	UniProtKB:P21693 · ECOLI:EG10210-MONOMER (rhlC · B1343 · DbpA · b1343 · dbpA · ECK1340 · RhlC)	ATP-dependent RNA helicase, specific for 23S rRNA · ATP-dependent RNA helicase · DEAD box RNA helicase and RNA-dependent ATPase · specific for 23S rRNA
E. coli	UniProtKB:P0A9P6 · ECOLI:EG10215-MONOMER (deaD · ECK3150 · b3162 · csdA · mssB · CsdA · rhlD)	CsdA, DEAD-box RNA helicase
E. coli	UniProtKB:P15043 · ECOLI:EG10833-MONOMER (RecQ · b3822 · recQ · B3822 · ECK3816)	ATP-dependent DNA helicase
E. coli	UniProtKB:P0A8J8 · ECOLI:EG10844-MONOMER (rhlB · RhlB · mmrA · ECK3772 · b3780)
E. coli	UniProtKB:P25888 · ECOLI:EG11235-MONOMER (b0797 · RhlE · rhlE · ECK0786)	ATP-dependent RNA helicase
E. coli	UniProtKB:P21507 · ECOLI:EG10975-MONOMER (rhlA · b2576 · rbaB · ECK2574 · srmB · SrmB)	SrmB, DEAD-box RNA helicase
G. gallus	NCBI:XP_417996 · ENTREZ:419869
G. gallus	NCBI:XP_001235033 · ENTREZ:422505
G. gallus	NCBI:XP_421574 · ENTREZ:423693
G. gallus	NCBI:XP_001232052 · ENTREZ:768898
G. gallus	NCBI:XP_424667 · ENTREZ:427073
G. gallus	NCBI:XP_416260 · ENTREZ:418024
G. gallus	NCBI:XP_415229 · ENTREZ:416936
G. gallus	NCBI:XP_425202 · ENTREZ:427630
G. gallus	NCBI:XP_425332 · ENTREZ:427759
G. gallus	NCBI:XP_427538 · ENTREZ:429982
G. gallus	NCBI:XP_422189 · ENTREZ:424346
G. gallus	NCBI:XP_001233565 · ENTREZ:373891
G. gallus	NCBI:XP_421338 · ENTREZ:423429
G. gallus	NCBI:XP_414629 · ENTREZ:416312
G. gallus	NCBI:XP_422125 · ENTREZ:424278
G. gallus	NCBI:XP_426195 · ENTREZ:428637
G. gallus	ENTREZ:418965 · UniProtKB:Q5ZJF6 (IPI00595697 · DDX10_CHICK · Q5ZJF6 · RCJMB04_18j24 · DDX10)	Probable ATP-dependent RNA helicase DDX10
G. gallus	ENTREZ:395249 · UniProtKB:Q90WU3 (DDX1_CHICK · IPI00585086 · DDX1 · Q90WU3)	ATP-dependent RNA helicase DDX1
G. gallus	ENTREZ:419959 · UniProtKB:Q5F485 (RCJMB04_2e15 · DDX42_CHICK · IPI00576529 · DDX42 · Q5F485)	ATP-dependent RNA helicase DDX42
G. gallus	ENTREZ:416820 · UniProtKB:Q5ZLN8 (RCJMB04_5g4 · Q5ZLN8 · DDX55_CHICK · DDX55 · IPI00590534)	ATP-dependent RNA helicase DDX55
G. gallus	ENTREZ:419783 · UniProtKB:Q5ZKB9 (RCJMB04_11n24 · Q5ZKB9 · DDX6 · DDX6_CHICK · IPI00595692)	Probable ATP-dependent RNA helicase DDX6
G. gallus	ENTREZ:395232 · UniProtKB:Q8JFP1 (IF4A2_CHICK · IPI00588868 · EIF4A2 · Q8JFP1 · RCJMB04_14a6)	Eukaryotic initiation factor 4A-II
G. gallus	UniProtKB:Q5F3Y6 (IPI00822952 · Q5F3Y6 · RCJMB04_4d17) · ENTREZ:417660
G. gallus	UniProtKB:Q5F491 (IPI00579247 · RCJMB04_2a4 · Q5F491) · ENTREZ:418567
G. gallus	UniProtKB:Q5ZJM1 (Q5ZJM1 · IPI00585933 · RCJMB04_17c23) · ENTREZ:415577
G. gallus	UniProtKB:Q5ZLA8 (Q5ZLA8 · RCJMB04_6o15 · IPI00684751) · ENTREZ:420116
G. gallus	UniProtKB:Q5ZLB0 (RCJMB04_6o10 · Q5ZLB0 · IPI00584081) · ENTREZ:417959
G. gallus	UniProtKB:Q5ZLD0 (RCJMB04_6k21 · Q5ZLD0 · IPI00579774) · ENTREZ:419308
G. gallus	UniProtKB:Q5ZM36 (Q5ZM36 · IPI00588271 · RCJMB04_3e17) · ENTREZ:416704
G. gallus	UniProtKB:Q5ZMC1 (IPI00571485 · Q5ZMC1 · RCJMB04_2i24) · ENTREZ:426504
G. gallus	UniProtKB:Q8AYS4 (RECQL1 · IPI00602593 · Q8AYS4) · ENTREZ:378910
G. gallus	UniProtKB:Q9DGR8 (IPI00578446 · Q9DGR8) · ENTREZ:395447
G. gallus	UniProtKB:Q9W744 (Q9W744 · IPI00598253) · ENTREZ:395629
H. sapiens	ENSEMBL:ENSG00000197299 · UniProtKB:P54132 (RECQ2 · BLM_HUMAN · P54132 · IPI00004859 · BLM · RECQL3)	Bloom syndrome protein
H. sapiens	ENSEMBL:ENSG00000168872 · UniProtKB:Q9NUU7 (DDX19L · Q9NUU7 · DD19A_HUMAN · DDX19A · IPI00019918)	ATP-dependent RNA helicase DDX19A
H. sapiens	ENSEMBL:ENSG00000157349 · UniProtKB:Q9UMR2 (IPI00008943 · DBP5 · DD19B_HUMAN · IPI00027599 · DDX19 · DDX19B · Q9UMR2)	ATP-dependent RNA helicase DDX19B
H. sapiens	ENSEMBL:ENSG00000178105 · UniProtKB:Q13206 (DDX10_HUMAN · IPI00297900 · DDX10 · Q13206)	Probable ATP-dependent RNA helicase DDX10
H. sapiens	ENSEMBL:ENSG00000100201 · UniProtKB:Q92841 (Q92841 · IPI00023785 · DDX17_HUMAN · IPI00651677 · DDX17 · IPI00651653)	Probable ATP-dependent RNA helicase DDX17
H. sapiens	ENSEMBL:ENSG00000088205 · UniProtKB:Q9NVP1 (Q9NVP1 · DDX18 · IPI00301323 · DDX18_HUMAN)	ATP-dependent RNA helicase DDX18
H. sapiens	ENSEMBL:ENSG00000079785 · UniProtKB:Q92499 (DDX1 · DDX1_HUMAN · IPI00293655 · Q92499)	ATP-dependent RNA helicase DDX1
H. sapiens	ENSEMBL:ENSG00000064703 · UniProtKB:Q9UHI6 (DDX20_HUMAN · Q9UHI6 · DDX20 · IPI00005904 · GEMIN3 · DP103)	Probable ATP-dependent RNA helicase DDX20
H. sapiens	ENSEMBL:ENSG00000165732 · UniProtKB:Q9NR30 (DDX21 · IPI00477179 · Q9NR30 · DDX21_HUMAN · IPI00015953)	Nucleolar RNA helicase 2
H. sapiens	ENSEMBL:ENSG00000174243 · UniProtKB:Q9BUQ8 (IPI00006725 · DDX23 · Q9BUQ8 · DDX23_HUMAN)	Probable ATP-dependent RNA helicase DDX23
H. sapiens	ENSEMBL:ENSG00000089737 · UniProtKB:Q9GZR7 (IPI00006987 · DDX24 · DDX24_HUMAN · Q9GZR7)	ATP-dependent RNA helicase DDX24
H. sapiens	ENSEMBL:ENSG00000109832 · UniProtKB:Q9UHL0 (IPI00296139 · DDX25 · Q9UHL0 · DDX25_HUMAN · IPI00759454 · GRTH)	ATP-dependent RNA helicase DDX25
H. sapiens	ENSEMBL:ENSG00000124228 · UniProtKB:Q96GQ7 (HSPC259 · IPI00293078 · PP3241 · RHLP · DDX27 · DDX27_HUMAN · Q96GQ7)	Probable ATP-dependent RNA helicase DDX27
H. sapiens	ENSEMBL:ENSG00000182810 · UniProtKB:Q9NUL7 (DDX28_HUMAN · Q9NUL7 · IPI00020050 · MDDX28 · DDX28)	Probable ATP-dependent RNA helicase DDX28
H. sapiens	ENSEMBL:ENSG00000125485 · UniProtKB:Q9H8H2 (IPI00552716 · IPI00552374 · DDX31 · IPI00291296 · Q9H8H2 · DDX31_HUMAN · IPI00043990)	Probable ATP-dependent RNA helicase DDX31
H. sapiens	ENSEMBL:ENSG00000123136 · UniProtKB:O00148 (DDX39_HUMAN · IPI00644431 · O00148 · DDX39)	ATP-dependent RNA helicase DDX39
H. sapiens	ENSEMBL:ENSG00000215301 · UniProtKB:O00571 (DDX3X · O00571 · DDX3 · IPI00215637 · DBX · DDX3X_HUMAN)	ATP-dependent RNA helicase DDX3X
H. sapiens	ENSEMBL:ENSG00000067048 · UniProtKB:O15523 (DBY · DDX3Y_HUMAN · O15523 · DDX3Y · IPI00293616)	ATP-dependent RNA helicase DDX3Y
H. sapiens	ENSEMBL:ENSG00000183258 · UniProtKB:Q9UJV9 (DDX41_HUMAN · DDX41 · ABS · IPI00007208 · Q9UJV9)	Probable ATP-dependent RNA helicase DDX41
H. sapiens	ENSEMBL:ENSG00000198231 · UniProtKB:Q86XP3 (DDX42_HUMAN · Q86XP3 · IPI00409671 · DDX42 · IPI00829889)	ATP-dependent RNA helicase DDX42
H. sapiens	ENSEMBL:ENSG00000080007 · UniProtKB:Q9NXZ2 (IPI00032899 · DDX43_HUMAN · DDX43 · Q9NXZ2 · HAGE)	Probable ATP-dependent RNA helicase DDX43
H. sapiens	ENSEMBL:ENSG00000145833 · UniProtKB:Q7L014 (DDX46 · KIAA0801 · IPI00329791 · Q7L014 · DDX46_HUMAN)	Probable ATP-dependent RNA helicase DDX46
H. sapiens	ENSEMBL:ENSG00000213782 · UniProtKB:Q9H0S4 (DDX47_HUMAN · DDX47 · Q9H0S4 · IPI00023972)	Probable ATP-dependent RNA helicase DDX47
H. sapiens	ENSEMBL:ENSG00000105671 · UniProtKB:Q9Y6V7 (Q9Y6V7 · IPI00003739 · DDX49 · DDX49_HUMAN)	Probable ATP-dependent RNA helicase DDX49
H. sapiens	ENSEMBL:ENSG00000152670 · UniProtKB:Q9NQI0 (DDX4 · IPI00456933 · DDX4_HUMAN · VASA · Q9NQI0 · IPI00071483)	Probable ATP-dependent RNA helicase DDX4
H. sapiens	ENSEMBL:ENSG00000107625 · UniProtKB:Q9BQ39 (DDX50 · DDX50_HUMAN · Q9BQ39 · IPI00031554)	ATP-dependent RNA helicase DDX50
H. sapiens	ENSEMBL:ENSG00000185163 · UniProtKB:Q8N8A6 (IPI00217541 · DDX51_HUMAN · DDX51 · Q8N8A6)	ATP-dependent RNA helicase DDX51
H. sapiens	ENSEMBL:ENSG00000141141 · UniProtKB:Q9Y2R4 (DDX52_HUMAN · Q9Y2R4 · IPI00032423 · HUSSY-19 · DDX52 · ROK1)	Probable ATP-dependent RNA helicase DDX52
H. sapiens	ENSEMBL:ENSG00000184735 · UniProtKB:Q86TM3 (DDX53_HUMAN · CAGE · Q86TM3 · IPI00328813 · DDX53)	Probable ATP-dependent RNA helicase DDX53
H. sapiens	ENSEMBL:ENSG00000123064 · UniProtKB:Q8TDD1 (DDX54 · DDX54_HUMAN · Q8TDD1 · IPI00879999)	ATP-dependent RNA helicase DDX54
H. sapiens	ENSEMBL:ENSG00000111364 · UniProtKB:Q8NHQ9 (IPI00185361 · Q8NHQ9 · DDX55 · DDX55_HUMAN · KIAA1595)	ATP-dependent RNA helicase DDX55
H. sapiens	ENSEMBL:ENSG00000136271 · UniProtKB:Q9NY93 (DDX21 · DDX56 · IPI00302281 · Q9NY93 · NOH61 · DDX56_HUMAN)	Probable ATP-dependent RNA helicase DDX56
H. sapiens	ENSEMBL:ENSG00000118197 · UniProtKB:Q5T1V6 (DDX59 · DDX59_HUMAN · IPI00010449 · IPI00217157 · ZNHIT5 · Q5T1V6)	Probable ATP-dependent RNA helicase DDX59
H. sapiens	ENSEMBL:ENSG00000108654 · UniProtKB:P17844 (HLR1 · DDX5 · IPI00017617 · DDX5_HUMAN · HELR · G17P1 · P17844)	Probable ATP-dependent RNA helicase DDX5
H. sapiens	ENSEMBL:ENSG00000110367 · UniProtKB:P26196 (RCK · HLR2 · P26196 · DDX6_HUMAN · DDX6 · IPI00030320)	Probable ATP-dependent RNA helicase DDX6
H. sapiens	ENSEMBL:ENSG00000161960 · UniProtKB:P60842 (IPI00025491 · DDX2A · EIF4A1 · P60842 · IF4A1_HUMAN · EIF4A)	Eukaryotic initiation factor 4A-I
H. sapiens	ENSEMBL:ENSG00000156976 · UniProtKB:Q14240 (IF4A2_HUMAN · EIF4A2 · IPI00328328 · EIF4F · Q14240 · DDX2B · IPI00409717)	Eukaryotic initiation factor 4A-II
H. sapiens	ENSEMBL:ENSG00000141543 · UniProtKB:P38919 (IF4A3_HUMAN · P38919 · IPI00009328 · DDX48 · EIF4A3 · KIAA0111)	Eukaryotic initiation factor 4A-III
H. sapiens	ENSEMBL:ENSG00000004700 · UniProtKB:P46063 (IPI00178431 · RECQL1 · RECQ1_HUMAN · RECQL · P46063)	ATP-dependent DNA helicase Q1
H. sapiens	ENSEMBL:ENSG00000108469 · UniProtKB:O94762 (IPI00185769 · RECQ5 · IPI00220820 · IPI00220819 · RECQL5 · O94762 · RECQ5_HUMAN)	ATP-dependent DNA helicase Q5
H. sapiens	ENSEMBL:ENSG00000198563 · UniProtKB:Q13838 (Q13838 · UAP56_HUMAN · IPI00641829 · UAP56 · IPI00848161 · BAT1)	Spliceosome RNA helicase BAT1
H. sapiens	ENSEMBL:ENSG00000215412 · UniProtKB:Q13838 (Q13838 · UAP56_HUMAN · IPI00641829 · UAP56 · IPI00848161 · BAT1)	Spliceosome RNA helicase BAT1
H. sapiens	ENSEMBL:ENSG00000215425 · UniProtKB:Q13838 (Q13838 · UAP56_HUMAN · IPI00641829 · UAP56 · IPI00848161 · BAT1)	Spliceosome RNA helicase BAT1
H. sapiens	ENSEMBL:ENSG00000165392 · UniProtKB:Q14191 (RECQL2 · Q14191 · WRN_HUMAN · IPI00029107 · WRN · RECQ3)	Werner syndrome ATP-dependent helicase
M. musculus	NCBI:NP_001136206 · MGI:MGI:3644226
M. musculus	NCBI:NP_569721 · MGI:MGI:2156841 (Recql5b · Recq5b · Recql5)	RecQ protein-like 5
M. musculus	NCBI:NP_001074450 · MGI:MGI:1921601 (Ddx23)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
M. musculus	NCBI:XP_001478904 · MGI:MGI:3642857
M. musculus	NCBI:XP_485792 · MGI:MGI:3644832
M. musculus	NCBI:XP_484782 · MGI:MGI:3645437
M. musculus	NCBI:NP_758488 · MGI:MGI:2148251 (Ddx19b)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
M. musculus	NCBI:NP_001028466 · MGI:MGI:2682639 (Ddx31)	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31
M. musculus	UniProtKB:O88700 · MGI:MGI:1328362 (Blm)	Bloom syndrome homolog (human)
M. musculus	UniProtKB:Q61655 · MGI:MGI:99526 (Ddx19a · DBP5 · Eif4a-rs1 · Ddx19)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
M. musculus	UniProtKB:Q80Y44 · MGI:MGI:1924841 (Ddx10)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
M. musculus	UniProtKB:Q501J6 · MGI:MGI:1914290 (LOC381024 · Ddx17 · p72)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
M. musculus	UniProtKB:Q8K363 · MGI:MGI:1914192 (Ddx18)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
M. musculus	UniProtKB:Q91VR5 · MGI:MGI:2144727 (Ddx1)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
M. musculus	UniProtKB:Q9JJY4 · MGI:MGI:1858415 (Ddx20 · GEMIN3 · dp103)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
M. musculus	UniProtKB:Q9JIK5 · MGI:MGI:1860494 (RH-II/Gualpha · D10Ertd645e · Ddx21 · D10Wsu42e)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 · RH II/Gu
M. musculus	UniProtKB:Q9ESV0 · MGI:MGI:1351337 (Ddx24)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
M. musculus	UniProtKB:Q9QY15 · MGI:MGI:1353582 (Ddx25 · GRTH)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
M. musculus	UniProtKB:Q921N6 · MGI:MGI:2385884 (Ddx27)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
M. musculus	UniProtKB:Q9CWT6 · MGI:MGI:1919236 (Mddx28 · Ddx28)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
M. musculus	UniProtKB:Q8VDW0 · MGI:MGI:1915528 (Ddx39 · BAT1)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
M. musculus	UniProtKB:P16381 · MGI:MGI:91842 (Pl10 · D1Pas1)	DNA segment, Chr 1, Pasteur Institute 1
M. musculus	UniProtKB:Q62167 · MGI:MGI:103064 (D1Pas1-rs2 · Ddx3x · Fin14 · Ddx3)	embryonic RNA helicase · DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
M. musculus	UniProtKB:Q62095 · MGI:MGI:1349406 (Ddx3y · D1Pas1-rs1 · Dby)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
M. musculus	UniProtKB:Q91VN6 · MGI:MGI:1920185 (Ddx41)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
M. musculus	UniProtKB:Q810A7 · MGI:MGI:1919297 (Ddx42 · SF3b125)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
M. musculus	UniProtKB:Q569Z5 · MGI:MGI:1920895 (Ddx46)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
M. musculus	UniProtKB:Q9CWX9 · MGI:MGI:1915005 (Ddx47)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
M. musculus	UniProtKB:Q4FZF3 · MGI:MGI:2136689 (R27090_2 · Ddx49)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
M. musculus	UniProtKB:Q61496 · MGI:MGI:102670 (VASA · Ddx4 · Mvh)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 · mvh / m'vasa
M. musculus	UniProtKB:Q99MJ9 · MGI:MGI:2182303 (GU2 · RH-II/Gubeta · Ddx50)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
M. musculus	UniProtKB:Q6P9R1 · MGI:MGI:1916913 (Ddx51)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
M. musculus	UniProtKB:Q8K301 · MGI:MGI:1925644 (Ddx52 · ROK1)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
M. musculus	UniProtKB:Q8K4L0 · MGI:MGI:1919240 (APR-5 · DP97 · Ddx54)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
M. musculus	UniProtKB:Q6ZPL9 · MGI:MGI:1915098 (Ddx55)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
M. musculus	UniProtKB:Q9D0R4 · MGI:MGI:1277172 (D11Ertd619e · NOH61 · Ddx56)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
M. musculus	UniProtKB:Q9DBN9 · MGI:MGI:1915247 (Ddx59)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
M. musculus	UniProtKB:Q61656 · MGI:MGI:105037 (Hlr1 · p68 · Ddx5)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
M. musculus	UniProtKB:P54823 · MGI:MGI:104976 (p54 · HLR2 · rck · Ddx6 · mRCK/P54)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
M. musculus	UniProtKB:P60843 · MGI:MGI:95303 (Eif4a1 · Eif4)	initiation factor eIF-4A long form · eukaryotic translation initiation factor 4A1
M. musculus	UniProtKB:P10630 · MGI:MGI:106906 (BM-010 · Eif4 · Eif4a2 · Ddx2b)	eukaryotic translation initiation factor 4A2
M. musculus	UniProtKB:Q91VC3 · MGI:MGI:1923731 (Ddx48 · Eif4a3)	eukaryotic translation initiation factor 4A, isoform 3
M. musculus	UniProtKB:Q9Z129 · MGI:MGI:103021 (RecQ1 · Recql)	RecQ protein-like
M. musculus	UniProtKB:Q9Z1N5 · MGI:MGI:99240 (D17H6S81E-1 · Bat1 · Bat-1 · Bat1a)	HLA-B-associated transcript 1A
M. musculus	UniProtKB:O09053 · MGI:MGI:109635 (Wrn)	Werner syndrome homolog (human)
M. musculus	MGI:MGI:3646594 · UniProtKB:B2RY38
R. norvegicus	NCBI:XP_214290 · RGD:1311124 (Ddx49)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
R. norvegicus	NCBI:XP_001064233 · RGD:1311758 (Ddx41)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
R. norvegicus	NCBI:XP_001059940 · RGD:1564788 (RGD1564788)	similar to Werner syndrome helicase homolog
R. norvegicus	NCBI:XP_001066609 · RGD:1309586
R. norvegicus	NCBI:XP_001079855 · RGD:1562539 (Ddx54)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
R. norvegicus	NCBI:XP_576400 · RGD:1564560
R. norvegicus	NCBI:XP_001066539 · RGD:1308810 (Blm)	Bloom syndrome homolog (human)
R. norvegicus	NCBI:XP_222149 · RGD:1311798
R. norvegicus	NCBI:XP_001075251 · RGD:1593382 (LOC690693)	similar to DDX19 homolog
R. norvegicus	NCBI:XP_228701 · RGD:1564771 (Ddx3x)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
R. norvegicus	NCBI:XP_001076081 · RGD:1311976 (Ddx28)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
R. norvegicus	NCBI:XP_001060655 · RGD:1308685 (Ddx23)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
R. norvegicus	NCBI:XP_001079567 · RGD:1597026 (LOC500654)	similar to eukaryotic translation initiation factor 4A, isoform 1
R. norvegicus	NCBI:XP_221037 · RGD:1304909
R. norvegicus	NCBI:XP_001059856 · RGD:1559513
R. norvegicus	NCBI:XP_001079220 · RGD:1304895 (Ddx31)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
R. norvegicus	NCBI:XP_236263 · RGD:1308990 (Ddx10)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
R. norvegicus	NCBI:XP_222252 · RGD:1309580
R. norvegicus	NCBI:XP_001060057 · RGD:1586947 (LOC682138)	similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
R. norvegicus	NCBI:XP_577779 · RGD:1566392
R. norvegicus	NCBI:XP_237812 · RGD:1310823
R. norvegicus	NCBI:XP_001081873 · RGD:1590027 (LOC688346)	similar to Probable ATP-dependent RNA helicase DDX27 (DEAD box protein 27)
R. norvegicus	RGD:619903 (Ddx1) · UniProtKB:Q641Y8 (DDX1_RAT · Q641Y8 · IPI00555314 · Ddx1)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 · ATP-dependent RNA helicase DDX1
R. norvegicus	UniProtKB:Q3B8Q1 · RGD:1307306 (Ddx21)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
R. norvegicus	RGD:68381 (Ddx25) · UniProtKB:Q9QY16 (Ddx25 · IPI00213497 · IPI00760145 · DDX25_RAT · Grth · IPI00760150 · Q9QY16)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 · ATP-dependent RNA helicase DDX25
R. norvegicus	UniProtKB:Q5U216 · RGD:619920 (Ddx39)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
R. norvegicus	UniProtKB:Q62780 · RGD:708480 (Ddx46)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
R. norvegicus	UniProtKB:Q64060 · RGD:1308793 (Ddx4)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
R. norvegicus	UniProtKB:Q99PT0 · RGD:621743 (Ddx52)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
R. norvegicus	UniProtKB:Q66HG7 · RGD:1359520 (Ddx59)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
R. norvegicus	UniProtKB:Q5RKI1 · RGD:1309225 (Eif4a2)	eukaryotic translation initiation factor 4A2
R. norvegicus	UniProtKB:Q6AYJ1 · RGD:1311071 (Recql)	RecQ protein-like (DNA helicase Q1-like)
R. norvegicus	UniProtKB:Q63413 · RGD:1303186 (Atp6v1g2)	ATPase, H+ transporting, lysosomal V1 subunit G2
R. norvegicus	UniProtKB:Q63413 · RGD:70923 (Bat1)	HLA-B associated transcript 1
R. norvegicus	UniProtKB:Q3B8Q2 · RGD:1591139 (Eif4a3)	eukaryotic translation initiation factor 4A, isoform 3
R. norvegicus	UniProtKB:Q5BIZ6 · RGD:1310437 (Ddx47)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
R. norvegicus	UniProtKB:Q5XHY0 · RGD:1549712 (Ddx18)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
R. norvegicus	UniProtKB:Q64LD0 · RGD:1303136 (Ddx19a)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
R. norvegicus	UniProtKB:Q64LD0 · RGD:1554298 (Ddx19_v2)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19, splice variant 2
R. norvegicus	UniProtKB:Q64LD0 · RGD:1554295
R. norvegicus	UniProtKB:Q6AYI1 · RGD:619906 (Ddx5)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
R. norvegicus	UniProtKB:Q6AYT6 · RGD:1303195 (Ddx56)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
R. norvegicus	UniProtKB:Q6P3V8 · RGD:735141 (Eif4a1)	eukaryotic translation initiation factor 4A1
R. norvegicus	UniProtKB:Q6VEU8 · RGD:727929 (Ddx24)	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
S. cerevisiae	UniProtKB:Q12389 · SGD:S000002189 (DBP10 · YDL031W)	Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles
S. cerevisiae	UniProtKB:P24784 · SGD:S000006040 (YPL119C · DBP1 · LPH8)	Putative ATP-dependent RNA helicase of the DEAD-box protein family
S. cerevisiae	UniProtKB:P24783 · SGD:S000005056 (DBP2 · YNL112W)	Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
S. cerevisiae	UniProtKB:P20447 · SGD:S000003046 (YGL078C · DBP3)	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
S. cerevisiae	UniProtKB:P20448 · SGD:S000003570 (ECM24 · DBP4 · HCA4 · YJL033W)	Putative nucleolar DEAD box RNA helicase
S. cerevisiae	UniProtKB:P20449 · SGD:S000005572 (RAT8 · DBP5 · YOR046C)	Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus
S. cerevisiae	UniProtKB:P53734 · SGD:S000005321 (YNR038W · DBP6)	Essential protein involved in ribosome biogenesis
S. cerevisiae	UniProtKB:P36120 · SGD:S000001732 (YKR024C · DBP7)	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
S. cerevisiae	UniProtKB:P38719 · SGD:S000001212 (DBP8 · YHR169W)	ATPase, putative RNA helicase of the DEAD-box family
S. cerevisiae	UniProtKB:Q06218 · SGD:S000004266 (YLR276C · DBP9)	ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit
S. cerevisiae	UniProtKB:P06634 · SGD:S000005730 (DED1 · SPP81 · YOR204W)	ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs
S. cerevisiae	UniProtKB:P39517 · SGD:S000002319 (DHH1 · YDL160C)	Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation
S. cerevisiae	UniProtKB:P32892 · SGD:S000003931 (DRS1 · YLL008W)	Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits
S. cerevisiae	UniProtKB:Q12099 · SGD:S000002428 (FAL1 · YDR021W)	Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases
S. cerevisiae	UniProtKB:Q03532 · SGD:S000004903 (YMR290C · HAS1)	ATP-dependent RNA helicase
S. cerevisiae	UniProtKB:P10081 · SGD:S000001767 (YKR059W · TIF1)	Translation initiation factor eIF4A, identical to Tif2p
S. cerevisiae	UniProtKB:P10081 · SGD:S000003674 (TIF2 · YJL138C)	Translation initiation factor eIF4A, identical to Tif1p
S. cerevisiae	UniProtKB:P38112 · SGD:S000000346 (YBR142W · MAK5)	Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus
S. cerevisiae	UniProtKB:P53166 · SGD:S000003032 (YGL064C · MRH4)	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function
S. cerevisiae	UniProtKB:P15424 · SGD:S000002602 (MSS116 · YDR194C)	DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns
S. cerevisiae	UniProtKB:P23394 · SGD:S000002651 (PRP28 · YDR243C)	RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site
S. cerevisiae	UniProtKB:P21372 · SGD:S000000441 (YBR237W · PRP5 · RNA5)	RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
S. cerevisiae	UniProtKB:P45818 · SGD:S000003139 (YGL171W · ROK1)	ATP-dependent RNA helicase of the DEAD box family
S. cerevisiae	UniProtKB:P38712 · SGD:S000001107 (RRP3 · YHR065C)	Protein involved in rRNA processing
S. cerevisiae	UniProtKB:P35187 · SGD:S000004802 (YMR190C · SGS1)	Nucleolar DNA helicase of the RecQ family involved in genome integrity maintenance
S. cerevisiae	UniProtKB:P25808 · SGD:S000001894 (YFL002C · SPB4)	Putative ATP-dependent RNA helicase, nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway
S. cerevisiae	UniProtKB:Q07478 · SGD:S000002242 (SUB2 · YDL084W)	Component of the TREX complex required for nuclear mRNA export
S. pombe	UniProtKB:Q09719 · GeneDB_Spombe:SPAC31A2.07c (SPAC31A2.07c · dbp10)	ATP-dependent RNA helicase Dbp10
S. pombe	UniProtKB:P24782 · GeneDB_Spombe:SPBP8B7.16c (SPBP8B7.16c · dbp2)	ATP-dependent RNA helicase Dbp2
S. pombe	UniProtKB:Q10202 · GeneDB_Spombe:SPBC17D1.06 (dbp3 · SPBC17D1.06)	ATP-dependent RNA helicase Dbp3
S. pombe	UniProtKB:Q9UTP9 · GeneDB_Spombe:SPAC1093.05 (SPAC1093.05)	ATP-dependent RNA helicase Hca4
S. pombe	UniProtKB:Q09747 · GeneDB_Spombe:SPBC12C2.06 (SPBC12C2.06)	ATP-dependent RNA helicase Dbp5
S. pombe	UniProtKB:Q76PD3 · GeneDB_Spombe:SPCC285.03 (SPCC285.03)	ATP-dependent RNA helicase Dbp6
S. pombe	UniProtKB:O60173 · GeneDB_Spombe:SPBC21H7.04 (dbp7 · SPBC21H7.04)	ATP-dependent RNA helicase Dbp7
S. pombe	UniProtKB:Q9HGM5 · GeneDB_Spombe:SPBC543.06c (SPBC543.06c · dbp8)	ATP-dependent RNA helicase Dbp8
S. pombe	UniProtKB:O60080 · GeneDB_Spombe:SPCC1494.06c (SPCC1494.06c)	ATP-dependent RNA helicase Dbp9
S. pombe	UniProtKB:O13370 · GeneDB_Spombe:SPCC1795.11 (sum3 · moc2 · slh3 · ded1 · SPCC1795.11)	ATP-dependent RNA helicase Sum3
S. pombe	UniProtKB:Q09181 · GeneDB_Spombe:SPBC776.09 (ste13 · SPBC776.09)	ATP-dependent RNA helicase Ste13
S. pombe	UniProtKB:Q09903 · GeneDB_Spombe:SPAC30D11.03 (ddx27 · drs1 · SPAC30D11.03)	ATP-dependent RNA helicase Ddx27/Drs1
S. pombe	UniProtKB:Q10055 · GeneDB_Spombe:SPAC1F5.10 (SPAC1F5.10)	ATP-dependent RNA helicase, eIF4A related
S. pombe	UniProtKB:Q09916 · GeneDB_Spombe:SPAC1F7.02c (SPAC1F7.02c)	ATP-dependent RNA helicase Has1
S. pombe	UniProtKB:Q09811 · GeneDB_Spombe:SPAC2G11.12 (SPAC2G11.12 · hus2 · rqh1 · rec9 · rad12)	RecQ type DNA helicase Rqh1
S. pombe	UniProtKB:P47943 · GeneDB_Spombe:SPAC1006.07 (SPAC1006.07)	translation initiation factor eIF4A
S. pombe	UniProtKB:O74393 · GeneDB_Spombe:SPBC4F6.07c (SPBC4F6.07c)	ATP-dependent RNA helicase Mak5
S. pombe	UniProtKB:O13622 · GeneDB_Spombe:SPBC691.04 (SPBC691.04)	mitochondrial ATP-dependent RNA helicase Mss116
S. pombe	UniProtKB:Q9P7C7 · GeneDB_Spombe:SPCC10H11.01 (prp11 · SPCC10H11.01)	ATP-dependent RNA helicase Prp11
S. pombe	UniProtKB:Q9Y7T7 · GeneDB_Spombe:SPCC63.11 (SPCC63.11 · prp28)	U5 snRNP-associated protein Prp28
S. pombe	UniProtKB:Q09775 · GeneDB_Spombe:SPAC22F3.08c (rok1 · SPAC22F3.08c)	ATP-dependent RNA helicase Rok1
S. pombe	UniProtKB:Q9P6N8 · GeneDB_Spombe:SPAC823.08c (SPAC823.08c)	ATP-dependent RNA helicase Rrp3
S. pombe	UniProtKB:O74764 · GeneDB_Spombe:SPBC24C6.02 (SPBC24C6.02)	ATP-dependent RNA helicase Spb4
S. pombe	UniProtKB:O13792 · GeneDB_Spombe:SPAC17G6.14c (uap56 · SPAC17G6.14c)	ATP-dependent RNA helicase Uap56

Protein	Publication	Curator Notes
UniProtKB:P06634 · SGD:S000005730	15572142 Johnstone O, et al. Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol. 2005 Jan 1;277(1):92-101.	The D. melanogaster protein CG9748-PA complements a homologous mutation in S. cerevisiae.
UniProtKB:P06634 · SGD:S000005730	10336476 Mamiya N, et al. Hepatitis C virus core protein binds to a DEAD box RNA helicase. J Biol Chem. 1999 May 28;274(22):15751-6.	The H. sapiens protein O00571 complements a homologous mutation in S. cerevisiae.
UniProtKB:P39517 · SGD:S000002319	12930949 Tseng-Rogenski SS, et al. Functional conservation of Dhh1p, a cytoplasmic DExD/H-box protein present in large complexes. Nucleic Acids Res. 2003 Sep 1;31(17):4995-5002.	The X. laevis protein Xp54 complements a homologous mutation in S. cerevisiae. This paper shows that overexpression of X. laevis Xp54 can complement a yeast dhh1 null mutant.
UniProtKB:Q03532 · SGD:S000004903	15049817 Emery B, et al. Has1p, a member of the DEAD-box family, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae. Mol Microbiol. 2004 Apr;52(1):141-58.	The C. albicans protein CaHAS1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P10081 · SGD:S000001767	2119809 Prat A, et al. Expression of translation initiation factor 4A from yeast and mouse in Saccharomyces cerevisiae. Biochim Biophys Acta. 1990 Aug 27;1050(1-3):140-5.	The M. musculus protein P10630 does not complement a homologous mutation in S. cerevisiae.
UniProtKB:P10081 · SGD:S000001767	2169888 Jaramillo M, et al. Translation initiation factors that function as RNA helicases from mammals, plants and yeast. Biochim Biophys Acta. 1990 Aug 27;1050(1-3):134-9.	The S. cerevisiae protein TIF1 was expressed in O. cuniculus, but complementation was not directly tested. Yeast eIF-4A was analyzed in a rabbit reticulocyte expression system.
UniProtKB:P35187 · SGD:S000004802	9671747 Yamagata K, et al. Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8733-8.	The H. sapiens protein P54132 complements a homologous mutation in S. cerevisiae. Mutation of SGS1 suppresses the slow-growth phenotype of top3 mutants; this paper shows that the Bloom's syndrome gene can restore the slow-growth phenotype of sgs1 top3 double mutants.
UniProtKB:P35187 · SGD:S000004802	15994923 Lillard-Wetherell K, et al. BLM helicase complements disrupted type II telomere lengthening in telomerase-negative sgs1 yeast. Cancer Res. 2005 Jul 1;65(13):5520-2.	The H. sapiens protein P54132 complements a homologous mutation in S. cerevisiae.
UniProtKB:P35187 · SGD:S000004802	9671747 Yamagata K, et al. Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8733-8.	The H. sapiens protein Q14191 does not complement a homologous mutation in S. cerevisiae.
UniProtKB:P35187 · SGD:S000004802	10069810 Neff NF, et al. The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells. Mol Biol Cell. 1999 Mar;10(3):665-76.	The H. sapiens protein P54132 complements a homologous mutation in S. cerevisiae. Human BLM partially complements the phenotypes assoicated with sgs1 mutations in a yeast sgs1 top3 double mutant.
UniProtKB:Q07478 · SGD:S000002242	15047853 Pryor A, et al. Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. Nucleic Acids Res. 2004;32(6):1857-65.	The H. sapiens protein O00148 complements a homologous mutation in S. cerevisiae.
UniProtKB:Q07478 · SGD:S000002242	15047853 Pryor A, et al. Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. Nucleic Acids Res. 2004;32(6):1857-65.	The H. sapiens protein Q13838 complements a homologous mutation in S. cerevisiae.

Description	Suffix
Sequences in this family	.fasta
mafft aligned Fasta file	.afasta
phyml newick file	.newick
Notung rooted & rearranged newick file	.newick.rooting.0.rearrange.0
Notung Homolog Table	.newick.rooting.0.rearrange.0.homologs.csv

OMIM (4)
ENSEMBL:ENSG00000067048 · UniProtKB:O15523	#210900 BLOOM SYNDROME; BLM;;BS; BLS
ENSEMBL:ENSG00000165392 · UniProtKB:Q14191	#400042 SERTOLI CELL-ONLY SYNDROME, Y-LINKED;;SERTOLI CELL-ONLY SYNDROME, TYPE ISERTOLI CELL-ONLY SYNDROME, TYPE II, INCLUDED;;HYPOSPERMATOGENESIS, INCLUDED;;INCOMPLETE SERTOLI CELL-ONLY SYNDROME, INCLUDED
UniProtKB:P06634 · SGD:S000005730	#277700 WERNER SYNDROME; WRN
	#114500 COLORECTAL CANCER; CRC;;COLON CANCER
SGD Disease Papers (45)
UniProtKB:P39517 · SGD:S000002319	15064363 Chong JL, et al. (2004) Ded1p, a conserved DExD/H-box translation factor, can promote yeast L-A virus negative-strand RNA synthesis in vitro. Nucleic Acids Res 32(6):2031-8
	10329544 Owsianka AM and Patel AH (1999) Hepatitis C virus core protein interacts with a human DEAD box protein DDX3. Virology 257(2):330-40
UniProtKB:P35187 · SGD:S000004802	15166134 Bergkessel M and Reese JC (2004) An essential role for the Saccharomyces cerevisiae DEAD-box helicase DHH1 in G1/S DNA-damage checkpoint recovery. Genetics 167(1):21-33
	12943812 Westmoreland TJ, et al. (2003) Dhh1 regulates the G1/S-checkpoint following DNA damage or BRCA1 expression in yeast. J Surg Res 113(1):62-73
UniProtKB:P35187 · SGD:S000004802	9671747 Yamagata K, et al. (1998) Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc Natl Acad Sci U S A 95(15):8733-8
	9618508 Marciniak RA, et al. (1998) Nucleolar localization of the Werner syndrome protein in human cells. Proc Natl Acad Sci U S A 95(12):6887-92
	9271578 Sinclair DA, et al. (1997) Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277(5330):1313-6
	9159160 Mushegian AR, et al. (1997) Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs. Proc Natl Acad Sci U S A 94(11):5831-6
	8913739 Watt PM, et al. (1996) SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144(3):935-45
	8878475 Lu J, et al. (1996) Human homologues of yeast helicase. Nature 383(6602):678-9
	8602509 Yu CE, et al. (1996) Positional cloning of the Werner's syndrome gene. Science 272(5259):258-62
	7585968 Ellis NA, et al. (1995) The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83(4):655-66
	18978339 Lan Q, et al. (2009) Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity. Carcinogenesis 30(1):50-8
	18701350 Barea F, et al. (2008) In silico analyses of a new group of fungal and plant RecQ4-homologous proteins. Comput Biol Chem 32(5):349-58
	18195102 Madia F, et al. (2008) Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. J Cell Biol 180(1):67-81
	17662941 Oh SD, et al. (2007) BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules. Cell 130(2):259-72
	17399687 Ui A, et al. (2007) Activation of a novel pathway involving Mms1 and Rad59 in sgs1 cells. Biochem Biophys Res Commun 356(4):1031-7
	17360454 Yuen KW, et al. (2007) Systematic genome instability screens in yeast and their potential relevance to cancer. Proc Natl Acad Sci U S A 104(10):3925-30
	16288211 Spillare EA, et al. (2006) Redundancy of DNA helicases in p53-mediated apoptosis. Oncogene 25(14):2119-23
	15803320 Yamana Y, et al. (2005) Regulation of homologous integration in yeast by the DNA repair proteins Ku70 and RecQ. Mol Genet Genomics 273(2):167-76
	15247043 Chen C and Contreras R (2004) The bud scar-based screening system for hunting human genes extending life span. Ann N Y Acad Sci 1019:355-9
	14749772 Heyer WD (2004) A new deal for Holliday junctions. Nat Struct Mol Biol 11(2):117-9
	14688284 Sharma S, et al. (2004) Stimulation of flap endonuclease-1 by the Bloom's syndrome protein. J Biol Chem 279(11):9847-56
	14622595 Ira G, et al. (2003) Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast. Cell 115(4):401-11
	12875747 Fry RC, et al. (2003) DNA damage and stress transcripts in Saccharomyces cerevisiae mutant sgs1. Mech Ageing Dev 124(7):839-46
	12638184 Miyajima A (2002) [Functional analysis of yeast homologue gene associated with human DNA helicase causative syndromes] Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku(120):53-74
	12354611 Cobb JA, et al. (2002) RecQ helicases: at the heart of genetic stability. FEBS Lett 529(1):43-8
	12235379 Huber MD, et al. (2002) G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. Nucleic Acids Res 30(18):3954-61
	12106656 Ajima J, et al. (2002) Elevated incidence of loss of heterozygosity (LOH) in an sgs1 mutant of Saccharomyces cerevisiae: roles of yeast RecQ helicase in suppression of aneuploidy, interchromosomal rearrangement, and the simultaneous incidence of both events during mitotic growth. Mutat Res 504(1-2):157-72
	11779799 Hofmann AF and Harris SD (2001) The Aspergillus nidulans musN gene encodes a RecQ helicase that interacts with the PI-3K-related kinase UVSB. Genetics 159(4):1595-604
	11389927 Mankouri HW and Morgan A (2001) The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors. Mech Ageing Dev 122(11):1107-20
	11305028 Yamagata Z (2001) [Longevity related genes] Nippon Ronen Igakkai Zasshi 38(2):166-8
	11231130 Huang P, et al. (2001) SGS1 is required for telomere elongation in the absence of telomerase. Curr Biol 11(2):125-9
	11212925 Onoda F, et al. (2001) Involvement of SGS1 in DNA damage-induced heteroallelic recombination that requires RAD52 in Saccharomyces cerevisiae. Mol Gen Genet 264(5):702-8
	11179234 Johnson FB, et al. (2001) The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO J 20(4):905-13
	10835635 Gangloff S, et al. (2000) Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases. Nat Genet 25(2):192-4
	10812332 Onoda F, et al. (2000) Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene. Mutat Res 459(3):203-9
	10734115 Wu L, et al. (2000) The Bloom's syndrome gene product interacts with topoisomerase III. J Biol Chem 275(13):9636-44
	10652259 Moens PB, et al. (2000) Expression and nuclear localization of BLM, a chromosome stability protein mutated in Bloom's syndrome, suggest a role in recombination during meiotic prophase. J Cell Sci 113 ( Pt 4):663-72
	10640278 Frei C and Gasser SM (2000) The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev 14(1):81-96
	10409756 White PJ, et al. (1999) Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism. Mol Cell Biol 19(8):5675-84
	10319867 Kitao S, et al. (1999) Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. Nat Genet 22(1):82-4
	10198430 Sun H, et al. (1999) The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res 27(9):1978-84
	10069810 Neff NF, et al. (1999) The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells. Mol Biol Cell 10(3):665-76
	10049920 Kusano K, et al. (1999) Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene. Genetics 151(3):1027-39